ethylnitrosourea has been researched along with Pregnancy in 340 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 217 (63.82) | 18.7374 |
| 1990's | 65 (19.12) | 18.2507 |
| 2000's | 46 (13.53) | 29.6817 |
| 2010's | 12 (3.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, FC; Conway, AJ; Curtis, DJ; Fullinfaw, RO; Jane, SM; Kile, BT | 1 |
| Chang, C; Hsu, YH; Jang, T; Lin, CY; Lin, MH; Recht, L; Siow, TY; Tung, YY | 1 |
| Alexandrov, VA; Baranenko, DA; Bespalov, VG; Kostikova, VА; Vysochina, GI | 1 |
| Fleming, C; McKerlie, C; Ottaviani, P; Yildiz, C | 1 |
| Babu, PP; Challa, S; Panigrahi, M; Sareddy, GR | 1 |
| Bando, Y; Izumi, K; Kaneda, S; Nakai, T; Ogawa, H; Ohnishi, T; Shiota, H; Takahashi, T; Takizawa, T; Tsuchigauchi, T; Uehara, H | 1 |
| Doblas, S; Garteiser, P; He, T; Herlea, O; Lupu, F; Saunders, D; Silasi-Mansat, R; Smith, N; Towner, RA; Watanabe, Y | 1 |
| Busby, ER; Isaac, ER; Sherwood, NM; Wilson, MD; Wu, S | 1 |
| Donovan, P; Smith, G | 1 |
| Dasenbrock, C; Ernst, H; Hansen, V; Streckert, J; Taugner, F; Tillmann, T; Zhou, Y | 1 |
| Dobrovolsky, VN; Ferguson, SA; Heflich, RH | 1 |
| Behan, NA; Kawata, A; Macfarlane, AJ; Swayne, BG; Wade, MG; Williams, A; Yauk, CL | 1 |
| Brown, FC; Collinge, JE; Curtis, DJ; Jane, SM; Kile, BT; Rank, G; Scott, N; Vadolas, J; Vickaryous, N; Whitelaw, E; Whitelaw, N | 1 |
| Baumgarner, KM; Cramer, MJ; Garner, JP; Justice, MJ; Lo, CL; Lossie, AC | 1 |
| Grdina, DJ; Li, JJ; Mauceri, HJ; Miller, RC; Murley, JS; Sutton, HG; Thirman, MJ; Weichselbaum, RR; Woloschak, GE | 1 |
| Doi, K; Ejiri, N; Katayama, K; Nakayama, H; Takai, H; Ueno, M; Uetsuka, K | 1 |
| Doi, K; Katayama, K; Nakayama, H; Ueno, M; Yamauchi, H | 2 |
| Claij, N; Dekker, M; Jansen, L; te Riele, H; van der Wal, A | 1 |
| Eppig, J; Hartford, SA; Libby, BJ; Munroe, RJ; O'Brien, M; Pendola, JK; Reinholdt, LG; Schimenti, JC; Schimenti, KJ; Ward, JO; Wilson, LA | 1 |
| Bielas, JH; Heddle, JA | 1 |
| Hu, JG; Kamata, M; Kawakami, E; Kikuchi-Horie, K; Nakagawa, H; Ohara, K; Oyanagi, K; Wada, M; Watabe, K | 1 |
| Jang, T; Litofsky, NS; Recht, LD; Ross, AH; Smith, TW | 1 |
| Zhang, YF; Zhang, ZY | 1 |
| Chen, T; Mei, N; Slikker, W | 1 |
| Li, HD; Liu, J; Mao, HH; Shao, YX; Tang, D; Wu, BJ; Xue, ZF | 1 |
| Anisimov, VN; Beniashvili, DS | 1 |
| Jang, T; Litofsky, NS; Low, HP; Matuasevic, Z; Recht, LD; Ross, AH; Salmonsen, R; Savarese, TM | 1 |
| Chen, T; Heflich, RH; Mei, N; Moore, MM | 1 |
| Demant, P; Horlings, H | 1 |
| Simmens, SJ; Zook, BC | 2 |
| Fernández-Valdivia, R; Metzker, ML; Pai, S; Schumacher, A; Zhang, Y | 1 |
| Chatterjee, B; Leatherbury, L; Lo, CW; Lucas, J; Pappas, MA; Rosenthal, J; Shen, Y; Siegfried, B; Svenson, K; Wessels, A; Yu, Q | 1 |
| Casaccia-Bonnefil, P; Garcia-Verdugo, JM; Gil-Perotin, S; Li, J; Marin-Husstege, M; Roussel, MF; Soriano-Navarro, M; Zindy, F | 1 |
| Duong, T; Jang, T; Kim, S; Lapointe, D; Litofsky, NS; Low, HP; Recht, L; Ross, AH; Savarese, T; Vogel, H; Weimann, JM | 1 |
| Anderson, KV; Caspary, T | 1 |
| Babu, PP; Bhaskara, VK; Sundaram, C | 1 |
| Gondo, Y; Hosoya, M; Kaneda, H; Kaneko, S; Kobayashi, K; Masuya, H; Miura, I; Nagano, J; Noda, T; Okagaki, Y; Sagai, T; Sakuraba, Y; Sakurai, N; Sezutsu, H; Shimizu, A; Shiroishi, T; Sumiyama, K; Wakana, S; Yokoyama, H | 1 |
| Donovan, PJ; Dove, LF; Klose, J; Powell, DA; Smith, GT | 1 |
| Chen, YH; Chen, YT; Cheng, CF; Huang, CC; Hung, SI; Kao, HJ; Kikuchi, T; Millington, D; Wu, JY | 1 |
| Bulnes, S; Lafuente, JV | 1 |
| Dunnick, JK; Foley, J; Horton, JL; Kissling, GE; Malarkey, DE; Morrison, JP; Satoh, H | 1 |
| Debien, E; Gratas, C; Hervouet, E; Homma, T; Le Cabellec, MT; Meflah, K; Menanteau, J; Olivier, C; Pedelaborde, F; Pouliquen, D; Vallette, FM | 1 |
| Fox, RR; Hard, GC | 2 |
| Basler, A; Röhrborn, G; Theiss, I | 1 |
| McLaughlin, PJ; Zagon, IS | 2 |
| Raĭkhlin, NT; Timoshenko, IV; Turusov, VS | 1 |
| Bedigian, HG; Fox, RR; Meier, H; Pottathil, R | 1 |
| Hara, H; Kutsukake, F; Miyao, M; Moriki, T; Yamane, T | 1 |
| Perez-Polo, JR; Vinores, SA | 2 |
| Kroh, H | 2 |
| Miller, RK | 1 |
| Wrba, H | 1 |
| Kleihues, P; Rajewsky, MF | 1 |
| Enomoto, T; Hata, S; Kanzaki, T; Kimura, S; Kusafuka, T; Miyamoto, S; Nomura, T; Shibata, K; Sobue, K; Tanaka, H | 1 |
| Hara, H; Hashimoto, M; Hiroi, M; Matsusaki, K; Moriki, T; Yamane, T | 1 |
| Aleksandrov, VA; Bespalov, VG | 3 |
| Iablonovskaia, LIa; Khalanskiĭ, AS; Kondakova, LI; Morozov, IuE | 1 |
| Emmelot, P; Oomen, LC; van der Valk, MA | 1 |
| Aleksandrov, VA; Anisimov, VN; Bespalov, VG; Khavinson, VKh; Morozov, VG | 1 |
| Ito, A; Kawashima, K; Naito, M; Naito, Y; Watanabe, H | 1 |
| Ird, EA; Smirnova, IO | 2 |
| Das, GD; Houle, JD | 1 |
| Hayashi, K | 1 |
| Blasberg, RG; Fenstermacher, JD; Groothuis, D; Horowitz, M; Kobayashi, T; Molnar, P; Rice, JM | 2 |
| Bridle, TM; Dreosti, IE; McMichael, AJ | 1 |
| D'Ambrosio, SM; Gibson-D'Ambrosio, RE; Leong, Y | 1 |
| Alvarez, T; Cardesa, A; Llanes, F; Ludeña, MD; Merchan, J; Mohr, U | 1 |
| Abdel-Galil, AM; Dutter, A; Hacker-Rieder, A; Wrba, H | 1 |
| Erickson, LC; Kohn, KW; Sariban, E | 1 |
| Lang, R | 1 |
| Camp, RC; Capen, CC; Koestner, A; Vinores, SA | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N; Taomoto, K | 1 |
| Ikuta, F; Oyanagi, K; Yoshida, Y | 2 |
| Concetti, HF; Kitagawa, T; Sugano, H; Tsuchiya, E | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N | 2 |
| Kolodin, VI; P''rvanova, LG | 1 |
| Nomura, T | 2 |
| Demant, P; Emmelot, P; Hart, AA; Oomen, LC | 1 |
| Eckhardt, K; Gocke, E; King, MT; Wild, D | 1 |
| Rajewsky, MF | 1 |
| Müller, R; Rajewsky, MF | 1 |
| Dutter, A; Hacker-Rieder, A; Wrba, H | 1 |
| Erickson, LC; Zlotogorski, C | 1 |
| Narasaki, M; Ogawa, K; Tomoyori, T; Yokokawa, K | 1 |
| Cervós-Navarro, J; Kroh, H | 1 |
| Ikeda, T; Kohno, S; Maeda, H; Matsuo, T; Tashiro, T | 1 |
| Cravioto, H; Ransohoff, J; Yoshida, J | 1 |
| Giordana, MT; Mauro, A; Schiffer, D | 1 |
| Johnson, FM; Lewis, SE | 1 |
| Bedigian, HG; Crary, DD; Fox, RR; Meier, H | 1 |
| London, WT; Palmer, AE; Rice, JM; Sly, DL; Williams, GM | 1 |
| Koestner, A; Vinores, SA | 1 |
| Alvira, MM; Mandybur, TI | 1 |
| Enzan, H; Hara, H; Kutsukake, F; Miyao, M; Moriki, T; Yamane, T | 1 |
| Fiebig, HH; Schmähl, D; Strobel, H | 1 |
| Anderson, LM; Budinger, JM; Last-Barney, K | 1 |
| Kalter, H; Ormsby, I; Warkany, J | 1 |
| Ivankovic, S | 2 |
| Kalter, H; Mandybur, TI; Ormsby, I; Warkany, J | 1 |
| Chang, MJ; Hart, RW; Koestner, A | 1 |
| Kauffman, SL | 2 |
| Adamczewska-Goncerzewicz, Z; Mularek, O; Wender, M; Zórawski, A | 1 |
| Takeda, Z; Urano, Y | 1 |
| Alexandrov, VA; Anisimov, VN; Napalkov, NP | 1 |
| Bressler, JP; Cole, R; de Vellis, J | 1 |
| Ito, A; Naito, M; Naito, Y | 1 |
| Cabral, JR; Likhachev, AJ; Ponomarkov, V; Tomatis, L | 1 |
| Bock, E; Haugen, A; Laerum, OD | 1 |
| Rice, JM | 1 |
| Bruno, F; Giordana, MT; Mauro, A; Paoletti, P; Pezzotta, S; Racagni, G; Schiffer, D | 1 |
| Conley, FK | 1 |
| Kauffman, SL; Sato, T | 1 |
| Diwan, BA; Rice, JM | 1 |
| Perin, A; Sessa, A; Tunici, P | 1 |
| Abraham, SK | 1 |
| Faustman, EM; Kidney, JK | 1 |
| Ashby, J; Morrison, V; Tinwell, H | 1 |
| Demant, P; Fijneman, RJ | 1 |
| Hara, T; Horiya, N; Matsuda, H; Murota, T; Shibuya, T | 1 |
| Nagao, T; Sato, M; Takashima, H; Wada, A | 1 |
| Shima, A; Shimada, A | 1 |
| Coca, S; Oya, S; Vaquero, J; Zurita, M | 1 |
| Cabrera, MM; Morales, C; Oya, S; Vaquero, J; Zurita, M | 1 |
| Alcaraz-Zubeldia, MM; Barroso-Moguel, R; Galván-Arzate, S; Méndez-Armenta, M; Ríos, C; Villeda-Hernández, J | 1 |
| Morales, C; Oya, S; Vaquero, J; Zurita, M | 1 |
| Broglia, E; Perin, A; Sessa, A; Terreni, MR | 2 |
| Hino, O; Knudson, AG; Mitani, H | 1 |
| Carpenter, DA; Long, CL; Rinchik, EM | 1 |
| Harbaugh, SW; Palmer, AE; Rehm, S; Rice, JM | 1 |
| Brüstle, O; Höll, T; Kleihues, P; Petersen, I; Plate, KH; Radner, H; Wiestler, OD | 1 |
| Carpenter, DA; Rinchik, EM | 1 |
| Alexandrov, VA; Anisimov, VN; Bespalov, VG; Khavinson, VKh; Morozov, VG | 1 |
| Alexandrov, VA; Bespalov, VG; Petrov, AS; Troyan, DN | 1 |
| Diwan, BA; Rehm, S; Rice, JM | 1 |
| Imai, K; Marumo, H; Nagao, T; Sato, M; Shibuya, T | 1 |
| Aizawa, S; Ishikawa, T; Nakatsuru, Y; Oda, H; Shimizu, S; Tsurutani, N; Zhang, S | 1 |
| Ashby, J; Lefevre, P; Tinwell, H; Williams, CV | 1 |
| Bederson, JB; Germano, IM; Segal, DH | 1 |
| Fujikawa, K; Nagao, T | 1 |
| Hiasa, Y; Konishi, N; Nakamura, M; Sakaki, T; Tsunoda, S; Tsuzuki, T; Yabuno, T | 1 |
| Darcel, F; Jallet, P; Le Jeune, JJ; Pouliquen, D; Rousseau, V | 1 |
| Hayashi, S; Ikuta, F; Kakita, A; Kawasaki, K; Oyanagi, K; Yamada, M | 1 |
| Fukuda, T; Hino, O; Konishi, Y; Mitani, H; Tsutsumi, M | 1 |
| Inokuchi, T; Kaidoh, T; Shigemori, M; Yoshimura, F | 1 |
| Blaivas, M; Kish, P; Muraszko, KM; Ross, DA; Strawderman, M | 1 |
| Boncinelli, E; Canal, N; Feltri, ML; Nemni, R; Pardini, CL; Previtali, SC; Quattrini, A; Wrabetz, L | 1 |
| Donovan, PJ; Smith, GT | 1 |
| Donovan, PJ | 1 |
| Calloni, A; Perin, A; Rabellotti, E; Sessa, A; Tunici, P | 1 |
| Adey, WR; Byus, CV; Cain, CD; Haggren, W; Higgins, RJ; Jones, RA; Kean, CJ; Kuster, N; MacMurray, A; Phillips, JL; Stagg, RB; Zimmerman, G | 1 |
| Groothuis, DR; Lapin, GD; Molnar, P; Schlageter, KE | 1 |
| Anderson, LM; Buzard, GS; Devor, DE; Enomoto, T; Perantoni, AO; Rice, JM | 1 |
| Désy, M; Devaux, C; Franco, E; Gaboury, L; Mandeville, R; Mercier, G; Paris-Nadon, L; Rocheleau, N; Sidrac-Ghali, S | 1 |
| Adey, WR; Byus, CV; Cain, CD; Higgins, RJ; Jones, RA; Kean, CJ; Kuster, N; MacMurray, A; Stagg, RB; Zimmerman, G | 1 |
| Doi, K; Ishigami, N; Katayama, K; Nakayama, H; Uetsuka, K | 2 |
| Doi, K; Ishigami, N; Katayama, K; Kiatipattanasakul, W; Nakayama, H; Ohtsuka, R; Suzuki, M | 1 |
| Anisimov, VN; Baturin, DA; Beniashvili, DS; Benjamin, S | 1 |
| Canonne-Hergaux, F; Gauthier, S; Gros, P; Justice, MJ; Kibar, Z; Underhill, DA | 1 |
| Albertini, RJ; Bauer, MJ; Judice, SA; Shi, X; Sussman, HE; Walker, VE | 1 |
| Demant, P; Fijneman, RJ; Hart, AA; Tripodis, N | 1 |
| D'Sa, C; Klocke, BJ; Leonard, JR; Roth, KA | 1 |
| Beier, DR; Bronson, RT; Herron, BJ; Justice, MJ; Liu, S; Lu, W; McDonald, JD; Peters, H; Rao, C | 1 |
| Rembao, D; Reyes, S; Sotelo, J | 1 |
| Ciccalese, R; De Felici, M; Iona, S; Klinger, FG; Nunziata, A; Sisti, R | 1 |
| Chang, MJ; Koestner, A; Webb, TE | 1 |
| Bannasch, P; Mayer, D; Venske, G | 1 |
| Kolodin, VI; Okulov, VB | 1 |
| Matsumoto, S; Tanaka, M | 1 |
| Matsumoto, S; Tamaki, N; Taomoto, K | 1 |
| Fujiwara, K; Matsumoto, S; Tamaki, N; Taomoto, K | 2 |
| Beniashvili, DSh; Dimant, IN | 2 |
| London, WT; Palmer, AE; Rice, JM; Sly, DL | 1 |
| Hadjiolov, D; Venkov, L | 1 |
| Love, LA; Pelfrene, AF | 1 |
| Kriegel, H; Schmahl, W | 2 |
| Lantos, PL | 3 |
| Hänichen, T; Stavrou, D | 1 |
| Giordana, MT; Paoletti, P; Pezzotta, S; Schiffer, D | 2 |
| Rustia, M; Schenken, J | 1 |
| Cox, DJ; Lantos, PL; Pilkington, GJ | 1 |
| Ponomarkov, V; Tomatis, L; Turusov, V | 1 |
| Dahme, E; Schröder, B; Stavrou, D | 1 |
| Pfeiffer, SE; Ramadan, MA; Wechsler, W | 1 |
| Cravioto, H; Yoshida, J | 1 |
| Claisse, PJ; Roscoe, JP | 2 |
| Claisse, PJ; Lantos, PL; Roscoe, JP | 1 |
| Haugen, A; Laerum, OD | 2 |
| Das, GD; Pfaffenroth, MJ | 1 |
| Lehnguth, C; Osske, G; Schneider, J; Warzok, R | 1 |
| Mookenthottathil, T | 1 |
| Cravioto, H; Morantz, RA; Shain, W | 1 |
| Rice, JM; Vesselinovitch, SD; Wechsler, W | 1 |
| Mihailovich, N; Rao, KV; Vesselinovitch, SD | 1 |
| Pötzsch, HD; Schneider, J; Scholtze, P; Thust, R; Warzok, R | 1 |
| Jänisch, W; Scholtze, P; Schreiber, D; Warzok, R | 1 |
| Lantos, PL; Pilkington, GJ | 4 |
| Beniashvili, DSh | 1 |
