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ethylnitrosourea and Leukemia L 1210

ethylnitrosourea has been researched along with Leukemia L 1210 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's4 (36.36)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Joshua, AV; Lown, JW; McLaughlin, LW1
Dolan, ME; Weinkam, RJ1
Erickson, LC; Gibson, NW; Hickman, JA1
Gwilt, PR; Lawson, T1
Bodell, WJ; Chen, FX; Church, KM; Gold, B; Zhang, Y1
Erickson, LC; Kurpad, C; Maze, R; Pegg, AE; Williams, DA1
Fox, P; Green, D; Nagourney, R; Panasci, LC; Schein, PS1
Kann, HE1
Brundrett, RB; Colvin, M; Cowens, W; Jardine, I; Ludlum, DB1
Filippeschi, S; Spinelli, L; Ubezio, P1
Ducore, JM; Rosenstein, BS1

Other Studies

11 other study(ies) available for ethylnitrosourea and Leukemia L 1210

ArticleYear
Noval antitumor nitrosoureas and related compounds and their reactions with DNA.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:7

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cross-Linking Reagents; DNA; Leukemia L1210; Mice; Nitrosourea Compounds; Structure-Activity Relationship

1980
An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Drug Evaluation, Preclinical; Ethylnitrosourea; Leukemia L1210; Leukemia P388; Lomustine; Mice; Nitrosourea Compounds; Streptozocin; Structure-Activity Relationship

1983
Effects of the antitumor agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one on the DNA of mouse L1210 cells.
    Cancer research, 1984, Volume: 44, Issue:5

    Topics: Animals; Cell Division; Dacarbazine; DNA, Neoplasm; Ethylnitrosourea; Imidazoles; Kinetics; Leukemia L1210; Mice; Neoplasm Proteins; Nitrogen Mustard Compounds; Protein Binding

1984
Clofibrate enhances the DNA damaging action and cytotoxicity of nitrosoureas.
    Cancer letters, 1993, Jun-15, Volume: 70, Issue:1-2

    Topics: Animals; Carmustine; Cell Survival; Clofibrate; DNA Damage; DNA, Neoplasm; Drug Synergism; Ethylnitrosourea; Leukemia L1210; Mice

1993
DNA crosslinking, sister chromatid exchange and cytotoxicity of N-2-chloroethylnitrosoureas tethered to minor groove binding peptides.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: Alkylation; Animals; Base Sequence; Carcinogens; Carmustine; Cell Survival; Dipeptides; DNA; Ethylnitrosourea; Kinetics; Leukemia L1210; Mice; Molecular Sequence Data; Plasmids; Sister Chromatid Exchange; Time Factors; Tumor Cells, Cultured

1993
Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma; Ethylnitrosourea; Female; Genetic Vectors; Guanine; Hematopoietic Stem Cells; Humans; Leukemia L1210; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Retroviridae; Tumor Cells, Cultured

1999
A structure-activity analysis of chemical and biological parameters of chloroethylnitrosoureas in mice.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 1

    Topics: Alkylation; Animals; Bone Marrow; Carmustine; Ethyl Chloride; Ethylnitrosourea; Half-Life; Leukemia L1210; Leukocyte Count; Lomustine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neutrophils; Nitrosourea Compounds; Statistics as Topic; Streptozocin; Structure-Activity Relationship

1977
Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; Ethylnitrosourea; Leukemia L1210; Lomustine; Neoplasm Proteins; Nitrosourea Compounds; RNA, Neoplasm; Streptozocin; Time Factors

1978
A chemical basis for the antitumor activity of chloroethylnitrosoureas.
    Biochemical pharmacology, 1976, Mar-15, Volume: 25, Issue:6

    Topics: Animals; Antineoplastic Agents; Buffers; Carmustine; Chemical Phenomena; Chemistry; Ethylnitrosourea; Ions; Leukemia L1210; Lomustine; Nitrosourea Compounds; Solutions; Time Factors

1976
Method for kinetic analysis of drug-induced cell cycle perturbations.
    Cytometry, 1991, Volume: 12, Issue:2

    Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Cycle; DNA; Ethylnitrosourea; Flow Cytometry; Kinetics; Leukemia L1210; Mice; Staining and Labeling; Tumor Cells, Cultured

1991
Theophylline release of replicon initiation inhibition by nitrosoureas correlates with the synergistic killing in L1210 leukemia in vitro.
    Mutation research, 1985, Volume: 146, Issue:1

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; DNA, Neoplasm; Drug Synergism; Ethylnitrosourea; Leukemia L1210; Mice; Replicon; Theophylline

1985