Page last updated: 2024-08-21

ethylnitrosourea and Retinal Degeneration

ethylnitrosourea has been researched along with Retinal Degeneration in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's7 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Do, HJ; Kim, KY; Ma, JY; Oh, TW; Park, KI1
Haider, NB; Heuermann, L; Nystuen, AM; Sachs, AJ; Yuan, Y1
Beutler, B; Du, X; Flannery, JG; Gong, X; Liu, H; Ridge, KD; Wang, M; Xia, CH1
Collin, GB; Edwards, MM; Gifford, E; Hicks, WL; Lamb, BT; Maphis, N; MarĂ­n de Evsikova, C; Naggert, JK; Nishina, PM; Peachey, NS; Varvel, NH; Whiting, C; Wu, J1
Gondo, Y; Ikeda, K; Kaneda, H; Kobayashi, K; Kurihara, Y; Masuya, H; Miura, I; Nishida, K; Noda, T; Sato, H; Sezutsu, H; Suzuki, T; Tamai, M; Wakana, S; Yokokura, S1
Hicks, WL; LaVail, MM; Maddox, DM; Naggert, JK; Nishina, PM; Vollrath, D1
Kanematsu, S; Kimura-Kawanaka, A; Kuro-Kuwata, M; Lai, YC; Miki, H; Sasaki, T; Tsubura, A; Uehara, N; Yoshizawa, K; Yuri, T1
Hicks, W; Naggert, JK; Nishina, PM; Shi, LY; Wang, J; Won, J1
Baier, H; Goldsmith, P; Harris, WA1
Li, L; Maaswinkel, H; Mason, B1
Cross, SH; Gautier, P; Hart, AW; Jackson, IJ; McKie, L; Morgan, JE; West, K1
Beutler, B; Chang, B; Cheung, D; Du, X; Gong, X; Liu, H; Park, A; Wang, M; Xia, CH; Yang, Y1
Hyde, DR; Vihtelic, TS1

Other Studies

13 other study(ies) available for ethylnitrosourea and Retinal Degeneration

ArticleYear
Leaves of Acer palmatum thumb. Rescues N-ethyl-N-nitrosourea (ENU)-Induced retinal degeneration in mice.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Mar-15, Volume: 42

    Topics: Acer; Administration, Oral; Animals; Disease Models, Animal; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Injections, Intraperitoneal; Male; Mice, Inbred ICR; Nestin; Plant Extracts; Plant Leaves; Plants, Medicinal; Protective Agents; Retina; Retinal Degeneration; Rod Opsins

2018
A novel mutation in Prph2, a gene regulated by Nr2e3, causes retinal degeneration and outer-segment defects similar to Nr2e3 ( rd7/rd7 ) retinas.
    Mammalian genome : official journal of the International Mammalian Genome Society, 2008, Volume: 19, Issue:9

    Topics: Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; DNA Primers; Ethylnitrosourea; Female; Heterozygote; Homozygote; Intermediate Filament Proteins; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Orphan Nuclear Receptors; Peripherins; Receptors, Cytoplasmic and Nuclear; Retinal Degeneration; RNA, Messenger; Rod Cell Outer Segment

2008
Severe retinal degeneration caused by a novel rhodopsin mutation.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:2

    Topics: Animals; Base Sequence; Blotting, Western; DNA Mutational Analysis; Electroretinography; Ethylnitrosourea; Genes, Dominant; Genome-Wide Association Study; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Molecular Sequence Data; Mutagenesis; Ophthalmoscopy; Phenotype; Photoreceptor Cells, Vertebrate; Point Mutation; Protein Structure, Secondary; Retinal Degeneration; Rhodopsin

2010
Photoreceptor degeneration, azoospermia, leukoencephalopathy, and abnormal RPE cell function in mice expressing an early stop mutation in CLCN2.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:6

    Topics: Animals; Azoospermia; Blotting, Western; Brain; Chloride Channels; CLC-2 Chloride Channels; Codon, Nonsense; Electroretinography; Ethylnitrosourea; Female; Genome-Wide Association Study; Leukoencephalopathies; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutagenesis; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Retinal Pigment Epithelium

