etidronate has been researched along with Arthritis, Rheumatoid in 26 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of vitamin K2 (Vit K2) alone or in combination with etidronate and risedronate on bone loss, osteoclast induction, and inflammation in patients with rheumatoid arthritis (RA)." | 9.13 | Osteoclast inhibitory effects of vitamin K2 alone or in combination with etidronate or risedronate in patients with rheumatoid arthritis: 2-year results. ( Morishita, M; Nagashima, M; Takahashi, H; Takenouchi, K; Wauke, K, 2008) |
| "To investigate the effect of intermittent cyclical etidronate treatment on radiographic progression, bone collagen markers, and clinical disease activity in patients with rheumatoid arthritis (RA)." | 9.10 | Two year randomized controlled trial of etidronate in rheumatoid arthritis: changes in serum aminoterminal telopeptides correlate with radiographic progression of disease. ( Friman, C; Koivula, MK; Konttinen, YT; Laasonen, L; Mandelin, J; Risteli, J; Valleala, H, 2003) |
| "To evaluate the role of serum osteoprotegerin (OPG) as a biochemical marker for disease activity assessment and drug monitoring in patients with rheumatoid arthritis (RA) treated with cyclical etidronate." | 9.10 | Effect of cyclical intermittent etidronate therapy on circulating osteoprotegerin levels in patients with rheumatoid arthritis. ( Koivula, MK; Konttinen, YT; Laasonen, L; Mandelin, J; Risteli, J; Valleala, H, 2003) |
| " We have evaluated etidronate disodium, a diphosphonate commonly prescribed in the United Kingdom for Paget's disease in patients with rheumatoid arthritis." | 9.06 | A clinical and biochemical assessment of etidronate disodium in patients with active rheumatoid arthritis. ( Bird, HA; Dixon, JS; Hill, J; Sitton, NG; Wright, V, 1988) |
| "This study was conducted to identify bone resorption and anti-inflammatory effects with intermittent cyclical etidronate therapy (ICET) in patients with rheumatoid arthritis, and anti-inflammatory effect of etidronate in vitro." | 7.73 | Inhibitory effect of bone resorption and inflammation with etidronate therapy in patients with rheumatoid arthritis for 3 years and in vitro assay in arthritis models. ( Nagashima, M; Shue, G; Yamamoto, K; Yoshino, S, 2006) |
| "Etidronate was effective at inhibiting bone resorption and destruction in study patients with RA, while not increasing BAP concentrations; and a correlation was observed between the concentration of DPD and IL-6, indicating the antiinflammatory effect of etidronate." | 6.71 | Bone resorption and inflammatory inhibition efficacy of intermittent cyclical etidronate therapy in rheumatoid arthritis. ( Hasegawa, J; Katsumata, S; Nagashima, M; Nishijima, T; Yamamoto, M; Yoshino, S, 2003) |
| "Kynurenine analysis was performed by HPLC." | 5.32 | Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment. ( Darlington, LG; Forrest, CM; Kennedy, A; Stone, TW; Stoy, N, 2003) |
| "To investigate the effects of vitamin K2 (Vit K2) alone or in combination with etidronate and risedronate on bone loss, osteoclast induction, and inflammation in patients with rheumatoid arthritis (RA)." | 5.13 | Osteoclast inhibitory effects of vitamin K2 alone or in combination with etidronate or risedronate in patients with rheumatoid arthritis: 2-year results. ( Morishita, M; Nagashima, M; Takahashi, H; Takenouchi, K; Wauke, K, 2008) |
