Page last updated: 2024-10-26

etidronate and Aging

etidronate has been researched along with Aging in 16 studies

Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"If patients with osteoporosis are being diagnosed and effective treatments used with increasing frequency in the population, rates of hip and wrist fractures will remain stable or possibly decrease."1.33Population trends in BMD testing, treatment, and hip and wrist fracture rates: are the hip fracture projections wrong? ( Adachi, JD; Hawker, G; Jaakkimainen, L; Jaglal, SB; Kreder, H; Mamdani, M; Weller, I, 2005)
" These findings indicated that the long-term administration of PGE2 alone cannot maintain or continue to add bone mass in ovx rats but that co-treatment of a PGE2 with an anti-resorptive or activation agent can resist the influence of the mechanostat induced bone loss as well as continue to add bone."1.29Co-treatment of PGE2 and risedronate is better than PGE2 alone in the long-term treatment of ovariectomized-induced osteopenic rats. ( Chen, YY; Ijiri, K; Jee, WS; Ke, HZ; Ma, Y, 1995)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's9 (56.25)18.2507
2000's6 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Verhaar, HJ1
Fukunaga, M1
Jaglal, SB1
Weller, I1
Mamdani, M1
Hawker, G1
Kreder, H1
Jaakkimainen, L1
Adachi, JD1
Ito, M1
Nakayama, K1
Konaka, A1
Sakata, K1
Ikeda, K1
Maruyama, T1
Fogelman, I1
Bessent, RG1
Gordon, D1
Qi, H1
Li, M1
Wronski, TJ2
Jee, WS5
Lin, BY2
Ma, YF3
Ke, HZ5
Steiniche, T1
Li, QN1
Xie, H1
Huang, LF1
Liang, NC1
Ma, Y1
Chen, YY2
Ijiri, K1
Lin, CH1
Li, XJ1
Mosekilde, L2
Thomsen, JS2
McOsker, JE1
Beauchesne, MF1
Miller, PF1
Trémollières, F1
Iwaniec, UT1
Mitova-Caneva, NG1
Tang, LY1
Kimmel, DB1

Reviews

4 reviews available for etidronate and Aging

ArticleYear
[Bone mass measurement and evaluation of therapeutical response].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 2

    Topics: Absorptiometry, Photon; Aging; Alendronate; Biomarkers; Bone Density; Calcium; Estrogen Replacement

2004
Bone histomorphometry in the pathophysiological evaluation of primary and secondary osteoporosis and various treatment modalities.
    APMIS. Supplementum, 1995, Volume: 51

    Topics: Adult; Aged; Aging; Benzothiadiazines; Bone and Bones; Calcium; Diuretics; Estrogens; Etidronic Acid

1995
Etidronate and alendronate in the treatment of postmenopausal osteoporosis.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:5

    Topics: Aging; Alendronate; Bone Density; Clinical Trials as Topic; Data Collection; Etidronic Acid; Female;

1999
[Alternatives to hormonal treatment for the prevention of postmenopausal osteoporosis: the bisphosphonates].
    Gynecologie, obstetrique & fertilite, 2001, Volume: 29, Issue:11

    Topics: Aging; Alendronate; Diphosphonates; Estrogen Replacement Therapy; Etidronic Acid; Female; Humans; Mi

2001

Other Studies

12 other studies available for etidronate and Aging

ArticleYear
[Treatment of osteoporosis in the elderly: what is the evidence?].
    Tijdschrift voor gerontologie en geriatrie, 2008, Volume: 39, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alendronate; Bone Density; Bone Density Conservation Ag

2008
Population trends in BMD testing, treatment, and hip and wrist fracture rates: are the hip fracture projections wrong?
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:6

    Topics: Aged; Aging; Bone Density; Drug Prescriptions; Etidronic Acid; Female; Fractures, Bone; Hip Fracture

2005
Effects of a prostaglandin EP4 agonist, ONO-4819, and risedronate on trabecular microstructure and bone strength in mature ovariectomized rats.
    Bone, 2006, Volume: 39, Issue:3

    Topics: Aging; Animals; Bone Density; Etidronic Acid; Female; Heptanoates; Ovariectomy; Prostaglandins E; Ra

2006
A critical assessment of bone scan quantitation (bone to soft tissue ratios) in the diagnosis of metabolic bone disease.
    European journal of nuclear medicine, 1981, Volume: 6, Issue:3

    Topics: Adult; Aged; Aging; Bone and Bones; Bone Diseases, Metabolic; Chronic Kidney Disease-Mineral and Bon

1981
A comparison of the anabolic effects of parathyroid hormone at skeletal sites with moderate and severe osteopenia in aged ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:6

    Topics: Aging; Animals; Biomarkers; Bone Development; Bone Diseases, Metabolic; Bone Remodeling; Calcitonin;

1995
Extra cancellous bone induced by combined prostaglandin E2 and risedronate administration is maintained after their withdrawal in older female rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:6

    Topics: Aging; Analysis of Variance; Animals; Body Weight; Bone Development; Bone Resorption; Calcium Channe

1995
Risedronate pretreatment does not hamper the anabolic effects of prostaglandin E2 in ovx rats.
    Bone, 1995, Volume: 17, Issue:4 Suppl

    Topics: Aging; Animals; Dinoprostone; Drug Evaluation, Preclinical; Drug Interactions; Etidronic Acid; Femal

1995
Co-treatment of PGE2 and risedronate is better than PGE2 alone in the long-term treatment of ovariectomized-induced osteopenic rats.
    Bone, 1995, Volume: 17, Issue:4 Suppl

    Topics: Aging; Animals; Body Weight; Bone Development; Bone Diseases, Metabolic; Dinoprostone; Drug Therapy,

1995
Prostaglandin E2 (PGE2) and risedronate was superior to PGE2 alone in maintaining newly added bone in the cortical bone site after withdrawal in older intact rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:2

    Topics: Age Factors; Aging; Animals; Bone and Bones; Bone Density; Calcium Channel Blockers; Dinoprostone; D

1997
No loss of biomechanical effects after withdrawal of short-term PTH treatment in an aged, osteopenic, ovariectomized rat model.
    Bone, 1997, Volume: 20, Issue:5

    Topics: Aging; Animals; Biomechanical Phenomena; Bone and Bones; Bone Diseases, Metabolic; Calcium Channel B

1997
Sequential treatment with basic fibroblast growth factor and PTH is more efficacious than treatment with PTH alone for increasing vertebral bone mass and strength in osteopenic ovariectomized rats.
    Endocrinology, 2002, Volume: 143, Issue:7

    Topics: Aging; Animals; Biomechanical Phenomena; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Ca

2002
Restoring and maintaining bone in osteopenic female rat skeleton: I. Changes in bone mass and structure.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1992, Volume: 7, Issue:9

    Topics: Aging; Animals; Body Weight; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Bone Resorption

1992