ethylnitrosourea has been researched along with Glioma in 168 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 100 (59.52) | 18.7374 |
| 1990's | 27 (16.07) | 18.2507 |
| 2000's | 20 (11.90) | 29.6817 |
| 2010's | 18 (10.71) | 24.3611 |
| 2020's | 3 (1.79) | 2.80 |
| Authors | Studies |
|---|---|
| Ito, R; Morikawa, S; Murata, K; Takaki, K; Yamamoto, A | 1 |
| Carrera-González, MP; Martínez-Martos, JM; Ramírez-Expósito, MJ | 1 |
| Carrera-González, MP; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ | 1 |
| Bhattacharya, D; Chaudhuri, S; Datta, A; Faruk Sk Md, O; Ghosh, TK; Hazra, I; Mondal, S; Ronsard, L; Singh, MK | 1 |
| Chang, C; Hsu, YH; Jang, T; Lin, CY; Lin, MH; Recht, L; Siow, TY; Tung, YY | 1 |
| Cartron, PF; Debien, E; Hervouet, E; Menanteau, J; Olivier, C; Pouliquen, D; Staehlin, O; Vallette, FM | 1 |
| Fan, T; Li, S; Sun, G; Zhao, L; Zhong, R | 1 |
| Acharya, S; Basu, AK; Bhattacharjee, P; Bhattacharya, D; Chatterjee, S; Chaudhuri, S; Das, T; Ghosh, TK; Kumar, P; Sa, G; Singh, MK | 1 |
| Cohen, HJ; Deng, X; Fu, C; Guo, M; Hao, S; Jang, T; Li, Z; Ling, XB; Liu, R; Merchant, M; Recht, L; Tan, Z; Whitin, JC; Zheng, L | 1 |
| Doi, Y; Kanagawa, M; Matsumoto, H; Maya, Y; Nakata, N; Oka, S; Shirakami, Y; Tanaka, A; Toyama, M | 1 |
| Bulnes, S; Carrasco, A; García-Blanco, A; Lafuente, JV; Pomposo, I | 1 |
| Huang, YC; Lee, WH; Liu, SC; Liu, SJ; Su, CH; Tseng, YY; Wang, YC; Yang, ST | 1 |
| Irvin, DM; McNeill, RS; Miller, CR | 1 |
| Brors, B; Diessl, N; Hutter, B; Kindler-Röhrborn, A; Kleihues, P; Koelsch, B; Liu, HK; Oh, JE; Ohgaki, H; Satomi, K; Wang, Q; Wiestler, O; Wolf, S | 1 |
| Bodell, WJ | 3 |
| Babu, PP; Challa, S; Panigrahi, M; Sareddy, GR | 1 |
| Bilbao, J; Bulnes, S; Lafuente, JV | 1 |
| Argandoña, EG; Bengoetxea, H; Bulnes, S; Lafuente, JV; Leis, O; Ortuzar, N | 1 |
| Acharya, S; Bhattacharjee, M; Chatterjee, S; Chaudhuri, S; Kumar, P | 1 |
| Doblas, S; Garteiser, P; He, T; Herlea, O; Lupu, F; Saunders, D; Silasi-Mansat, R; Smith, N; Towner, RA; Watanabe, Y | 1 |
| Barth, RF; Chou, TC; Elleaume, H; Grecula, JC; Gupta, N; Hoff, BA; Huo, T; Ross, BD; Rousseau, J; Weldon, M; Yang, W | 1 |
| Calaoagan, JM; Jang, T; Kwon, E; Laderoute, KR; Recht, L; Samuelsson, S | 1 |
| Binh, NH; Hara, A; Hatano, Y; Hirata, A; Kobayashi, K; Kuno, T; Satoh, K; Takamatsu, M; Tomita, H | 1 |
| Cohen, HJ; Jang, T; Lau, K; Merchant, M; Recht, B; Recht, L; Whitin, JC; Yu, TT | 1 |
| Bjerkvig, R; Enger, PO; Ersland, L; Huszthy, PC; Lund-Johansen, M; Lundervold, A; Nordli, H; Standnes, T; Thorsen, F | 1 |
| Zhang, YF; Zhang, ZY | 1 |
| Begum, Z; Chaudhuri, S; Ghosh, A; Mazumdar, M; Mukherjee, J; Sarkar, P; Sarkar, S | 1 |
| Chaudhuri, S; Ghosh, A; Mukherjee, J; Sarkar, S | 1 |
| Chaudhuri, S; Ghosh, A; Mukherjee, J | 1 |
| Duong, T; Jang, T; Kim, S; Lapointe, D; Litofsky, NS; Low, HP; Recht, L; Ross, AH; Savarese, T; Vogel, H; Weimann, JM | 1 |
| Babu, PP; Bhaskara, VK; Sundaram, C | 1 |
| Bulnes, S; Lafuente, JV | 1 |
| Chang, C; Hsu, YH; Jang, T; Merchant, M; Recht, B; Recht, L; Sathy, B | 1 |
| Debien, E; Gratas, C; Hervouet, E; Homma, T; Le Cabellec, MT; Meflah, K; Menanteau, J; Olivier, C; Pedelaborde, F; Pouliquen, D; Vallette, FM | 1 |
| Blasberg, RG; Groothuis, DR; Molnar, P | 1 |
| Chang, MJ; Koestner, A; Palayoor, T; Schumm, DE; Webb, TE | 1 |
| Arita, N; Hayakawa, T; Horibata, K; Mogami, H; Morimoto, K; Ushio, Y; Yoshimine, T | 2 |
| Tramontano, D; Vescia, S | 1 |
| Perez-Polo, JR; Vinores, SA | 2 |
| Lantos, PL | 3 |
| Knowles, JF | 1 |
| Enke, H; Rath, FW | 1 |
| Iablonovskaia, LIa; Khalanskiĭ, AS; Kondakova, LI; Morozov, IuE | 1 |
| Blasberg, RG; Fenstermacher, JD; Groothuis, D; Horowitz, M; Kobayashi, T; Molnar, P; Rice, JM | 2 |
| Bertolotto, A; Giordana, MT; Magrassi, ML; Mauro, A; Migheli, A; Schiffer, D | 1 |
| Bonnin, JM; Marangos, PJ; Rubinstein, LJ; Vinores, SA | 1 |
| Abe, M; Kitamura, K; Nishio, S; Ohta, M | 1 |
| Ikeda, T; Kohno, S; Maeda, H; Matsuo, T; Tashiro, T | 1 |
| Giordana, MT; Mauro, A; Schiffer, D | 1 |
| De Bernardo, E | 1 |
| Arita, N; Hayakawa, T; Horibata, K; Mori, T; Ushio, Y; Yoshimine, T | 1 |
| Ilsen, HW; Mennel, HD; Petrovici, IN; Szymas, J; Zülch, KJ | 1 |
| Hayakawa, T; Kato, A; Mogami, H; Ushio, Y; Yamada, K; Yamada, N | 2 |
| Arita, N; Hayakawa, T; Kato, A; Mogami, H; Ushio, Y; Yamada, K | 2 |
| Bressler, JP; Cole, R; de Vellis, J | 1 |
| Maat, B; van Bekkum, DW; van Zwieten, MJ; Vecht, CJ | 1 |
| Cohadon, F | 1 |
| Yun, K | 1 |
| Berger, MS; Blank, A; Bobola, MS; Silber, JR | 1 |
| Aas, AT; Blennow, C; Brun, A; Salford, LG; Strömblad, S | 1 |
| Handa, J; Matsumura, K; Nakasu, S; Nioka, H | 1 |
| Arita, N; Hayakawa, T; Higuchi, M; Hiraga, S; Izumoto, S; Ohnishi, T; Taki, T; Yamamoto, H | 1 |
| Kanamatsu, T; Tsukada, Y | 1 |
| Broglia, E; Perin, A; Sessa, A; Terreni, MR | 2 |
| Higami, Y; Ikeda, T; Ikeno, Y; Shimokawa, I | 1 |
