Page last updated: 2024-10-26

etidronate and Asthma

etidronate has been researched along with Asthma in 8 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"The study was designed to establish the effects of HRT on osteoporosis and fractures over five years in postmenopausal women with asthma receiving regular glucocorticoids and to compare with etidronate."9.14Hormone replacement therapy (HRT) or etidronate for osteoporosis in postmenopausal asthmatics on glucocorticoids: a randomised factorial trial. ( Campbell, IA; Douglas, JG; Francis, RM; Prescott, RJ; Reid, DM, 2009)
" A randomised study was performed to determine whether treatment with cyclical etidronate and/or calcium for 5 years prevents fractures or reverses/reduces bone loss in patients receiving glucocorticoid treatment for asthma."9.11Five year study of etidronate and/or calcium as prevention and treatment for osteoporosis and fractures in patients with asthma receiving long term oral and/or inhaled glucocorticoids. ( Campbell, IA; Douglas, JG; Francis, RM; Prescott, RJ; Reid, DM, 2004)
"The study was designed to establish the effects of HRT on osteoporosis and fractures over five years in postmenopausal women with asthma receiving regular glucocorticoids and to compare with etidronate."5.14Hormone replacement therapy (HRT) or etidronate for osteoporosis in postmenopausal asthmatics on glucocorticoids: a randomised factorial trial. ( Campbell, IA; Douglas, JG; Francis, RM; Prescott, RJ; Reid, DM, 2009)
" A randomised study was performed to determine whether treatment with cyclical etidronate and/or calcium for 5 years prevents fractures or reverses/reduces bone loss in patients receiving glucocorticoid treatment for asthma."5.11Five year study of etidronate and/or calcium as prevention and treatment for osteoporosis and fractures in patients with asthma receiving long term oral and/or inhaled glucocorticoids. ( Campbell, IA; Douglas, JG; Francis, RM; Prescott, RJ; Reid, DM, 2004)
"The results show that intermittent cyclical etidronate therapy with calcium and vitamin D supplementation significantly increases lumbar spine BMD in patients with osteoporosis resulting from long-term treatment with corticosteroids."5.08A double blind placebo controlled study to determine the effects of intermittent cyclical etidronate on bone mineral density in patients on long-term oral corticosteroid treatment. ( Li, F; Moniz, C; Pack, S; Pitt, P; Todd, P; Webber, D, 1998)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, IA2
Douglas, JG2
Francis, RM2
Prescott, RJ2
Reid, DM2
Ortego-Centeno, N1
Muñoz-Torres, M1
Callejas-Rubio, JL1
Riera-Montes, M1
Rolla, G1
Bucca, C1
Brussino, L1
Worth, H1
Stammen, D1
Keck, E1
Pitt, P1
Li, F1
Todd, P1
Webber, D1
Pack, S1
Moniz, C1
Goldstein, MF1
Fallon, JJ1
Harning, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
HRT and/or Etidronate in the Prevention and Treatment of Osteoporosis and Fractures in Post-Menopausal Patients With Asthma Receiving Long-Term Oral and/or Inhaled Glucocorticoids:a Randomised Factorial Trial[NCT00376662]Phase 4750 participants Interventional1992-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for etidronate and Asthma

ArticleYear
Chronic glucocorticoid therapy-induced osteoporosis in patients with obstructive lung disease.
    Chest, 1999, Volume: 116, Issue:6

    Topics: Administration, Inhalation; Administration, Oral; Adult; Alendronate; Asthma; Bone Density; Bone Rem

1999

Trials

5 trials available for etidronate and Asthma

ArticleYear
Hormone replacement therapy (HRT) or etidronate for osteoporosis in postmenopausal asthmatics on glucocorticoids: a randomised factorial trial.
    Scottish medical journal, 2009, Volume: 54, Issue:1

    Topics: Anti-Asthmatic Agents; Asthma; Bone Density Conservation Agents; Cohort Studies; Estrogen Replacemen

2009
Five year study of etidronate and/or calcium as prevention and treatment for osteoporosis and fractures in patients with asthma receiving long term oral and/or inhaled glucocorticoids.
    Thorax, 2004, Volume: 59, Issue:9

    Topics: Administration, Inhalation; Administration, Oral; Asthma; Bone Density; Calcium; Etidronic Acid; Fem

2004
Etidronate and glucocorticoid induced osteoporosis.
    The Journal of rheumatology, 2005, Volume: 32, Issue:1

    Topics: Asthma; Bone Density; Budesonide; Drug Therapy, Combination; Etidronic Acid; Glucocorticoids; Humans

2005
Therapy of steroid-induced bone loss in adult asthmatics with calcium, vitamin D, and a diphosphonate.
    American journal of respiratory and critical care medicine, 1994, Volume: 150, Issue:2

    Topics: Adrenal Cortex Hormones; Asthma; Bone Density; Calcium; Drug Therapy, Combination; Etidronic Acid; F

1994
A double blind placebo controlled study to determine the effects of intermittent cyclical etidronate on bone mineral density in patients on long-term oral corticosteroid treatment.
    Thorax, 1998, Volume: 53, Issue:5

    Topics: Aged; Asthma; Bone Density; Calcium; Double-Blind Method; Drug Therapy, Combination; Etidronic Acid;

1998

Other Studies

2 other studies available for etidronate and Asthma

ArticleYear
[Asthma--prevention of glucocorticoid-induced osteoporosis with etidronate and calcium].
    Pneumologie (Stuttgart, Germany), 2005, Volume: 59, Issue:2

    Topics: Asthma; Calcium; Etidronic Acid; Glucocorticoids; Humans; Osteoporosis

2005
Bisphosphonate-induced bronchoconstriction in aspirin-sensitive asthma.
    Lancet (London, England), 1994, Feb-12, Volume: 343, Issue:8894

    Topics: Aspirin; Asthma; Clodronic Acid; Etidronic Acid; Female; Humans; Middle Aged

1994