| "To investigate the effect of intermittent cyclical etidronate treatment on radiographic progression, bone collagen markers, and clinical disease activity in patients with rheumatoid arthritis (RA)." | 5.10 | Two year randomized controlled trial of etidronate in rheumatoid arthritis: changes in serum aminoterminal telopeptides correlate with radiographic progression of disease. ( Friman, C; Koivula, MK; Konttinen, YT; Laasonen, L; Mandelin, J; Risteli, J; Valleala, H, 2003) |
| "To evaluate the role of serum osteoprotegerin (OPG) as a biochemical marker for disease activity assessment and drug monitoring in patients with rheumatoid arthritis (RA) treated with cyclical etidronate." | 5.10 | Effect of cyclical intermittent etidronate therapy on circulating osteoprotegerin levels in patients with rheumatoid arthritis. ( Koivula, MK; Konttinen, YT; Laasonen, L; Mandelin, J; Risteli, J; Valleala, H, 2003) |
| " We used a randomized placebo-controlled design to evaluate the efficacy of one-year cyclical etidronate therapy in preventing bone loss in 83 glucocorticoid-treated patients with rheumatoid arthritis, polymyalgia rheumatica, or giant cell arteritis." | 5.09 | Evaluation of the efficacy of etidronate therapy in preventing glucocorticoid-induced bone loss in patients with inflammatory rheumatic diseases. A randomized study. ( Barton, I; Bonvoisin, B; Cortet, B; Hachulla, E; Roux, C, 1999) |
| "A double blind, randomised placebo controlled study comparing cyclic etidronate and placebo during two years in 37 postmenopausal women receiving long term corticosteroid treatment, mainly for polymyalgia rheumatica (40% of the patients) and rheumatoid arthritis (30%)." | 5.08 | Cyclical etidronate increases bone density in the spine and hip of postmenopausal women receiving long term corticosteroid treatment. A double blind, randomised placebo controlled study. ( Boonen, S; Dequeker, J; Geusens, P; Joly, J; Nijs, J; Raus, J; Stalmans, R; Vanhoof, J, 1998) |
| "Cohort study in a tertiary care university affiliated hospital in corticosteroid treated patients, with polymyalgia rheumatica, asthma, systemic lupus erythematosus, rheumatoid arthritis, or temporal arteritis, examining the effects of ICT etidronate." | 5.07 | Intermittent cyclic therapy with etidronate in the prevention of corticosteroid induced bone loss. ( Adachi, J; Bensen, WG; Bianchi, F; Cividino, A; Craig, GL; Cranney, A; Goldsmith, CH; Kaminska, E; Papaioannou, A; Sebaldt, RJ, 1994) |
| " We have evaluated etidronate disodium, a diphosphonate commonly prescribed in the United Kingdom for Paget's disease in patients with rheumatoid arthritis." | 5.06 | A clinical and biochemical assessment of etidronate disodium in patients with active rheumatoid arthritis. ( Bird, HA; Dixon, JS; Hill, J; Sitton, NG; Wright, V, 1988) |
| "This study was conducted to identify bone resorption and anti-inflammatory effects with intermittent cyclical etidronate therapy (ICET) in patients with rheumatoid arthritis, and anti-inflammatory effect of etidronate in vitro." | 3.73 | Inhibitory effect of bone resorption and inflammation with etidronate therapy in patients with rheumatoid arthritis for 3 years and in vitro assay in arthritis models. ( Nagashima, M; Shue, G; Yamamoto, K; Yoshino, S, 2006) |