| Hellström, I; Hellström, KE; Spence, AM; Sullivan, K; Van Belle, G; Wahlström, T | 1 |
| Aleksandrov, VA | 1 |
| Hata, T; Kawakubo, Y; Komiyama, K; Nishiyama, Y; Umezawa, I | 1 |
| Das, GD; Hallas, BH | 1 |
| Mollner, T; Munhall, A; Rossi, L; Shubik, P | 1 |
| Rustia, M | 2 |
| Bruno, F; Giordana, MT; Paoletti, P; Pezzotta, S; Racagni, G; Schiffer, D | 1 |
| Haugen, A; Matre, R | 1 |
| Taomoto, K | 2 |
| Kolodin, VI; Likhachev, AIa; Napalkov, NP; Tomatis, L | 1 |
| Adamczewska-Goncerzewicz, Z; Mularek, O; Pancrac, J; Sedzik, J; Wender, M | 1 |
| Kageyama, N; Kameyama, Y; Kobayashi, T; Umemura, S; Yoshida, J | 1 |
| Kolodin, VI | 1 |
| Giordana, MT; Lechner, C; Paoletti, P; Pezzotta, S; Schiffer, D | 1 |
| Aleksandrov, VA; Schreiber, D | 1 |
| Gerlach, H; Peschel, B; Rath, FW; Schreiber, D; Wessel, H | 1 |
| Buncher, CR; Mandybur, TI; Ormsby, I | 1 |
| Golub', NI; Shabad, LM | 1 |
| Mularek, O; Piechowski, A; Sedzik, J; Talkowska, D; Wender, M | 1 |
| Habs, M; Schmähl, D | 1 |
| Alexandrov, VA | 1 |
| Thust, R | 1 |
| Koka, M; Mihailovich, N; Rao, KV; Rice, JM; Vesselinovitch, SD | 1 |
| Kolodin, VI; Lihachev, AIa; Napalkov, NP; Tomatis, L | 1 |
| Balakhonov, AV | 1 |
| Conliffe, M; Dove, L; Friedman, R; Gipson, TG; Martin, WJ; Rice, JM | 1 |
| Likhachev, AIa | 1 |
| Cox, DJ; Lantos, PL | 1 |
| Leipolz, S | 1 |
| Abe, H; Ito, T; Kobayashi, N; Tashiro, K; Tsuru, M | 1 |
| Clendenon, N; Denlinger, R; Gordon, WA; Swenberg, JA | 1 |
| Diwan, BA; Fox, RR; Meier, H | 1 |
| Herschman, H; Rose, S; Sanborn, S; Stahn, R; West, G | 1 |
| Zeller, WJ | 1 |
| Laerum, OD; Rajewsky, MF | 1 |
| Berg, H; Graw, J; Ivankovic, S; Schmähl, D | 1 |
| Kalter, H; Mandybur, TI; Warkany, J | 1 |
| Aleksandrov, VA; Bespalov, VG; Petrov, AS; Troian, DN | 2 |
| Aleksandrov, VA; Bespalov, VG; Davydov, VV; Iaremenko, KV; Lazareva, NL; Limarenko, AIu; Petrov, AS; Slepian, LI; Troian, DN | 1 |
| Dietze, EC; Giometti, CS; Hammock, BD; Nourooz-Zadeh, J; Tollaksen, SL; Winder, BS | 1 |
| Catalano, A; Huang, PH | 1 |
| Aguzzi, A; Basilico, C; Brüstle, O; Kleihues, P; Talarico, D; Wiestler, OD | 1 |
| Arias, A; Coca, S; Morales, C; Oya, S; Vaquero, J; Zurita, M | 1 |
| Giordana, MT; Migheli, A; Mocellini, C; Schiffer, D; Villare, F | 1 |
| Arias, A; Coca, S; Morales, C; Moreno, M; Oya, S; Vaquero, J; Zurita, M | 1 |
| Kang, H; Maekawa, A; Nagase, S; Shumiya, S; Usuki, S | 1 |
| Dayan, A; Purves, D | 1 |
| Alexandrov, VA; Bespalov, VG; Boone, CW; Kelloff, GJ; Malone, WF | 1 |
| Bilzer, T; Reifenberger, G; Vogeley, KT; Wechsler, W | 1 |
| Cavalla, P; Giordana, MT; Schiffer, D; Vigliani, MC | 1 |
| Leierseder-Bauer, M; Luz, A; Neuhäuser-Klaus, A; Schmahl, W | 2 |
| Bangham, JW; Russell, LB | 1 |
| Anderson, LM; Rehm, S; Rice, JM; Riggs, CW; Ward, JM | 1 |
| Golenko, OD; Miasishcheva, NV; Ryzhova, NI | 3 |
| Hasgekar, N; Lalitharao, VS; Murugesan, S; Patel, MC; Ramanathan, P; Samuel, AM | 1 |
| Diwan, BA; Konishi, N; Ward, JM | 1 |
| Dreyhaupt, T; Mennel, HD | 1 |
| Imanishi, H; Matsumoto, K; Ohta, T; Sasaki, YF; Shirasu, Y; Tutikawa, K; Watanabe, M | 1 |
| Huang, Y; Tao, H; Yang, G | 1 |
| Palmer, KC | 1 |
| Giaccone, G; Giordana, MT; Mauro, A; Migheli, A; Pezzotta, S; Schiffer, D | 1 |
| Beniashvili, DSh; Zedginidze, TG | 1 |
| Rehm, S; Ward, JM | 1 |
| Cardesa, A; Mohr, U; Palacín, A; Ribalta, T; Von Schilling, B | 1 |
| Ohaki, Y | 1 |
| Hara, M; Kasuga, T; Nakamura, T | 1 |
| Campanile, G; Capurro, G; Cipolla, M; Muratore, O; Rossi, L; Varnier, OE | 1 |
| Donovan, PJ; Perantoni, AO; Rehm, S; Rice, JM | 1 |
| Koestner, A; Lovell, KL; Marushige, K; Okazaki, D; Raju, NR | 1 |
| Faustman, EM; Gage, D; Kirby, Z; Varnum, M | 1 |
| Abe, S; Hinokuma, K; Kumanishi, T; Nishiyama, A; Yamada, M; Yoshida, Y | 1 |
| Swenberg, JA; Walker, VE | 1 |
| Branstetter, DG; Budd, C; Conran, PB; Goldblatt, PJ; Stoner, GD | 2 |
| Ohnishi, M | 1 |
| Palencia, G; Perez, R; Rosas, N; Sotelo, J | 1 |
| Aguzzi, A; Burger, PC; Kleihues, P; Shibata, T | 1 |
| Diwan, BA; Ohshima, M; Rice, JM | 1 |
| Demant, P; Hart, AA; Oomen, LC; van der Valk, MA | 1 |
| Motoi, M; Ogawa, K; Yoshino, T | 2 |
| Hard, GC | 1 |
| Blount, MA; Ponder, BA; Winton, DJ | 1 |
| Nagao, T | 1 |
| Mennel, HD | 1 |
| Anderson, LM; Katyal, SL; Rehm, S; Rice, JM; Singh, G; ten Have-Opbroek, AA; Ward, JM | 1 |
| Aleksandrov, VA; Bespalov, VG; Khavinson, VKh; Morozov, VG | 2 |
| Cain, KT; Downing, DJ; Generoso, WM; Hughes, LA; Rutledge, JC | 1 |
| Cabral, R; Cardis, E; Tiutiunnik, NF; Tomatis, L; Turusov, VS | 1 |
| Perantoni, AO; Reed, CD; Rice, JM; Watatani, M; Wenk, ML | 1 |
| Schmahl, W; Wiggenhauser, A | 1 |
| Altena, B; Lens, PF; Nusse, R | 1 |
| Plendl, J; Reinöhl-Kompa, S; Schmahl, WG | 1 |
| Nielsen, IM | 1 |
| Imanishi, H; Moriya, M; Sasaki, YF; Sekiguchi, A; Shirasu, Y; Tutikawa, K; Watanabe, M | 1 |
| Lyon, MF; Renshaw, R | 1 |
| Hung, CF | 1 |
| Kokunai, T; Korosue, K; Matsumoto, S; Tamaki, N | 1 |
| Hellwig, D; Mennel, HD; Simon, H | 1 |
| Branstetter, DG; Conran, PB; Goldblatt, PJ; Schut, HA; Senitzer, D; Stoner, GD | 1 |
| Johnson, FM; Lovell, DP; Willis, DB | 1 |
| Carpenter, DA; Hitotsumachi, S; Russell, WL | 1 |
| Yoshino, T | 1 |
| Bock, E; Haglid, K; Haugen, A; Laerum, OD; Mørk, SJ; Rosengren, L | 1 |
| Abe, H; Allen, N; Clendenon, NR; Swenberg, JA | 1 |
9 review(s) available for ethylnitrosourea and Pregnancy
| Article | Year |
|---|---|
Uncovering the uncharacterized and unexpected: unbiased phenotype-driven screens in the mouse.
Topics: Alleles; Animals; Epigenesis, Genetic; Ethylnitrosourea; Female; Fertility; Immunity; Male; Mice; Morphogenesis; Mutagenicity Tests; Mutagens; Mutation; Phenotype; Pregnancy; Proteins | 2006 |
Nerve growth factor and neural oncology.
Topics: Animals; Cell Differentiation; Cells, Cultured; DNA; Ethylnitrosourea; Female; Ganglia; Gestational Age; Glioma; Humans; Neoplasms, Nerve Tissue; Nerve Growth Factors; Nervous System Neoplasms; Neuroblastoma; Neuroglia; Neurons; Pheochromocytoma; Pregnancy; Prenatal Exposure Delayed Effects | 1983 |
Perinatal toxicology: its recognition and fundamentals.
Topics: Animals; Behavior; Blastocyst; Cadmium; Cell Differentiation; Diethylstilbestrol; Ethylnitrosourea; Female; Fetus; Humans; Immunity; Neoplasms; Nervous System; Placenta; Pregnancy; Reproduction; Teratogens; Trophoblasts; Vaginal Neoplasms | 1983 |
Chemical neuro-oncogenesis: role of structural DNA modifications, DNA repair and neural target cell population.
Topics: Alkylating Agents; Alkylation; Animals; Brain; Brain Neoplasms; Carcinogens; Cell Count; DNA; DNA Repair; Ethylnitrosourea; Female; Fetal Diseases; Humans; Methylnitrosourea; Pregnancy | 1984 |
N-nitroso-N-ethylurea.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Ethylnitrosourea; Female; Humans; Mutagens; Nitrosourea Compounds; Pregnancy; Teratogens | 1978 |
Transplacental and neonatal induction of neurogenic tumors in mice: comparison with related species and with human pediatric neoplasms.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Child; Ethylnitrosourea; Female; Humans; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Species Specificity | 1979 |
Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis.
Topics: Animals; Animals, Newborn; Carcinogens; Ethylnitrosourea; Female; Gestational Age; Harderian Gland; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ovarian Neoplasms; Pregnancy; Risk; Stomach Neoplasms | 1979 |
Congenital malformations as a consequence of parental exposure to radiation and chemicals in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Dioxins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethylnitrosourea; Fathers; Female; Gestational Age; Humans; Male; Mice; Mice, Inbred ICR; Mutation; Oocytes; Pregnancy; Prenatal Exposure Delayed Effects; Spermatozoa; Urethane; Vietnam | 1989 |
Development of nitrosourea-induced brain tumours--with a special note on changes occurring during latency.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasm Invasiveness; Neoplastic Stem Cells; Phenotype; Precancerous Conditions; Pregnancy; Time Factors | 1986 |
331 other study(ies) available for ethylnitrosourea and Pregnancy
| Article | Year |
|---|---|
A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen.
Topics: Anemia, Hypochromic; Animals; Base Sequence; Biosynthetic Pathways; Coproporphyria, Hereditary; Coproporphyrinogen Oxidase; Disease Models, Animal; Ethylnitrosourea; Fasting; Feces; Female; Heme; Male; Mice, Mutant Strains; Mutagenesis; Mutation; Phenobarbital; Phenotype; Pregnancy | 2017 |
Visualization of rodent brain tumor angiogenesis and effects of antiangiogenic treatment using 3D ΔR2-μMRA.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Corpus Striatum; Ethylnitrosourea; Female; Glioma; Imaging, Three-Dimensional; Immunoenzyme Techniques; Magnetic Resonance Angiography; Neoplasm Transplantation; Neovascularization, Pathologic; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2013 |
The inhibiting activity of meadowsweet extract on neurocarcinogenesis induced transplacentally in rats by ethylnitrosourea.
Topics: Animals; Central Nervous System Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Filipendula; Kidney Neoplasms; Male; Maternal-Fetal Exchange; Plant Extracts; Pregnancy; Prenatal Exposure Delayed Effects | 2017 |
Fresh and frozen-thawed sperm quality, nuclear DNA integrity, invitro fertility, embryo development, and live-born offspring of N-ethyl-N-nitrosourea (ENU) mice.
Topics: Acrosome; Animals; Blastocyst; Cell Size; Cell Survival; Cryopreservation; DNA Fragmentation; Embryo Culture Techniques; Embryo Transfer; Embryonic Development; Ethylnitrosourea; Female; Fertility; Fertilization in Vitro; Male; Mice; Oocytes; Pregnancy; Semen Preservation; Sperm Motility; Spermatozoa | 2008 |
Wnt/beta-catenin/Tcf signaling pathway activation in malignant progression of rat gliomas induced by transplacental N-ethyl-N-nitrosourea exposure.
Topics: Animals; beta Catenin; DNA-Binding Proteins; Ethylnitrosourea; Female; Glioma; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-myc; Rats; Signal Transduction; Transcription Factor 4; Transcription Factors; Wnt Proteins | 2009 |
Low susceptibility to N-ethyl-N-nitrosourea-induced transplacental carcinogenesis in Long-Evans Cinnamon (LEC) rats.
Topics: Animals; Base Sequence; Carcinogens; Ethylnitrosourea; Female; Liver; Lung Neoplasms; Male; Maternal-Fetal Exchange; Metallothionein; Nervous System Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Pregnancy; Rats; Rats, Inbred F344; Rats, Inbred LEC; Rats, Long-Evans; RNA, Messenger; Species Specificity | 2009 |
In vivo detection of inducible nitric oxide synthase in rodent gliomas.
Topics: Albumins; Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Ethylnitrosourea; Female; Fluorescence; Gadolinium DTPA; Glioma; Immunohistochemistry; Male; Microscopy, Electron, Transmission; Molecular Probe Techniques; Neoplasm Transplantation; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Inbred F344 | 2010 |
Disruption of the single copy gonadotropin-releasing hormone receptor in mice by gene trap: severe reduction of reproductive organs and functions in developing and adult mice.
Topics: Alkylating Agents; Animals; Ethylnitrosourea; Female; Genes, Reporter; Gonadotropin-Releasing Hormone; Hypogonadism; Kisspeptins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovary; Phenotype; Pregnancy; Proteins; Receptors, G-Protein-Coupled; Receptors, Kisspeptin-1; Receptors, LHRH; Testis | 2010 |
Mutagenicity of N-ethyl-N-nitrosourea, N-methyl-N-nitrosourea, methyl methanesulfonate and ethyl methanesulfonate in the developing Syrian hamster fetus.