| Blass-Kampmann, S; Deissler, H; Kindler-Röhrborn, A; Meyer, HE; Rajewsky, MF | 1 |
| Higami, Y; Ikeda, T; Okimoto, T; Shimokawa, I | 1 |
| Bederson, JB; Germano, IM; Segal, DH | 1 |
| Hiasa, Y; Konishi, N; Nakamura, M; Sakaki, T; Tsunoda, S; Tsuzuki, T; Yabuno, T | 1 |
| Darcel, F; Jallet, P; Le Jeune, JJ; Pouliquen, D; Rousseau, V | 1 |
| Blaivas, M; Kish, P; Muraszko, KM; Ross, DA; Strawderman, M | 1 |
| Bartels, HJ; Kappler, R; Kraus, A; Kühne, C; Mennel, HD; Piontek, G; Schlegel, J | 1 |
| Boncinelli, E; Canal, N; Feltri, ML; Nemni, R; Pardini, CL; Previtali, SC; Quattrini, A; Wrabetz, L | 1 |
| Calloni, A; Perin, A; Rabellotti, E; Sessa, A; Tunici, P | 1 |
| Buslei, R; Kindler-Röhrborn, A; Koelsch, BU; Rajewsky, MF; Wiestler, OD; Zabel, S | 1 |
| Désy, M; Devaux, C; Franco, E; Gaboury, L; Mandeville, R; Mercier, G; Paris-Nadon, L; Rocheleau, N; Sidrac-Ghali, S | 1 |
| Hara, A; Mori, H; Sakai, N; Shinoda, J; Takenaka, K; Yano, H; Yoshimi, N | 1 |
| Simmens, SJ; Zook, BC | 1 |
| Arrieta, O; Guevara, P; Palencia, G; Reyes, S; Rivera, E; Sotelo, J | 1 |
| Blaivas, M; Kish, PE; McMahon, G; Muraszko, KM; Ross, BD; Ross, DA; Strawderman, M | 1 |
| D'Sa, C; Klocke, BJ; Leonard, JR; Roth, KA | 1 |
| Carnaud, C; Cornain, S; Klein, E; Rajewsky, MF; Silverman, D | 1 |
| Matsumoto, S; Tanaka, M | 1 |
| Coates, PW; Spence, AM | 1 |
| Giordana, MT; Paoletti, P; Pezzotta, S; Schiffer, D | 1 |
| Cox, DJ; Lantos, PL; Pilkington, GJ | 1 |
| Thust, R | 1 |
| Dahme, E; Schröder, B; Stavrou, D | 1 |
| Pfeiffer, SE; Ramadan, MA; Wechsler, W | 1 |
| Claisse, PJ; Lantos, PL; Roscoe, JP | 2 |
| Cravioto, H; Yoshida, J | 1 |
| Das, GD; Pfaffenroth, MJ | 1 |
| Hayakawa, T; Mogami, H; Mori, T; Morimoto, K; Ushio, Y; Yoshimine, T | 1 |
| Lantos, PL; Pilkington, GJ | 3 |
| Hellström, I; Hellström, KE; Spence, AM; Sullivan, K; Van Belle, G; Wahlström, T | 1 |
| Spence, AM | 1 |
| Bruno, F; Giordana, MT; Paoletti, P; Pezzotta, S; Racagni, G; Schiffer, D | 1 |
| Matsumoto, M | 1 |
| Au, W; Mandybur, TI; Soukup, SW | 1 |
| Kageyama, N; Kameyama, Y; Kobayashi, T; Umemura, S; Yoshida, J | 1 |
| Giordana, MT; Lechner, C; Paoletti, P; Pezzotta, S; Schiffer, D | 1 |
| Hince, TA; Roscoe, JP | 1 |
| Allen, N; Coleman, MT | 1 |
| Gerlach, H; Peschel, B; Rath, FW; Schreiber, D; Wessel, H | 1 |
| Haugen, A; Laerum, OD | 1 |
| Fujiwara, K; Matsumoto, S; Tamaki, N; Taomoto, K | 1 |
| Conley, FK | 1 |
| Bosch, DA | 1 |
| Groneck, P; Mennel, HD | 1 |
| Claisse, PJ; Roscoe, JP | 1 |
| Cox, DJ; Lantos, PL | 1 |
| Taomoto, K | 1 |
| Abe, H; Ito, T; Kobayashi, N; Tashiro, K; Tsuru, M | 1 |
| Norrell, H; Slagel, DE | 1 |
| Kalter, H; Mandybur, TI; Warkany, J | 1 |
| Lantos, PL; Roscoe, JP; Skidmore, CJ | 1 |
| Braun, M; Grasso, A; Wechsler, W | 1 |
| Tokuda, K | 1 |
| Giordana, MT; Migheli, A; Mocellini, C; Schiffer, D; Villare, F | 1 |
| Ikeda, T; Iwasaki, K; Matsuo, T; Shimokawa, I; Takeshima, F | 1 |
| Koestner, A; Lovell, K; Okazaki, DL; Raju, NR; Yaeger, MJ | 1 |
| Bigner, DD; Bigner, SH; Brent, TP; Mitra, S; Ostrowski, LE; Rasheed, A; Schold, SC; von Wronski, MA | 1 |
| Bodell, WJ; Ludlum, DB; Matijasevic, Z | 1 |
| Anderer, U; Dertinger, H; Knedlitschek, G; Weibezahn, KF | 1 |
| Huang, Y; Tao, H; Yang, G | 1 |
| Bilzer, T; Reifenberger, G; Seitz, RJ; Wechsler, W | 1 |
| Fukushima, M; Jinnouchi, T; Mori, K; Shibata, S | 1 |
| Abe, S; Hinokuma, K; Kumanishi, T; Nishiyama, A; Yamada, M; Yoshida, Y | 1 |
| Neame, SJ; Roscoe, JP | 1 |
| Swenberg, JA; Walker, VE | 1 |
| Palencia, G; Perez, R; Rosas, N; Sotelo, J | 1 |
| Ikeda, T; Iwasaki, K; Mashimoto, H; Matsuo, T; Shimokawa, I | 1 |
| Lantos, PL; Martin, JM; Pilkington, GJ | 1 |
| Kriegel, H; Schmahl, W | 1 |
| Greenwood, J; Lantos, PL; Luthert, PJ; Pratt, OE | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N | 1 |
| Blasberg, RG; Groothuis, DR; Warnke, PC | 1 |
| Dingeldein, E; Jansen, J; Mandel, T; Mennel, HD; Rama, B | 1 |
| Abe, M; Amano, K; Hatanaka, H; Kitamura, K; Ohta, M; Tateishi, J | 1 |
| Fukui, M; Inoue, T; Iwaki, T; Nishio, S; Takeshita, I; Tashima, T | 1 |
| Bodell, WJ; Ludlum, DB; Tokuda, K | 1 |
| Hayakawa, T; Maruno, M; Mogami, H; Nakajima, Y; Ushio, Y; Yoshimine, T | 1 |
| Hasgekar, NN; Lalitha, VS; Pendse, AM | 1 |
| Altena, B; Lens, PF; Nusse, R | 1 |
| Kroh, H | 1 |
| Aoyama, H; Fujioka, Y; Ito, A; Naito, M; Naito, Y | 1 |
| Aoyama, H; Ito, A; Naito, M | 1 |
| Aoyama, H; Fujioka, Y; Ito, A; Naito, M | 1 |
| Lin, JK; Lin, LI | 1 |
| Yoshino, T | 1 |
| Motoi, M; Ogawa, K; Yoshino, T | 1 |
| Holzgraefe, M; Mennel, HD; Rama, B; Spoerri, O | 1 |
| Koestner, A | 1 |
| Bitoh, S; Hayakawa, T; Jamshid, J; Maruno, M; Mogami, H; Ushio, Y; Yoshimine, T | 1 |
| Abe, H; Allen, N; Clendenon, NR; Swenberg, JA | 1 |
1 review(s) available for ethylnitrosourea and Glioma
| Article | Year |
|---|---|
Nerve growth factor and neural oncology.