| "Osteoporosis is a common adverse reaction induced by glucocorticoid treatment." | 2.73 | Comparative studies on effect of risedronate and alfacalcidol against glucocorticoid-induced osteoporosis in rheumatoid arthritic patients. ( Ichimura, A; Iwata, H; Nakajima, T; Ochiai, H; Takagi, H; Toriyama, T; Tsuchiya, H; Yamada, S, 2007) |
| "Etidronate was effective at inhibiting bone resorption and destruction in study patients with RA, while not increasing BAP concentrations; and a correlation was observed between the concentration of DPD and IL-6, indicating the antiinflammatory effect of etidronate." | 2.71 | Bone resorption and inflammatory inhibition efficacy of intermittent cyclical etidronate therapy in rheumatoid arthritis. ( Hasegawa, J; Katsumata, S; Nagashima, M; Nishijima, T; Yamamoto, M; Yoshino, S, 2003) |
| "Breast or prostate cancer patients were treated with zoledronate." | 1.39 | Bisphosphonate-related osteonecrosis of jaw (BRONJ) in Japanese population: a case series of 13 patients at our clinic. ( Fujimoto, Y; Muramatsu, K; Murayama, M; Nakata, E; Nomura, T; Ogane, S; Sekine, R; Shibahara, T; Shibui, T; Uchiyama, T; Watanabe, A; Yakushiji, T; Yamamoto, N, 2013) |
| "Kynurenine analysis was performed by HPLC." | 1.32 | Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment. ( Darlington, LG; Forrest, CM; Kennedy, A; Stone, TW; Stoy, N, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 14 (53.85) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nomura, T | 1 |
| Shibahara, T | 1 |
| Uchiyama, T | 1 |
| Yamamoto, N | 1 |
| Shibui, T | 1 |
| Yakushiji, T | 1 |
| Watanabe, A | 1 |
| Muramatsu, K | 1 |
| Ogane, S | 1 |
| Murayama, M | 1 |
| Sekine, R | 1 |
| Nakata, E | 1 |
| Fujimoto, Y | 1 |
| Laurent, AJ | 1 |
| Bindslev, N | 1 |
| Johansson, B | 1 |
| Berg, L | 1 |
| Valleala, H | 2 |
| Laasonen, L | 2 |
| Koivula, MK | 2 |
| Mandelin, J | 2 |
| Friman, C | 1 |
| Risteli, J | 2 |
| Konttinen, YT | 2 |
| Hasegawa, J | 1 |
| Nagashima, M | 3 |
| Yamamoto, M | 1 |
| Nishijima, T | 1 |
| Katsumata, S | 1 |
| Yoshino, S | 2 |
| Forrest, CM | 1 |
| Kennedy, A | 1 |
| Stone, TW | 1 |
| Stoy, N | 1 |
| Darlington, LG | 1 |
| Lange, U | 1 |
| Illgner, U | 1 |
| Teichmann, J | 1 |
| Schleenbecker, H | 1 |
| Yamamoto, K | 1 |
| Shue, G | 1 |
| Cruse, LM | 1 |
| Valeriano, J | 1 |
| Vasey, FB | 1 |
| Carter, JD | 1 |
| Yamada, S | 1 |
| Takagi, H | 1 |
| Tsuchiya, H | 1 |
| Nakajima, T | 1 |
| Ochiai, H | 1 |
| Ichimura, A | 1 |
| Iwata, H | 1 |
| Toriyama, T | 1 |
| Nakayama, H | 1 |
| Morishita, M | 1 |
| Wauke, K | 1 |
| Takahashi, H | 1 |
| Takenouchi, K | 1 |
| Katayama, K | 1 |
| Matsuno, T | 1 |
| Oh, BK | 1 |
| Macfarlane, JD | 1 |
| Goei The, HS | 1 |
| Pauwels, EK | 1 |
| Bijvoet, OL | 1 |
| Frijlink, WB | 1 |
| Jie, K | 1 |
| van der Linden, H | 1 |
| Meijer, CJ | 1 |
| Mulder, H | 1 |
| van Paassen, HC | 1 |
| Reitsma, PH | 1 |
| te Velde, J | 1 |
| de Vries, E | 1 |
| van der Wey, JP | 1 |
| Adachi, J | 1 |
| Cranney, A | 1 |
| Goldsmith, CH | 1 |
| Bensen, WG | 1 |
| Bianchi, F | 1 |
| Cividino, A | 1 |
| Craig, GL | 1 |
| Kaminska, E | 1 |
| Sebaldt, RJ | 1 |
| Papaioannou, A | 1 |
| Disla, E | 1 |