Topics: Animals; Cricetinae; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Mesocricetus; Methyl Methanesulfonate; Methylnitrosourea; Mutagenicity Tests; Mutagens; Pregnancy; Pregnancy, Animal | 2010 |
Indication of cocarcinogenic potential of chronic UMTS-modulated radiofrequency exposure in an ethylnitrosourea mouse model.
Topics: Animals; Body Weight; Cell Phone; Disease Models, Animal; Electromagnetic Fields; Ethylnitrosourea; Female; Lung; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Radiation-Induced; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors | 2010 |
N-nitroso-N-ethylurea.
Topics: Alkylating Agents; Animals; Animals, Newborn; Carcinogenicity Tests; Carcinogens; Cricetinae; Environmental Exposure; Ethylnitrosourea; Female; Government Regulation; Guidelines as Topic; Haplorhini; Humans; Male; Mice; Models, Biological; Pregnancy; Rats; United States | 2004 |
The frequency of Pig-a mutant red blood cells in rats exposed in utero to N-ethyl-N-nitrosourea.
Topics: Alkylating Agents; Animals; CD59 Antigens; Erythrocytes; Ethylnitrosourea; Female; Membrane Proteins; Mutagenicity Tests; Mutagens; Mutation; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Uterus | 2012 |
Investigating the effects of dietary folic acid on sperm count, DNA damage and mutation in Balb/c mice.
Topics: Animals; Dietary Supplements; DNA Damage; DNA Fragmentation; Ethylnitrosourea; Female; Folic Acid; Folic Acid Deficiency; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Mutagens; Mutation; Pregnancy; Sperm Count; Spermatozoa; Weaning | 2012 |
ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level.
Topics: Animals; beta-Globins; beta-Thalassemia; Codon; Codon, Nonsense; Disease Models, Animal; Erythrocyte Indices; Ethylnitrosourea; Exons; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Genetic Complementation Test; Genotype; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutagenesis; Mutagens; Polyadenylation; Pregnancy; Spleen | 2013 |
ENU mutagenesis reveals that Notchless homolog 1 (Drosophila) affects Cdkn1a and several members of the Wnt pathway during murine pre-implantation development.
Topics: Animals; Cyclin-Dependent Kinase Inhibitor p21; Embryonic Development; Ethylnitrosourea; Female; Gene Expression Regulation, Developmental; Mice; Microfilament Proteins; Mutagenesis; Mutation; Pregnancy; Pregnancy, Animal; Wnt Signaling Pathway | 2012 |
A manganese superoxide dismutase (SOD2)-mediated adaptive response.
Topics: Adaptation, Physiological; Alkylating Agents; Animals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Radiation; Ethylnitrosourea; Female; Genomic Instability; Humans; Mercaptoethylamines; Mice; Mice, Inbred C57BL; Pregnancy; Signal Transduction; Superoxide Dismutase | 2013 |
Ethylnitrosourea induces apoptosis and growth arrest in the trophoblastic cells of rat placenta.
Topics: Alkylating Agents; Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Cell Division; DNA Fragmentation; Embryonic and Fetal Development; Ethylnitrosourea; Female; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Organ Size; Placenta; Placentation; Pregnancy; Rats; Rats, Inbred F344; Teratogens; Trophoblasts; Tumor Suppressor Protein p53 | 2002 |
Ethylnitrosourea-induced apoptosis in primordial germ cells of the rat fetus.
Topics: Alkylating Agents; Animals; Apoptosis; DNA Fragmentation; Ethylnitrosourea; Female; Fetus; Germ Cells; Gonads; Male; Pregnancy; Rats; Rats, Inbred F344; Tumor Suppressor Protein p53 | 2002 |
DNA mismatch repair deficiency stimulates N-ethyl-N-nitrosourea-induced mutagenesis and lymphomagenesis.
Topics: Alkylating Agents; Animals; Base Pair Mismatch; DNA Repair; DNA-Binding Proteins; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Male; Mice; Mutagenesis; MutS Homolog 2 Protein; Pregnancy; Proto-Oncogene Proteins | 2003 |
Toward the genetics of mammalian reproduction: induction and mapping of gametogenesis mutants in mice.
Topics: Animals; Chromosome Mapping; Ethylnitrosourea; Female; Gametogenesis; Genotype; Infertility; Male; Meiosis; Mice; Mutagenesis; Mutagenicity Tests; Mutagens; Mutation; Oocytes; Phenotype; Pregnancy; Reproduction | 2003 |
Elevated mutagenesis and decreased DNA repair at a transgene are associated with proliferation but not apoptosis in p53-deficient cells.
Topics: Animals; Apoptosis; Base Sequence; Cell Cycle; Cell Division; Crosses, Genetic; DNA Primers; DNA Repair; Ethylnitrosourea; Female; Flow Cytometry; Genes, p53; Genotype; Homozygote; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis; Mutagens; Pregnancy; Tumor Suppressor Protein p53 | 2003 |
Distinctive expression of midkine in the repair period of rat brain during neurogenesis: immunohistochemical and immunoelectron microscopic observations.
Topics: Alkylating Agents; Animals; Brain Diseases; Carrier Proteins; Cell Cycle; Cell Division; Cytokines; Ethylnitrosourea; Female; Gene Expression Regulation, Developmental; Immunohistochemistry; Male; Midkine; Neocortex; Nerve Growth Factors; Nerve Regeneration; Neurons; Organogenesis; Pregnancy; Rats | 2004 |
Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis.
Topics: Animals; Biomarkers, Tumor; Brain Injuries; Brain Neoplasms; Carcinogens; Cell Lineage; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Intermediate Filament Proteins; Microscopy, Confocal; Nerve Tissue Proteins; Nestin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2004 |
[p16 protein expression in the transplacental induced brain tumor in rat].
Topics: Animals; Brain; Brain Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Male; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
N-ethyl-N-nitrosourea (ENU) increased brain mutations in prenatal and neonatal mice but not in the adults.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; DNA; DNA Mutational Analysis; Ethylnitrosourea; Female; Fetus; Male; Mice; Mice, Inbred C57BL; Mutagens; Pregnancy | 2004 |
Two kinds of ENU-induced scant hair mice and mapping of the mutant genes.
Topics: Alkylating Agents; Animals; Chromosome Mapping; Disease Models, Animal; Ethylnitrosourea; Female; Genes, Dominant; Genes, Recessive; Genomics; Genotype; Hair Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Mutant Strains; Mutagenesis; Phenotype; Pregnancy | 2004 |
Morphology of experimentally induced tumors of the sympathetic nervous system in rats.
Topics: Animals; Autonomic Nervous System Diseases; Ethylnitrosourea; Female; Ganglioneuroblastoma; Ganglioneuroma; Male; Nervous System Neoplasms; Neuroblastoma; Pregnancy; Rats | 2004 |
Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure.
Topics: ADP-Ribosylation Factors; Animals; Brain; Brain Neoplasms; Cell Differentiation; Cells, Cultured; Cerebral Ventricles; Corpus Striatum; Cyclin-Dependent Kinase Inhibitor p16; DNA Primers; Epidermal Growth Factor; Ethylnitrosourea; Female; Male; Membrane Proteins; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Suppressor Protein p14ARF | 2005 |
Age-dependent sensitivity of Big Blue transgenic mice to the mutagenicity of N-ethyl-N-nitrosourea (ENU) in liver.
Topics: Age Factors; Animals; Animals, Newborn; Base Sequence; DNA Primers; Ethylnitrosourea; Female; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagens; Pregnancy | 2005 |
Microarray analysis of genes in fetal central nervous system after ethylnitrosourea administration.
Topics: Alkylating Agents; Animals; Apoptosis; Cell Cycle; Down-Regulation; Ethylnitrosourea; Female; Fetus; Gene Expression; Oligonucleotide Array Sequence Analysis; Pregnancy; Prenatal Injuries; Rats; Telencephalon; Up-Regulation | 2005 |
Lung tumor location and lymphocyte infiltration in mice are genetically determined.
Topics: Alkylating Agents; Animals; Bronchi; Drug Administration Schedule; Ethylnitrosourea; Female; Injections, Intraperitoneal; Lung; Lung Neoplasms; Lymphocytes; Mice; Mice, Inbred Strains; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Species Specificity | 2005 |
Neurogenic tumors in rats induced by ethylnitrosourea.
Topics: Alkylating Agents; Animals; Carcinogens; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Injections, Intravenous; Maternal Exposure; Neoplasms, Radiation-Induced; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Radio Waves; Rats; Rats, Sprague-Dawley | 2005 |
l7Rn6 encodes a novel protein required for clara cell function in mouse lung development.
Topics: Amino Acid Sequence; Animals; Base Sequence; Bronchi; Cell Differentiation; Cloning, Molecular; Cytoplasm; Endoplasmic Reticulum; Enzyme Inhibitors; Epithelial Cells; Ethylnitrosourea; Female; Gene Expression Regulation, Developmental; Gestational Age; Golgi Apparatus; Lung; Mice; Mice, Transgenic; Molecular Sequence Data; Phospholipases A; Pregnancy; Proteins; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein B; Rabbits; Sequence Homology, Amino Acid; Uteroglobin | 2006 |
Cardiovascular phenotyping of fetal mice by noninvasive high-frequency ultrasound facilitates recovery of ENU-induced mutations causing congenital cardiac and extracardiac defects.
Topics: Abnormalities, Multiple; Animals; Cardiovascular Physiological Phenomena; Ethylnitrosourea; Female; Fetus; Heart Defects, Congenital; Mice; Mutation; Pregnancy; Ultrasonography, Prenatal | 2005 |
Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors.
Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Count; Cell Division; Cell Transformation, Neoplastic; Cerebral Ventricles; DNA Damage; Ethylnitrosourea; Female; Gene Expression Regulation; Genes, p53; Genetic Vectors; Glioblastoma; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multipotent Stem Cells; Neoplasms, Radiation-Induced; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Time Factors; Tumor Suppressor Protein p53 | 2006 |
Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Astrocytes; Biomarkers, Tumor; Cerebral Cortex; Disease Models, Animal; Disease Progression; Ethylnitrosourea; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Immunohistochemistry; Intermediate Filament Proteins; Nerve Tissue Proteins; Nestin; Osteopontin; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Time Factors; Transfection | 2006 |
pERK, pAkt and pBad: a possible role in cell proliferation and sustained cellular survival during tumorigenesis and tumor progression in ENU induced transplacental glioma rat model.
Topics: Alkylating Agents; Animals; bcl-Associated Death Protein; Brain; Cell Proliferation; Cell Survival; Disease Models, Animal; Enzyme Activation; Ethylnitrosourea; Extracellular Signal-Regulated MAP Kinases; Female; Glioma; Male; Phosphorylation; Placenta; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction | 2006 |
A series of ENU-induced single-base substitutions in a long-range cis-element altering Sonic hedgehog expression in the developing mouse limb bud.
Topics: Animals; Base Sequence; Conserved Sequence; DNA Primers; Enhancer Elements, Genetic; Ethylnitrosourea; Extremities; Female; Gene Expression Regulation, Developmental; Genes, Regulator; Genes, Reporter; Genetic Complementation Test; Hedgehog Proteins; In Situ Hybridization; Limb Deformities, Congenital; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Mutant Strains; Mice, Transgenic; Phenotype; Point Mutation; Polymorphism, Single Nucleotide; Pregnancy | 2007 |
HGPRT mutation induction by N-ethyl-N-nitrosourea as measured by 6-thioguanine resistance is higher in male than in female Syrian hamster fetuses.
Topics: Animals; Cells, Cultured; Cricetinae; Ethylnitrosourea; Female; Fetus; Hypoxanthine Phosphoribosyltransferase; Male; Mesocricetus; Mutagenesis; Pregnancy; Sex Characteristics; Thioguanine | 2006 |
ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit.
Topics: Adipose Tissue; Animals; Base Sequence; Blotting, Western; Carnitine; Chromosome Mapping; Ethylnitrosourea; Fatty Liver; Female; Fibrosis; Lipid Metabolism Disorders; Male; Mice; Mice, Inbred C57BL; Mitochondrial Trifunctional Protein; Mitochondrial Trifunctional Protein, alpha Subunit; Mitochondrial Trifunctional Protein, beta Subunit; Multienzyme Complexes; Mutagenesis; Myocardium; Point Mutation; Polymerase Chain Reaction; Pregnancy; Tandem Mass Spectrometry | 2006 |
VEGF immunopositivity related to malignancy degree, proliferative activity and angiogenesis in ENU-induced gliomas.
Topics: Alkylating Agents; Animals; Cell Proliferation; Ethylnitrosourea; Female; Fetus; Glioma; Humans; Neoplasm Staging; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2007 |
N-ethyl-N-nitrosourea (ENU)-induced meningiomatosis and meningioma in p16(INK4a)/p19(ARF) tumor suppressor gene-deficient mice.
Topics: Animals; Cyclin-Dependent Kinase Inhibitor p16; Ethylnitrosourea; Female; Fetus; Genes, p16; Genes, Tumor Suppressor; Male; Meningeal Neoplasms; Meningioma; Mice; Mice, Inbred C57BL; Pregnancy | 2007 |
Dietary prevention of malignant glioma aggressiveness, implications in oxidant stress and apoptosis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Ethylnitrosourea; Female; Fruit; Glioma; Immunohistochemistry; Male; Mitochondria, Liver; Oxidative Stress; Polymerase Chain Reaction; Pregnancy; Rats; RNA, Neoplasm; Vegetables | 2008 |
Electron-microscopic analysis of nephroblastomas induced transplacentally in the IIIVO/J rabbit by a single dose of N-ethylnitrosourea.
Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Models, Animal; Ethylnitrosourea; Female; Kidney Glomerulus; Kidney Neoplasms; Kidney Tubules; Mesenchymoma; Nitrosourea Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Wilms Tumor | 1984 |
Transplacental and direct exposure of mouse and marmoset to ethylnitrosourea: analysis of chromosome aberrations.
Topics: Animals; Bone Marrow Cells; Callitrichinae; Chromosome Aberrations; Chromosomes; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mice; Nitrosourea Compounds; Pregnancy; Species Specificity | 1983 |
Nucleic acids and protein in brains and cerebella of rats transplacentally exposed to ethylnitrosourea.
Topics: Animals; Brain; Cerebellum; DNA; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Nerve Tissue Proteins; Nitrosourea Compounds; Pregnancy; Rats; RNA | 1981 |
[Experimental models of embryonic nephroblastomas (Wilms' tumor)].
Topics: Animals; Dimethylnitrosamine; Disease Models, Animal; Enzyme Activation; Ethylnitrosourea; Female; Kidney Neoplasms; Neoplasms, Experimental; Pregnancy; Rats; Time Factors; Wilms Tumor | 1980 |
Transplacental teratogenic and carcinogenic effects in rabbits chronically treated with N-ethyl-N-nitrosourea.
Topics: Animals; Carcinogens; Ethylnitrosourea; Female; Jaw Neoplasms; Kidney Neoplasms; Limb Deformities, Congenital; Maternal-Fetal Exchange; Neurofibroma; Nitrosourea Compounds; Osteosarcoma; Parietal Bone; Pregnancy; Rabbits; Rats; Spinal Cord Neoplasms; Teratogens; Wilms Tumor | 1980 |
Histological and ultrastructural studies of nephroblastoma in rats induced transplacentally by ethylnitrosourea.
Topics: Animals; Connective Tissue; Epithelial Cells; Ethylnitrosourea; Female; Kidney; Kidney Neoplasms; Male; Mesoderm; Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains; Wilms Tumor | 1982 |
Histologic characterization of renal tumors (nephroblastomas) induced transplacentally in IIIVO/J and WH/J rabbits by N-ethylnitrosourea.
Topics: Abdominal Neoplasms; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelium; Ethylnitrosourea; Female; Humans; Kidney Glomerulus; Kidney Neoplasms; Kidney Tubules; Lung Neoplasms; Maternal-Fetal Exchange; Neoplasms, Connective Tissue; Pregnancy; Rabbits; Wilms Tumor | 1983 |
Intranuclear inclusions in mouse neurons.
Topics: Animals; Brain; Ethylnitrosourea; Female; Inclusion Bodies; Mice; Neurons; Pregnancy | 1984 |
Experimental cancer prophylaxis.
Topics: Adenoma; Animals; Diterpenes; Ethylnitrosourea; Female; Fetus; Leukemia, Experimental; Lung Neoplasms; Male; Methylcholanthrene; Mice; Peptide Hydrolases; Pregnancy; Retinyl Esters; Sarcoma, Experimental; Vitamin A; Water Supply | 1983 |
Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antipain; Caffeine; Carcinogens; Ethylnitrosourea; Female; Fetus; Hydroxamic Acids; Methylnitrosourea; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Oligopeptides; Pregnancy; Teratogens; Tretinoin; Urethane | 1983 |
Distribution pattern of DNA template activity in the developing cerebellar cortex in rats and its alteration after transplacental administration of ethylnitrosourea.
Topics: Acridine Orange; Animals; Cerebellar Cortex; DNA; Ethylnitrosourea; Female; Gestational Age; Histocytochemistry; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Templates, Genetic | 1984 |
[Effect of phenformin and succinic acid on the transplacental carcinogenic effect of N-nitroso-N-ethylurea in rats].