Topics: Animals; Cell Differentiation; Cells, Cultured; DNA; Ethylnitrosourea; Female; Ganglia; Gestational Age; Glioma; Humans; Neoplasms, Nerve Tissue; Nerve Growth Factors; Nervous System Neoplasms; Neuroblastoma; Neuroglia; Neurons; Pheochromocytoma; Pregnancy; Prenatal Exposure Delayed Effects | 1983 |
167 other study(ies) available for ethylnitrosourea and Glioma
| Article | Year |
|---|---|
Histologic Distribution and Characteristics on MR Imaging of Ultrasmall Superparamagnetic Iron Oxide in Ethyl-nitrosourea-induced Endogenous Rat Glioma.
Topics: Animals; Contrast Media; Dextrans; Ethylnitrosourea; Ferrosoferric Oxide; Glioma; Magnetic Resonance Imaging; Magnetite Nanoparticles; Oxides; Rats | 2021 |
Sex differences exist in brain renin-angiotensin system-regulating aminopeptidase activities in transplacental ethyl-nitrosourea-induced gliomas.
Topics: Aminopeptidases; Animals; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Male; Rats, Wistar; Renin-Angiotensin System; Sex Characteristics | 2021 |
Gender differences in the antioxidant response of oral administration of hydroxytyrosol and oleuropein against N-ethyl-N-nitrosourea (ENU)-induced glioma.
Topics: Administration, Oral; Animals; Antioxidants; Ethylnitrosourea; Glioma; Iridoid Glucosides; Phenylethyl Alcohol; Rats; Sex Characteristics | 2021 |
T11TS immunotherapy repairs PI3K-AKT signaling in T-cells: Clues toward enhanced T-cell survival in rat glioma model.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Brain Neoplasms; CD28 Antigens; CD58 Antigens; Cell Survival; Ethylnitrosourea; Female; Glioma; Immunotherapy; Male; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Signal Transduction; T-Lymphocytes; Tumor Escape | 2018 |
Visualization of rodent brain tumor angiogenesis and effects of antiangiogenic treatment using 3D ΔR2-μMRA.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Corpus Striatum; Ethylnitrosourea; Female; Glioma; Imaging, Three-Dimensional; Immunoenzyme Techniques; Magnetic Resonance Angiography; Neoplasm Transplantation; Neovascularization, Pathologic; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2013 |
Antioxidants delay clinical signs and systemic effects of ENU induced brain tumors in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Brain Neoplasms; Cell Proliferation; Ethylnitrosourea; Female; Glioma; Insulin-Like Growth Factor Binding Protein 5; Ki-67 Antigen; Male; Rats; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Sodium Selenite; Superoxide Dismutase; Zinc | 2013 |
Investigations on the effect of O(6)-benzylguanine on the formation of dG-dC interstrand cross-links induced by chloroethylnitrosoureas in human glioma cells using stable isotope dilution high-performance liquid chromatography electrospray ionization tand
Topics: Alkylating Agents; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyguanosine; DNA; DNA Damage; Ethylnitrosourea; Glioma; Guanine; Humans; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |
The novel immunotherapeutic molecule T11TS modulates glioma-induced changes of key components of the immunological synapse in favor of T cell activation and glioma abrogation.
Topics: Animals; Apoptosis; Brain Neoplasms; CD2 Antigens; CD58 Antigens; Ethylnitrosourea; Female; Flow Cytometry; Fluorescent Antibody Technique; Glioma; Glycopeptides; Immunological Synapses; Lymphocyte Activation; Male; Mice; Mutagens; Signal Transduction; T-Lymphocytes | 2014 |
Cerebrospinal fluid protein dynamic driver network: At the crossroads of brain tumorigenesis.
Topics: Animals; Brain; Brain Neoplasms; Carcinogenesis; Cerebrospinal Fluid Proteins; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Glioma; Humans; Neoplasms, Experimental; Proteome; Rats | 2015 |
Evaluation of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid accumulation in low-grade glioma in chemically induced rat models: PET and autoradiography compared with morphological images and histopathological findings.
Topics: Alkylating Agents; Animals; Autoradiography; Blood-Brain Barrier; Brain Neoplasms; Carboxylic Acids; Cyclobutanes; Ethylnitrosourea; Female; Fluorine Radioisotopes; Glioma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Neoplasm Grading; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tissue Distribution | 2015 |
Nestin+cells forming spheroids aggregates resembling tumorspheres in experimental ENU-induced gliomas.
Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Glioma; Immunohistochemistry; Neoplastic Stem Cells; Nestin; Rats; Rats, Sprague-Dawley | 2016 |
Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drug-loaded nanofibrous membranes.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bibenzyls; Brain; Brain Neoplasms; Camptothecin; Cisplatin; Disease Models, Animal; Drug Delivery Systems; Ethylnitrosourea; Glioblastoma; Glioma; Humans; Irinotecan; Lactic Acid; Male; Nanofibers; Neurosurgical Procedures; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Tumor Burden | 2016 |
BRAF Mutations Open Doors for N-Ethyl-N-Nitrosourea-Induced Gliomagenesis.