| Tamayo, B | 1 |
| Fahmy, A | 1 |
| Geusens, P | 1 |
| Dequeker, J | 1 |
| Vanhoof, J | 1 |
| Stalmans, R | 1 |
| Boonen, S | 1 |
| Joly, J | 1 |
| Nijs, J | 1 |
| Raus, J | 1 |
| Cortet, B | 1 |
| Hachulla, E | 1 |
| Barton, I | 1 |
| Bonvoisin, B | 1 |
| Roux, C | 1 |
| Jenkins, EA | 1 |
| Walker-Bone, KE | 1 |
| Wood, A | 1 |
| McCrae, FC | 1 |
| Cooper, C | 1 |
| Cawley, MI | 1 |
| Eastell, R | 1 |
| Devogelaer, JP | 1 |
| Peel, NF | 1 |
| Chines, AA | 1 |
| Bax, DE | 1 |
| Sacco-Gibson, N | 1 |
| Nagant de Deuxchaisnes, C | 1 |
| Russell, RG | 1 |
| Solomon, DH | 1 |
| Kuntz, KM | 1 |
| Palmedo, H | 1 |
| Rockstroh, JK | 1 |
| Bangard, M | 1 |
| Schliefer, K | 1 |
| Risse, J | 1 |
| Menzel, C | 1 |
| Biersack, HJ | 1 |
| Halverson, PB | 1 |
| McCarty, DJ | 1 |
| Park, HM | 1 |
| Terman, SA | 1 |
| Ridolfo, AS | 1 |
| Wellman, HN | 1 |
| Bird, HA | 1 |
| Hill, J | 1 |
| Sitton, NG | 1 |
| Dixon, JS | 1 |
| Wright, V | 1 |
1 review available for etidronate and Arthritis, Rheumatoid
| Article | Year |
|---|---|
[Osteoporosis in the patients with rheumatoid arthritis (3) : the efficacy and the selection of the osteoporosis therapeutic drug].
Topics: Alendronate; Arthritis, Rheumatoid; Bone Density Conservation Agents; Etidronic Acid; Humans; Osteop | 2007 |
14 trials available for etidronate and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Two year randomized controlled trial of etidronate in rheumatoid arthritis: changes in serum aminoterminal telopeptides correlate with radiographic progression of disease.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Collagen; Collagen Type I; Dis | 2003 |
Bone resorption and inflammatory inhibition efficacy of intermittent cyclical etidronate therapy in rheumatoid arthritis.
Topics: Aged; Alkaline Phosphatase; Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Densi | 2003 |
Effect of cyclical intermittent etidronate therapy on circulating osteoprotegerin levels in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Arthrography; Collagen Type I; Disease Progression; Dose-Respons | 2003 |
Skeletal benefit after one year of risedronate therapy in patients with rheumatoid arthritis and glucocorticoid-induced osteoporosis: a prospective study.
Topics: Alkaline Phosphatase; Arthritis, Rheumatoid; Bone and Bones; C-Reactive Protein; Cross-Linking Reage | 2004 |
Comparative studies on effect of risedronate and alfacalcidol against glucocorticoid-induced osteoporosis in rheumatoid arthritic patients.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Biomarkers; Bone Density; Bone Density Conservation | 2007 |
Osteoclast inhibitory effects of vitamin K2 alone or in combination with etidronate or risedronate in patients with rheumatoid arthritis: 2-year results.
Topics: Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Bone Density; Bone Density Conservation Agents; C | 2008 |
Effects of bisphosphonates on fracture incidence and bone metabolism in rheumatoid arthritis patients in general practice taking long-term corticosteroid therapy: a retrospective study.
Topics: Aged; Alendronate; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone and Bones; Bone Density Con | 2008 |
Intermittent cyclic therapy with etidronate in the prevention of corticosteroid induced bone loss.