Topics: Animals; Ethylnitrosourea; Female; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Phenformin; Pregnancy; Rats; Succinates; Succinic Acid | 1984 |
[Effect of selenium on transplacental carcinogenesis].
Topics: Animals; Drug Antagonism; Ethylnitrosourea; Female; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Selenium; Urethane | 1984 |
[DNA levels in the cell nuclei of nervous system tumors induced by ethylnitrosourea].
Topics: Animals; DNA, Neoplasm; Ethylnitrosourea; Female; Glioma; Nervous System Neoplasms; Ploidies; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Trigeminal Nuclei | 1984 |
Stem cell carcinoma in the small intestine of mice treated transplacentally with N-ethyl-N-nitrosourea: some quantitative and histological aspects.
Topics: Adenocarcinoma; Animals; Epithelium; Ethylnitrosourea; Female; Intestinal Neoplasms; Intestine, Small; Male; Mice; Mice, Inbred Strains; Neoplastic Stem Cells; Placenta; Pregnancy; Stem Cells; Time Factors | 1984 |
[Effect of polypeptide factors of the thymus, pineal gland, bone marrow and anterior hypothalamus on the realization of transplacental carcinogenesis].
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Kidney Neoplasms; Male; Neoplasms, Experimental; Peptides; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spinal Cord Neoplasms; Thymus Hormones | 1984 |
Spinal cord tumors induced by N-ethyl-N-nitrosourea in rats: presence of spinal subpial target cells.
Topics: Aging; Animals; Animals, Newborn; Brain; DNA Replication; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Nitrosourea Compounds; Organ Size; Pregnancy; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity; Spinal Cord; Spinal Cord Neoplasms | 1984 |
[Carcinogenesis in rats under the combined transplacental action of sex hormones and nitrosoethylurea].
Topics: Adrenal Gland Neoplasms; Animals; Dienestrol; Drug Synergism; Ethylnitrosourea; Female; Fetus; Gonadal Steroid Hormones; Leydig Cell Tumor; Male; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Ovarian Neoplasms; Pregnancy; Rats; Sarcoma, Experimental; Testicular Neoplasms; Testosterone; Thyroid Neoplasms; Uterine Neoplasms | 1983 |
Permanent alterations in the rat spinal cord following prenatal exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Dendrites; Ethylnitrosourea; Female; Gestational Age; Maternal-Fetal Exchange; Neurons; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord; Substantia Gelatinosa | 1983 |
Tissue culture of trigeminal nerves from rats administered transplacentally with ethylnitrosourea.
Topics: Aging; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Microscopy, Electron; Neoplasm Transplantation; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Trigeminal Nerve | 1983 |
Regional blood flow in ethylnitrosourea-induced brain tumors.
Topics: Animals; Astrocytoma; Blood Flow Velocity; Brain Neoplasms; Cerebrovascular Circulation; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains; Regional Blood Flow | 1983 |
Regional blood-to-tissue transport in ethylnitrosourea-induced brain tumors.
Topics: Aminoisobutyric Acids; Animals; Astrocytoma; Blood-Brain Barrier; Brain; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Ethylnitrosourea; Female; Glioma; Kinetics; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Teratogenic effect of extended administration of N-nitrosoethylurea and ethylurea/nitrite in rats.
Topics: Animals; Ethylnitrosourea; Female; Nitrites; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Teratogens; Urea | 1983 |
DNA repair following ultraviolet and N-ethyl-N-nitrosourea treatment of cells cultured from human fetal brain, intestine, kidney, liver, and skin.
Topics: Brain; Cells, Cultured; DNA Repair; DNA Replication; Ethylnitrosourea; Female; Fetus; Humans; Intestinal Mucosa; Kidney; Liver; Nitrosourea Compounds; Organ Specificity; Pregnancy; Skin; Ultraviolet Rays | 1983 |
Plexiform structures in malignant schwannomas after prenatal exposure to ethylnitrosourea.
Topics: Animals; Ethylnitrosourea; Female; Male; Mitosis; Neurilemmoma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1983 |
Prevention of transplacentally induced malignant diseases.
Topics: Animals; Ethylnitrosourea; Female; Leukemia, Experimental; Male; Mice; Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Vitamin A | 1984 |
Effects of carbamoylation on cell survival and DNA repair in normal human embryo cells (IMR-90) treated with various 1-(2-chloroethyl)-1-nitrosoureas.
Topics: Carmustine; Cell Line; Cell Survival; DNA; DNA Repair; DNA Replication; Ethylnitrosourea; Female; Humans; Lomustine; Lung; Nitrosourea Compounds; Pregnancy; Structure-Activity Relationship | 1984 |
The mammalian spot test and its use for testing of mutagenic and carcinogenic potential: experience with the pesticide chlordimeform, its principal metabolites and the drug lisuride hydrogen maleate.
Topics: Amidines; Animals; Biotransformation; Carcinogens; Chlorphenamidine; Drug Evaluation, Preclinical; Ergolines; Ethylnitrosourea; Female; Genes, Dominant; Genes, Lethal; Genotype; Lisuride; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutagens; Mutation; Pregnancy | 1984 |
The effect of nerve growth factor and antibodies to nerve growth factor on ethylnitrosourea-induced neoplastic proliferation in rat trigeminal nerves.
Topics: Animals; Antibodies; Cell Transformation, Neoplastic; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Male; Mice; Nerve Growth Factors; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Trigeminal Nerve | 1984 |
[Effect of tumor promoting agents on the in vitro malignant transformation of the fetal rat brain cells exposed in utero to ethylnitrosourea].
Topics: Animals; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Fetus; In Vitro Techniques; Maternal-Fetal Exchange; Nitrosourea Compounds; Phenobarbital; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1984 |
[Initial cellular damage in the developing rat brain caused by cytotoxicity of ethylnitrosourea].
Topics: Animals; Brain; Brain Diseases; Cell Cycle; Cell Differentiation; Ethylnitrosourea; Female; Fetal Diseases; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats | 1984 |
Lack of promotion effect of phenobarbital on pulmonary tumorigenesis in ddy mice initiated by transplacental exposure to 1-ethyl-1-nitrosourea.
Topics: Animals; Ethylnitrosourea; Female; Lung; Lung Neoplasms; Male; Mice; Nitrosourea Compounds; Phenobarbital; Placenta; Pregnancy; Prenatal Exposure Delayed Effects | 1984 |
[Mechanisms of the tumor promoting effect of 12-0-tetradecanoyl phorbol 13-acetate on the ethylnitrosourea induced transplacental neurogenic carcinogenesis].
Topics: Animals; Brain Neoplasms; Carcinogens; Chromosome Aberrations; DNA, Neoplasm; Ethylnitrosourea; Female; Gene Expression Regulation; In Vitro Techniques; Maternal-Fetal Exchange; Neoplasm Proteins; Phorbols; Pregnancy; Rats; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymidine | 1984 |
[Enzymohistochemical study of the tumors from the transplacental and postnatal exposure to various carcinogens].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Carcinogens; Enzyme Activation; Ethylnitrosourea; Female; Gestational Age; Histocytochemistry; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1980 |
Timing of chemically induced neoplasia in mice revealed by the antineoplastic action of caffeine.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; DNA Repair; Ethylnitrosourea; Female; Hydroxamic Acids; Lung Neoplasms; Maternal-Fetal Exchange; Methylnitrosourea; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Nitroquinolines; Pregnancy; Time Factors; Urethane | 1980 |
Multiple genes in the H-2 complex affect differently the number and growth rate of transplacentally induced lung tumours in mice.
Topics: Animals; Ethylnitrosourea; Female; H-2 Antigens; Lung Neoplasms; Major Histocompatibility Complex; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Pregnancy | 1983 |
Mutagenicity studies with the mouse spot test.
Topics: 2-Acetylaminofluorene; Animals; Colchicine; Embryo, Mammalian; Environmental Pollution; Ethyl Methanesulfonate; Ethylene Dichlorides; Ethylnitrosourea; Female; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutagens; Mutation; Pregnancy | 1983 |
Structural modifications and repair of DNA in neuro-oncogenesis by N-ethyl-N-nitrosourea.
Topics: Aging; Alkylation; Animals; Cell Differentiation; DNA; DNA Repair; Ethylnitrosourea; Female; Fetus; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Pregnancy; Rats | 1983 |
Elimination of O6-ethylguanine from the DNA of brain, liver, and other rat tissues exposed to ethylnitrosourea at different stages of prenatal development.
Topics: Animals; Brain; DNA; Ethylnitrosourea; Female; Fetus; Guanine; Kinetics; Liver; Male; Nitrosourea Compounds; Pregnancy; Rats | 1983 |
Influence of vitamin A on the formation of ethylnitrosourea (ENU)-induced leukemias.
Topics: Adenoma; Aging; Animals; Diterpenes; Ethylnitrosourea; Female; Leukemia, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Retinyl Esters; Vitamin A | 1983 |
Pretreatment of normal human fibroblasts and human colon carcinoma cells with MNNG allows chloroethylnitrosourea to produce DNA interstrand crosslinks not observed in cells treated with chloroethylnitrosourea alone.
Topics: Cell Line; Cell Survival; Colonic Neoplasms; DNA; Ethylnitrosourea; Female; Fibroblasts; Humans; Methylnitronitrosoguanidine; Nitrosourea Compounds; Pregnancy; Time Factors | 1983 |
Initiation of focal hyperplastic hepatic lesions by transplacental administration of ethylnitrosourea in rats of F1 generation, and no transmission of the effect to F2 and F3 generations.
Topics: 2-Acetylaminofluorene; Animals; Ethylnitrosourea; Female; Hepatectomy; Hyperplasia; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Rats; Rats, Inbred F344 | 1983 |
Transformation of oligodendroglia: a para- or preneoplastic effect of ethylnitrosourea on mouse brain.
Topics: Animals; Cell Transformation, Neoplastic; Demyelinating Diseases; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mice; Microscopy, Electron; Neuroglia; Nitrosourea Compounds; Oligodendroglia; Pregnancy | 1983 |
Early stage of development of transplacentally induced glioma with ethylnitrosourea in rats. Sequential historadioautographic and electron microscopic studies.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Division; Ethylnitrosourea; Female; Fetal Diseases; Glioma; Microscopy, Electron; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
In vitro transformation of fetal brain cells from CDF rats exposed in utero to N-ethyl-N-nitrosourea: morphologic and immunologic studies.
Topics: Animals; Animals, Newborn; Antibody Formation; Brain; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Thymectomy; Transplantation, Isogeneic | 1980 |
Glycosaminoglycans of brain tumors transplacentally induced by ENU in the rat.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Glycosaminoglycans; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglia; Oligodendroglioma; Pregnancy; Rats | 1981 |
Electrophoretically detected germinal mutations induced in the mouse by ethylnitrosourea.
Topics: Alleles; Animals; Electrophoresis, Starch Gel; Ethylnitrosourea; Female; Genes, Dominant; Genes, Lethal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutation; Nitrosourea Compounds; Pregnancy; Proteins; Species Specificity; Spermatogonia; Spermatozoa | 1981 |
Genetics of transplacentally induced teratogenic and carcinogenic effects in rabbits treated with N-nitroso-N-ethylurea.
Topics: Animals; Ethylnitrosourea; Female; Kidney Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Neurofibroma; Nitrosourea Compounds; Pregnancy; Rabbits; Sex Factors; Species Specificity | 1982 |
Pathology of gestational choriocarcinoma induced in patas monkeys by ethylnitrosourea given during pregnancy.
Topics: Animals; Choriocarcinoma; Erythrocebus patas; Ethylnitrosourea; Female; Pregnancy; Pregnancy Complications, Neoplastic; Uterine Neoplasms | 1981 |
Reduction of ethylnitrosourea-induced neoplastic proliferation in rat trigeminal nerves by nerve growth factor.
Topics: Age Factors; Animals; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Gestational Age; Maternal-Fetal Exchange; Neoplasms, Experimental; Nerve Growth Factors; Neurilemmoma; Nitrosourea Compounds; Precancerous Conditions; Pregnancy; Rats; Trigeminal Nerve | 1982 |
Ultrastructural findings in so-called ependymal rat tumors induced by transplacental administration of ethylnitrosourea (ENU).
Topics: Animals; Brain Neoplasms; Cilia; Ependymoma; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Microscopy, Electron; Microtubules; Microvilli; Polyribosomes; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
DNA template activity in rat brain tumors induced by transplacental administration of ethylnitrosourea.
Topics: Acridine Orange; Animals; Brain Neoplasms; DNA, Neoplasm; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Oligodendroglioma; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Templates, Genetic | 1982 |
Experimental chemotherapy with N'N'-bis(2-chloroethyl)-N-nitrosourea (BCNU) in autochthonous neurogenic tumors of the rat transplacentally induced by ethylnitrosourea.
Topics: Animals; Carmustine; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Neoplasms, Experimental; Nervous System Neoplasms; Pregnancy; Rats | 1982 |
Sensitivity to carcinogenesis in nude mice: skin tumors caused by transplacental exposure to ethylnitrosourea.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mice; Mice, Nude; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Sebaceous Gland Neoplasms; Skin Neoplasms | 1982 |
Congenital malformations of the central nervous system and transplacental carcinogenesis: modification of ethylnitrosourea-induced brain tumors in rats by pretreatment with methylazoxymethanol.
Topics: Animals; Azo Compounds; Brain Neoplasms; Ethylnitrosourea; Female; Methylazoxymethanol Acetate; Microcephaly; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Chemical and viral agents in prenatal experimental carcinogenesis.
Topics: Adolescent; Animals; Child; Child, Preschool; Ethylnitrosourea; Female; Humans; Infant; Infant, Newborn; Neoplasms; Neoplasms, Experimental; Nervous System Neoplasms; Pregnancy; Rats | 1982 |
Dose-related reduction by prenatal x-irradiation of the transplacental neurocarcinogenicity of ethylnitrosourea in rats.
Topics: Animals; Dose-Response Relationship, Radiation; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Pregnancy; Pregnancy, Animal; Rats; Time Factors; X-Rays | 1980 |
Retention of promutagenic O6-ethylguanine in the DNA of various rat tissues following transplacental inoculation with ethylnitrosourea.
Topics: Alkylation; Animals; Brain; DNA; DNA Replication; Ethylnitrosourea; Female; Guanine; Kidney; Liver; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1980 |
Histogenesis of the papillary Clara cell adenoma.
Topics: Age Factors; Animals; Cystadenoma; Ethylnitrosourea; Female; Lung Neoplasms; Mice; Neoplasms, Experimental; Pregnancy | 1981 |
The fatty acid pattern of central myelin lipids after transplacental intoxication by ethylnitrosourea.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Central Nervous System; Ethylnitrosourea; Fatty Acids; Female; Lipid Metabolism; Maternal-Fetal Exchange; Metabolism, Inborn Errors; Mice; Myelin Sheath; Nitrosourea Compounds; Pregnancy | 1981 |
Transplacental and postnatal ethylnitrosourea-induced leukemia and neurogenic tumors in Donryu rats.
Topics: Animals; Chromosome Aberrations; Ethylnitrosourea; Female; Leukemia, Experimental; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Pregnancy; Rats | 1981 |
Transplacental carcinogenic effect of n-nitrosoethylurea in dogs.
Topics: Animals; Brain Neoplasms; Dogs; Ethylnitrosourea; Female; Fetus; Kidney Neoplasms; Male; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Splenic Neoplasms; Thyroid Neoplasms | 1981 |
Cell culture systems to study glial transformation.
Topics: Animals; Astrocytes; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Ethylnitrosourea; Female; Glioma; Humans; Maternal-Fetal Exchange; Neoplasms, Experimental; Neuroglia; Nitrosourea Compounds; Oligodendroglia; Pregnancy; Rats | 1980 |
Effect of age at treatment on the incidence and location of neurogenic tumors induced in Wistar rats by a single dose of N-ethyl-N-nitrosourea.
Topics: Age Factors; Animals; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Male; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sex Factors; Spinal Cord Neoplasms; Trigeminal Nerve | 1981 |
Increased cancer incidence in the progeny of male rats exposed to ethylnitrosourea before mating.
Topics: Animals; Ethylnitrosourea; Female; Male; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Spermatozoa; Time Factors | 1981 |
Responsiveness of fetal rat brain cells to glia maturation factor during neoplastic transformation in cell culture.
Topics: Animals; Brain; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Glia Maturation Factor; Microscopy, Electron, Scanning; Nerve Tissue Proteins; Neuroglia; Pregnancy; Rats; Swine | 1981 |
[Mammary tumors in female rats with combined exposure to nitrosoethylurea and sex hormones].
Topics: Adenofibroma; Animals; Drug Interactions; Ethylnitrosourea; Female; Gonadal Steroid Hormones; Mammary Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Rats; Testosterone | 1981 |
Prenatal susceptibility to carcinogenesis by xenobiotic substances including vinyl chloride.
Topics: Animals; Biotransformation; Cercopithecidae; Ethylene Oxide; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Pregnancy; Rats; Rats, Inbred Strains; Vinyl Chloride; Vinyl Compounds | 1981 |
Experimental brain tumors by transplacental ENU. Multifactorial study of the latency period.