Topics: Ethylnitrosourea; Glioma; Hearing Loss, Sensorineural; Humans; Mutation | 2016 |
Braf Mutations Initiate the Development of Rat Gliomas Induced by Postnatal Exposure to N-Ethyl-N-Nitrosourea.
Topics: Amino Acid Substitution; Animals; Ethylnitrosourea; Genotype; Glioma; Mutagenesis; Neurilemmoma; Point Mutation; Proto-Oncogene Proteins B-raf; Rats; Sequence Analysis, DNA | 2016 |
DNA alkylation products formed by 1-(2-chloroethyl)-1-nitrosourea as molecular dosimeters of therapeutic response.
Topics: Alkylation; Antineoplastic Agents, Alkylating; Carmustine; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; DNA Adducts; DNA Modification Methylases; DNA Repair Enzymes; Ethylnitrosourea; Glioma; Humans; Statistics as Topic; Tumor Suppressor Proteins | 2009 |
Wnt/beta-catenin/Tcf signaling pathway activation in malignant progression of rat gliomas induced by transplacental N-ethyl-N-nitrosourea exposure.
Topics: Animals; beta Catenin; DNA-Binding Proteins; Ethylnitrosourea; Female; Glioma; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins c-myc; Rats; Signal Transduction; Transcription Factor 4; Transcription Factors; Wnt Proteins | 2009 |
Microvascular adaptive changes in experimental endogenous brain gliomas.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Carcinogens; Ethylnitrosourea; Glioma; Immunohistochemistry; Microvessels; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley | 2009 |
The role of eNOS in vascular permeability in ENU-induced gliomas.
Topics: Animals; Autoantigens; Brain Neoplasms; Capillary Permeability; Disease Models, Animal; Ethylnitrosourea; Gadolinium; Glioma; Glucose Transporter Type 1; Nitric Oxide Synthase Type III; Pentetic Acid; Plant Lectins; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2010 |
Induction of G1 arrest in glioma cells by T11TS is associated with upregulation of Cip1/Kip1 and concurrent downregulation of cyclin D (1 and 3).
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Brain Neoplasms; Cyclin D; Cyclin D1; Cyclin D3; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Erythrocyte Membrane; Ethylnitrosourea; Female; Flow Cytometry; G1 Phase; Glioma; Glycoproteins; Male; Rats; Rats, Inbred Strains; Sheep; Tumor Cells, Cultured; Up-Regulation | 2010 |
In vivo detection of inducible nitric oxide synthase in rodent gliomas.
Topics: Albumins; Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Ethylnitrosourea; Female; Fluorescence; Gadolinium DTPA; Glioma; Immunohistochemistry; Male; Microscopy, Electron, Transmission; Molecular Probe Techniques; Neoplasm Transplantation; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Inbred F344 | 2010 |
Convection enhanced delivery of carboplatin in combination with radiotherapy for the treatment of brain tumors.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Combined Modality Therapy; Convection; Disease Models, Animal; Drug Delivery Systems; Ethylnitrosourea; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Radiation Dosage; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution; X-Ray Therapy | 2011 |
5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Blotting, Western; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Fluorescent Antibody Technique; Glioma; Immunohistochemistry; Neoplasm Staging; Phosphorylation; Rats; Rats, Sprague-Dawley | 2011 |
Galectin-3 in preneoplastic lesions of glioma.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Calcium-Binding Proteins; Cell Proliferation; Ethylnitrosourea; Female; Galectin 3; Glial Fibrillary Acidic Protein; Glioma; Humans; Microfilament Proteins; Precancerous Conditions; Rats; Rats, Wistar | 2013 |
Alterations in cerebrospinal fluid proteins in a presymptomatic primary glioma model.
Topics: Animals; Biomarkers; Brain; Brain Neoplasms; Cerebrospinal Fluid Proteins; Disease Models, Animal; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Glioma; Glutathione; Intermediate Filament Proteins; Nerve Tissue Proteins; Nestin; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Repair of DNA alkylation products formed in 9L cell lines treated with 1-(2-chloroethyl)-1-nitrosourea.
Topics: Alkylation; Animals; Cell Line; Cell Survival; DNA; DNA Repair; Ethylnitrosourea; Glioma; Rats; Tumor Cells, Cultured | 2003 |
Imaging of experimental rat gliomas using a clinical MR scanner.
Topics: Animals; Brain Neoplasms; Collagen; Disease Models, Animal; Endostatins; Ethylnitrosourea; Female; Glioma; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neoplasms, Experimental; Peptide Fragments; Rats; Transfection; Tumor Cells, Cultured | 2003 |
[p16 protein expression in the transplacental induced brain tumor in rat].
Topics: Animals; Brain; Brain Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Male; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Documentation of immune profile of microglia through cell surface marker study in glioma model primed by a novel cell surface glycopeptide T11TS/SLFA-3.
Topics: Alkylating Agents; Animals; Biomarkers; Brain; Brain Neoplasms; CD2 Antigens; CD4 Antigens; Cell Membrane; Cell Proliferation; Cell Separation; Erythrocytes; Ethylnitrosourea; Flow Cytometry; Glioma; Glycopeptides; Immunophenotyping; Ligands; Microglia; Microscopy, Electron, Scanning; Protein Binding; Rats; Receptors, Interleukin-2; Rosette Formation; Sheep | 2004 |
CD2-SLFA3/T11TS interaction facilitates immune activation and glioma regression by apoptosis.
Topics: Animals; Apoptosis; Brain Neoplasms; CD2 Antigens; CD58 Antigens; Erythrocytes; Ethylnitrosourea; Female; Flow Cytometry; Genes, MHC Class I; Glioma; Lymphocytes; Macrophages; Male; Microglia; Mutagens; Phosphatidylserines; Protein Binding; Rats; Receptors, Antigen, T-Cell; Rosette Formation; Sheep | 2004 |
ENU administration causes genomic instability along with single nucleotide polymorphisms in p53 during gliomagenesis: T11TS administration demonstrated in vivo apoptosis of these genetically altered tumor cells.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; CD58 Antigens; DNA Mutational Analysis; Ethylnitrosourea; Exons; Flow Cytometry; Genomic Instability; Glioma; Microsatellite Repeats; Mutagenesis; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Rats; Rats, Inbred Strains; Tumor Suppressor Protein p53 | 2006 |
Osteopontin expression in intratumoral astrocytes marks tumor progression in gliomas induced by prenatal exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Astrocytes; Biomarkers, Tumor; Cerebral Cortex; Disease Models, Animal; Disease Progression; Ethylnitrosourea; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Immunohistochemistry; Intermediate Filament Proteins; Nerve Tissue Proteins; Nestin; Osteopontin; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Sialoglycoproteins; Time Factors; Transfection | 2006 |
pERK, pAkt and pBad: a possible role in cell proliferation and sustained cellular survival during tumorigenesis and tumor progression in ENU induced transplacental glioma rat model.
