etidronate has been researched along with Body Weight in 44 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The birds were also injected daily with solutions containing ethane-1-hydroxy-1,1-diphosphonate (EHDP) at concentrations ranging from 5 to 20 mg as phosphorus/kg of body weight or isotonic saline." | 3.65 | Effects of fluoride and ethane-1-hydroxy-1,1-diphosphonate on bone metabolism in the growing chick. ( Chan, MM; Riggins, RS; Rucker, RB, 1976) |
| " Our data show that ED at a dosage that suppresses bone metabolism markedly inhibits vascular calcification in rats with renal failure." | 1.33 | Effect of etidronate on aortic calcification and bone metabolism in calcitriol-treated rats with subtotal nephrectomy. ( Aizawa, S; Hashiba, H; Kogo, H; Suzuki, Y; Tamura, H; Tamura, K, 2005) |
| "The purpose of the present study was to examine the effect of pretreatment with risedronate and/or vitamin K2 and treatment continuation with reduced dosing frequency of the drugs on the early cancellous bone loss induced by ovariectomy (OVX) in rats." | 1.33 | Beneficial effect of pretreatment and treatment continuation with risedronate and vitamin K2 on cancellous bone loss after ovariectomy in rats: a bone histomorphometry study. ( Iwamoto, J; Sato, Y; Shen, CL; Takeda, T; Yeh, JK, 2006) |
| "Etidronate treatment (10 mg/kg, daily subcutaneous injection) was initiated 2 weeks after surgery and was continued for 2 weeks." | 1.32 | Differential effect of short-term etidronate treatment on three cancellous bone sites in orchidectomized adult rats. ( Ichimura, S; Iwamoto, J; Takeda, T, 2004) |
| "The relationship between bone turnover and bone tissue and material properties was examined in ovariectomized (OVX) rats treated with risedronate in combination with or without vitamin K2." | 1.32 | Regulation of mineral-to-matrix ratio of lumbar trabecular bone in ovariectomized rats treated with risedronate in combination with or without vitamin K2. ( Ikeda, S; Ito, M; Nakamura, T; Otomo, H; Phipps, RJ; Sakai, A; Tanaka, S, 2004) |
| " The study was designed as a dose-response study, and the site-specific effects of immobilization and of treatment are described." | 1.31 | Treatment with risedronate or alendronate prevents hind-limb immobilization-induced loss of bone density and strength in adult female rats. ( Mackey, MS; Mosekilde, L; Phipps, RJ; Thomsen, JS, 2000) |
| "Etidronate treatment (10 mg/kg per day subcutaneously) was initiated 2 weeks after surgery and was continued for 2 weeks." | 1.31 | Effect of etidronate on bone in orchidectomized and sciatic neurectomized adult rats. ( Ichimura, S; Iwamoto, J; Katsumata, T; Takeda, T; Tanaka, T; Toyama, Y, 2002) |
| "The alendronate-treated group did not show significant alteration of the breaking load or the cross-sectional shape of the femoral midshaft." | 1.30 | Effects of continuous alendronate treatment on bone mass and mechanical properties in ovariectomized rats: comparison with pamidronate and etidronate in growing rats. ( Azuma, Y; Kanatani, H; Kiyoki, M; Komoriya, K; Ohta, T; Oue, Y, 1998) |
| " These findings indicated that the long-term administration of PGE2 alone cannot maintain or continue to add bone mass in ovx rats but that co-treatment of a PGE2 with an anti-resorptive or activation agent can resist the influence of the mechanostat induced bone loss as well as continue to add bone." | 1.29 | Co-treatment of PGE2 and risedronate is better than PGE2 alone in the long-term treatment of ovariectomized-induced osteopenic rats. ( Chen, YY; Ijiri, K; Jee, WS; Ke, HZ; Ma, Y, 1995) |