Topics: Adenylyl Cyclases; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Hyperplasia; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Time Factors | 1980 |
Influence of chronic Toxoplasma infection on ethylnitrosourea-induced central nervous system tumors in rats.
Topics: Animals; Astrocytoma; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Immunity; Inflammation; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Toxoplasmosis, Animal | 1980 |
A scanning electron microscopic study of the Type II and Clara cell adenoma of the mouse lung.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Lung Neoplasms; Mice; Microscopy, Electron, Scanning; Neoplasms, Experimental; Pregnancy | 1980 |
Role of nerve growth factor in ethylnitrosourea-induced neural carcinogenesis.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Hydroxydopamines; Neoplasms, Experimental; Nerve Growth Factors; Nitrosourea Compounds; Pregnancy; Rats | 1980 |
Effect of stage of development on frequency and pathogenesis of kidney tumors induced in Noble (Nb) rats exposed prenatally or neonatally to N-nitrosoethylurea.
Topics: Animals; Animals, Newborn; Carcinogens; Ethylnitrosourea; Female; Kidney Neoplasms; Male; Maternal-Fetal Exchange; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Wilms Tumor | 1995 |
Polyamine acetylation in rat brain during N-ethyl-N-nitrosourea-induced cerebral carcinogenesis.
Topics: Acetyltransferases; Animals; Brain; Carcinogens; Ethylnitrosourea; Female; Gestational Age; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Polyamines; Pregnancy; Rats; Time Factors | 1995 |
Inhibitory effects of coffee on transplacental genotoxicity in mice.
Topics: Analysis of Variance; Animals; Antimutagenic Agents; Bone Marrow; Bone Marrow Cells; Coffee; Cyclophosphamide; Diethylnitrosamine; Erythrocytes; Ethylnitrosourea; Female; Fetal Blood; Liver; Maternal-Fetal Exchange; Mice; Micronucleus Tests; Mitomycin; Poisson Distribution; Pregnancy | 1995 |
Modulation of nitrosourea toxicity in rodent embryonic cells by O6-benzylguanine, a depletor of O6-methylguanine-DNA methyltransferase.
Topics: Animals; Cell Differentiation; Cells, Cultured; DNA Adducts; Ethylnitrosourea; Female; Guanine; Mesencephalon; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Pregnancy; Rats; Rats, Sprague-Dawley | 1995 |
Consideration of the liver of embryonic lacZ transgenic mice as an analogue of the mouse coat colour spot test: preliminary data and technical problems.
Topics: Animals; DNA Mutational Analysis; Ethylnitrosourea; Female; Lac Operon; Liver; Mice; Mice, Transgenic; Mutagenicity Tests; Mutation; Pregnancy | 1995 |
A gene for susceptibility to small intestinal cancer, ssic1, maps to the distal part of mouse chromosome 4.
Topics: Animals; Chromosome Mapping; Ethylnitrosourea; Female; Genotype; Haplotypes; Intestinal Neoplasms; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pregnancy; Prenatal Exposure Delayed Effects | 1995 |
The induction of recessive mutations in mouse primordial germ cells with N-ethyl-N-nitrosourea.
Topics: Age Factors; Animals; Ethylnitrosourea; Female; Fertility; Genes, Recessive; Germ Cells; Germ-Line Mutation; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Mutagens; Pregnancy; Spermatogonia | 1993 |
Congenital malformations in the offspring of male mice treated with ethylnitrosourea at the embryonic stage.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Embryonic and Fetal Development; Ethylnitrosourea; Female; Male; Mice; Mice, Inbred ICR; Pregnancy; Prenatal Exposure Delayed Effects | 1994 |
The Japanese medaka, Oryzias latipes, as a new model organism for studying environmental germ-cell mutagenesis.
Topics: Animals; Disease Models, Animal; Environmental Pollutants; Ethylnitrosourea; Female; Gamma Rays; Germ-Line Mutation; Male; Mutagenesis; Mutagens; Oryzias; Pregnancy; Spermatogenesis | 1994 |
Experimental induction of primitive neuro-ectodermal tumours in rats: a re-appraisement of the ENU-model of neurocarcinogenesis.
Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Immunoenzyme Techniques; Male; Microscopy, Electron; Neoplasm Transplantation; Neuroectodermal Tumors, Primitive; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 1994 |
Influence of the postnatal administration of tumor necrosis factor plus interferon-alpha 2b on the development of ethyl-nitrosourea-induced brain tumors in rats.
Topics: Aging; Animals; Brain Neoplasms; Ethylnitrosourea; Female; Interferon alpha-2; Interferon-alpha; Neurilemmoma; Oligodendroglioma; Pregnancy; Rats; Rats, Wistar; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Anitumoral effect of thallium against N-ethyl-N-nitroso-urea-induced brain tumors.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Ethylnitrosourea; Female; Injections; Placenta; Pregnancy; Rats; Rats, Wistar; Thallium | 1994 |
Gangliosides modulate the development of ethyl-nitrosourea induced brain tumors in rats.
Topics: Animals; Brain Neoplasms; Cattle; Ethylnitrosourea; Female; Gangliosides; Immunologic Factors; Pregnancy; Rats; Rats, Wistar | 1994 |
Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas.
Topics: Acetylation; Acetyltransferases; Animals; Brain; Brain Neoplasms; Catalysis; Cytosol; Ethylnitrosourea; Female; Glioma; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spermidine | 1994 |
Genetic predisposition to transplacentally induced renal cell carcinomas in the Eker rat.
Topics: Animals; Carcinoma, Renal Cell; Ethylnitrosourea; Female; Fetus; Kidney Neoplasms; Male; Mutation; Oncogenes; Pregnancy; Rats; Rats, Mutant Strains; Wilms Tumor | 1993 |
Deletion mapping of four loci defined by N-ethyl-N-nitrosourea-induced postimplantation-lethal mutations within the pid-Hbb region of mouse chromosome 7.
Topics: Animals; Chromosome Mapping; Embryonic Development; Ethylnitrosourea; Female; Fetal Death; Genes, Lethal; Homozygote; Male; Mice; Mutation; Pregnancy; Sequence Deletion | 1993 |
Infiltrating angiolipoma of skeletal muscle. Transplacental induction in nonhuman primates by N-nitrosoethylurea.
Topics: Animals; Erythrocebus patas; Ethylnitrosourea; Female; Hemangioma; Immunohistochemistry; Lipoma; Macaca mulatta; Male; Microscopy, Electron; Microscopy, Immunoelectron; Muscular Diseases; Pregnancy; Prenatal Exposure Delayed Effects | 1993 |
Complementary tumor induction in neural grafts exposed to N-ethyl-N-nitrosourea and an activated myc gene.
Topics: Animals; Base Sequence; Brain; Brain Neoplasms; Brain Tissue Transplantation; Cell Transformation, Neoplastic; Cocarcinogenesis; Ethylnitrosourea; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Male; Maternal-Fetal Exchange; Molecular Sequence Data; Pregnancy; Rats; Rats, Inbred F344; Transfection | 1993 |
N-ethyl-N-nitrosourea-induced prenatally lethal mutations define at least two complementation groups within the embryonic ectoderm development (eed) locus in mouse chromosome 7.
Topics: Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Ectoderm; Embryonic and Fetal Development; Ethylnitrosourea; Female; Gene Deletion; Genes, Lethal; Genetic Complementation Test; Male; Mice; Mutagenesis; Phenotype; Pregnancy | 1993 |
Diamine oxidase activity in rat brain carcinogenesis and in gliomas.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain Neoplasms; Ethylnitrosourea; Female; Fetus; Glioma; Male; Precancerous Conditions; Pregnancy; Prenatal Exposure Delayed Effects; Putrescine; Rats | 1993 |
Study of the post-natal effects of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. II. Influence of low-molecular-weight polypeptide factors from the thymus, pineal gland, bone marrow, anterior hypothalamus, brain
Topics: Animals; Anticarcinogenic Agents; Bone Marrow; Brain; Brain Neoplasms; Carcinogens; Central Nervous System Neoplasms; Cerebral Cortex; Ethylnitrosourea; Female; Hypothalamus, Anterior; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms, Experimental; Peptides; Peripheral Nervous System Neoplasms; Pineal Gland; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms; Thymus Gland; Tissue Extracts | 1996 |
Study of post-natal effect of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. III. Inhibitory action of indomethacin, voltaren, theophylline and epsilon-aminocaproic acid.
Topics: Aminocaproic Acid; Animals; Anticarcinogenic Agents; Brain Neoplasms; Carcinogens; Central Nervous System Neoplasms; Diclofenac; Ethylnitrosourea; Female; Indomethacin; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms, Experimental; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spinal Cord Neoplasms; Theophylline | 1996 |
Age- and dose-dependent transplacental carcinogenesis by N-nitrosoethylurea in Syrian golden hamsters.
Topics: Age Factors; Animals; Carcinogens; Cricetinae; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Mesocricetus; Neoplasms, Experimental; Nervous System Neoplasms; Peripheral Nervous System; Pregnancy | 1996 |
Testicular development and fertility of mice treated prenatally with N-nitroso-N-ethylurea at various gestational stages.
Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Body Weight; Ethylnitrosourea; Female; Fertility; Gestational Age; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Organ Size; Pregnancy; Teratogens; Testis | 1996 |
Loss of p53 is an early event in induction of brain tumors in mice by transplacental carcinogen exposure.
Topics: Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Fetus; Gene Deletion; Genes, p53; Humans; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pregnancy | 1997 |
The activity of ENU, iPMS and MMS in male mouse germ cells using the Muta Mouse positive selection transgenic mutation assay.
Topics: Animals; DNA; Epididymis; Ethylnitrosourea; Female; Male; Mesylates; Methyl Methanesulfonate; Mice; Mice, Inbred CBA; Mice, Transgenic; Mutagenicity Tests; Mutagens; Oligospermia; Ovum; Pregnancy; Sperm Count; Spermatozoa; Testis | 1997 |
Effects of basic fibroblast growth factor on in vivo cerebral tumorigenesis in rats.
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Fibroblast Growth Factor 2; Glioma; Humans; Male; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1997 |
Male-mediated teratogenesis: spectrum of congenital malformations in the offspring of A/J male mice treated with ethylnitrosourea.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Cleft Palate; Ethylnitrosourea; Fathers; Female; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Paternal Exposure; Pregnancy; Teratogens; Testis | 1996 |
Drug resistance and apoptosis in ENU-induced rat brain tumors treated with anti-cancer drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; DNA Nucleotidylexotransferase; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Nimustine; Pregnancy; Rats; Rats, Wistar; Vincristine | 1998 |
Glial tumoral proliferation induces changes in the state and physical properties of water during ENU-induction of brain tumors in rats.
Topics: Animals; Cell Division; Ethylnitrosourea; Female; Glioma; Magnetic Resonance Spectroscopy; Maternal-Fetal Exchange; Pregnancy; Rats; Temperature; Water | 1998 |
Process of repair in the neuroepithelium of developing rat brain during neurogenesis: chronological and quantitative observation of DNA-replicating cells.
Topics: Alkylating Agents; Animals; Antimetabolites; Bromodeoxyuridine; Cell Count; Cell Division; Cytotoxins; DNA Replication; Ethylnitrosourea; Female; Male; Mitosis; Neocortex; Nerve Regeneration; Neurons; Neuropil; Pregnancy; Rats; Rats, Wistar | 1998 |
Specific induction of hepatocellular adenomas by transplacental administration of ENU in the tsc2 gene mutant (Eker) rat.
Topics: Adenoma, Liver Cell; Animals; Carcinogens; Ethylnitrosourea; Female; Genes, Tumor Suppressor; Liver Neoplasms; Male; Maternal-Fetal Exchange; Mutation; Pregnancy; Rats; Rats, Long-Evans; Repressor Proteins; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 1998 |
Changes in VEGF expression and in the vasculature during the growth of early-stage ethylnitrosourea-induced malignant astrocytomas in rats.
Topics: Animals; Astrocytoma; Blood Vessels; Brain Neoplasms; Endothelial Growth Factors; Ethylnitrosourea; Female; Immunoenzyme Techniques; Lymphokines; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; von Willebrand Factor | 1998 |
Effect of dietary vitamin A or N-acetylcysteine on ethylnitrosourea-induced rat gliomas.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Free Radical Scavengers; Glioma; Neuroectodermal Tumors; Pregnancy; Rats; Rats, Sprague-Dawley; Survival Analysis; Vitamin A | 1998 |
Laminin receptor alpha6beta4 integrin is highly expressed in ENU-induced glioma in rat.
Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Blood Vessels; Brain Neoplasms; Cell Division; Dimerization; Ethylnitrosourea; Female; Glioma; Humans; Integrin alpha6beta4; Integrins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic | 1999 |
Cell sensitivity to transplacental mutagenesis by N-ethyl-N-nitrosourea is greatest during early gestation in the Syrian hamster.
Topics: Animals; Cell Division; Cells, Cultured; Cricetinae; Diphtheria Toxin; Ethylnitrosourea; Female; Gestational Age; Litter Size; Maternal-Fetal Exchange; Mesocricetus; Mutagenesis; Mutagenicity Tests; Mutagens; Mutation; Pregnancy; Thioguanine | 1999 |
Cell sensitivity to transplacental carcinogenesis by N-ethyl-N-nitrosourea is greatest in early post-implantation development.
Topics: Animals; Brain; Carcinogens; Cricetinae; Embryonic Development; Ethylnitrosourea; Female; Gestational Age; Maternal-Fetal Exchange; Mesocricetus; Mutagenesis; Neuroectodermal Tumors; Pregnancy; Rats; Rats, Inbred Strains; Risk | 1999 |
Distribution and activity of transglutaminase in rat brain carcinogenesis and in gliomas.
Topics: Animals; Animals, Newborn; Brain; Brain Neoplasms; Carcinogenicity Tests; Carcinogens; Cytosol; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Subcellular Fractions; Time Factors; Transglutaminases | 1999 |
Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats chronically exposed to 836 MHz modulated microwaves.
Topics: Animals; Brain Neoplasms; Carcinogens; Central Nervous System Neoplasms; Cocarcinogenesis; Disease Models, Animal; Ethylnitrosourea; Female; Incidence; Male; Microwaves; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Spinal Cord Neoplasms | 1999 |
Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties.
Topics: Animals; Brain; Brain Neoplasms; Carcinogens; Endothelium, Vascular; Ethylnitrosourea; Female; Intercellular Junctions; Microcirculation; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Retroviridae Infections; Sarcoma Viruses, Murine; Sarcoma, Experimental; Tumor Cells, Cultured; Tumor Virus Infections | 1999 |
Activation of neu by missense point mutation in the transmembrane domain in schwannomas induced in C3H/HeNCr mice by transplacental exposure to N-nitrosoethylurea.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; DNA Mutational Analysis; DNA, Neoplasm; Ethylnitrosourea; Female; Gene Expression Regulation; Maternal-Fetal Exchange; Membrane Proteins; Mice; Mice, Inbred C3H; Molecular Sequence Data; Neurilemmoma; Placenta; Point Mutation; Polymorphism, Restriction Fragment Length; Pregnancy; Protein Structure, Tertiary; Receptor, ErbB-2; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transfection; Tumor Cells, Cultured | 1999 |
Evaluation of the potential promoting effect of 60 Hz magnetic fields on N-ethyl-N-nitrosourea induced neurogenic tumors in female F344 rats.
Topics: Animals; Body Weight; Brain Neoplasms; Central Nervous System Neoplasms; Electromagnetic Fields; Ethylnitrosourea; Female; Glioma; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats exposed to frequency-modulated microwave fields.
Topics: Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Gestational Age; Male; Microwaves; Neoplasms, Radiation-Induced; Pregnancy; Prenatal Exposure Delayed Effects; Radio Waves; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Survival; Weaning | 2000 |
Ethylnitrosourea (ENU)-induced apoptosis in the rat fetal tissues.
Topics: Alkylating Agents; Animals; Apoptosis; Carcinogens; Digestive System; Ethylnitrosourea; Female; Fetus; Gonads; Liver; Male; Pregnancy; Rats; Rats, Inbred F344; Teratogens | 2000 |
Teratologic studies on rat perinates and offspring from dams treated with ethylnitrosourea (ENU).
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Apoptosis; Body Weight; Cerebral Cortex; Ethylnitrosourea; Female; Fetal Growth Retardation; Fetal Weight; Forelimb; Organ Size; Pregnancy; Rats; Rats, Inbred F344; Tail; Teratogens; Toxicity Tests | 2000 |
Effect of light/dark regimen on N-nitrosoethylurea-induced transplacental carcinogenesis in rats.
Topics: Alkylating Agents; Animals; Darkness; Dose-Response Relationship, Radiation; Ethylnitrosourea; Female; Kidney Neoplasms; Light; Male; Neoplasms, Experimental; Nervous System Neoplasms; Peripheral Nervous System; Photoperiod; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Survival Analysis; Survival Rate | 2001 |
Apoptotic cell death and cell proliferative activity in the rat fetal central nervous system from dams administered with ethylnitrosourea (ENU).