Topics: Alkylating Agents; Animals; bcl-Associated Death Protein; Brain; Cell Proliferation; Cell Survival; Disease Models, Animal; Enzyme Activation; Ethylnitrosourea; Extracellular Signal-Regulated MAP Kinases; Female; Glioma; Male; Phosphorylation; Placenta; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction | 2006 |
VEGF immunopositivity related to malignancy degree, proliferative activity and angiogenesis in ENU-induced gliomas.
Topics: Alkylating Agents; Animals; Cell Proliferation; Ethylnitrosourea; Female; Fetus; Glioma; Humans; Neoplasm Staging; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2007 |
A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Disease Models, Animal; Disease Progression; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Intermediate Filament Proteins; Magnetic Resonance Imaging; Male; Nerve Tissue Proteins; Nestin; Osteopontin; Phenotype; Rats; Rats, Sprague-Dawley | 2008 |
Dietary prevention of malignant glioma aggressiveness, implications in oxidant stress and apoptosis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Ethylnitrosourea; Female; Fruit; Glioma; Immunohistochemistry; Male; Mitochondria, Liver; Oxidative Stress; Polymerase Chain Reaction; Pregnancy; Rats; RNA, Neoplasm; Vegetables | 2008 |
Regional blood flow and blood-to-tissue transport in five brain tumor models. Implications for chemotherapy.
Topics: Aminoisobutyric Acids; Animals; Astrocytoma; Biological Transport; Brain Neoplasms; Capillary Permeability; Carcinoma 256, Walker; Disease Models, Animal; Ethylnitrosourea; Glioma; Oligodendroglioma; Rats; Regional Blood Flow; Sarcoma, Avian | 1984 |
Characteristics of RNA release from rat brain nuclei and effect of neurocarcinogenesis.
Topics: Animals; Brain; Cell Nucleus; Ethylnitrosourea; Female; Glioma; Kinetics; Male; Neoplasms, Experimental; Poly A; Polyribosomes; Rats; RNA; RNA, Messenger; RNA, Ribosomal; Sex Factors | 1980 |
Distribution of bleomycin in ethylnitrosourea-induced gliomas in rats.
Topics: Animals; Biological Assay; Bleomycin; Brain Neoplasms; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1982 |
Antitumoral action of bovine seminal ribonuclease.
Topics: Animals; Antineoplastic Agents; Cattle; Cell Division; Cell Transformation, Viral; Cells, Cultured; Cricetinae; Ethylnitrosourea; Fibroblasts; Glioma; Humans; Mesocricetus; Neuroblastoma; Polyomavirus; Rats; Ribonucleases; Semen | 1981 |
Changing images of the brain.
Topics: Anatomy; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Glioma; History, 16th Century; History, 17th Century; History, 18th Century; History, 19th Century; History, Ancient; History, Medieval; History, Modern 1601-; Humans; Microscopy, Electron; Neoplasms, Experimental; Rats | 1983 |
Reduction of N-nitroso-N-ethylurea-induced neurogenic tumors by X-radiation: a life-span study in rats.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Glioma; Nervous System Neoplasms; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms; Whole-Body Irradiation | 1984 |
[Effect of orally administered zinc on the inducibility of experimental brain tumors in the rat].
Topics: Administration, Oral; Animals; Astrocytoma; Brain Neoplasms; Cocarcinogenesis; Ethylnitrosourea; Glioma; Male; Oligodendroglioma; Rats; Sarcoma; Zinc | 1984 |
[DNA levels in the cell nuclei of nervous system tumors induced by ethylnitrosourea].
Topics: Animals; DNA, Neoplasm; Ethylnitrosourea; Female; Glioma; Nervous System Neoplasms; Ploidies; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Trigeminal Nuclei | 1984 |
Regional blood flow in ethylnitrosourea-induced brain tumors.
Topics: Animals; Astrocytoma; Blood Flow Velocity; Brain Neoplasms; Cerebrovascular Circulation; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains; Regional Blood Flow | 1983 |
Regional blood-to-tissue transport in ethylnitrosourea-induced brain tumors.
Topics: Aminoisobutyric Acids; Animals; Astrocytoma; Blood-Brain Barrier; Brain; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Ethylnitrosourea; Female; Glioma; Kinetics; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Biochemical and histochemical evaluation of glycosaminoglycans in brain tumors induced in rats by nitrosourea derivatives.
Topics: Age Factors; Animals; Brain Neoplasms; Ethylnitrosourea; Glioma; Glycosaminoglycans; Histocytochemistry; Methylnitrosourea; Nitrosourea Compounds; Rats | 1983 |
Immunoradiometric and immunohistochemical demonstration of neuron-specific enolase in experimental rat gliomas.
Topics: Animals; Brain; Brain Neoplasms; Cell Line; Ethylnitrosourea; Glioma; Histocytochemistry; Humans; Neoplasms, Experimental; Neurilemmoma; Phosphopyruvate Hydratase; Radioimmunoassay; Rats | 1984 |
Microvascular abnormalities in ethylnitrosourea (ENU)-induced rat brain tumors: structural basis for altered blood-brain barrier function.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Endothelium; Ethylnitrosourea; Glioma; Horseradish Peroxidase; Intercellular Junctions; Microcirculation; Microscopy, Electron; Neoplasms, Experimental; Nitrosourea Compounds; Pinocytosis; Rats; Rats, Inbred Strains | 1983 |
Early stage of development of transplacentally induced glioma with ethylnitrosourea in rats. Sequential historadioautographic and electron microscopic studies.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Division; Ethylnitrosourea; Female; Fetal Diseases; Glioma; Microscopy, Electron; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Glycosaminoglycans of brain tumors transplacentally induced by ENU in the rat.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Glycosaminoglycans; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglia; Oligodendroglioma; Pregnancy; Rats | 1981 |
Natural cytotoxicity against chemically induced neurogenic rat tumors.
Topics: Age Factors; Animals; Brain Neoplasms; Cell Division; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Ethylnitrosourea; Female; Glioma; Immunity, Innate; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neurilemmoma; Rats; Spleen; T-Lymphocytes | 1982 |
[Immunoperoxidase method using antiserum against astroprotein for the diagnosis of experimental brain tumors (author's transl)].
Topics: Animals; Astrocytes; Brain Neoplasms; Ethylnitrosourea; Glioma; Humans; Immune Sera; Immunoenzyme Techniques; Neoplasm Proteins; Neoplasms, Experimental; Nerve Tissue Proteins; Rats | 1980 |
[The effects of combined chemotherapy (adriamycin/VM/26/CCNU) in brian tumours in adults and animal experiments (author's transl)].
Topics: Adult; Aged; Animals; Brain Neoplasms; Doxorubicin; Drug Therapy, Combination; Ethylnitrosourea; Female; Glioma; Humans; Intracranial Pressure; Lomustine; Male; Middle Aged; Neoplasms, Experimental; Nitrosourea Compounds; Podophyllotoxin; Rats; Survival | 1982 |
[Local cerebral glucose utilization in the ethylnitrosourea-induced rat glioma].
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Ethylnitrosourea; Glioma; Glucose; Neoplasms, Experimental; Rats | 1982 |
Regional blood flow and capillary permeability in the ethylnitrosourea-induced rat glioma.
