Page last updated: 2024-10-26

etidronate and Atheroma

etidronate has been researched along with Atheroma in 6 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Research Excerpts

ExcerptRelevanceReference
"Eighty-seven patients with hypercholesterolemia were assigned to the atorvastatin (ATR)+etidronate (ETD) group (n = 45) or ATR group (n = 42)."3.77Effect of atorvastatin and etidronate combination therapy on regression of aortic atherosclerotic plaques evaluated by magnetic resonance imaging. ( Furusawa, T; Inazu, T; Kawahara, T; Nishikawa, M; Suzuki, G, 2011)
"Statins are not effective in reducing atherosclerotic plaques of the abdominal aorta, and accumulating evidence suggests that bisphosphonates have the potential to induce the regression of atherosclerotic plaques of the abdominal aorta."2.78Atorvastatin, etidronate, or both in patients at high risk for atherosclerotic aortic plaques: a randomized, controlled trial. ( Inazu, T; Kawahara, C; Kawahara, T; Nishikawa, M; Sakai, K; Suzuki, G, 2013)
"Vascular calcification is an active process in which vascular smooth muscle cells (VSMCs) adopt an osteoblastic phenotype and deposit hydroxyapatite crystals; apoptosis of VSMCs also promotes this deposition."2.50The molecular biology and pathophysiology of vascular calcification. ( DiNicolantonio, JJ; McCarty, MF, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawahara, T3
Nishikawa, M2
Kawahara, C1
Inazu, T2
Sakai, K1
Suzuki, G3
King, A1
McCarty, MF1
DiNicolantonio, JJ1
Scharlach, C1
Kratz, H1
Wiekhorst, F1
Warmuth, C1
Schnorr, J1
Genter, G1
Ebert, M1
Mueller, S1
Schellenberger, E1
Furusawa, T1

Reviews

1 review available for etidronate and Atheroma

ArticleYear
The molecular biology and pathophysiology of vascular calcification.
    Postgraduate medicine, 2014, Volume: 126, Issue:2

    Topics: Antioxidants; Biomarkers; Bone Density Conservation Agents; Etidronic Acid; Humans; Magnesium; Muscl

2014

Trials

2 trials available for etidronate and Atheroma

ArticleYear
Atorvastatin, etidronate, or both in patients at high risk for atherosclerotic aortic plaques: a randomized, controlled trial.
    Circulation, 2013, Jun-11, Volume: 127, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Atorvastatin; Bo

2013
[Series: Clinical study from Japan and its reflections; atorvastatin, etidronate, or both in patients at high risk for atherosclerotic aortic plaques: a randomized, controlled trial].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2014, Feb-10, Volume: 103, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aorta; Atorvastatin; Drug Therapy, Combination; Etidronic Acid; Fema

2014

Other Studies

3 other studies available for etidronate and Atheroma

ArticleYear
Vascular disease: aortic plaque--dual therapy for a heterogeneous disease.
    Nature reviews. Cardiology, 2013, Volume: 10, Issue:7

    Topics: Aortic Diseases; Calcinosis; Etidronic Acid; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-

2013
Synthesis of acid-stabilized iron oxide nanoparticles and comparison for targeting atherosclerotic plaques: evaluation by MRI, quantitative MPS, and TEM alternative to ambiguous Prussian blue iron staining.
    Nanomedicine : nanotechnology, biology, and medicine, 2015, Volume: 11, Issue:5

    Topics: Animals; Aorta; Apolipoproteins E; Carotid Arteries; Citric Acid; Etidronic Acid; Ferric Compounds;

2015
Effect of atorvastatin and etidronate combination therapy on regression of aortic atherosclerotic plaques evaluated by magnetic resonance imaging.
    Journal of atherosclerosis and thrombosis, 2011, Volume: 18, Issue:5

    Topics: Aorta; Atorvastatin; Bone Density Conservation Agents; Drug Therapy, Combination; Etidronic Acid; Fe

2011