ethylnitrosourea has been researched along with Lung Neoplasms in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 45 (62.50) | 18.7374 |
1990's | 12 (16.67) | 18.2507 |
2000's | 13 (18.06) | 29.6817 |
2010's | 2 (2.78) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Chiba, M; Fujino, T; Kobayashi, Y; Koga, T; Mitsudomi, T; Nishino, M; Ohara, S; Shimoji, M; Suda, K; Takemoto, T; Tomizawa, K | 1 |
Costa, DB; Jänne, PA; Kobayashi, SS; Lau, CJ; Mushajiang, M; Oxnard, GR; Paweletz, CP; Rangachari, D; Shpilsky, JE; To, C; VanderLaan, PA | 1 |
Chen, Z; Wu, W; Yang, J; Zhang, C; Zhang, G | 1 |
Bando, Y; Izumi, K; Kaneda, S; Nakai, T; Ogawa, H; Ohnishi, T; Shiota, H; Takahashi, T; Takizawa, T; Tsuchigauchi, T; Uehara, H | 1 |
Hirose, M; Imaoka, M; Kashida, Y; Mitsumori, K; Onodera, H; Ueda, M; Watanabe, T | 1 |
Cairns, J | 1 |
Anderson, MW; Bodon, N; Devereux, TR; Herzog, CR; Maronpot, RR; Massey, TE; Pittman, B; You, M | 1 |
Demant, P; Horlings, H | 1 |
Gorshkova, EV; Kaledin, VI; Kobzev, VF; Merkulova, TI | 1 |
Hioki, K; Hirose, M; Ishii, Y; Kanki, K; Kodama, Y; Kuroiwa, Y; Kurokawa, Y; Nishikawa, A; Nomura, T; Umemura, T | 1 |
Baginskaia, NV; Il'nitskaia, SI; Kaledin, VI; Kholodar', AV; Obut, TA | 1 |
Bogue, MA; Cheverud, JM; Edwin, D; Fenske, TS; Graubert, TA; Jarvis, JC; Mathews, V; McLeod, HL; McMahon, C; Minn, M; Province, MA | 1 |
Caillaud, D; Demidem, A; Madelmont, JC; Merle, P; Morvan, D | 1 |
Demant, P; Fijneman, RJ; Kakarlapudi, N; Quan, L; Vernooy, JH | 1 |
Fox, RR; Hard, GC | 1 |
Wrba, H | 1 |
Den Engelse, L; Oomen, LC; Van der Valk, MA | 1 |
Aleksandrov, VA; Bespalov, VG | 1 |
Callahan, GN; Giedlin, MA; Martin, WJ | 1 |
Choudhury, C; Durkin, H; Kauffman, SL; Seravalli, E | 1 |
Concetti, HF; Kitagawa, T; Sugano, H; Tsuchiya, E | 1 |
Nomura, T | 1 |
Demant, P; Emmelot, P; Hart, AA; Oomen, LC | 1 |
Dutter, A; Hacker-Rieder, A; Wrba, H | 1 |
Bedigian, HG; Crary, DD; Fox, RR; Meier, H | 1 |
Ito, A; Naito, M; Naito, Y | 1 |
Perez-Polo, JR; Vinores, SA | 1 |
Kauffman, SL | 2 |
Maat, B; van Bekkum, DW; van Zwieten, MJ; Vecht, CJ | 1 |
Itze, L; Mihailovich, N; Rao, KV; Vesselinovitch, SD | 1 |
Kauffman, SL; Sato, T | 1 |
Bierke, P; Ehrenberg, L; Granath, F; Rönnbäck, C; Segerbäck, D | 1 |
Ivanova, T; Konstantinov, H; Raikov, Z; Simeonova, M | 1 |
Demant, P; Fijneman, RJ; Oomen, LC; Snoek, M | 1 |
Chua, BH; Palmer, KC; Zhong, K | 1 |
Albain, KS; Crowley, JJ; Gandara, D; Griffin, B; Hutchins, L; Livingston, RB; O'Bryan, RM; Von Hoff, DD | 1 |
Rapp, UR; Storm, SM | 1 |
Anderson, LM; Diwan, BA; Ramakrishna, G; Sithanandam, G | 1 |
Demant, P; Fijneman, RJ; Hart, AA; Tripodis, N | 1 |
Mihailovich, N; Rao, KV; Vesselinovitch, SD | 2 |
Mookenthottathil, T | 1 |
Conliffe, MA; Gipson, TG; Imamura, M; Martin, WJ | 1 |
Alexander, L; Kauffman, SL; Sass, L | 1 |
Hata, T; Kawakubo, Y; Komiyama, K; Nishiyama, Y; Umezawa, I | 1 |
Mollner, T; Munhall, A; Rossi, L; Shubik, P | 1 |
Kolodin, VI; Likhachev, AIa; Napalkov, NP; Tomatis, L | 2 |
Pozharisskiĭ, KM | 1 |
Koka, M; Mihailovich, N; Rao, KV; Rice, JM; Vesselinovitch, SD | 1 |
Gipson, TG; Martin, WJ; Rice, JM | 1 |
Kolodin, VI; Lihachev, AIa; Napalkov, NP; Tomatis, L | 1 |