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Glioma; Rats; Rats, Inbred Strains; Regional Blood Flow | 1981 |
Cell culture systems to study glial transformation.
Topics: Animals; Astrocytes; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Ethylnitrosourea; Female; Glioma; Humans; Maternal-Fetal Exchange; Neoplasms, Experimental; Neuroglia; Nitrosourea Compounds; Oligodendroglia; Pregnancy; Rats | 1980 |
Metastasis from the brain of transplanted N-ethyl-N-nitrosourea-induced central nervous system tumors in rats.
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Glioma; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
[Changes of blood-brain barrier in the ethylnitrosourea induced rat glioma (author's transl)].
Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Rats | 1981 |
[Regional blood flow in the ethylnitrosourea induced rat glioma (author's transl)].
Topics: Animals; Brain Neoplasms; Cerebrovascular Circulation; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
[Principal fields of research into the pathogenesis of gliomas (author's transl)].
Topics: Animals; Brain Neoplasms; DNA Tumor Viruses; Dogs; Ethylnitrosourea; Female; Glioma; Humans; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Retroviridae | 1981 |
LDH isozyme analyses of ethylnitrosourea-induced central nervous system tumors in rats.
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Isoenzymes; L-Lactate Dehydrogenase; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Rats; Spinal Cord | 1980 |
Role of nerve growth factor in ethylnitrosourea-induced neural carcinogenesis.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Hydroxydopamines; Neoplasms, Experimental; Nerve Growth Factors; Nitrosourea Compounds; Pregnancy; Rats | 1980 |
Contribution of O6-methylguanine-DNA methyltransferase to monofunctional alkylating-agent resistance in human brain tumor-derived cell lines.
Topics: Alkylating Agents; Antineoplastic Agents; Brain Neoplasms; Cell Adhesion; Colonic Neoplasms; Culture Media; Drug Resistance; Drug Screening Assays, Antitumor; Ethylnitrosourea; Glioma; Medulloblastoma; Methylation; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured | 1995 |
The RG2 rat glioma model.
Topics: Animals; Blood-Brain Barrier; Body Weight; Brain; Brain Neoplasms; Cell Transplantation; Ethylnitrosourea; Female; Glioma; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344; Sex Characteristics; Tumor Cells, Cultured | 1995 |
Immunohistochemical localization of glycosaminoglycans in experimental rat glioma models.
Topics: Animals; Brain Neoplasms; Chondroitin Sulfates; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioma; Immunohistochemistry; Keratan Sulfate; Male; Rats; Rats, Wistar | 1994 |
Transformation of type 1 astrocytes with N-ethyl-N-nitrosourea: establishment of an in vitro system and the role of the p53 gene.
Topics: Animals; Astrocytes; Brain; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; DNA Damage; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Genes, p53; Glioma; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Rats; Rats, Wistar; RNA, Neoplasm; Tumor Stem Cell Assay; Tumor Suppressor Protein p53 | 1995 |
Measurement of amino acid metabolism derived from [1-13C]glucose in the rat brain using 13C magnetic resonance spectroscopy.
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Ethylnitrosourea; Glioma; Glucose; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Rats; Rats, Wistar; Spinal Cord Neoplasms | 1994 |
Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas.
Topics: Acetylation; Acetyltransferases; Animals; Brain; Brain Neoplasms; Catalysis; Cytosol; Ethylnitrosourea; Female; Glioma; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spermidine | 1994 |
GFAP expression in the subcutaneous tumors of immature glial cell line (HITS glioma) derived from ENU-induced rat glioma.
Topics: Animals; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Insulin-Like Growth Factor I; Microscopy, Electron, Scanning Transmission; Neoplasm Transplantation; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Tumor Cells, Cultured | 1993 |
Diamine oxidase activity in rat brain carcinogenesis and in gliomas.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain Neoplasms; Ethylnitrosourea; Female; Fetus; Glioma; Male; Precancerous Conditions; Pregnancy; Prenatal Exposure Delayed Effects; Putrescine; Rats | 1993 |
Characterization of rat NCA/CD9 cell surface antigen and its expression by normal and malignant neural cells.
Topics: Alkaline Phosphatase; Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Blotting, Western; Cell Membrane; Enzyme-Linked Immunosorbent Assay; Ethylnitrosourea; Flow Cytometry; Fluorescent Antibody Technique, Direct; Glioma; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Nervous System Neoplasms; Neurilemmoma; Neurons; Phenotype; Rats; Tetraspanin 29 | 1996 |
VEGF and bFGF mRNA are expressed in ethylnitrosourea-induced experimental rat gliomas.
Topics: Animals; Base Sequence; Digoxigenin; Endothelial Growth Factors; Ethylnitrosourea; Female; Fibroblast Growth Factor 2; Glioma; In Situ Hybridization; Lymphokines; Male; Molecular Sequence Data; Neoplasms, Experimental; Neuroglia; Oligonucleotide Probes; Rats; Rats, Wistar; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Effects of basic fibroblast growth factor on in vivo cerebral tumorigenesis in rats.
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Fibroblast Growth Factor 2; Glioma; Humans; Male; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1997 |
Drug resistance and apoptosis in ENU-induced rat brain tumors treated with anti-cancer drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; DNA Nucleotidylexotransferase; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Nimustine; Pregnancy; Rats; Rats, Wistar; Vincristine | 1998 |
Glial tumoral proliferation induces changes in the state and physical properties of water during ENU-induction of brain tumors in rats.
Topics: Animals; Cell Division; Ethylnitrosourea; Female; Glioma; Magnetic Resonance Spectroscopy; Maternal-Fetal Exchange; Pregnancy; Rats; Temperature; Water | 1998 |
Effect of dietary vitamin A or N-acetylcysteine on ethylnitrosourea-induced rat gliomas.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Free Radical Scavengers; Glioma; Neuroectodermal Tumors; Pregnancy; Rats; Rats, Sprague-Dawley; Survival Analysis; Vitamin A | 1998 |
Molecular genetic characterisation of intracerebrally transplanted brain tumours.
Topics: Animals; Base Sequence; Brain Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA Primers; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Ethylnitrosourea; Genes, bcl-1; Genes, p16; Genes, Retinoblastoma; Glioma; Molecular Sequence Data; Neoplasm Transplantation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Rats; Rats, Inbred Strains | 1999 |
Laminin receptor alpha6beta4 integrin is highly expressed in ENU-induced glioma in rat.
Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Blood Vessels; Brain Neoplasms; Cell Division; Dimerization; Ethylnitrosourea; Female; Glioma; Humans; Integrin alpha6beta4; Integrins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic | 1999 |
Distribution and activity of transglutaminase in rat brain carcinogenesis and in gliomas.
Topics: Animals; Animals, Newborn; Brain; Brain Neoplasms; Carcinogenicity Tests; Carcinogens; Cytosol; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Subcellular Fractions; Time Factors; Transglutaminases | 1999 |
Allele-specific losses of heterozygosity on chromosomes 1 and 17 revealed by whole genome scan of ethylnitrosourea-induced BDIX x BDIV hybrid rat gliomas.