2010
A monogenic dominant mutation in Rom1 generated by N-ethyl-N-nitrosourea mutagenesis causes retinal degeneration in mice.
    Molecular vision, 2010, Mar-10, Volume: 16

    Topics: Animals; Base Sequence; DNA Mutational Analysis; Electroretinography; Ethylnitrosourea; Eye Proteins; Fundus Oculi; Gene Expression Regulation; Genes, Dominant; Haplotypes; Immunohistochemistry; Intermediate Filament Proteins; Male; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Molecular Sequence Data; Mutagenesis; Mutation; Nerve Tissue Proteins; Peripherins; Phenotype; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Tetraspanins

2010
An ENU-induced mutation in the Mertk gene (Mertknmf12) leads to a slow form of retinal degeneration.
    Investigative ophthalmology & visual science, 2011, Jul-01, Volume: 52, Issue:7

    Topics: Animals; Blotting, Western; c-Mer Tyrosine Kinase; Cell Death; Disease Models, Animal; Disease Progression; DNA; Electroretinography; Ethylnitrosourea; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mutation; Ophthalmoscopy; Phenotype; Photoreceptor Cells, Vertebrate; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Retina; Retinal Degeneration; Tumor Necrosis Factor-alpha

2011
Retinal degeneration induced in adult mice by a single intraperitoneal injection of N-ethyl-N-nitrosourea.
    Toxicologic pathology, 2011, Volume: 39, Issue:4

    Topics: Animals; Apoptosis; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; In Situ Nick-End Labeling; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Photoreceptor Cells, Vertebrate; Retina; Retinal Degeneration

2011
Translational vision research models program.
    Advances in experimental medicine and biology, 2012, Volume: 723

    Topics: Alkylating Agents; Animals; Chromosome Mapping; Cyclic Nucleotide Phosphodiesterases, Type 6; Disease Models, Animal; DNA Mutational Analysis; Ethylnitrosourea; Eye Proteins; Humans; Mice; Mice, Inbred C57BL; Mutagenesis; Retinal Degeneration; Rhodopsin; Translational Research, Biomedical

2012
Two zebrafish mutants, ebony and ivory, uncover benefits of neighborhood on photoreceptor survival.
    Journal of neurobiology, 2003, Volume: 57, Issue:3

    Topics: Alkylating Agents; Animals; Apoptosis; Blindness; Cell Communication; Chimera; Ethylnitrosourea; Immunohistochemistry; In Situ Nick-End Labeling; Mutation; Photoreceptor Cells; Retinal Degeneration; Zebrafish

2003
ENU-induced late-onset night blindness associated with rod photoreceptor cell degeneration in zebrafish.
    Mechanisms of ageing and development, 2003, Volume: 124, Issue:10-12

    Topics: Animals; Behavior, Animal; Electroretinography; Escape Reaction; Ethylnitrosourea; Female; Genes, Dominant; Homozygote; Male; Mutation; Night Blindness; Retina; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Vision, Ocular; Zebrafish

2003
Genotype-phenotype correlation of mouse pde6b mutations.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:9

    Topics: Alkylating Agents; Alleles; Animals; Cyclic Nucleotide Phosphodiesterases, Type 6; Disease Models, Animal; Disease Progression; DNA Mutational Analysis; Electrophoresis, Capillary; Ethylnitrosourea; Female; Genotype; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mutation; Phenotype; Phosphoric Diester Hydrolases; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Visual Acuity

2005
Characterization of mouse mutants with abnormal RPE cells.
    Advances in experimental medicine and biology, 2006, Volume: 572

    Topics: Animals; Cell Line; Disease Models, Animal; Ethylnitrosourea; Female; Heterozygote; Homozygote; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Mutation; Pigment Epithelium of Eye; Retinal Degeneration; Time Factors

2006
Zebrafish mutagenesis yields eye morphological mutants with retinal and lens defects.
    Vision research, 2002, Volume: 42, Issue:4

    Topics: Animals; Apoptosis; Ethylnitrosourea; Eye; Eye Color; Eye Diseases; Immunohistochemistry; Lens, Crystalline; Models, Animal; Mutagenesis; Retina; Retinal Degeneration; Zebrafish

2002