Topics: Animals; Antimetabolites; Apoptosis; Bromodeoxyuridine; Carcinogens; Cell Division; Central Nervous System; DNA Fragmentation; Ethylnitrosourea; Female; Fetus; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron; Mitosis; Pregnancy; Rats; Rats, Inbred F344; Teratogens | 2001 |
The effects of 860 MHz radiofrequency radiation on the induction or promotion of brain tumors and other neoplasms in rats.
Topics: Animals; Brain Neoplasms; Cell Phone; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glioma; Male; Neoplasms; Neoplasms, Radiation-Induced; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Radio Waves; Rats; Rats, Sprague-Dawley; Spinal Cord Neoplasms; Spinal Nerves | 2001 |
Identification of a new chemically induced allele (Lp(m1Jus)) at the loop-tail locus: morphology, histology, and genetic mapping.
Topics: Alkylating Agents; Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Ethylnitrosourea; Female; Genetic Complementation Test; Genotype; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Neural Tube Defects; Phenotype; Pregnancy | 2001 |
Transplacental mutagenicity of N-ethyl-N-nitrosourea at the hprt locus in T-lymphocytes of exposed B6C3F1 mice.
Topics: Animals; Cells, Cultured; Ethylnitrosourea; Female; Hypoxanthine Phosphoribosyltransferase; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mutagens; Pregnancy; T-Lymphocytes | 2001 |
Complexity of lung cancer modifiers: mapping of thirty genes and twenty-five interactions in half of the mouse genome.
Topics: Animals; Animals, Congenic; Carcinogens; Chromosome Mapping; Ethylnitrosourea; Female; Genes; Genetic Predisposition to Disease; Genome; Genotype; Immunity, Innate; Karyotyping; Lung Neoplasms; Mice; Mice, Inbred C57BL; Phenotype; Pregnancy | 2001 |
Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethyl-nitrosourea exposure.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3; Caspase 9; Caspases; Ethylnitrosourea; Female; Gene Targeting; Genes, p53; Glioma; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Mice, Knockout; Neurons; Placenta; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Stem Cells | 2001 |
Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis.
Topics: Animals; Base Sequence; Chromosome Mapping; DNA; DNA Mutational Analysis; Embryonic and Fetal Development; Ethylnitrosourea; Female; Genes, Recessive; Haplotypes; Male; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mutagenesis; Mutation; Phenotype; Pregnancy | 2002 |
The antimalarials quinacrine and chloroquine potentiate the transplacental carcinogenic effect of ethylnitrosourea on ependymal cells.
Topics: Animals; Antimalarials; Brain Neoplasms; Carcinogens; Chloroquine; Drug Synergism; Ependyma; Ependymoma; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Immunoenzyme Techniques; Male; Pregnancy; Prenatal Exposure Delayed Effects; Quinacrine; Rats; Rats, Wistar; Spinal Cord Neoplasms; Synaptophysin | 2001 |
A comparative study of cytotoxic effects of N-ethyl-N-nitrosourea, adriamycin, and mono-(2-ethylhexyl)phthalate on mouse primordial germ cells.
Topics: Animals; Cell Line; Diethylhexyl Phthalate; Doxorubicin; Ethylnitrosourea; Female; Germ Cells; In Situ Nick-End Labeling; Mice; Pregnancy; Teratogens | 2002 |
Decreased glucocorticoid induction of brain glycerol phosphate dehydrogenase following transplacental carcinogenesis with ethylnitrosourea.
Topics: Animals; Brain; Brain Neoplasms; Enzyme Induction; Ethylnitrosourea; Female; Glucocorticoids; Glycerolphosphate Dehydrogenase; Hydrocortisone; Liver; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Tyrosine Transaminase | 1977 |
[Prenatal induction of hepatocellular glycogen storage areas and tumors in mice by ethylnitrosourea (author's transl)].
Topics: Animals; Endoplasmic Reticulum; Ethylnitrosourea; Female; Histocytochemistry; Liver Glycogen; Liver Neoplasms, Experimental; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Microscopy, Electron; Nitrosourea Compounds; Pregnancy | 1979 |
[Study of the immunological specificity of transplacentally induced neurinomas in rats].
Topics: Animals; Antigens, Neoplasm; Epitopes; Ethylnitrosourea; Female; Immunoelectrophoresis; Neoplasm Transplantation; Neurilemmoma; Placenta; Pregnancy; Rats | 1975 |
Chromosome analysis of experimental rat glial tumor(1)--correlation of chromosome changes between glial tumors and fetal brain tissue of rats after a transplacental exposure to ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Chromosomes; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
[Experimental brain tumors induced by transplacental administration of ethylnitrosourea. (2) Vascular constitution of experimental brain tumors].
Topics: Animals; Bleomycin; Brain Neoplasms; Cerebral Angiography; Cobalt Radioisotopes; Ethylnitrosourea; Female; Hydrocortisone; Maternal-Fetal Exchange; Microradiography; Neoplasms, Experimental; Nitrosourea Compounds; Photometry; Pregnancy; Rats | 1977 |
[Experimental brain tumors produced transplacentally by ethylnitrosourea (IV) (author's transl)].
Topics: Animals; Bleomycin; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Hydrocortisone; Maternal-Fetal Exchange; Methylprednisolone; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
Transplacental carcinogenesis.
Topics: Animals; Ethylnitrosourea; Female; Fetal Diseases; Maternal-Fetal Exchange; Neoplasms, Experimental; Neoplasms, Germ Cell and Embryonal; Nitrosourea Compounds; Opossums; Pregnancy | 1976 |
[Various aspects of transplacental blastomogenesis in rabbits].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Ethylnitrosourea; Female; Kidney Neoplasms; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Neurilemmoma; Pregnancy; Rabbits; Sciatic Nerve | 1978 |
Transplacental effects of ethylnitrosourea in a nonhuman primate, Erythrocebus patas.
Topics: Animals; Carcinogens; Cerebral Ventricles; Erythrocebus patas; Ethylnitrosourea; Female; Fetus; Haplorhini; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Tissue Distribution | 1979 |
Strand breakage in rat brain DNA and its repair induced by ethylnitrosourea in vivo.
Topics: Animals; Animals, Newborn; Brain; Brain Neoplasms; DNA; DNA Repair; Ethylnitrosourea; Female; Fetus; Nitrosourea Compounds; Nucleic Acid Conformation; Pregnancy; Rats | 1975 |
Experimental induction of melanotic tumors in syrian golden hamsters by transplacental and topical application of ethylnitrosourea.
Topics: Animals; Cricetinae; Ethylnitrosourea; Female; Male; Melanoma; Mesocricetus; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Pregnancy, Animal; Skin Neoplasms | 1977 |
Oncogenic properties of transplacentally acting ethyl-nitrosourea in NMRI-mice after antecedent X-irradiation.
Topics: Animals; Body Weight; Ethylnitrosourea; Female; Fetus; Male; Maternal-Fetal Exchange; Mice; Neoplasms; Nitrosourea Compounds; Pregnancy; X-Rays | 1978 |
Macrophages in brain tumours induced transplacentally by N-ethyl-N-nitrosourea in rats: an electron-microscope study.
Topics: Animals; Brain Edema; Brain Neoplasms; Cerebral Hemorrhage; Ethylnitrosourea; Female; Glioma; Inclusion Bodies; Leukocytes; Lipids; Lysosomes; Macrophages; Microscopy, Electron; Mitosis; Monocytes; Myelin Sheath; Necrosis; Nerve Degeneration; Nitrosourea Compounds; Phagocytosis; Pregnancy; Rats | 1975 |
[Transplacental oncogenic effect of ethylnitrosourea in rabbits (author's transl)].
Topics: Adenocarcinoma; Animals; Carcinosarcoma; Ethylnitrosourea; Female; Gestational Age; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms; Neoplasms, Germ Cell and Embryonal; Nitrosourea Compounds; Pregnancy; Rabbits; Sarcoma; Time Factors | 1975 |
Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Ethylnitrosourea; Female; Fetal Diseases; Glioma; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats | 1976 |
Transplacental effects of ethylnitrosourea precursors ethylurea and sodium nitrite in hamsters.
Topics: Animals; Cricetinae; Estrogens; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Mesocricetus; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Nitrites; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Sex Factors; Urea | 1976 |
The fine structure of blood vessels in ethylnitrosourea-induced tumours of the rat nervous system: with special reference to the breakdown of the blood-brain barrier.
Topics: Animals; Basement Membrane; Blood-Brain Barrier; Capillaries; Ethylnitrosourea; Female; Glioma; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neurilemmoma; Pregnancy; Rats | 1976 |
Effects of ethylnitrosourea administration during pregnancy on three subsequent generations of BDVI Rats.
Topics: Animals; Body Weight; Ethylnitrosourea; Female; Fetus; Kidney Neoplasms; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Nitrosourea Compounds; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains | 1977 |
[Transplacental induction of neurogenic tumors in rabbits (author's transl)].
Topics: Animals; Animals, Newborn; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neurilemmoma; Nitrosourea Compounds; Placenta; Pregnancy; Pregnancy, Animal; Rabbits; Time Factors | 1977 |
Morphologic and biochemical characteristics of transplantable neurogenic tumors induced by N-ethyl-N-nitrosourea in inbred BD IX rats.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain Neoplasms; Clone Cells; Ethylnitrosourea; Female; Glioma; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Rats, Inbred Strains; S100 Proteins; Transplantation, Isogeneic | 1979 |
Nitrosourea-induced brain tumors: an in vivo and in vitro tumor model system.
Topics: Animals; Brain Neoplasms; Cell Division; Cells, Cultured; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Immunosuppression Therapy; Male; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Thymus Gland; Time Factors; Transplantation, Isogeneic | 1978 |
Analysis of N-ethyl-N-nitrosourea-induced brain carcinogenesis by sequential culturing during the latent period. I. Morphology and tumorigenicity of the cultured cells and their growth in agar.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred Strains; Time Factors | 1978 |
Analysis of N-ethyl-N-nitrosourea-induced brain carcinogenesis by sequential culturing during the latent period. II. Morphology of the tumors induced by cell cultures.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Isogeneic | 1978 |
Surface structure of fetal rat brain cells during neoplastic transformation in cell culture.
Topics: Animals; Brain Neoplasms; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Microscopy, Electron, Scanning; Neoplasms, Experimental; Precancerous Conditions; Pregnancy; Rats; Time Factors | 1978 |
Transmission electron microscopy of fetal rat brain cells during neoplastic transformation in cell culture.
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
N-ethyl-N-nitrosourea-induced spinal tumors in an inbred strain of W albino rats.
Topics: Animals; Animals, Newborn; Astrocytoma; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1979 |
[Induction of tumours by different endogenously formed N-nitroso-ureas in the hooded rat (author's transl)].
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Lymphoma, Large B-Cell, Diffuse; Maternal-Fetal Exchange; Neoplasms; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Trigeminal Nerve | 1977 |
Tumors in two generations of mice in different environmental conditions.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Lactation; Leukemia, Experimental; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Pregnancy | 1977 |
Immune surveillance and tumors of the nervous system.
Topics: Animals; Antilymphocyte Serum; BCG Vaccine; Central Nervous System; Ethylnitrosourea; Female; Hypersensitivity, Delayed; Immunity; Immunosuppression Therapy; Neoplasms; Nervous System Diseases; Pregnancy; Rats; Skin Transplantation; Thymectomy; Transplantation, Homologous | 1978 |
[On the transplacental induction of tumours by N-ethyl--N-nitrosourea in different species (author's transl)].
Topics: Animals; Cricetinae; Dogs; Ethylnitrosourea; Female; Guinea Pigs; Haplorhini; Kidney Neoplasms; Macaca mulatta; Maternal-Fetal Exchange; Neoplasms; Nervous System Diseases; Nitrosourea Compounds; Ovarian Neoplasms; Placenta; Pregnancy; Rabbits; Rats; Thyroid Neoplasms | 1977 |
[Experiments on rhesus-monkeys (Macaca mulatta) with the carcinogens methyl- and ethylnitrosourea (author's transl)].
Topics: Animals; Ethylnitrosourea; Female; Fetus; Haplorhini; Macaca mulatta; Male; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Time Factors | 1977 |
Neuroblasts in cerebral tumors induced by ethylnitrosourea in rats. A fine structrual study.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Medulla Oblongata; Neoplasms, Experimental; Neuroglia; Neurons; Organoids; Pregnancy; Rats | 1977 |
[Comparative study of the action of carcinogenic substances that induce transplacental blastomogenesis in rabbits].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Carcinogens; Ethylnitrosourea; Female; Male; Methylnitrosourea; Neoplasms, Experimental; Neurilemmoma; Placenta; Pregnancy; Rabbits; Time Factors | 1978 |
The development of experimental brain tumours. A sequential light and electron microscope study of the subependymal plate. I. Early lesions (abnormal cell clusters).
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
The development of experimental brain tumours a sequential light and electron microscope study of the subependymal plate. II. Microtumours.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
Immunization against ethylnitrosourea-induced autochthonous neurogenic rat tumours.
Topics: Animals; Antigens, Neoplasm; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Immunization; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred F344 | 1979 |
[Characteristics of the action of N-nitrosoethylurea in rat embryogenesis].
Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Drug Resistance; Embryo, Mammalian; Ethylnitrosourea; Female; Gestational Age; Neoplasms, Experimental; Nervous System Diseases; Nitrosourea Compounds; Pregnancy; Rats; Teratogens | 1979 |
The fine structure of stratified ependyma in the ventricular wall of N-ethyl-N-nitrosourea-treated rats.
Topics: Animals; Cell Differentiation; Cerebral Ventricles; Ependyma; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats | 1979 |
Tumor development in lung of ddY mice following transplacental exposure to 1-ethyl-1-nitrosourea.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Gestational Age; Injections, Intraperitoneal; Injections, Intravenous; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Time Factors; Urethane | 1979 |
An aberrant nucleus in the telencephalon following administration of ENU during neuroembryogenesis.
Topics: Animals; Cell Movement; Cerebral Cortex; Corpus Callosum; Ethylnitrosourea; Female; Gestational Age; Neurons; Nitrosourea Compounds; Pregnancy; Rats; Telencephalon | 1979 |
Induction of tumors by direct injection of N-ethyl-N-nitrosourea into the amniotic space of the mouse fetus.
Topics: Adenoma; Amnion; Animals; Drug Evaluation, Preclinical; Ethylnitrosourea; Female; Fetus; Gestational Age; Injections; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy | 1979 |
Teratogenic and carcinogenic effects of some chemicals during perinatal life in rats, Syrian golden hamsters, and minipigs.
Topics: Animals; Brain Neoplasms; Carcinogens; Cricetinae; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mesocricetus; Neoplasms, Experimental; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms; Swine; Teratogens | 1979 |
Role of hormone imbalance in transplacental carcinogenesis induced in Syrian golden hamsters by sex hormones.
Topics: Animals; Castration; Cricetinae; Diethylstilbestrol; Ethylnitrosourea; Female; Genital Neoplasms, Female; Gonadal Steroid Hormones; Male; Maternal-Fetal Exchange; Mesocricetus; Neoplasms, Experimental; Nitrosourea Compounds; Ovary; Peripheral Nervous System Neoplasms; Pregnancy; Testicular Neoplasms; Testis | 1979 |
Cerebral tumours induced by ENU; changes of adenylate cyclase activity in the tumour latency time.
Topics: Adenylyl Cyclases; Animals; Brain Neoplasms; Brain Stem; Ethylnitrosourea; Female; Frontal Lobe; Glioma; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats; Temporal Lobe | 1979 |
Fc gamma receptors receptors on fetal rat brain cells during neoplastic transformation in culture after exposure to ethylnitrosourea in vivo.
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Receptors, Fc | 1979 |
[Experimental brain tumor produced transplacentally by ethylnitrosourea (3). Autoradiographic studies on tumor cell proliferation].
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; DNA, Neoplasm; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
[Effect of N-nitrosoethylurea dosage and postnatal x-ray irradiation on transplacental blastomogenesis in mice].
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Fetus; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nitrosourea Compounds; Ovarian Neoplasms; Placenta; Pregnancy | 1977 |
Myelin lipids in the brain after transplacental intoxication with ethylnitrosourea.
Topics: Animals; Brain Chemistry; Cerebrosides; Ethylnitrosourea; Female; Lipids; Male; Maternal-Fetal Exchange; Mice; Myelin Sheath; Nitrosourea Compounds; Plasmalogens; Pregnancy; Sulfoglycosphingolipids | 1978 |
[Effect of irradiation to carcinogenesis by transplacental ethylnitrosourea in BD--IX rat (author's transl)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain Neoplasms; Cerebral Cortex; Embryo, Mammalian; Ethylnitrosourea; Female; Glioma; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats | 1978 |
[Ezymohistochemical study of the early stages of carcinogenesis in the rat peripheral nervous system].