Conliffe, M; Dove, L; Friedman, R; Gipson, TG; Martin, WJ; Rice, JM | 1 |
Jones, EL; Searle, CE | 1 |
Gipson, TG; Martin, SE; Martin, WJ; Rice, JM | 1 |
Likhachev, AIa | 1 |
Nagashima, Y; Ohaki, Y; Sumino, K; Umeda, M | 1 |
Goldblatt, PJ; Gunning, WT; Stoner, GD | 1 |
Anderson, MW; Gunning, WT; Lineen, AM; Stoner, GD; Wang, Y; You, M | 1 |
Calafat, J; Demant, P; Egberts, J; Oomen, LC; Ten Have-Opbroek, AA | 1 |
Anderson, LM; Rehm, S; Rice, JM; Riggs, CW; Ward, JM | 1 |
Palmer, KC | 1 |
Rehm, S; Ward, JM | 1 |
Atassi, G; Bibby, MC; Double, JA; Dumont, P; McCormick, JE; McElhinney, RS; Pratesi, G; Radacic, M | 1 |
Demant, P; Hart, AA; Oomen, LC; van der Valk, MA | 1 |
Demant, P; Emmelot, P; Hart, AA; Oomen, LC; van der Valk, MA | 1 |
Anderson, LM; Katyal, SL; Rehm, S; Rice, JM; Singh, G; ten Have-Opbroek, AA; Ward, JM | 1 |
Branstetter, DG; Budd, C; Conran, PB; Goldblatt, PJ; Stoner, GD | 1 |
Schmahl, W | 1 |
Branstetter, DG; Conran, PB; Goldblatt, PJ; Schut, HA; Senitzer, D; Stoner, GD | 1 |
Herren-Freund, SL; Knutsen, GL; Pereira, MA | 1 |
3 review(s) available for ethylnitrosourea and Lung Neoplasms
Article | Year |
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Tumour susceptibility in mice in relation to H-2 haplotype.
Topics: Aging; Animals; Ethylnitrosourea; H-2 Antigens; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenotype; Species Specificity | 1983 |
Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis.
Topics: Animals; Animals, Newborn; Carcinogens; Ethylnitrosourea; Female; Gestational Age; Harderian Gland; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ovarian Neoplasms; Pregnancy; Risk; Stomach Neoplasms | 1979 |
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyrenes; Brain Neoplasms; Carcinogens; Cricetinae; Dimethylhydrazines; Dogs; Esophageal Neoplasms; Ethionine; Ethylnitrosourea; Female; Hematopoietic System; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosoguanidines; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms | 1975 |
1 trial(s) available for ethylnitrosourea and Lung Neoplasms
Article | Year |
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Predictors of survival following relapse or progression of small cell lung cancer. Southwest Oncology Group Study 8605 report and analysis of recurrent disease data base.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Ethylnitrosourea; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Thiotepa; Vincristine | 1993 |
68 other study(ies) available for ethylnitrosourea and Lung Neoplasms
Article | Year |
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Sensitivity and Resistance of MET Exon 14 Mutations in Lung Cancer to Eight MET Tyrosine Kinase Inhibitors In Vitro.
Topics: Alkylating Agents; Cell Transformation, Neoplastic; Cells, Cultured; Drug Resistance, Neoplasm; Ethylnitrosourea; Exons; Humans; In Vitro Techniques; Interleukin-3; Leukemia; Lung Neoplasms; Mutation; Precursor Cells, B-Lymphoid; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-met | 2019 |
EGFR-Mutated Lung Cancers Resistant to Osimertinib through EGFR C797S Respond to First-Generation Reversible EGFR Inhibitors but Eventually Acquire EGFR T790M/C797S in Preclinical Models and Clinical Samples.