Topics: Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Bone Density; Cohort Studies; Dose-Resp | 1994 |
Cyclical etidronate increases bone density in the spine and hip of postmenopausal women receiving long term corticosteroid treatment. A double blind, randomised placebo controlled study.
Topics: Aged; Analysis of Variance; Arthritis, Rheumatoid; Bone Density; Calcium; Double-Blind Method; Drug | 1998 |
Evaluation of the efficacy of etidronate therapy in preventing glucocorticoid-induced bone loss in patients with inflammatory rheumatic diseases. A randomized study.
Topics: Absorptiometry, Photon; Alkaline Phosphatase; Amino Acids; Arthritis, Rheumatoid; Bone Density; Doub | 1999 |
The prevention of corticosteroid-induced bone loss with intermittent cyclical etidronate.
Topics: Absorptiometry, Photon; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Alkaline Phosphatase; Arth | 1999 |
Prevention of bone loss with risedronate in glucocorticoid-treated rheumatoid arthritis patients.
Topics: Administration, Oral; Aged; Arthritis, Rheumatoid; Bone Density; Calcium Channel Blockers; Double-Bl | 2000 |
Painful multifocal arthritis: therapy with rhenium 186 hydroxyethylidenediphosphonate ((186)Re HEDP) after failed treatment with medication--initial results of a prospective study.
Topics: Arthritis, Rheumatoid; Etidronic Acid; Female; Humans; Male; Middle Aged; Organometallic Compounds; | 2001 |
A clinical and biochemical assessment of etidronate disodium in patients with active rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Bone and Bones; Clinical Trials as Topic; E | 1988 |
11 other studies available for etidronate and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Bisphosphonate-related osteonecrosis of jaw (BRONJ) in Japanese population: a case series of 13 patients at our clinic.
Topics: Administration, Oral; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Alendronate; Anti-Bacterial | 2013 |
Synergistic effects of ethanol and isopentenyl pyrophosphate on expansion of γδ T cells in synovial fluid from patients with arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cell Proliferation; Cell Survival; Drug Synergism; Ethanol; Etid | 2014 |
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment.
Topics: Arthritis, Rheumatoid; Case-Control Studies; Etidronic Acid; Female; Humans; Kynurenine; Methotrexat | 2003 |
Inhibitory effect of bone resorption and inflammation with etidronate therapy in patients with rheumatoid arthritis for 3 years and in vitro assay in arthritis models.
Topics: Aged; Alkaline Phosphatase; Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Densi | 2006 |
Prevalence of evaluation and treatment of glucocorticoid-induced osteoporosis in men.
Topics: Aged; Aged, 80 and over; Alendronate; Arthritis, Rheumatoid; Bone Density; Bone Density Conservation | 2006 |
Sequential joint scintigraphy in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Etidronic Acid; Female; Humans; Joints; Male; Middle Aged; Organ | 1983 |
APD in Paget's disease of bone. Role of the mononuclear phagocyte system?
Topics: Animals; Arthritis, Rheumatoid; Calcitonin; Clodronic Acid; Diphosphonates; Drug Therapy, Combinatio | 1980 |
Intermittent etidronate and corticosteroid-induced osteoporosis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Etidronic Acid; Female; Humans; Male; Osteoporosis; | 1997 |
Should postmenopausal women with rheumatoid arthritis who are starting corticosteroid treatment be screened for osteoporosis? A cost-effectiveness analysis.
Topics: Arthritis, Rheumatoid; Cost-Benefit Analysis; Estrogen Replacement Therapy; Etidronic Acid; Female; | 2000 |
Identification of hydroxyapatite crystals in synovial fluid.
Topics: Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Chondrocalcinosis; Etidronic Acid; Female; | 1979 |
A quantitative evaluation of rheumatoid arthritic activity with Tc-99m HEDP.
Topics: Adult; Arthritis, Rheumatoid; Etidronic Acid; Evaluation Studies as Topic; Female; Humans; Male; Mid | 1977 |