| "The present study was undertaken to test whether long term administration of HEBP could prevent the progress of bone loss induced by ovariectomy in rats." | 1.28 | Effect of HEBP (1-hydroxyethylidene-1,1-bisphosphonate) on experimental osteoporosis induced by ovariectomy in rats. ( Arai, M; Hironaka, M; Matsumoto, S; Shinoda, H; Togari, A, 1991) |
| " A dose-response study with two compounds also revealed the same close correlation." | 1.26 | Relation between bone mineralization, Ca absorption, and plasma Ca in phosphonate-treated rats. ( Bonjour, JP; Fleisch, H; Russell, RG; Schenk, R; Trechsel, U, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (29.55) | 18.7374 |
| 1990's | 10 (22.73) | 18.2507 |
| 2000's | 18 (40.91) | 29.6817 |
| 2010's | 3 (6.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iwamoto, J | 6 |
| Matsumoto, H | 1 |
| Takeda, T | 6 |
| Sato, Y | 4 |
| Liu, X | 1 |
| Yeh, JK | 4 |
| Matsumoto, Y | 1 |
| Mikuni-Takagaki, Y | 1 |
| Kozai, Y | 1 |
| Miyagawa, K | 1 |
| Naruse, K | 1 |
| Wakao, H | 1 |
| Kawamata, R | 1 |
| Kashima, I | 1 |
| Sakurai, T | 1 |
| Fujita, Y | 1 |
| Watanabe, K | 1 |
| Uchikanbori, S | 1 |
| Maki, K | 1 |
| Sugiyama, T | 1 |
| Meakin, LB | 1 |
| Galea, GL | 1 |
| Jackson, BF | 1 |
| Lanyon, LE | 1 |
| Ebetino, FH | 1 |
| Russell, RG | 2 |
| Price, JS | 1 |
| Iguchi, M | 1 |
| Erben, RG | 1 |
| Mosekilde, L | 2 |
| Thomsen, JS | 2 |
| Weber, K | 1 |
| Stahr, K | 1 |
| Leyshon, A | 1 |
| Smith, SY | 1 |
| Phipps, R | 1 |
| Ichimura, S | 2 |
| Nishida, A | 1 |
| Ito, M | 2 |
| Uetani, M | 1 |
| Nakayama, T | 1 |
| Tanaka, T | 2 |
| Otomo, H | 1 |
| Sakai, A | 1 |
| Ikeda, S | 1 |
| Tanaka, S | 1 |
| Phipps, RJ | 3 |
| Nakamura, T | 1 |
| Olszynski, WP | 1 |
| Davison, KS | 1 |
| Ioannidis, G | 1 |
| Brown, JP | 1 |
| Hanley, DA | 1 |
| Josse, RG | 1 |
| Murray, TM | 1 |
| Papaioannou, A | 1 |
| Sebaldt, RJ | 1 |
| Tenenhouse, AM | 1 |
| Petrie, A | 1 |
| Goldsmith, CH | 1 |
| Adachi, JD | 1 |
| Tamura, K | 1 |
| Suzuki, Y | 1 |
| Hashiba, H | 1 |
| Tamura, H | 1 |
| Aizawa, S | 1 |
| Kogo, H | 1 |
| Seki, A | 2 |
| Yamada, H | 2 |
| Shen, CL | 2 |
| Fuchs, RK | 1 |
| Burr, DB | 2 |
| Larsson, SE | 1 |
| Ahlgren, O | 1 |
| Jee, WS | 3 |
| Lin, BY | 1 |
| Ma, YF | 1 |
| Ke, HZ | 3 |
| Zhu, BQ | 1 |
| Sun, YP | 1 |
| Sievers, RE | 1 |
| Isenberg, WM | 1 |
| Moorehead, TJ | 1 |
| Parmley, WW | 1 |
| Hall, DG | 1 |
| Stoica, G | 1 |
| Ma, Y | 1 |
| Chen, YY | 1 |
| Ijiri, K | 1 |
| Iwase, T | 1 |
| Hasegawa, Y | 1 |
| Ito, T | 1 |
| Makihara, N | 1 |
| Takahashi, H | 1 |
| Iwata, H | 1 |
| Patel, R | 2 |
| Blake, GM | 2 |
| Herd, RJ | 2 |
| Fogelman, I | 2 |
| Azuma, Y | 1 |
| Oue, Y | 1 |
| Kanatani, H | 1 |
| Ohta, T | 1 |
| Kiyoki, M | 1 |
| Komoriya, K | 1 |
| Mackey, MS | 1 |
| Nishikawa, T | 1 |
| Ogawa, S | 1 |
| Kogita, K | 1 |
| Manabe, N | 1 |
| Katsumata, T | 2 |
| Nakamura, K | 1 |
| Kawaguchi, H | 1 |
| Mashiba, T | 1 |
| Turner, CH | 1 |
| Hirano, T | 1 |
| Forwood, MR | 1 |
| Jacob, DS | 1 |
| Johnston, CC | 1 |
| Toyama, Y | 1 |
| Libouban, H | 1 |
| Moreau, MF | 1 |
| Legrand, E | 1 |
| Baslé, MF | 1 |
| Audran, M | 1 |