Topics: Acrylamides; Alkylating Agents; Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cells, Cultured; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Ethylnitrosourea; Female; Gefitinib; Humans; Lung Neoplasms; Mice; Middle Aged; Mutagenesis; Mutation; Precursor Cells, B-Lymphoid; Protein Kinase Inhibitors; Retrospective Studies; Treatment Outcome | 2019 |
Differences in heating methods may account for variation in reported effects on gammaH2AX focus formation.
Topics: Animals; Biomarkers, Tumor; Cell Line; Cell Line, Tumor; Cells, Cultured; Chromosome Breakage; Cricetinae; DNA Breaks, Double-Stranded; Ethylnitrosourea; Flow Cytometry; Fluorescent Dyes; Gamma Rays; Histones; Hot Temperature; Humans; Hyperthermia, Induced; Lung Neoplasms; Temperature | 2009 |
Low susceptibility to N-ethyl-N-nitrosourea-induced transplacental carcinogenesis in Long-Evans Cinnamon (LEC) rats.
Topics: Animals; Base Sequence; Carcinogens; Ethylnitrosourea; Female; Liver; Lung Neoplasms; Male; Maternal-Fetal Exchange; Metallothionein; Nervous System Neoplasms; O(6)-Methylguanine-DNA Methyltransferase; Pregnancy; Rats; Rats, Inbred F344; Rats, Inbred LEC; Rats, Long-Evans; RNA, Messenger; Species Specificity | 2009 |
Tumor promoting effect of phenolphthalein on development of lung tumors induced by N-ethyl-N-nitrosourea in transgenic mice carrying human prototype c-Ha-ras gene.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Ethylnitrosourea; Female; Genes, ras; Humans; Immunohistochemistry; Lung Neoplasms; Mice; Mice, Transgenic; Phenolphthalein; Proliferating Cell Nuclear Antigen; Random Allocation | 2002 |
Somatic stem cells and the kinetics of mutagenesis and carcinogenesis.
Topics: Adult; Animals; Epithelial Cells; Ethylnitrosourea; Humans; Intestinal Mucosa; Kinetics; Lung Neoplasms; Male; Mice; Mutagenesis; Mutagens; Smoking; Stem Cells; Tumor Suppressor Protein p53 | 2002 |
Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression.
Topics: Adenocarcinoma; Animals; Carcinogens; Chromosomal Instability; Chromosome Deletion; Chromosome Mapping; Crosses, Genetic; Ethylnitrosourea; Loss of Heterozygosity; Lung; Lung Neoplasms; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Urethane | 2004 |
Lung tumor location and lymphocyte infiltration in mice are genetically determined.
Topics: Alkylating Agents; Animals; Bronchi; Drug Administration Schedule; Ethylnitrosourea; Female; Injections, Intraperitoneal; Lung; Lung Neoplasms; Lymphocytes; Mice; Mice, Inbred Strains; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Species Specificity | 2005 |
Codon 12 region of mouse K-ras gene is the site for in vitro binding of transcription factors GATA-6 and NF-Y.
Topics: Animals; Base Sequence; Binding Sites; CCAAT-Binding Factor; Codon; Ethylnitrosourea; GATA6 Transcription Factor; Genes, ras; Lung; Lung Neoplasms; Methylcholanthrene; Mice | 2005 |
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Antioxidants; Benzo(a)pyrene; Butylated Hydroxytoluene; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Disease Models, Animal; Ethylnitrosourea; Female; Humans; Incidence; Lung Neoplasms; Male; Methylcholanthrene; Mice; Mice, Transgenic; Oncogene Protein p21(ras) | 2006 |
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine].
Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Ethylnitrosourea; Female; Hypnotics and Sedatives; Leukemia; Lung Neoplasms; Male; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Phenobarbital; Thyroxine | 2005 |
Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.
Topics: Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Cocarcinogenesis; Ethylnitrosourea; Genetic Predisposition to Disease; Hematologic Neoplasms; Lung Neoplasms; Mice; Mice, Inbred Strains; Mutagens; Neoplasms, Experimental; Quantitative Trait Loci | 2006 |
CENU treatment induced bystander effects which are effective on parental and non-parental tumors and have a phospholipid metabolism proton NMR spectroscopy signature.