Topics: Animals; Ethylnitrosourea; Female; Neoplasms, Experimental; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Schwann Cells; Time Factors; Trigeminal Nerve | 1977 |
Chemotherapy studies of various nitrosoureas: prevention of development of ethylnitrosourea-induced tumors in the nervous system.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred F344 | 1977 |
Cerebral tumors induced by transplacental ENU: study of the different tumoral stages, particularly of early proliferations.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Time Factors | 1978 |
Transplacental exposure to ethylnitrosourea and its effects on body, brain, and cerebellar development in the rat.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Cerebellum; Ethylnitrosourea; Female; Fetus; Gestational Age; Litter Size; Male; Maternal-Fetal Exchange; Nitrosourea Compounds; Organ Size; Pregnancy; Rats | 1978 |
[Combined transplacental carcinogenic action of N-nitrosomethylurea (NMU) and N-nitrosoethylurea (NEU) in rats].
Topics: Animals; Brain Neoplasms; Carcinogens; Dose-Response Relationship, Drug; Drug Interactions; Ethylnitrosourea; Female; Gestational Age; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Rats; Teratogens | 1978 |
[Early stages of experimental brain tumours in rats. Investigation of serial sections (author's transl)].
Topics: Animals; Astrocytoma; Basal Ganglia; Brain Neoplasms; Brain Stem; Cerebral Cortex; Ethylnitrosourea; Female; Glioma; Hippocampus; Neoplasms, Experimental; Oligodendroglioma; Pregnancy; Rats; Sarcoma; Time Factors | 1978 |
Enhanced development of mammary tumors in rats following transplacental and neonatal exposure to ethylnitrosourea.
Topics: Adenocarcinoma; Adenofibroma; Animals; Animals, Newborn; Cystadenoma; Ethylnitrosourea; Female; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats; Sarcoma, Experimental; Sex Factors; Time Factors | 1978 |
The significance of some modifying factors during transplacental blastomogenesis by ethylnitrosourea in rabbits.
Topics: Animals; Antigens; Ethylnitrosourea; Female; Kidney Neoplasms; Male; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Nerve Tissue; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Physical Stimulation; Pregnancy; Rabbits; Sciatic Nerve | 1978 |
[Experimental brain tumors produced transplacentally by ethylnitrosourea (IV): ultrastructure studied by using transmission and scanning electron microscope (author's transl)].
Topics: Animals; Cerebral Ventricle Neoplasms; Cerebral Ventricles; Ethylnitrosourea; Female; Glioma; Microscopy, Electron, Scanning; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Rats | 1978 |
[Organ cultures of embryonal rat brain tissue (hippocampal area) in a study of the transplacental effect of nitrosoethylurea].
Topics: Adenoma; Animals; Brain Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Hippocampus; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Organ Culture Techniques; Organ Specificity; Pregnancy; Rats | 1978 |
The effect of transplacental intoxication with ethylnitrosourea on myelin proteins.
Topics: Age Factors; Animals; Brain; Brain Chemistry; Electrophoresis, Polyacrylamide Gel; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mice; Myelin Proteins; Nitrosourea Compounds; Pregnancy; Pregnancy Complications | 1978 |
Influence of five different postnatal lifelong treatments on the transplacental carcinogenicity of ethylnitrosourea in Sprague-Dawley rats.
Topics: Albumins; Animals; BCG Vaccine; Brain Neoplasms; Cyclophosphamide; Ethylnitrosourea; Female; Hydrocortisone; Immunotherapy; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Mycobacterium bovis; Neoplasms, Experimental; Nicotine; Nitrosourea Compounds; Pregnancy; Rats; Spinal Neoplasms | 1976 |
Some results and prospects of transplacental carcinogenesis studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Nervous System Diseases; Nitrosourea Compounds; Organ Specificity; Placenta; Pregnancy; Rats | 1976 |
Screening of potential chemical carcinogens by means of mammalian cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cells, Cultured; Cricetinae; DDT; Diethylnitrosamine; Dimethylnitrosamine; Drug Evaluation, Preclinical; Ethylnitrosourea; Female; Guinea Pigs; In Vitro Techniques; Methylnitrosourea; Mice; Neoplasms, Experimental; Pregnancy; Rats | 1976 |
Prenatal multicarcinogenesis by ethylnitrosourea in mice.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ethylnitrosourea; Female; Fetus; Gestational Age; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Ovarian Neoplasms; Peripheral Nervous System Neoplasms; Pregnancy; Sex Factors; Stomach Neoplasms | 1977 |
The role of the subependymal plate in the origin of gliomas induced by ethylnitrosourea in the rat brain.
Topics: Animals; Brain; Brain Neoplasms; Corpus Callosum; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Neurons; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
[Tumors in BALB C mice after transplacental exposure to N-nitrosoethylurea in progenesis].
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Ethylnitrosourea; Female; Fetus; Leydig Cell Tumor; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Testicular Neoplasms | 1977 |
[Effect of neurotropic carcinogenic agents nitrosomethyl- and nitrosoethylurea on rat embryo cerebral cortex development].
Topics: Animals; Brain; Brain Diseases; Cerebral Cortex; Ethylnitrosourea; Female; Gestational Age; Maternal-Fetal Exchange; Methylnitrosourea; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
Common tumor-associated transplantation alloantigen detected on a proportion of lung tumors induced transplacentally in several strains of mice.
Topics: Animals; Antigens, Neoplasm; Cross Reactions; Ethylnitrosourea; Female; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy | 1977 |
A sequential in vivo-in vitro study of carcinogenesis induced in the rat brain by ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Glioma; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
[Cytogenetic characteristics of lung tumors induced by exposing BALB/C mice to transplacental N-nitrosoethylurea].
Topics: Adenocarcinoma; Animals; Chromosomes; Ethylnitrosourea; Female; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrosourea Compounds; Ploidies; Pregnancy | 1976 |
The origin of experimental brain tumours: a sequential study.
Topics: Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
Susceptibility of fetal lung to transplacental 1-ethyl-1-nitrosourea: its relation to epithelial proliferation.
Topics: Adenoma; Animals; Cell Division; Epithelial Cells; Ethylnitrosourea; Female; Gestational Age; Lung; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Nitrosourea Compounds; Pregnancy | 1976 |
Light and electron microscopic investigations on a transplantable tumour of the rat, induced by transplacental administration of ENU (ethylnitrosourea).
Topics: Anaplasia; Animals; Ethylnitrosourea; Female; Lymphatic Metastasis; Maternal-Fetal Exchange; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
[Experimental brain neoplasm induced transplacentally by ethylnitrosourea (ENU). (1) Sequential, localized observations and pathological studies of microtumors].
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats | 1976 |
[Experimental brain neoplasm induced by ethylnitrosourea. Frequency of incidence and neurological manifestation in rats].
Topics: Aggression; Animals; Astrocytoma; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Humans; Meningioma; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Trigeminal Nerve | 1976 |
Sequential development of ethylnitrosourea-induced neurinomas: morphology, biochemistry, and transplantability.
Topics: Age Factors; Animals; Animals, Newborn; Ethylnitrosourea; Female; Fetus; Glucuronidase; Hexosaminidases; Neoplasm Transplantation; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Trigeminal Nerve | 1975 |
Transplacental induction of primary renal tumors in rabbits treated with 1-ethyl-1-nitrosourea.
Topics: Animals; Blood Cell Count; Cystadenoma; Cysts; Ethylnitrosourea; Female; Genotype; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rabbits; Time Factors | 1975 |
Effects of nerve growth factor administration of N-ethyl-N-nitrosourea carcinogenesis.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Male; Methylcholanthrene; Neoplasms, Experimental; Nerve Growth Factors; Neuroblastoma; Nitrosourea Compounds; Pregnancy; Rats; Urogenital Neoplasms | 1975 |
Problems in transplacental carcinogenesis.
Topics: Animals; Brain Neoplasms; Ependymoma; Ethylnitrosourea; Female; Fetal Diseases; Maternal-Fetal Exchange; Neoplasms; Neoplasms, Experimental; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms | 1975 |
Neoplastic transformation of fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo.
Topics: Animals; Brain; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Models, Biological; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Time Factors | 1975 |
Inhibitory effect of sodium ascorbate on ethylurea and sodium nitrite carcinogensis and negative findings in progeny after intestinal inoculation of precursors into pregnant hamsters.
Topics: Animals; Ascorbic Acid; Astrocytoma; Brain Neoplasms; Cecum; Cricetinae; Ethylnitrosourea; Female; Intubation, Gastrointestinal; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrites; Nitroso Compounds; Peripheral Nervous System Neoplasms; Pons; Pregnancy; Sex Factors; Urea | 1975 |
[Teratogenic action of ethyl-nitrosourea in Göttingen miniature pigs (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Bone Development; Ethylnitrosourea; Female; Forelimb; Gestational Age; Maxilla; Nitrosourea Compounds; Pregnancy; Spine; Swine; Teratogens | 1975 |
Oncogenic response of rats with x-ray-induced microcephaly to transplacental ethylnitrosourea.
Topics: Animals; Ependymoma; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Peripheral Nervous System Neoplasms; Pregnancy; Radiation Injuries, Experimental; Rats; Time Factors | 1976 |
[The inhibiting effect of epsilon-aminocaproic acid on the incidence of induced tumors of the esophagus, nervous system and kidneys].
Topics: Aminocaproic Acid; Animals; Anticarcinogenic Agents; Carcinogens; Chi-Square Distribution; Dimethylnitrosamine; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Ethylnitrosourea; Female; Incidence; Kidney Neoplasms; Male; Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1992 |
[The anticarcinogenic effects of fumaric acid on models of carcinogenesis in the esophagus, nervous system and kidney].
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Chi-Square Distribution; Dimethylnitrosamine; Disease Models, Animal; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Ethylnitrosourea; Female; Fumarates; Kidney Neoplasms; Male; Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1992 |
[The inhibiting effect of phytoadaptogenic preparations from bioginseng, Eleutherococcus senticosus and Rhaponticum carthamoides on the development of nervous system tumors in rats induced by N-nitrosoethylurea].
Topics: Animals; Antineoplastic Agents, Phytogenic; Chi-Square Distribution; Drug Screening Assays, Antitumor; Ethylnitrosourea; Female; Kidney Neoplasms; Nervous System Neoplasms; Panax; Phytotherapy; Plant Extracts; Plants, Medicinal; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Time Factors | 1992 |
Biochemical characterization of a variant form of cytosolic epoxide hydrolase induced by parental exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Blotting, Western; Chromatography, Affinity; Clofibrate; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Epoxide Hydrolases; Ethylnitrosourea; Female; Isoelectric Point; Mice; Mice, Inbred BALB C; Oxidoreductases; Pregnancy | 1992 |
N-alkyl-N-nitrosourea induced secondary structural changes in DNA from rat embryos and fetal brains in vivo.
Topics: Abnormalities, Drug-Induced; Animals; Brain; DNA; Embryo, Mammalian; Ethylnitrosourea; Female; Fetus; Methylnitrosourea; Neoplasms, Experimental; Nucleic Acid Conformation; Pregnancy; Rats; Rats, Wistar | 1992 |
Angiogenic activity of the K-fgf/hst oncogene in neural transplants.
Topics: Animals; Antisense Elements (Genetics); Brain Neoplasms; Brain Tissue Transplantation; Caudate Nucleus; Endothelium, Vascular; Ethylnitrosourea; Female; Fetal Tissue Transplantation; Fetus; Fibroblast Growth Factor 4; Fibroblast Growth Factors; Growth Substances; Humans; Injections; Neovascularization, Pathologic; Neurons; Oncogenes; Placenta; Pregnancy; Proto-Oncogene Proteins; Putamen; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, Fibroblast Growth Factor; Retroviridae; Transfection | 1992 |
Expression of neuronal markers in the so-called ENU-induced schwannomas.
Topics: Animals; Axons; Biomarkers; Endoplasmic Reticulum; Ethylnitrosourea; Female; Immunoenzyme Techniques; Maternal-Fetal Exchange; Microscopy, Electron; Myelin Sheath; Neurilemmoma; Neurofilament Proteins; Pregnancy; Rats; Rats, Wistar; Schwann Cells; Spinal Cord Neoplasms; Synaptophysin | 1992 |
Immunohistochemical observations on rat radial glia: relationship with the origin of ethylnitrosourea-induced tumors.
Topics: Animals; Astrocytes; Brain Neoplasms; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Microscopy, Immunoelectron; Neuroglia; Pregnancy; Rats; Rats, Inbred F344; Vimentin | 1992 |
Synaptophysin expression in "ependymal tumors" induced by ethyl-nitrosourea in rats.
Topics: Animals; Brain Neoplasms; Ependyma; Ependymoma; Ethylnitrosourea; Female; Immunohistochemistry; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Wistar; Synaptophysin | 1992 |
High susceptibility of analbuminemic rats to neurogenic tumor induction by transplacental administration of N-ethyl-N-nitrosourea.
Topics: Animals; Brain Neoplasms; Disease Susceptibility; DNA, Neoplasm; Ethylnitrosourea; Female; Guanine; Injections, Subcutaneous; Male; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1992 |
A preliminary investigation of promotion of brain tumours by hexachlorophane in Sprague-Dawley rats transplacentally exposed to N-ethylnitrosourea.
Topics: Animals; Body Weight; Brain; Brain Edema; Brain Neoplasms; Carcinogens; Cocarcinogenesis; Eating; Ethylnitrosourea; Female; Hexachlorophene; Maternal-Fetal Exchange; Organ Size; Pregnancy; Rats; Rats, Inbred Strains | 1992 |
Study of postnatal effects of chemopreventive agents on offspring of ethylnitrosourea-induced transplacental carcinogenesis in rats. I. Influence of retinol acetate, alpha-tocopherol acetate, thiamine chloride, sodium selenite, and alpha-difluoromethylorn
Topics: alpha-Tocopherol; Animals; Antioxidants; Diterpenes; Eflornithine; Ethylnitrosourea; Female; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms, Experimental; Nervous System Neoplasms; Pregnancy; Rats; Retinyl Esters; Selenium; Sodium Selenite; Thiamine; Tocopherols; Vitamin A; Vitamin E; Vitamins | 1991 |
Immunochemistry of ethylnitrosourea-induced rat neurinomas, the RN6 neurinoma cell line and their transplantation tumors.
Topics: Animals; Antigens, Differentiation; CD57 Antigens; Cell Line; Ethylnitrosourea; Female; Fibronectins; Glial Fibrillary Acidic Protein; Immunohistochemistry; Mice; Mice, Inbred Strains; Myelin Basic Protein; Neoplasm Transplantation; Nervous System Neoplasms; Neurilemmoma; Pregnancy; Rats; Rats, Inbred Strains; S100 Proteins; Vimentin | 1991 |
Relationship between glial reaction to a stab wound and tumor development after receiving transplacental ethylnitrosourea in the rat.
Topics: Animals; Brain; Bromodeoxyuridine; Ethylnitrosourea; Female; Injections; Maternal-Fetal Exchange; Neoplasms, Experimental; Neuroglia; Phenotype; Pregnancy; Rats; Rats, Inbred F344; Wounds, Stab | 1991 |
Simultaneous induction of mutagenic and cancerogenic effects in T x HT mice with transplacental ethylnitrosourea treatment.
Topics: Animals; Carcinogens; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Mice; Mosaicism; Mutagens; Mutation; Neoplasms, Experimental; Pregnancy | 1990 |
The paternal genome in mouse zygotes is less sensitive to ENU mutagenesis than the maternal genome.
Topics: Animals; Cell Survival; DNA; Ethylnitrosourea; Female; Gene Expression; Male; Mice; Mutation; Oocytes; Pregnancy; Sex Factors; Spermatozoa; Time Factors; Zygote | 1991 |
Transplacental induction of mouse lung tumors: stage of fetal organogenesis in relation to frequency, morphology, size, and neoplastic progression of N-nitrosoethylurea-induced tumors.
Topics: Animals; Ethylnitrosourea; Female; Fetal Diseases; Gestational Age; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Pregnancy | 1991 |
[The carcinogenic activity of N-nitroso-N-ethylurea in kidney organ cultures of mice exposed transplacentally to cobalamin coenzymes and folinic acid].
Topics: Animals; Cobamides; Epithelium; Ethylnitrosourea; Female; Hyperplasia; Kidney; Leucovorin; Mice; Organ Culture Techniques; Placenta; Pregnancy; Time Factors; Vitamin B 12 | 1991 |
Regional distribution study of brain perfusion and metabolic agents in normal and tumour bearing rat brains using autoradiographic technique.
Topics: Amphetamines; Animals; Autoradiography; Brain; Brain Chemistry; Brain Neoplasms; Ethylnitrosourea; Female; Glucose; Iodine Radioisotopes; Iodobenzenes; Iofetamine; Methionine; Neoplasms, Experimental; Perfusion; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Renal tubular cell or hepatocyte hyperplasia is not associated with tumor promotion by di(2-ethylhexyl)phthalate in B6C3F1 mice after transplacental initiation with N-nitrosoethylurea.
Topics: Animals; Bromodeoxyuridine; Diethylhexyl Phthalate; DNA; Ethylnitrosourea; Female; Hyperplasia; Kidney Neoplasms; Kidney Tubules; Liver; Liver Neoplasms, Experimental; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Pregnancy | 1990 |
Immunohistochemical investigations in experimentally induced tumors of the nervous system.
