etidronate has been researched along with Autosomal Dominant Cerebellar Ataxia, Type II in 1 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, G | 1 |
| Nakayama, L | 1 |
| Blum, JA | 1 |
| Akiyama, T | 1 |
| Boeynaems, S | 1 |
| Chakraborty, M | 1 |
| Couthouis, J | 1 |
| Tassoni-Tsuchida, E | 1 |
| Rodriguez, CM | 1 |
| Bassik, MC | 1 |
| Gitler, AD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1/2 Multiple-Ascending-Dose Study With a Long-Term Open-Label Extension to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Effect on Disease Progression of BIIB105 Administered Intrathecally to Adults With Amyotrophic Late[NCT04494256] | Phase 1/Phase 2 | 99 participants (Actual) | Interventional | 2020-09-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for etidronate and Autosomal Dominant Cerebellar Ataxia, Type II
| Article | Year |
|---|---|
Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2.
Topics: Amyotrophic Lateral Sclerosis; Animals; Ataxin-2; Etidronic Acid; Humans; Mice; Oligonucleotides, An | 2022 |