Topics: Animals; Bystander Effect; Carcinoma, Lewis Lung; Cell Differentiation; Ethylnitrosourea; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Nitroso Compounds; Phospholipids; Protons | 2006 |
Control of lymphocyte infiltration of lung tumors in mice by host's genes: mapping of four Lynf (lymphocyte infiltration) loci.
Topics: Animals; Carcinogens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Ethylnitrosourea; Genotype; Immunohistochemistry; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Transgenic; Neoplasms, Experimental; Polymorphism, Single-Stranded Conformational | 2008 |
Histologic characterization of renal tumors (nephroblastomas) induced transplacentally in IIIVO/J and WH/J rabbits by N-ethylnitrosourea.
Topics: Abdominal Neoplasms; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelium; Ethylnitrosourea; Female; Humans; Kidney Glomerulus; Kidney Neoplasms; Kidney Tubules; Lung Neoplasms; Maternal-Fetal Exchange; Neoplasms, Connective Tissue; Pregnancy; Rabbits; Wilms Tumor | 1983 |
Experimental cancer prophylaxis.
Topics: Adenoma; Animals; Diterpenes; Ethylnitrosourea; Female; Fetus; Leukemia, Experimental; Lung Neoplasms; Male; Methylcholanthrene; Mice; Peptide Hydrolases; Pregnancy; Retinyl Esters; Sarcoma, Experimental; Vitamin A; Water Supply | 1983 |
[Effect of selenium on transplacental carcinogenesis].
Topics: Animals; Drug Antagonism; Ethylnitrosourea; Female; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Selenium; Urethane | 1984 |
Identification of Ia antigens on the murine adenocarcinoma LT-85.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Cell Line; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Ethylnitrosourea; Histocompatibility Antigens Class II; Lung Neoplasms; Lymphocytes; Mice; Mice, Inbred Strains; Neuraminidase; Peptides; Trypsin | 1983 |
Lymphocytic infiltration of bronchioloalveolar adenomas in mice.
Topics: Adenoma; Animals; Ethylnitrosourea; Lung Neoplasms; Lymphocytes; Mice; Neoplasm Invasiveness; Pleural Neoplasms; Pulmonary Alveoli; Receptors, Antigen, B-Cell | 1983 |
Lack of promotion effect of phenobarbital on pulmonary tumorigenesis in ddy mice initiated by transplacental exposure to 1-ethyl-1-nitrosourea.
Topics: Animals; Ethylnitrosourea; Female; Lung; Lung Neoplasms; Male; Mice; Nitrosourea Compounds; Phenobarbital; Placenta; Pregnancy; Prenatal Exposure Delayed Effects | 1984 |
Timing of chemically induced neoplasia in mice revealed by the antineoplastic action of caffeine.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; DNA Repair; Ethylnitrosourea; Female; Hydroxamic Acids; Lung Neoplasms; Maternal-Fetal Exchange; Methylnitrosourea; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Nitroquinolines; Pregnancy; Time Factors; Urethane | 1980 |
Multiple genes in the H-2 complex affect differently the number and growth rate of transplacentally induced lung tumours in mice.
Topics: Animals; Ethylnitrosourea; Female; H-2 Antigens; Lung Neoplasms; Major Histocompatibility Complex; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Pregnancy | 1983 |
Influence of vitamin A on the formation of ethylnitrosourea (ENU)-induced leukemias.
Topics: Adenoma; Aging; Animals; Diterpenes; Ethylnitrosourea; Female; Leukemia, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Retinyl Esters; Vitamin A | 1983 |
Genetics of transplacentally induced teratogenic and carcinogenic effects in rabbits treated with N-nitroso-N-ethylurea.
Topics: Animals; Ethylnitrosourea; Female; Kidney Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Neurofibroma; Nitrosourea Compounds; Pregnancy; Rabbits; Sex Factors; Species Specificity | 1982 |
Effect of phenobarbital on the development of tumors in mice treated neonatally with N-ethyl-N-nitrosourea.
Topics: Animals; Ethylnitrosourea; Female; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimental; Nervous System Neoplasms; Phenobarbital | 1982 |
The effect of nerve growth factor and antibodies to nerve growth factor on ethylnitrosourea carcinogenesis in mice.
Topics: Animals; Ethylnitrosourea; Female; Immunoglobulin G; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nerve Growth Factors; Nervous System Neoplasms; Nitrosourea Compounds; Urogenital Neoplasms | 1980 |
Histogenesis of the papillary Clara cell adenoma.
