Page last updated: 2024-10-26

etidronate and Arteriosclerosis

etidronate has been researched along with Arteriosclerosis in 11 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
" At 24 hours after dosing in healthy rabbits, the mean aorta to plasma ratios of clodronate, etidronate, and pamidronate were, respectively, 2."1.29Accumulation of bisphosphonates in the aorta and some other tissues of healthy and atherosclerotic rabbits. ( Mönkkönen, J; Urtti, A; Ylitalo, P; Ylitalo, R, 1996)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shimshi, M1
Abe, E1
Fisher, EA1
Zaidi, M1
Fallon, JT1
Kramsch, DM3
Aspen, AJ1
Rozler, LJ1
Zhu, BQ1
Sun, YP1
Sievers, RE1
Isenberg, WM1
Moorehead, TJ1
Parmley, WW1
Ylitalo, R1
Mönkkönen, J1
Urtti, A1
Ylitalo, P1
Hollander, W1
Paddock, J1
Nagraj, S1
Colombo, M1
Kirkpatrick, B1
Wagner, WD1
Clarkson, TB1
Foster, J1
Chan, CT1
Meradji, M1
de Villeneuve, VH1
Huber, J1
de Bruijn, WC1
Pearse, RG1
Daoud, AS1
Frank, AS1
Jarmolych, J1
Fritz, KE1
Caniggia, A1
Gennari, C1
Picchi, M1

Other Studies

11 other studies available for etidronate and Arteriosclerosis

ArticleYear
Bisphosphonates induce inflammation and rupture of atherosclerotic plaques in apolipoprotein-E null mice.
    Biochemical and biophysical research communications, 2005, Mar-18, Volume: 328, Issue:3

    Topics: Alendronate; Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Carotid Stenosis; Diphosphonates;

2005
Atherosclerosis: Prevention by agents not affecting abnormal levels of blood lipids.
    Science (New York, N.Y.), 1981, Sep-25, Volume: 213, Issue:4515

    Topics: Animals; Aorta; Arteries; Arteriosclerosis; Calcium; Cholesterol; Diet, Atherogenic; Diphosphonates;

1981
Effects of etidronate and lovastatin on the regression of atherosclerosis in cholesterol-fed rabbits.
    Cardiology, 1994, Volume: 85, Issue:6

    Topics: Animals; Aortic Diseases; Arteriosclerosis; Body Weight; Bone and Bones; Calcium; Diet, Atherogenic;

1994
Accumulation of bisphosphonates in the aorta and some other tissues of healthy and atherosclerotic rabbits.
    The Journal of laboratory and clinical medicine, 1996, Volume: 127, Issue:2

    Topics: Analysis of Variance; Animals; Aorta; Aortic Valve; Arteriosclerosis; Carbon Radioisotopes; Clodroni

1996
Effects of anticalcifying and antifibrobrotic drugs on pre-established atherosclerosis in the rabbit.
    Atherosclerosis, 1979, Volume: 33, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Azetidines; Azetines; Calcium; Cholesterol; Colchicine; Diet, Athe

1979
Contrasting effects of ethane-1-hydroxy-1,1-diphosphonate (EHDP) on the regression of two types of dietary-induced atherosclerosis.
    Atherosclerosis, 1977, Volume: 27, Issue:4

    Topics: Animals; Aorta, Thoracic; Arteries; Arteriosclerosis; Bone and Bones; Calcium; Cholesterol; Columbid

1977
The effect of agents interfering with soft tissue calcification and cell proliferation on calcific fibrous-fatty plaques in rabbits.
    Circulation research, 1978, Volume: 42, Issue:4

    Topics: Animals; Aorta; Arteriosclerosis; Calcinosis; Cholesterol; Demecolcine; Diet, Atherogenic; Elastin;

1978
Idiopathic infantile arterial calcification in siblings: radiologic diagnosis and successful treatment.
    The Journal of pediatrics, 1978, Volume: 92, Issue:3

    Topics: Arteriosclerosis; Calcinosis; Coronary Disease; Etidronic Acid; Female; Humans; Infant, Newborn; Inf

1978
The effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) on necrosis of atherosclerotic lesions.
    Atherosclerosis, 1987, Volume: 67, Issue:1

    Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Calcium; Cholesterol; Diet, Atherogenic; DNA; Etidronic

1987
Calcium antagonists and atherosclerosis.
    Advances in experimental medicine and biology, 1985, Volume: 183

    Topics: Animals; Arteriosclerosis; Calcium; Cholesterol; Collagen; Diet, Atherogenic; Diphosphonates; Elasti

1985
[Diphosphonate (disodium etidronate) lowers cholesterol and total lipid levels in the blood of humans].
    Bollettino della Societa italiana di biologia sperimentale, 1974, Sep-15, Volume: 50, Issue:17

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Etidronic Acid; Humans; Hypercholesterolemi

1974