| Chappard, D | 1 |
| Pointon, JJ | 1 |
| Francis, MJ | 1 |
| Smith, R | 1 |
| Flora, L | 1 |
| Goulding, A | 1 |
| McChesney, R | 1 |
| Malthus, RS | 1 |
| Chan, MM | 1 |
| Rucker, RB | 1 |
| Riggins, RS | 1 |
| Trechsel, U | 1 |
| Schenk, R | 1 |
| Bonjour, JP | 1 |
| Fleisch, H | 1 |
| Tang, LY | 1 |
| Kimmel, DB | 1 |
| Grigoriev, AI | 1 |
| Morukov, BV | 1 |
| Oganov, VS | 1 |
| Rakhmanov, AS | 1 |
| Buravkova, LB | 1 |
| Togari, A | 1 |
| Arai, M | 1 |
| Hironaka, M | 1 |
| Matsumoto, S | 1 |
| Shinoda, H | 1 |
| Izumi, T | 1 |
| Rowe, DJ | 1 |
| Sakiyama, Y | 1 |
| Tada, I | 1 |
| Yamamoto, H | 1 |
| Nakanishi, T | 1 |
| Yasuda, Y | 1 |
| Soeda, Y | 1 |
| Oda, M | 1 |
| Shiota, E | 1 |
| Recker, RR | 1 |
| Saville, PD | 1 |
| Lane, JM | 1 |
| Steinberg, ME | 1 |
| Bar, A | 1 |
| Hurwitz, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Neoadjuvant Chemotherapy With or Without Zometa on Occult Micrometastases and Bone Density in Women With Locally Advanced Breast Cancer[NCT00242203] | Phase 2 | 120 participants (Actual) | Interventional | 2002-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for etidronate and Body Weight
| Article | Year |
|---|---|
The effect of weight change on DXA scans in a 2-year trial of etidronate therapy.
Topics: Absorptiometry, Photon; Aged; Algorithms; Body Weight; Bone Density; Double-Blind Method; Etidronic | 1997 |
The effect of weight change on total body dual-energy X-ray absorptiometry: results from a clinical trial.
Topics: Absorptiometry, Photon; Aged; Body Weight; Bone Density; Double-Blind Method; Etidronic Acid; Female | 2000 |
42 other studies available for etidronate and Body Weight
| Article | Year |
|---|---|
Effects of vitamin K(2) and risedronate on bone formation and resorption, osteocyte lacunar system, and porosity in the cortical bone of glucocorticoid-treated rats.
Topics: Animals; Body Weight; Bone Density Conservation Agents; Bone Resorption; Disease Models, Animal; Dru | 2008 |
Prior treatment with vitamin K(2) significantly improves the efficacy of risedronate.
Topics: Animals; Body Weight; Bone Density Conservation Agents; Drug Administration Schedule; Drug Evaluatio | 2009 |
Effects of risedronate on cortical and trabecular bone of the mandible in glucocorticoid-treated growing rats.
Topics: Anatomy, Cross-Sectional; Animals; Body Weight; Bone Density; Bone Density Conservation Agents; Etid | 2011 |
Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice.
Topics: Animals; Body Weight; Bone and Bones; Etidronic Acid; Female; Fluorescent Dyes; Mice; Mice, Inbred C | 2011 |
Effects of etidronate on calcification of scales and ribs in the goldfish, Carassius auratus.
Topics: Animals; Body Weight; Calcification, Physiologic; Calcium; Etidronic Acid; Goldfish; Regeneration; R | 2012 |
Prevention of bone loss in ovariectomized rats by combined treatment with risedronate and 1alpha,25-dihydroxyvitamin D3.
Topics: Animals; Biomechanical Phenomena; Body Weight; Bone Density; Calcitriol; Etidronic Acid; Female; Ost | 2002 |
Differential effect of short-term etidronate treatment on three cancellous bone sites in orchidectomized adult rats.
Topics: Animals; Body Weight; Bone and Bones; Etidronic Acid; Lumbar Vertebrae; Male; Orchiectomy; Rats; Rat | 2004 |
Effect of etidronate on three-dimensional trabecular structure in ovariectomized or sciatic neurectomized rats.