Topics: Age Factors; Animals; Cystadenoma; Ethylnitrosourea; Female; Lung Neoplasms; Mice; Neoplasms, Experimental; Pregnancy | 1981 |
Metastasis from the brain of transplanted N-ethyl-N-nitrosourea-induced central nervous system tumors in rats.
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Glioma; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
Modifying role of partial hepatectomy and gonadectomy in ethylnitrosourea-induced hepatocarcinogenesis.
Topics: Animals; Castration; Ethylnitrosourea; Female; Harderian Gland; Hepatectomy; Kidney Neoplasms; Liver Neoplasms, Experimental; Liver Regeneration; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Ovarian Neoplasms; Sex Factors; Stomach Neoplasms | 1980 |
A scanning electron microscopic study of the Type II and Clara cell adenoma of the mouse lung.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Lung Neoplasms; Mice; Microscopy, Electron, Scanning; Neoplasms, Experimental; Pregnancy | 1980 |
Comparative two-stage cancer tests of ethylene oxide, N-(2-hydroxyethyl)-N-nitrosourea and X-rays.
Topics: Animals; Carcinogenicity Tests; Carcinogens; Ethylene Oxide; Ethylnitrosourea; Lung Neoplasms; Male; Mice; Neoplasms, Radiation-Induced; Skin Neoplasms; Tetradecanoylphorbol Acetate; X-Rays | 1994 |
Tissue distribution of polybutylcyanoacrylate nanoparticles loaded with spin-labelled nitrosourea in Lewis lung carcinoma-bearing mice.
Topics: Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Enbucrilate; Ethylnitrosourea; Injections, Intraperitoneal; Liver; Lung Neoplasms; Mice; Mice, Inbred C57BL; Microspheres; Particle Size; Spin Labels; Spleen; Tissue Distribution | 1994 |
A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H2 complex.
Topics: Animals; Chromosome Mapping; Ethylnitrosourea; Female; Genetic Predisposition to Disease; H-2 Antigens; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Pulmonary Alveoli; Recombination, Genetic | 1995 |
Vitamin D3 receptor expression in N-ethylnitrosourea-induced mouse pulmonary adenomas.
Topics: Adenoma; Animals; Binding Sites; Blotting, Northern; Blotting, Western; Bronchi; Ethylnitrosourea; Immunohistochemistry; In Situ Hybridization; Lung Neoplasms; Mice; Receptors, Calcitriol; RNA, Messenger | 1994 |
Oncogene activation: c-raf-1 gene mutations in experimental and naturally occurring tumors.
Topics: Animals; Butylated Hydroxytoluene; Crosses, Genetic; DNA Mutational Analysis; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Lung Neoplasms; Mice; Mice, Inbred AKR; Multigene Family; Mutation; Neoplasms; Neoplasms, Experimental; Oncogenes; Point Mutation; Proto-Oncogene Mas | 1993 |
Selective mutation of K-ras by N-ethylnitrosourea shifts from codon 12 to codon 61 during fetal mouse lung maturation.
Topics: Adenocarcinoma, Papillary; Adenoma; Animals; Carcinogens; Codon; Ethylnitrosourea; Gene Expression; Genes, ras; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mutagenesis; Mutagens; Proto-Oncogene Proteins c-raf; ras Proteins | 1998 |
Complexity of lung cancer modifiers: mapping of thirty genes and twenty-five interactions in half of the mouse genome.
Topics: Animals; Animals, Congenic; Carcinogens; Chromosome Mapping; Ethylnitrosourea; Female; Genes; Genetic Predisposition to Disease; Genome; Genotype; Immunity, Innate; Karyotyping; Lung Neoplasms; Mice; Mice, Inbred C57BL; Phenotype; Pregnancy | 2001 |
Morphology and metastatic nature of induced hepatic nodular lesions in C57BL x C3H F1 mice.
Topics: Animals; Benzidines; Benzopyrenes; Carcinoma, Hepatocellular; Diethylnitrosamine; Ethylnitrosourea; Female; Hyperplasia; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental | 1978 |
Tumors in two generations of mice in different environmental conditions.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Lactation; Leukemia, Experimental; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Pregnancy | 1977 |
Lung tumor-associated derepressed alloantigen coded for by the K region of the H-2 major histocompatibility complex.