Topics: Alleles; Animals; Brain Neoplasms; Chimera; Chromosome Mapping; Chromosomes; Ethylnitrosourea; Genetic Linkage; Genetic Markers; Glioma; Humans; Loss of Heterozygosity; Rats; Rats, Inbred Strains | 1999 |
Evaluation of the potential promoting effect of 60 Hz magnetic fields on N-ethyl-N-nitrosourea induced neurogenic tumors in female F344 rats.
Topics: Animals; Body Weight; Brain Neoplasms; Central Nervous System Neoplasms; Electromagnetic Fields; Ethylnitrosourea; Female; Glioma; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Immunohistochemical analysis of beta-catenin in N-ethyl-N-nitrosourea-induced rat gliomas: implications in regulation of angiogenesis.
Topics: Animals; beta Catenin; Blood Vessels; Brain Neoplasms; Cytoskeletal Proteins; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Intracellular Membranes; Neovascularization, Pathologic; Nucleolus Organizer Region; Rats; Rats, Wistar; Reference Values; Silver; Staining and Labeling; Trans-Activators | 2000 |
The effects of 860 MHz radiofrequency radiation on the induction or promotion of brain tumors and other neoplasms in rats.
Topics: Animals; Brain Neoplasms; Cell Phone; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glioma; Male; Neoplasms; Neoplasms, Radiation-Induced; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Radio Waves; Rats; Rats, Sprague-Dawley; Spinal Cord Neoplasms; Spinal Nerves | 2001 |
Paradoxical effect of aspirin on the growth of C6 rat glioma and on time of development of ENU-induced tumors of the nervous system.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Carcinogens; Cell Division; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Glioma; Rats; Time Factors; Tumor Cells, Cultured | 2001 |
Magnetic resonance imaging of ethyl-nitrosourea-induced rat gliomas: a model for experimental therapeutics of low-grade gliomas.
Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Carcinogens; Diet; Disease Models, Animal; Diterpenes; Ethylnitrosourea; Glioma; Indoles; Magnetic Resonance Imaging; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Pyrroles; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Retinyl Esters; Survival Analysis; Time Factors; Vitamin A | 2001 |
Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethyl-nitrosourea exposure.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3; Caspase 9; Caspases; Ethylnitrosourea; Female; Gene Targeting; Genes, p53; Glioma; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Mice, Knockout; Neurons; Placenta; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Stem Cells | 2001 |
Spleen-cell reactivity against transplanted neurogenic rat tumors induced by ethylnitrosourea: uncovering of tumor specificity after removal of complement-receptor-bearing lymphocytes.
Topics: Animals; Cell Line; Cell Membrane; Complement C3; Complement System Proteins; Cross Reactions; Cytotoxicity Tests, Immunologic; Epitopes; Ethylnitrosourea; Glioma; Lymphocytes; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Rats; Rats, Inbred Strains; Receptors, Antigen, B-Cell; Spleen; Transplantation, Isogeneic | 1975 |
Chromosome analysis of experimental rat glial tumor(1)--correlation of chromosome changes between glial tumors and fetal brain tissue of rats after a transplacental exposure to ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Chromosomes; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
[Uptake of bleomycin by ethylnitrosourea-induced rat brain tumors (author's transl)].
Topics: Animals; Bleomycin; Brain Chemistry; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Neurilemmoma; Rats; Spinal Cord Neoplasms | 1979 |
Scanning electron microscopy of cloned astrocytic lines derived from ethylnitrosourea-induced rat gliomas.
Topics: Animals; Astrocytes; Cell Division; Cell Line; Ethylnitrosourea; Glioma; Microscopy, Electron, Scanning; Microvilli; Neoplasm Transplantation; Neuroglia; Rats | 1978 |
Macrophages in brain tumours induced transplacentally by N-ethyl-N-nitrosourea in rats: an electron-microscope study.
Topics: Animals; Brain Edema; Brain Neoplasms; Cerebral Hemorrhage; Ethylnitrosourea; Female; Glioma; Inclusion Bodies; Leukocytes; Lipids; Lysosomes; Macrophages; Microscopy, Electron; Mitosis; Monocytes; Myelin Sheath; Necrosis; Nerve Degeneration; Nitrosourea Compounds; Phagocytosis; Pregnancy; Rats | 1975 |
Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Ethylnitrosourea; Female; Fetal Diseases; Glioma; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats | 1976 |
The fine structure of blood vessels in ethylnitrosourea-induced tumours of the rat nervous system: with special reference to the breakdown of the blood-brain barrier.
Topics: Animals; Basement Membrane; Blood-Brain Barrier; Capillaries; Ethylnitrosourea; Female; Glioma; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neurilemmoma; Pregnancy; Rats | 1976 |
[Long-term cultures of experimental CNS tumours as models in neurooncological research (author's transl)].
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Division; Cell Transformation, Neoplastic; Culture Techniques; Ethylnitrosourea; Glioma; Methylnitrosourea; Neoplasms, Experimental; Neurilemmoma; Rats; Rats, Inbred Strains; Time Factors | 1976 |
[Transplacental induction of neurogenic tumors in rabbits (author's transl)].
Topics: Animals; Animals, Newborn; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neurilemmoma; Nitrosourea Compounds; Placenta; Pregnancy; Pregnancy, Animal; Rabbits; Time Factors | 1977 |
Morphologic and biochemical characteristics of transplantable neurogenic tumors induced by N-ethyl-N-nitrosourea in inbred BD IX rats.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain Neoplasms; Clone Cells; Ethylnitrosourea; Female; Glioma; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Rats, Inbred Strains; S100 Proteins; Transplantation, Isogeneic | 1979 |
Cellular heterogeneity in an ethylnitrosourea-induced glioma: malignancy, karyology and other properties of tumour cell types.
Topics: Animals; Brain Neoplasms; Bucladesine; Clone Cells; Ethylnitrosourea; Female; Glioma; Glucosephosphate Dehydrogenase; Karyotyping; Neoplasms, Experimental; Rats | 1979 |
Nitrosourea-induced brain tumors: an in vivo and in vitro tumor model system.
Topics: Animals; Brain Neoplasms; Cell Division; Cells, Cultured; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Immunosuppression Therapy; Male; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Thymus Gland; Time Factors; Transplantation, Isogeneic | 1978 |
Analysis of N-ethyl-N-nitrosourea-induced brain carcinogenesis by sequential culturing during the latent period. II. Morphology of the tumors induced by cell cultures.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Isogeneic | 1978 |
N-ethyl-N-nitrosourea-induced spinal tumors in an inbred strain of W albino rats.
Topics: Animals; Animals, Newborn; Astrocytoma; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1979 |
[Immunohistological diagnosis of human and experimental brain tumors using antiserum to astroprotein (author's transl)].