Topics: Animals; Body Weight; Etidronic Acid; Female; Ovariectomy; Rats; Rats, Inbred Lew; Tibia; Tomography | 2004 |
Regulation of mineral-to-matrix ratio of lumbar trabecular bone in ovariectomized rats treated with risedronate in combination with or without vitamin K2.
Topics: Absorptiometry, Photon; Amino Acids; Animals; Biomechanical Phenomena; Body Weight; Bone Density; Bo | 2004 |
Effectiveness of alendronate and etidronate in the treatment of osteoporosis in men: a prospective observational study.
Topics: Alendronate; Body Height; Body Weight; Bone Density; Bone Density Conservation Agents; Etidronic Aci | 2006 |
Effect of etidronate on aortic calcification and bone metabolism in calcitriol-treated rats with subtotal nephrectomy.
Topics: Amino Acids; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Body Weight; Bone and Bone | 2005 |
Comparative effects of risedronate and calcitriol on cancellous bone in rats with glucocorticoid-induced osteopenia.
Topics: Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; Bone Diseases, Metaboli | 2006 |
Beneficial effect of pretreatment and treatment continuation with risedronate and vitamin K2 on cancellous bone loss after ovariectomy in rats: a bone histomorphometry study.
Topics: Absorptiometry, Photon; Analysis of Variance; Animals; Body Weight; Bone Density; Bone Density Conse | 2006 |
Effect of risedronate on the cortical and cancellous bone mass and mechanical properties in ovariectomized rats: a comparison with the effects of alfacalcidol.
Topics: Analysis of Variance; Animals; Body Weight; Bone Density; Bone Density Conservation Agents; Bone Res | 2006 |
Recovery of trabecular and cortical bone turnover after discontinuation of risedronate and alendronate therapy in ovariectomized rats.
Topics: Alendronate; Animals; Body Weight; Bone Density; Bone Density Conservation Agents; Bone Remodeling; | 2008 |
Effects of disodium ethane-1-hydroxy-1, 1-diphosphonate (EHDP) in adult normal and selectively parathyroidectomized rats. I. Effects on plasma calcium, bone tissue, and adrenal glands at low or normal calcium intake.
Topics: Adrenal Glands; Animals; Body Weight; Bone and Bones; Calcium; Calcium, Dietary; Etidronic Acid; Mal | 1982 |
Extra cancellous bone induced by combined prostaglandin E2 and risedronate administration is maintained after their withdrawal in older female rats.
Topics: Aging; Analysis of Variance; Animals; Body Weight; Bone Development; Bone Resorption; Calcium Channe | 1995 |
Effects of etidronate and lovastatin on the regression of atherosclerosis in cholesterol-fed rabbits.
Topics: Animals; Aortic Diseases; Arteriosclerosis; Body Weight; Bone and Bones; Calcium; Diet, Atherogenic; | 1994 |
Effect of the bisphosphonate risedronate on bone metastases in a rat mammary adenocarcinoma model system.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Body Weight; Bone and Bones; Bone Neoplasms; Bone Res | 1994 |
Co-treatment of PGE2 and risedronate is better than PGE2 alone in the long-term treatment of ovariectomized-induced osteopenic rats.
Topics: Aging; Animals; Body Weight; Bone Development; Bone Diseases, Metabolic; Dinoprostone; Drug Therapy, | 1995 |
Bone composition and metabolism after hyperbaric oxygenation in rats with 1-hydroxyethylidene-1,1-bisphosphonate-induced rickets.
Topics: Animals; Body Weight; Bone and Bones; Calcification, Physiologic; Calcium; Etidronic Acid; Hydroxypr | 1996 |
Effects of continuous alendronate treatment on bone mass and mechanical properties in ovariectomized rats: comparison with pamidronate and etidronate in growing rats.
Topics: Alendronate; Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; Diphosphon | 1998 |
Treatment with risedronate or alendronate prevents hind-limb immobilization-induced loss of bone density and strength in adult female rats.
Topics: Alendronate; Animals; Body Weight; Etidronic Acid; Female; Femur; Hindlimb Suspension; Osteoporosis; | 2000 |
Additive effects of combined treatment with etidronate and alfacalcidol on bone mass and mechanical properties in ovariectomized rats.
Topics: Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Bone Density; Etidronic Acid; Female; | 2000 |
Effects of high-dose etidronate treatment on microdamage accumulation and biomechanical properties in beagle bone before occurrence of spontaneous fractures.
