Page last updated: 2024-08-21

ethylnitrosourea and Sterility, Male

ethylnitrosourea has been researched along with Sterility, Male in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's3 (17.65)18.2507
2000's7 (41.18)29.6817
2010's4 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, J; Chen, Y; Gu, Y; Gui, Y; Guo, H; Huang, W; Jiang, Z; Li, C; Li, Y; Lin, S; Luo, M; Ma, Q; Mou, L; Wang, T; Wu, H; Xia, J; Yang, B; Yang, L1
Akiyama, K; Ann Handel, M; Chikushi, M; Fujiwara, Y; Kunieda, T; Matsumoto, H; Srivastava, A1
Akiyama, K; Asano, Y; Kunieda, T; Noguchi, J; Takahashi, S; Tsuji, T1
Abe, K; Adamski, J; Adler, T; Boersma, A; Busch, DH; Calzada-Wack, J; de Angelis, MH; Esposito, I; Fuchs, H; Gailus-Durner, V; Hans, W; Kalaydjiev, S; Kametani, Y; Katan, M; Klaften, M; Klingenspor, M; Maraslioglu, M; Marschall, S; Mossbrugger, I; Prehn, C; Rathkolb, B; Rozman, J; Shimada, S; Soewarto, D; Wagner, S; Wolf, E; Wurst, W; Yu, P1
Beier, DR; Finlayson, C; Fisher, LA; Harris, RM; Hurley, LA; Jameson, JL; Mason, C; Moran, JL; Tong, M; Weiss, J1
Blanquet, V; Hrabĕ de Angelis, M; Soewarto, D1
Handel, MA; Lessard, C; Lothrop, H; Schimenti, JC1
Harris, T; Marquez, B; Schimenti, J; Suarez, S1
Akimaru, S; Akiyama, K; Asano, Y; Katayama, K; Khalaj, M; Kiyosu, C; Kunieda, T; Masoudi, AA; Noguchi, J; Takahashi, S; Tsuji, T1
Abbasi, AR; Akiyama, K; Khalaj, M; Kunieda, T; Nishimura, R; Noguchi, J; Okuda, K; Tsuji, T1
Ficsor, G; Panda, BB; Rodriguez, M1
Carpenter, DA; Handel, MA; Rinchik, EM1
Ehling, UH; Favor, J; Neuhäuser-Klaus, A; van Zeeland, AA; Wulff, A1
Horsthemke, B; Ji, Y; Johnson, D; Nicholls, RD; Ren, X; Rinchik, EM; Russell, LB; Stubbs, L; Walkowicz, M1
Bode, VC; Carpenter, DA; Chapman, V; Cordes, S; Favor, J; Hrabé de Angelis, M; Hunsicker, PR; Justice, MJ; Miller, D; Moser, A; Neuhauser-Klaus, A; Rinchik, EM; Russell, WL; Soewarto, D; Weber, JS1
Bangham, JW; Hunsicker, PR; Kelly, EM; Maddux, SC; Phipps, EL; Russell, WL1
Carpenter, DA; Hitotsumachi, S; Russell, WL1

Other Studies

17 other study(ies) available for ethylnitrosourea and Sterility, Male

ArticleYear
A nonsense mutation in Ccdc62 gene is responsible for spermiogenesis defects and male infertility in repro29/repro29 mice.
    Biology of reproduction, 2017, 03-01, Volume: 96, Issue:3

    Topics: Acrosome; Adaptor Proteins, Signal Transducing; Animals; Base Sequence; Carrier Proteins; Codon, Nonsense; Ethylnitrosourea; Female; Golgi Matrix Proteins; Infertility, Male; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Sequence Analysis, DNA; Spermatogenesis; Testis; Transcription Factors

2017
An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility.
    Reproduction (Cambridge, England), 2015, Volume: 149, Issue:1

    Topics: Alkylating Agents; Animals; Blotting, Western; Cells, Cultured; Ethylnitrosourea; Immunoenzyme Techniques; Infertility, Male; Ligases; Male; Meiosis; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mutation, Missense; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spermatocytes; Spermatogenesis

2015
Characterization and linkage mapping of an ENU-induced mutant mouse with defective spermatogenesis.
    Experimental animals, 2009, Volume: 58, Issue:5

    Topics: Alkylating Agents; Animals; Chromosome Mapping; Ethylnitrosourea; Female; Gene Expression Regulation, Developmental; Genetic Linkage; Genitalia, Male; Homozygote; HSC70 Heat-Shock Proteins; Infertility, Male; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Organ Size; Spermatocytes; Spermatogenesis; Testis

2009
A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model.
    Arthritis and rheumatism, 2011, Volume: 63, Issue:5

    Topics: Animals; Arthritis, Experimental; Body Composition; Ethylnitrosourea; Flow Cytometry; Infertility, Male; Male; Mice; Mice, Mutant Strains; Mutagenesis; Mutation; Phospholipase C gamma; Polymorphism, Single Nucleotide; Sperm Motility

2011
ENU mutagenesis in mice identifies candidate genes for hypogonadism.
    Mammalian genome : official journal of the International Mammalian Genome Society, 2012, Volume: 23, Issue:5-6

    Topics: Animals; Ethylnitrosourea; Humans; Hypogonadism; Infertility, Male; Male; Mice; Mice, Inbred C57BL; Mutagenesis; Proteins