Topics: Animals; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Intermediate Filament Proteins; Neurofilament Proteins; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms; Survival Rate; Vimentin | 1990 |
Suppression of 6-TG-resistant mutations in V79 cells and recessive spot formations in mice by vanillin.
Topics: Acrolein; Animals; Benzaldehydes; Cells, Cultured; Coumarins; Drug Resistance; Ethylnitrosourea; Female; Male; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutation; Pregnancy; Thioguanine; Ultraviolet Rays; X-Rays | 1990 |
Diaplacental induction by ethylnitrosourea of tumours at the pial border of the central nervous system in (T X HT)F1 mice.
Topics: Animals; Brain Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Fetal Diseases; Fetus; Male; Maternal-Fetal Exchange; Meninges; Mice; Peripheral Nervous System Neoplasms; Pregnancy; Skull Neoplasms | 1990 |
[Synthesis and animal experiments of ethylnitrosourea].
Topics: Animals; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glioma; Pregnancy; Rats; Rats, Inbred Strains; Trigeminal Nerve | 1990 |
Clara cell adenomas of the mouse lung. Interaction with alveolar type 2 cells.
Topics: Adenoma; Age Factors; Animals; Autoradiography; Bronchi; Cytoplasmic Granules; Ethylnitrosourea; Female; Histocytochemistry; Inclusion Bodies; Lung Neoplasms; Mice; Microscopy, Electron; Pregnancy; Pulmonary Alveoli; Staining and Labeling | 1985 |
Glial fibrillary acidic protein and vimentin in the experimental glial reaction of the rat brain.
Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Lasers; Nerve Crush; Pregnancy; Rats; Rats, Inbred F344; Staining and Labeling; Vimentin | 1986 |
Significance of modifying factors in the development of transplacental renal tumours in rabbits.
Topics: Animals; Antithyroid Agents; Dienestrol; Ethylnitrosourea; Female; Kidney Neoplasms; Methimazole; Nephrectomy; Ovariectomy; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Thyroid Hormones | 1989 |
Quantitative analysis of alveolar type II cell tumors in mice by whole lung serial and step sections.
Topics: Animals; Ethylnitrosourea; Female; Lung; Lung Neoplasms; Mice; Mice, Inbred C3H; Pregnancy; Staining and Labeling | 1989 |
Experimental model of tumors associated with neurofibromatosis.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Ethylnitrosourea; Female; Kidney Neoplasms; Neoplasms, Multiple Primary; Nervous System Neoplasms; Neurofibromatosis 1; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spinal Nerves; Trigeminal Nerve; Wilms Tumor | 1989 |
Renal tumors induced transplacentally in the rat by n-ethylnitrosourea.
Topics: Animals; Ethylnitrosourea; Female; Kidney Diseases, Cystic; Kidney Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Pregnancy; Rats; Rats, Inbred Strains; Wilms Tumor | 1989 |
Transplacental induction of peripheral nervous tumor in the Syrian golden hamster by N-nitroso-N-ethylurea. A new animal model for von Recklinghausen's neurofibromatosis.
Topics: Animals; Cricetinae; Disease Models, Animal; Ethylnitrosourea; Female; Fluorescent Antibody Technique; Immunohistochemistry; Maternal-Fetal Exchange; Melanoma; Mesocricetus; Microscopy, Electron; Neural Crest; Neurofibroma; Neurofibromatosis 1; Peripheral Nervous System Neoplasms; Pheochromocytoma; Pregnancy; S100 Proteins; Wilms Tumor | 1989 |
Acutely transforming retroviruses as carcinogens in mouse embryos.
Topics: Animals; Animals, Newborn; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; Embryo, Mammalian; Ethylnitrosourea; Female; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Sarcoma Viruses, Murine | 1989 |
Comparative transplacental carcinogenesis by directly acting and metabolism-dependent alkylating agents in rodents and nonhuman primates.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Carcinogens; Choriocarcinoma; Diethylnitrosamine; Erythrocebus patas; Ethylnitrosourea; Female; Male; Neoplasms, Experimental; Neoplasms, Germ Cell and Embryonal; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Uterine Neoplasms | 1989 |
Effect of nerve growth factor on the transplacental induction of neurinomas by ethylnitrosourea in Sprague-Dawley rats.
Topics: Animals; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Immunohistochemistry; Maternal-Fetal Exchange; Mice; Nerve Growth Factors; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Trigeminal Nerve | 1989 |
In vitro developmental toxicity of five direct-acting alkylating agents in rodent embryos: structure-activity patterns.
Topics: Alkylating Agents; Analysis of Variance; Animals; Brain; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Ethylnitrosourea; Female; In Vitro Techniques; Maternal-Fetal Exchange; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Pregnancy; Rats; Rats, Inbred Strains | 1989 |
Glomeruloid blood vessels in ethylnitrosourea-induced rat gliomas. Histological and immunohistochemical studies.
Topics: Animals; Blood Vessels; Brain Neoplasms; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioma; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; von Willebrand Factor | 1989 |
Phenobarbital lacks promoting activity for neurogenic tumors in F344 rats transplacentally exposed to ethylnitrosourea.
Topics: Animals; Astrocytes; Ethylnitrosourea; Female; Gestational Age; Glioma; Male; Maternal-Fetal Exchange; Nervous System Neoplasms; Neurilemmoma; Oligodendroglia; Oligodendroglioma; Phenobarbital; Placenta; Pregnancy; Rats; Rats, Inbred F344 | 1989 |
Relationship between in utero development of the mouse liver and tumor development following transplacental exposure to ethylnitrosourea.
Topics: Animals; Ethylnitrosourea; Female; Gestational Age; Liver; Liver Neoplasms; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Pregnancy | 1989 |
[The modifying influence of adenosylcobalamin on the transplacental carcinogenic effect of N-nitroso-N-ethylurea in organ cultures of the kidneys of DBA/2 mice].
Topics: Animals; Autoradiography; Cobamides; Drug Interactions; Embryo, Mammalian; Ethylnitrosourea; Female; Hyperplasia; Kidney; Kidney Neoplasms; Mice; Mice, Inbred DBA; Necrosis; Organ Culture Techniques; Placenta; Pregnancy | 1989 |
Craniofacial malformations induced by N-ethyl-N-nitrosourea in rat embryos in vivo and in vitro.
Topics: Abnormalities, Drug-Induced; Animals; Ethylnitrosourea; Facial Bones; Female; In Vitro Techniques; Pregnancy; Rats; Rats, Inbred Strains; Skull; Teratogens | 1989 |
Effect of chronic stress on ENU-induced tumors.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Pregnancy; Rats; Stress, Psychological | 1989 |
Cell-specific brain tumour induction in neural transplants: evidence for multistep carcinogenesis in the nervous system.
Topics: Animals; Brain; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Nerve Tissue; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344 | 1989 |
Effects of postnatal administration of tumour-promoting barbiturates on the development of tumours initiated by prenatal exposure of fetal rats and mice to N-alkylnitrosoureas.
Topics: Aging; Animals; Barbiturates; Carcinogens; Cocarcinogenesis; Ethylnitrosourea; Female; Male; Methylnitrosourea; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Sex Factors | 1989 |
Correlations between the degree and type of forebrain malformations and the simultaneous neuro-oncogenic properties of ethylnitrosourea after diaplacental exposure in rats, alone and in combination with X-irradiation.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1985 |
Glucocorticoid hormone effect on transplacental carcinogenesis and lung differentiation: influence of histocompatibility-2 complex.
Topics: Adenocarcinoma, Papillary; Animals; Embryonic and Fetal Development; Ethylnitrosourea; Female; Glucocorticoids; H-2 Antigens; Haplotypes; Intestinal Neoplasms; Intestine, Small; Lung; Lung Neoplasms; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Surfactants | 1989 |
Immunohistochemical studies on cellular character of microtumors induced by ethylnitrosourea in the rat brain utilizing anti-Leu 7 and anti-glial fibrillary acidic protein antibodies.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Histocytochemistry; Immunochemistry; Neoplasms, Germ Cell and Embryonal; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
Differential renal tumor response to N-ethylnitrosourea and dimethylnitrosamine in the Nb rat: basis for a new rodent model of nephroblastoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dimethylnitrosamine; Disease Models, Animal; Ethylnitrosourea; Female; Kidney Neoplasms; Male; Ovariectomy; Placenta; Pregnancy; Rats; Wilms Tumor | 1985 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on neurogenic microtumors initiated by transplacental exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cocarcinogenesis; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Oligodendroglioma; Placenta; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1987 |
A clonal marker induced by mutation in mouse intestinal epithelium.
Topics: Animals; Clone Cells; Epithelium; Ethylnitrosourea; Female; Genetic Markers; Intestinal Mucosa; Jejunum; Lectins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Plant Lectins; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Mitogen | 1988 |
Congenital defects in the offspring of male mice treated with ethylnitrosourea.
Topics: Animals; Congenital Abnormalities; Ethylnitrosourea; Female; Fetal Death; Male; Mice; Mice, Inbred ICR; Pregnancy; Spermatogonia; Spermatozoa | 1988 |
Establishment and characterization of an intracerebrally transplanted tumor line, induced experimentally in the spinal cord.
Topics: Animals; Brain Neoplasms; Cell Line; Ethylnitrosourea; Female; Neoplasm Transplantation; Nervous System Neoplasms; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1988 |
Mouse papillary lung tumors transplacentally induced by N-nitrosoethylurea: evidence for alveolar type II cell origin by comparative light microscopic, ultrastructural, and immunohistochemical studies.
Topics: Age Factors; Animals; Antigens; Carcinoma, Papillary; Ethylnitrosourea; Female; Fetus; Immunohistochemistry; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Microscopy, Fluorescence; Nitroblue Tetrazolium; Pregnancy; Pulmonary Surfactants; Rabbits | 1988 |
Effect of gestational development of lung tumor size and morphology in the mouse.
Topics: Animals; Body Weight; Ethylnitrosourea; Female; Fetus; Gestational Age; Lung; Lung Neoplasms; Male; Mice; Pregnancy | 1988 |
[Effect of tocopherol, phenformin and thymus and pineal polypeptide factors on the transplacental carcinogenic effect of N-nitroso-N-ethylurea in rats].
Topics: Animals; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Peptides; Phenformin; Pregnancy; Rats; Thymus Hormones; Vitamin E | 1988 |
Mutagen-induced fetal anomalies and death following treatment of females within hours after mating.
Topics: Abnormalities, Drug-Induced; Animals; Cleavage Stage, Ovum; Embryo Implantation; Ethyl Methanesulfonate; Ethylene Oxide; Ethylnitrosourea; Female; Fetal Death; Mice; Mutagens; Oocytes; Ovum; Pregnancy; Triethylenemelamine; Zygote | 1988 |
[Influence of the polypeptide preparations cortexin and encephalin on the transplacental carcinogenic effect of N-nitroso-N-ethylurea in rats].
Topics: Animals; Drug Evaluation, Preclinical; Drug Interactions; Enkephalins; Ethylnitrosourea; Female; Intercellular Signaling Peptides and Proteins; Male; Neoplasms, Experimental; Peptides; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1988 |
[Transzygotic carcinogenic effect of nitrosoethylurea in rats].
Topics: Animals; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Neoplasms, Experimental; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Time Factors; Zygote | 1988 |
[Selectivity of cell degeneration and histological peculiarities of the repair process in the developing rat spinal cord after ethylnitrosourea administration].
Topics: Animals; Ethylnitrosourea; Female; Microscopy, Electron; Nerve Degeneration; Nerve Regeneration; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spinal Cord; Spinal Cord Diseases | 1987 |
Activated neu oncogene sequences in primary tumors of the peripheral nervous system induced in rats by transplacental exposure to ethylnitrosourea.
Topics: Animals; Cell Line; DNA, Neoplasm; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Mutation; Oncogenes; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Rats, Inbred F344 | 1987 |
Postnatal development and neoplastic disease pattern in NMRI mice after combined treatment with ethylnitrosourea and X-irradiation on different days of the fetal period.
Topics: Animals; Cocarcinogenesis; Ethylnitrosourea; Female; Growth; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Pregnancy; Prenatal Exposure Delayed Effects; Time Factors | 1987 |
Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea.
Topics: Animals; Brain; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Genes; Glioma; Maternal-Fetal Exchange; Oncogenes; Platelet-Derived Growth Factor; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Rats | 1986 |
Effects of naltrexone in postnatal rats on the recovery of disturbed brain and lymphatic tissues after X-irradiation or ethylnitrosourea treatment in utero.
Topics: Aging; Animals; Body Weight; Brain; Ethylnitrosourea; Female; Male; Naltrexone; Organ Size; Pregnancy; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains | 1987 |
Induction of coat colour spots in non-agouti NMRI x PDB,Fl. Dose response relationship with ethylnitrosourea.
Topics: Animals; Crosses, Genetic; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Male; Mice; Mutagenicity Tests; Pigmentation; Pregnancy | 1986 |
Mutagenicity of 1,2-dibromo-3-chloropropane (DBCP) in the mouse spot test.
Topics: Animals; Crosses, Genetic; Ethylnitrosourea; Female; Genes, Recessive; Hair Color; Insecticides; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mutagenicity Tests; Mutation; Pregnancy; Propane | 1986 |
Induction of congenital malformations in the offspring of mutagen treated mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Mice; Mice, Inbred C3H; Mutagens; Pregnancy; Prenatal Exposure Delayed Effects | 1986 |
The relationship between hydrocephalus and Chiari type II malformation in the experimental rat fetuses with Arnold-Chiari malformation.
Topics: Abnormalities, Drug-Induced; Animals; Arnold-Chiari Malformation; Brain; Ethylnitrosourea; Female; Fetus; Hydrocephalus; Male; Neural Tube Defects; Pregnancy; Rats; Rats, Inbred Strains | 1986 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on the in vitro malignant transformation of fetal rat brain cells exposed in utero to ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Concanavalin A; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplastic Stem Cells; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1986 |
[Modifying effect of methylcobalamin in organ cultures of the mouse kidney when administered transplacentally in combination with N-nitrosoethylurea].
Topics: Animals; Cocarcinogenesis; Ethylnitrosourea; Female; Fetal Diseases; Kidney Neoplasms; Maternal-Fetal Exchange; Mice; Organ Culture Techniques; Precancerous Conditions; Pregnancy; Vitamin B 12 | 1986 |
Chemotherapy in intracerebrally transplanted tumors induced with transplacental administration of ethylnitrosourea in rats.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ethylnitrosourea; Female; Lomustine; Methylnitrosourea; Neoplasm Transplantation; Placenta; Pregnancy; Rats; Spinal Cord Neoplasms | 1986 |
Ethylnitrosourea-induced transplacental carcinogenesis in the mouse: tumor response, DNA binding, and adduct formation.
Topics: Adenoma; Animals; DNA; DNA Damage; Ethylnitrosourea; Female; Gestational Age; Liver Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Pregnancy; Tissue Distribution | 1987 |
Lack of evidence for skeletal abnormalities in offspring of mice exposed to ethylnitrosourea.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Ethylnitrosourea; Female; Genetic Variation; Male; Mice; Mice, Inbred Strains; Mutation; Nitrosourea Compounds; Phenotype; Pregnancy | 1985 |
Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Infertility, Male; Male; Mice; Mutagens; Mutation; Pregnancy; Spermatogonia; Spermatozoa; Stem Cells; Time Factors | 1985 |
Morphological maturation of tumor cells induced by ethylnitrosourea (ENU) in rat brains. II. On the tumors by administration of ENU in the mid-gestational stage.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; Astrocytoma; Brain Neoplasms; Cell Differentiation; DNA Replication; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1985 |
Morphological maturation of tumor cells induced by ethylnitrosourea (ENU) in rat brains. I. On the tumors by administration of ENU in the late gestational stage.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1985 |
[Influence of anticarcinogenic agents on the transplacental carcinogenic effect of N-nitroso-N-ethylurea].
Topics: Animals; Antineoplastic Agents; Drug Evaluation, Preclinical; Ethylnitrosourea; Female; Kidney Neoplasms; Male; Nervous System Neoplasms; Nitrosourea Compounds; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Time Factors | 1985 |
Differentiation markers (S-100, GFAP, NSE and D2) in fetal rat brain cells during malignant transformation in cell culture.
Topics: Animals; Antigens, Surface; Brain; Brain Chemistry; Brain Neoplasms; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Glial Fibrillary Acidic Protein; Nerve Tissue Proteins; Phosphopyruvate Hydratase; Pregnancy; Rats; Rats, Inbred Strains; S100 Proteins | 1985 |
Multifocal neoplasms of the nervous system induced with ethylnitrosourea in Wistar rats.
Topics: Animals; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Neoplasms, Multiple Primary; Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 1985 |
[Lysosomal enzymes in nitrosamine induced nervous system tumors of rats (author's transl)].
Topics: Acid Phosphatase; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Glucuronidase; Hexosaminidases; Lysosomes; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Sulfatases | 1974 |