Topics: Animals; Antigens, Neoplasm; Chromosome Mapping; Ethylnitrosourea; Female; Genes, MHC Class II; Genetic Linkage; H-2 Antigens; Lung Neoplasms; Male; Mice; Neoplasms, Experimental | 1978 |
Histologic and ultrastructural features of the clara cell adenoma of the mouse lung.
Topics: Adenoma; Animals; Cell Membrane; Cell Nucleus; Cytoplasm; Endoplasmic Reticulum; Ethylnitrosourea; Lung Neoplasms; Mice; Mitochondria; Pulmonary Alveoli | 1979 |
Tumor development in lung of ddY mice following transplacental exposure to 1-ethyl-1-nitrosourea.
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Gestational Age; Injections, Intraperitoneal; Injections, Intravenous; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Time Factors; Urethane | 1979 |
Induction of tumors by direct injection of N-ethyl-N-nitrosourea into the amniotic space of the mouse fetus.
Topics: Adenoma; Amnion; Animals; Drug Evaluation, Preclinical; Ethylnitrosourea; Female; Fetus; Gestational Age; Injections; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy | 1979 |
[Blastomogenesis in mice due to postnatal effect of N-nitrosoethylurea and x-ray irradiation].
Topics: Adenocarcinoma; Adenoma; Animals; Ethylnitrosourea; Female; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nitrosourea Compounds; Ovarian Neoplasms; X-Rays | 1977 |
[Effect of N-nitrosoethylurea dosage and postnatal x-ray irradiation on transplacental blastomogenesis in mice].
Topics: Adenoma; Animals; Ethylnitrosourea; Female; Fetus; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nitrosourea Compounds; Ovarian Neoplasms; Placenta; Pregnancy | 1977 |
Prenatal multicarcinogenesis by ethylnitrosourea in mice.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ethylnitrosourea; Female; Fetus; Gestational Age; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Ovarian Neoplasms; Peripheral Nervous System Neoplasms; Pregnancy; Sex Factors; Stomach Neoplasms | 1977 |
H-2a-associated alloantigen expressed by several transplacentally-induced lung tumours of C3Hf mice.
Topics: Animals; Ethylnitrosourea; Fetus; Histocompatibility Antigens; Immunity, Cellular; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplasms, Experimental | 1977 |
[Tumors in BALB C mice after transplacental exposure to N-nitrosoethylurea in progenesis].
Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Ethylnitrosourea; Female; Fetus; Leydig Cell Tumor; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Testicular Neoplasms | 1977 |
Common tumor-associated transplantation alloantigen detected on a proportion of lung tumors induced transplacentally in several strains of mice.
Topics: Animals; Antigens, Neoplasm; Cross Reactions; Ethylnitrosourea; Female; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Pregnancy | 1977 |
The multipotential carcinogenic action of N-ethyl-N-nitrosourea administered neonatally to mice.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Species Specificity | 1976 |
Derepressed alloantigen in transplacentally induced lung tumor coded for by H-2 linked gene.
Topics: Animals; Antigens, Neoplasm; Ethylnitrosourea; Genes; Genetic Linkage; Histocompatibility Antigens; Immunity; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; X-Rays | 1976 |
[Cytogenetic characteristics of lung tumors induced by exposing BALB/C mice to transplacental N-nitrosoethylurea].
Topics: Adenocarcinoma; Animals; Chromosomes; Ethylnitrosourea; Female; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrosourea Compounds; Ploidies; Pregnancy | 1976 |
Susceptibility of fetal lung to transplacental 1-ethyl-1-nitrosourea: its relation to epithelial proliferation.
Topics: Adenoma; Animals; Cell Division; Epithelial Cells; Ethylnitrosourea; Female; Gestational Age; Lung; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Nitrosourea Compounds; Pregnancy | 1976 |
Isolation of subclones with different tumorigenicity and metastatic ability from rat nephroblastoma cell line, ENUT.
Topics: Animals; Carcinogenicity Tests; Cell Division; Ethylnitrosourea; Immunohistochemistry; Kidney Neoplasms; Lung Neoplasms; Microscopy, Electron; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Wilms Tumor | 1992 |
Keratin expression in chemically induced mouse lung adenomas.
Topics: Adenoma; Animals; Benzopyrenes; Ethylnitrosourea; Immunohistochemistry; Keratins; Lung Neoplasms; Male; Mice; Mice, Inbred A; Microscopy, Electron | 1992 |
Mutagenesis of the K-ras protooncogene in mouse lung tumors induced by N-ethyl-N-nitrosourea or N-nitrosodiethylamine.
