etidronate has been researched along with Adult Rickets in 22 studies
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.
etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to examine bone histomorphometry before and after 2 yr of a double blind trial of etidronate to determine whether etidronate was associated with the development of osteomalacia and to clarify the mechanism of action." | 5.07 | Bone histomorphometric changes after cyclic therapy with phosphate and etidronate disodium in women with postmenopausal osteoporosis. ( Huffer, WE; Miller, PD; Ott, SM; Watts, NB; Woodson, GC, 1994) |
| "No publications have reported on osteomalacia in patients receiving intermittent cyclical therapy with etidronate (a bisphosphonate) and undergoing long-term hemodialysis (HD)." | 4.02 | Case report: Osteomalacia due to bisphosphonate treatment in a patient on hemodialysis. ( Hatano, M; Hirota, Y; Hoshino, J; Isawa, K; Kitajima, I; Nakamura, M; Sawa, N; Ubara, Y; Yamamoto, S, 2021) |
| "Inhibition of skeletal mineralisation is a well-recognized complication of disodium etidronate therapy that was identified in the earliest studies of its use in osteoporosis and Paget's disease." | 3.70 | Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget's disease. ( MacGowan, JR; Morris, VH; Pringle, J; Stamp, TC, 2000) |
| " To evaluate the role of bone remodeling and mature osteoblastic function in aluminum-induced neoosteogenesis, we compared the osteogenic effects of aluminum in normal beagles to those in animals with low turnover osteomalacia induced by treatment with etidronate [1-hydroxyethane-1,1-diphosphoric acid (HEBP)]." | 3.68 | Effects of etidronate-mediated suppression of bone remodeling on aluminum-induced de novo bone formation. ( Drezner, MK; Quarles, LD, 1992) |
| "Transiliac bone biopsies carried out on 13 patients with Paget's disease to evaluate the effects of low-dose diphosphonate (disodium etidronate) therapy showed focal osteomalacia in the 9 patients in whom post-therapy specimens were taken through pagetic bone." | 3.67 | Focal osteomalacia due to low-dose diphosphonate therapy in Paget's disease. ( Boyce, BF; Boyle, IT; Fogelman, I; Johnston, E; Ralston, S; Smith, L, 1984) |
| "By 24 months, renal tubular acidosis was improved and the bone density had normalized." | 1.39 | Successful treatment of osteomalacia caused by renal tubular acidosis associated with Sjögren's syndrome. ( Hirata, S; Inokuchi, N; Mori, H; Okada, Y; Saito, K; Tanaka, Y; Yamamoto, S, 2013) |
| "Osteomalacia is caused by inadequate or delayed mineralization of bone and is treated by correcting the abnormal intake, loss, or metabolism of vitamin D, phosphate, and calcium." | 1.27 | Osteoporosis, osteomalacia, rickets, and Paget's disease. ( Gall, EP; Nugent, CA; Pitt, MJ, 1984) |
| "Histologic proof of renal osteodystrophy had been obtained in all patients." | 1.26 | Bone scintigraphy in renal osteodystrophy. ( de Graaf, P; de Graeff, J; Pauwels, EK; Schicht, IM; te Velde, J, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (54.55) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Hatano, M | 1 |
| Kitajima, I | 1 |
| Yamamoto, S | 2 |
| Nakamura, M | 1 |
| Isawa, K | 1 |
| Hirota, Y | 1 |
| Hoshino, J | 1 |
| Sawa, N | 1 |
| Ubara, Y | 1 |
| Okada, Y | 1 |
| Mori, H | 1 |
| Hirata, S | 1 |
| Saito, K | 1 |
| Inokuchi, N | 1 |
| Tanaka, Y | 1 |
| Hoppé, E | 1 |
| Masson, C | 1 |
| Laffitte, A | 1 |
| Chappard, D | 1 |
| Audran, M | 1 |
| Labinson, P | 1 |
| Taxel, P | 1 |
| Sato, K | 1 |
| Boyce, BF | 1 |
| Smith, L | 1 |
| Fogelman, I | 3 |
| Johnston, E | 1 |
| Ralston, S | 1 |
| Boyle, IT | 1 |
| Smith, ML | 1 |
| Nugent, CA | 1 |
| Gall, EP | 1 |
| Pitt, MJ | 1 |
| Paterson, CR | 1 |
| Feely, J | 1 |
| Evans, RA | 2 |
| Dunstan, CR | 1 |
| Hills, E | 1 |
| Wong, SY | 1 |
| Raisz, LG | 1 |
| Bessent, RG | 1 |
| Gordon, D | 1 |
| Ott, SM | 1 |
| Woodson, GC | 1 |
| Huffer, WE | 1 |
| Miller, PD | 1 |
| Watts, NB | 1 |
| Thomas, T | 1 |
| Lafage, MH | 1 |
| Alexandre, C | 2 |
| Adami, S | 1 |
| Zamberlan, N | 1 |
| MacGowan, JR | 1 |
| Pringle, J | 1 |
| Morris, VH | 1 |
| Stamp, TC | 1 |
| de Graaf, P | 1 |
| Schicht, IM | 1 |
| Pauwels, EK | 1 |
| te Velde, J | 1 |
| de Graeff, J | 1 |
| Chapuy, MC | 1 |
| Meunier, P | 1 |
| Ryckewaert, A | 1 |
| Lemaire, V | 1 |
| Tubiana, M | 1 |
| Quarles, LD | 1 |
| Drezner, MK | 1 |
| Gibbs, CJ | 1 |
| Aaron, JE | 1 |
| Peacock, M | 1 |
2 reviews available for etidronate and Adult Rickets
| Article | Year |
|---|---|
[Drug-induced osteomalacia].