2012
Random ENU mutagenesis.
    Methods in molecular biology (Clifton, N.J.), 2003, Volume: 209

    Topics: Animal Husbandry; Animals; Breeding; Chromosome Mapping; Crosses, Genetic; Databases, Factual; DNA; Ethylnitrosourea; Female; Genes, Dominant; Genes, Recessive; Infertility, Male; Male; Mice; Models, Animal; Mutagenesis; Phenotype; Species Specificity

2003
Mutagenesis-generated mouse models of human infertility with abnormal sperm.
    Human reproduction (Oxford, England), 2007, Volume: 22, Issue:1

    Topics: Animals; Bacterial Proteins; Calcium-Binding Proteins; Disease Models, Animal; Ethylnitrosourea; Humans; Immunohistochemistry; Infertility, Male; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Mutagenesis; Phenotype; Spermatozoa

2007
Sperm motility defects and infertility in male mice with a mutation in Nsun7, a member of the Sun domain-containing family of putative RNA methyltransferases.
    Biology of reproduction, 2007, Volume: 77, Issue:2

    Topics: Animals; Cloning, Molecular; Ethylnitrosourea; Female; Infertility, Male; Male; Methyltransferases; Mice; Mice, Inbred C3H; Microsatellite Repeats; Mutagenesis; Sperm Motility; Sperm Tail; Spermatozoa; tRNA Methyltransferases

2007
A new ENU-induced mutant mouse with defective spermatogenesis caused by a nonsense mutation of the syntaxin 2/epimorphin (Stx2/Epim) gene.
    The Journal of reproduction and development, 2008, Volume: 54, Issue:2

    Topics: Animals; Codon, Nonsense; DNA; Ethylnitrosourea; Giant Cells; HSC70 Heat-Shock Proteins; Infertility, Male; Male; Membrane Glycoproteins; Mice; Mice, Mutant Strains; RNA; Spermatocytes; Spermatogenesis; Syntaxin 1

2008
Leydig cell hyperplasia in an ENU-induced mutant mouse with germ cell depletion.
    The Journal of reproduction and development, 2008, Volume: 54, Issue:3

    Topics: Alkylating Agents; Animals; Cell Count; Disease Models, Animal; Ethylnitrosourea; Homozygote; Hyperplasia; Infertility, Male; Leydig Cells; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Phenotype; Sertoli Cells; Spermatogenesis; Spermatozoa; Testosterone

2008
Testes weight reflect ethylnitrosourea induced histopathology in mice.
    Toxicology letters, 1983, Volume: 17, Issue:1-2

    Topics: Animals; Ethylnitrosourea; Infertility, Male; Kinetics; Male; Mice; Nitrosourea Compounds; Organ Size; Testis

1983
Pleiotropy in microdeletion syndromes: neurologic and spermatogenic abnormalities in mice homozygous for the p6H deletion are likely due to dysfunction of a single gene.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jul-03, Volume: 92, Issue:14

    Topics: Animals; Chromosome Mapping; Crosses, Genetic; Ethylnitrosourea; Female; Gene Deletion; Genes, Recessive; Genetic Carrier Screening; Genetic Markers; Genotype; Homozygote; Infertility, Male; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis; Mutagens; Nervous System Diseases; Phenotype; Spermatogenesis; Spermatozoa; Syndrome; Testis

1995
The effect of the interval between dose applications on the observed specific-locus mutation rate in the mouse following fractionated treatments of spermatogonia with ethylnitrosourea.
    Mutation research, 1997, Mar-21, Volume: 374, Issue:2

    Topics: Animals; Ethylnitrosourea; Female; Genetic Markers; Infertility, Male; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Mutation; Phenotype; Spermatogenesis; Spermatogonia; Time Factors

1997
Molecular characterization of radiation- and chemically induced mutations associated with neuromuscular tremors, runting, juvenile lethality, and sperm defects in jdf2 mice.
    Mammalian genome : official journal of the International Mammalian Genome Society, 1999, Volume: 10, Issue:9

    Topics: Alleles; Animals; Base Sequence; DNA Primers; DNA, Complementary; Ethylnitrosourea; Female; Gene Rearrangement; Genes, Lethal; Growth Disorders; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Infertility, Male; Male; Mice; Mice, Mutant Strains; Molecular Sequence Data; Muridae; Mutagens; Mutation; Neuromuscular Diseases; Phenotype; Sequence Deletion; Sequence Homology, Nucleic Acid; Spermatozoa

1999
Effects of ENU dosage on mouse strains.
    Mammalian genome : official journal of the International Mammalian Genome Society, 2000, Volume: 11, Issue:7

    Topics: Animals; Dose-Response Relationship, Drug; Ethylnitrosourea; Hybridization, Genetic; Infertility, Male; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Mice, Mutant Strains

2000
Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse.
    Proceedings of the National Academy of Sciences of the United States of America, 1979, Volume: 76, Issue:11

    Topics: Alleles; Animals; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Infertility; Infertility, Male; Male; Mice; Mutagens; Nitrosourea Compounds; Spermatogonia

1979
Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:19

    Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Infertility, Male; Male; Mice; Mutagens; Mutation; Pregnancy; Spermatogonia; Spermatozoa; Stem Cells; Time Factors

1985