Topics: Animals; Biomechanical Phenomena; Body Weight; Bone Density; Bone Remodeling; Disease Models, Animal | 2001 |
Effect of etidronate on bone in orchidectomized and sciatic neurectomized adult rats.
Topics: Age Factors; Amino Acids; Animals; Body Weight; Bone Density; Bone Resorption; Denervation; Etidroni | 2002 |
Comparison insight dual X-ray absorptiometry (DXA), histomorphometry, ash weight, and morphometric indices for bone evaluation in an animal model (the orchidectomized rat) of male osteoporosis.
Topics: Absorptiometry, Photon; Animals; Body Weight; Bone and Bones; Bone Density; Climacteric; Disease Mod | 2001 |
Effect of vitamin D deficiency on sarcoplasmic reticulum function and troponin C concentration of rabbit skeletal muscle.
Topics: Animals; Body Weight; Bone and Bones; Calcium; Etidronic Acid; Male; Muscle Proteins; Muscles; Phosp | 1979 |
Comparative antiinflammatory and bone protective effects of two diphosphonates in adjuvant arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Body Weight; Bone and Bones; | 1979 |
Diminished urinary excretion of cycle AMP by rats given disodium ethane-1-hydroxy-1,1-diphosphonate.
Topics: Animals; Body Weight; Calcium; Cyclic AMP; Depression, Chemical; Etidronic Acid; Male; Organophospho | 1975 |
Effects of fluoride and ethane-1-hydroxy-1,1-diphosphonate on bone metabolism in the growing chick.
Topics: Alkaline Phosphatase; Animals; Apatites; Body Weight; Bone and Bones; Calcium; Chick Embryo; Cyclic | 1976 |
Relation between bone mineralization, Ca absorption, and plasma Ca in phosphonate-treated rats.
Topics: Animals; Apatites; Body Weight; Bone and Bones; Calcium; Chemical Phenomena; Chemistry; Crystallizat | 1977 |
Restoring and maintaining bone in osteopenic female rat skeleton: I. Changes in bone mass and structure.
Topics: Aging; Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Bone Resorption | 1992 |
Effect of exercise and bisphosphonate on mineral balance and bone density during 360 day antiorthostatic hypokinesia.
Topics: Adult; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Calcium; Combined Modality Therap | 1992 |
Effect of HEBP (1-hydroxyethylidene-1,1-bisphosphonate) on experimental osteoporosis induced by ovariectomy in rats.
Topics: Animals; Body Weight; Calcification, Physiologic; Calcium; Disease Models, Animal; Drug Administrati | 1991 |
[Effects of 1-hydroxyethylidene-1, 1-bisphosphonate (HEBP) on the unimpeded eruption rate and the dental hard tissue formation in rat mandibular incisor].
Topics: Animals; Body Weight; Depression, Chemical; Diphosphonates; Etidronic Acid; Incisor; Injections, Sub | 1989 |
Effects of a fluorinated bisphosphonate on bone remodeling in vivo.
Topics: Animals; Body Weight; Bone and Bones; Bone Development; Calcium; Clodronic Acid; Diphosphonates; Eti | 1985 |
The effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) on fetal mice during pregnancy--with emphasis on implantation and fetal weight.
Topics: Animals; Body Weight; Embryo Implantation; Etidronic Acid; Female; Fetal Viability; Fetus; Male; Mic | 1986 |
Effects of diphosphonate on osteoporosis induced in rats. Roentogenological, histological and biomechanical studies.
Topics: Animals; Body Weight; Bone and Bones; Calcium, Dietary; Castration; Denervation; Drug Administration | 1985 |
Intestinal absorption of disodium ethane-1-hydroxy-1,1-diphosphonate (disodium etidronate) using a deconvolution technique.
Topics: Administration, Oral; Adult; Body Weight; Carbon Isotopes; Etidronic Acid; Feces; Humans; Injections | 1973 |
The role of diphosphonates in osteoporosis of disuse.
Topics: Animals; Body Weight; Bone and Bones; Calcitonin; Calcium; Calcium Radioisotopes; Etidronic Acid; Fe | 1973 |
Bone ash and duodenal calcium-binding protein in chicks treated with EHDP.
Topics: Animal Feed; Animals; Body Weight; Bone and Bones; Calcium; Chickens; Duodenum; Etidronic Acid; Inje | 1973 |