Topics: Anticonvulsants; Etidronic Acid; Ferric Compounds; Ferric Oxide, Saccharated; Glucaric Acid; Hematin | 2007 |
Adverse effects of bisphosphonates. A comparative review.
Topics: Acute Kidney Injury; Animals; Diphosphonates; Etidronic Acid; Gastrointestinal Diseases; Humans; Ost | 1996 |
2 trials available for etidronate and Adult Rickets
| Article | Year |
|---|---|
Bone histomorphometric changes after cyclic therapy with phosphate and etidronate disodium in women with postmenopausal osteoporosis.
Topics: Bone and Bones; Dose-Response Relationship, Drug; Double-Blind Method; Etidronic Acid; Female; Human | 1994 |
Osteomalacia in Paget's disease treated with short term, high dose sodium etidronate.
Topics: Aged; Bone and Bones; Etidronic Acid; Female; Humans; Male; Middle Aged; Minerals; Osteitis Deforman | 1986 |
18 other studies available for etidronate and Adult Rickets
| Article | Year |
|---|---|
Case report: Osteomalacia due to bisphosphonate treatment in a patient on hemodialysis.
Topics: Bone and Bones; Bone Density Conservation Agents; Calcitriol; Cholecalciferol; Etidronic Acid; Human | 2021 |
Successful treatment of osteomalacia caused by renal tubular acidosis associated with Sjögren's syndrome.
Topics: Acidosis, Renal Tubular; Bone Density Conservation Agents; Drug Therapy, Combination; Etidronic Acid | 2013 |
Osteomalacia in a patient with Paget's bone disease treated with long-term etidronate.
Topics: Aged, 80 and over; Alkaline Phosphatase; Biopsy; Bone Density Conservation Agents; Calcification, Ph | 2012 |
Multiple fractures in a woman receiving 24 years of etidronate treatment for Paget's disease.
Topics: Aged; Bone Density Conservation Agents; Diphosphonates; Etidronic Acid; Female; Fractures, Spontaneo | 2007 |
Focal osteomalacia due to low-dose diphosphonate therapy in Paget's disease.
Topics: Aged; Biopsy; Bone and Bones; Bone Resorption; Etidronic Acid; Female; Humans; Male; Middle Aged; Mi | 1984 |
Diphosphonates in the evaluation of metabolic bone disease.
Topics: Bone and Bones; Bone Diseases, Metabolic; Chronic Kidney Disease-Mineral and Bone Disorder; Diphosph | 1982 |
Osteoporosis, osteomalacia, rickets, and Paget's disease.
Topics: Anti-Inflammatory Agents; Calcitonin; Calcium; Diet; Estrogens; Etidronic Acid; Humans; Osteitis Def | 1984 |
Vitamin D metabolites and analogues, diphosphonates, danazol, and bromocriptine.
Topics: Acromegaly; Bromocriptine; Calcitriol; Danazol; Endometriosis; Etidronic Acid; Female; Fibrocystic B | 1983 |
Pathologic fracture due to severe osteomalacia following low-dose diphosphonate treatment of Paget's disease of bone.
Topics: Etidronic Acid; Fractures, Spontaneous; Humans; Male; Middle Aged; Osteitis Deformans; Osteomalacia; | 1983 |
Disodium etidronate (EHDP)
Topics: Etidronic Acid; Fractures, Spontaneous; Humans; Osteitis Deformans; Osteomalacia | 1984 |
New diphosphonates to block bone resorption.
Topics: Animals; Bone Resorption; Breast Neoplasms; Clodronic Acid; Diphosphonates; Double-Blind Method; Eti | 1980 |
A critical assessment of bone scan quantitation (bone to soft tissue ratios) in the diagnosis of metabolic bone disease.
Topics: Adult; Aged; Aging; Bone and Bones; Bone Diseases, Metabolic; Chronic Kidney Disease-Mineral and Bon | 1981 |
Atypical osteomalacia after 2 year etidronate intermittent cyclic administration in osteoporosis.
Topics: Aged; Bone Density; Drug Administration Schedule; Etidronic Acid; Female; Humans; Osteomalacia; Oste | 1995 |
Gross vertebral collapse associated with long-term disodium etidronate treatment for pelvic Paget's disease.
Topics: Aged; Alkaline Phosphatase; Anti-Inflammatory Agents; Arthralgia; Diphosphonates; Etidronic Acid; Fo | 2000 |
Bone scintigraphy in renal osteodystrophy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Bone and Bones; Chronic Kidney Disease-Mineral and Bone Dis | 1978 |
[The hypocalcemia test, using human and salmon synthetic calcitonins. Paradoxical hypercalcemic responses. Responses in patients with Paget's disease treated with EHDP].
Topics: Calcitonin; Calcium; Dose-Response Relationship, Drug; Etidronic Acid; Hormones; Humans; Hyperparath | 1979 |
[Non-hormonal drug treatment in Paget's disease].
Topics: Alkaline Phosphatase; Etidronic Acid; Humans; Hydroxyproline; Organophosphorus Compounds; Osteitis D | 1975 |
Effects of etidronate-mediated suppression of bone remodeling on aluminum-induced de novo bone formation.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Bone and Bones; Bone Development; Bone Rem | 1992 |