Topics: Animals; Diethylnitrosamine; Ethylnitrosourea; Female; Genes, ras; Lung Neoplasms; Male; Mice; Mutagenesis; Polymerase Chain Reaction; Proto-Oncogenes | 1992 |
Derivation of tumorigenic and non-tumorigenic mouse alveolar type-II cell lines from fetal type-II cells after a combined in vivo/in vitro carcinogen treatment.
Topics: Animals; Cell Division; Culture Media; Ethylnitrosourea; Female; Fetus; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Phospholipids; Pulmonary Alveoli; Tumor Cells, Cultured | 1992 |
Transplacental induction of mouse lung tumors: stage of fetal organogenesis in relation to frequency, morphology, size, and neoplastic progression of N-nitrosoethylurea-induced tumors.
Topics: Animals; Ethylnitrosourea; Female; Fetal Diseases; Gestational Age; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Pregnancy | 1991 |
Clara cell adenomas of the mouse lung. Interaction with alveolar type 2 cells.
Topics: Adenoma; Age Factors; Animals; Autoradiography; Bronchi; Cytoplasmic Granules; Ethylnitrosourea; Female; Histocytochemistry; Inclusion Bodies; Lung Neoplasms; Mice; Microscopy, Electron; Pregnancy; Pulmonary Alveoli; Staining and Labeling | 1985 |
Quantitative analysis of alveolar type II cell tumors in mice by whole lung serial and step sections.
Topics: Animals; Ethylnitrosourea; Female; Lung; Lung Neoplasms; Mice; Mice, Inbred C3H; Pregnancy; Staining and Labeling | 1989 |
Nucleoside analogues: 8. Some isomers of B.3839, the original 5-fluorouracil/nitrosourea molecular combination, and their effect on colon, breast and lung tumours in mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Screening Assays, Antitumor; Ethylnitrosourea; Fluorouracil; Isomerism; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Nitrosourea Compounds | 1989 |
Glucocorticoid hormone effect on transplacental carcinogenesis and lung differentiation: influence of histocompatibility-2 complex.
Topics: Adenocarcinoma, Papillary; Animals; Embryonic and Fetal Development; Ethylnitrosourea; Female; Glucocorticoids; H-2 Antigens; Haplotypes; Intestinal Neoplasms; Intestine, Small; Lung; Lung Neoplasms; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Pulmonary Surfactants | 1989 |
Influence of mouse major histocompatibility complex (H-2) on N-ethyl-N-nitrosourea-induced tumor formation in various organs.
Topics: Animals; Ethylnitrosourea; Female; H-2 Antigens; Intestinal Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Sex Factors; Species Specificity | 1988 |
Mouse papillary lung tumors transplacentally induced by N-nitrosoethylurea: evidence for alveolar type II cell origin by comparative light microscopic, ultrastructural, and immunohistochemical studies.
Topics: Age Factors; Animals; Antigens; Carcinoma, Papillary; Ethylnitrosourea; Female; Fetus; Immunohistochemistry; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Microscopy, Fluorescence; Nitroblue Tetrazolium; Pregnancy; Pulmonary Surfactants; Rabbits | 1988 |
Effect of gestational development of lung tumor size and morphology in the mouse.
Topics: Animals; Body Weight; Ethylnitrosourea; Female; Fetus; Gestational Age; Lung; Lung Neoplasms; Male; Mice; Pregnancy | 1988 |
Synergistic induction of tumours in NMRI mice by combined foetal X-irradiation with low doses and ethylnitrosourea administered to juvenile offspring.
Topics: Animals; Cocarcinogenesis; Ethylnitrosourea; Female; Fetus; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental | 1988 |
Ethylnitrosourea-induced transplacental carcinogenesis in the mouse: tumor response, DNA binding, and adduct formation.
Topics: Adenoma; Animals; DNA; DNA Damage; Ethylnitrosourea; Female; Gestational Age; Liver Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Pregnancy; Tissue Distribution | 1987 |
Effect of subsequent treatment of chloroform or phenobarbital on the incidence of liver and lung tumors initiated by ethylnitrosourea in 15 day old mice.
Topics: Animals; Chloroform; Cocarcinogenesis; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Nitrosourea Compounds; Phenobarbital; Sex Factors | 1985 |