Topics: Animals; Astrocytoma; Brain Neoplasms; Cerebral Ventricle Neoplasms; Ethylnitrosourea; Fluorescent Antibody Technique; Glioma; Humans; Immune Sera; Neoplasm Proteins; Neoplasms, Experimental; Oligodendroglioma; Rats | 1979 |
Neuroblasts in cerebral tumors induced by ethylnitrosourea in rats. A fine structrual study.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Medulla Oblongata; Neoplasms, Experimental; Neuroglia; Neurons; Organoids; Pregnancy; Rats | 1977 |
The development of experimental brain tumours. A sequential light and electron microscope study of the subependymal plate. I. Early lesions (abnormal cell clusters).
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
The development of experimental brain tumours a sequential light and electron microscope study of the subependymal plate. II. Microtumours.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
Immunization against ethylnitrosourea-induced autochthonous neurogenic rat tumours.
Topics: Animals; Antigens, Neoplasm; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Immunization; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred F344 | 1979 |
Lactic dehydrogenase in ethylnitrosourea-induced rat gliomas. Total lactic dehydrogenase activity and isozymes in autochthonous gliomas and cloned transplantable astrocytomas.
Topics: Animals; Astrocytoma; Cells, Cultured; Ethylnitrosourea; Glioma; Glycolysis; Isoenzymes; L-Lactate Dehydrogenase; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Transplantation, Isogeneic | 1979 |
Cerebral tumours induced by ENU; changes of adenylate cyclase activity in the tumour latency time.
Topics: Adenylyl Cyclases; Animals; Brain Neoplasms; Brain Stem; Ethylnitrosourea; Female; Frontal Lobe; Glioma; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats; Temporal Lobe | 1979 |
[The biochemical analysis of the experimental tumor tissues of the rat brain induced by ethylnitrosourea (author's transl)].
Topics: Animals; Brain Chemistry; Brain Neoplasms; DNA, Neoplasm; Ethylnitrosourea; Fatty Acids, Nonesterified; Female; Glioma; Neoplasms, Experimental; Nitrosourea Compounds; Rats; RNA, Neoplasm | 1979 |
Excess chromosome no. 4 in ethylnitrosourea-induced neurogenic tumor lines of the rat.
Topics: Animals; Animals, Newborn; Cell Line; Chromosome Aberrations; Chromosomes, Human, 4-5; Ethylnitrosourea; Glioma; Humans; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Rats; Transplantation, Homologous; Trisomy | 1977 |
[Effect of irradiation to carcinogenesis by transplacental ethylnitrosourea in BD--IX rat (author's transl)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain Neoplasms; Cerebral Cortex; Embryo, Mammalian; Ethylnitrosourea; Female; Glioma; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats | 1978 |
Cerebral tumors induced by transplacental ENU: study of the different tumoral stages, particularly of early proliferations.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Time Factors | 1978 |
Fibrinolytic activity of cultured cells derived during ethylnitrosourea-induced carcinogenesis of rat brain.
Topics: Animals; Brain Neoplasms; Cell Line; Clone Cells; Ethylnitrosourea; Fibrinolysis; Glioma; Plasminogen; Rats; Time Factors | 1978 |
Activities of enzymes of the hexose monophosphate pathway in nervous system tumors induced by ethylnitrosourea.
Topics: Animals; Cerebral Cortex; Ethylnitrosourea; Female; Glioma; Glucosephosphate Dehydrogenase; Neoplasms, Experimental; Nervous System Diseases; Phosphogluconate Dehydrogenase; Rats; Transketolase | 1978 |
[Early stages of experimental brain tumours in rats. Investigation of serial sections (author's transl)].
Topics: Animals; Astrocytoma; Basal Ganglia; Brain Neoplasms; Brain Stem; Cerebral Cortex; Ethylnitrosourea; Female; Glioma; Hippocampus; Neoplasms, Experimental; Oligodendroglioma; Pregnancy; Rats; Sarcoma; Time Factors | 1978 |
Scanning electron microscopy of neoplastic neurogenic rat cell lines in culture.
Topics: Animals; Cell Line; Cell Membrane; Cells, Cultured; Ethylnitrosourea; Glioma; Microscopy, Electron, Scanning; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Rats; Transplantation, Homologous | 1978 |
[Experimental brain tumors produced transplacentally by ethylnitrosourea (IV): ultrastructure studied by using transmission and scanning electron microscope (author's transl)].
Topics: Animals; Cerebral Ventricle Neoplasms; Cerebral Ventricles; Ethylnitrosourea; Female; Glioma; Microscopy, Electron, Scanning; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Rats | 1978 |
The immunocytochemical localization of GFA protein in experimental murine CNS tumors.
Topics: Animals; Astrocytes; Brain Neoplasms; Cranial Nerve Neoplasms; Ependymoma; Ethylnitrosourea; Glioma; Methylcholanthrene; Neoplasms, Experimental; Nerve Tissue Proteins; Neurilemmoma; Oligodendroglioma; Rats; Spinal Cord Neoplasms; Trigeminal Nerve | 1979 |
Short and long term effects of methyl- and ethylnitrosourea (MNU & ENU) on the developing nervous system of the rat. I. Long term effects: the induction of (multiple) gliomas.
Topics: Age Factors; Animals; Animals, Newborn; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Male; Meningioma; Methylnitrosourea; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1977 |
The role of the subependymal plate in the origin of gliomas induced by ethylnitrosourea in the rat brain.
Topics: Animals; Brain; Brain Neoplasms; Corpus Callosum; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Neurons; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
Quantitative aspects of transplantation of experimentally induced tumors of the nervous system.
Topics: Animals; Cell Count; Ethylnitrosourea; Glioma; Neoplasm Transplantation; Neoplasms, Experimental; Nervous System Diseases; Rats; Time Factors; Transplantation, Homologous | 1977 |
A sequential in vivo-in vitro study of carcinogenesis induced in the rat brain by ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Glioma; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
The origin of experimental brain tumours: a sequential study.
Topics: Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
[Experimental brain neoplasm induced transplacentally by ethylnitrosourea (ENU). (1) Sequential, localized observations and pathological studies of microtumors].
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats | 1976 |
[Experimental brain neoplasm induced by ethylnitrosourea. Frequency of incidence and neurological manifestation in rats].
Topics: Aggression; Animals; Astrocytoma; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Humans; Meningioma; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Trigeminal Nerve | 1976 |
RNA polymerase activity in homotransplanted rat brain tumors initially induced by ethylnitrosourea.
Topics: Amanitins; Animals; Autoradiography; Brain Neoplasms; Cell Nucleolus; Cell Nucleus; Cycloheximide; DNA-Directed RNA Polymerases; DNA, Neoplasm; Endoplasmic Reticulum; Ethylnitrosourea; Fibrosarcoma; Glioma; Guanosine Triphosphate; Neoplasm Transplantation; Neoplasms, Experimental; Neurofibroma; Rats; Rifampin; Transplantation, Homologous | 1975 |
Oncogenic response of rats with x-ray-induced microcephaly to transplacental ethylnitrosourea.
Topics: Animals; Ependymoma; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Peripheral Nervous System Neoplasms; Pregnancy; Radiation Injuries, Experimental; Rats; Time Factors | 1976 |
Studies of the morphology and tumorigenicity of experimental brain tumours in tissue culture.
Topics: Animals; Brain Neoplasms; Culture Techniques; Ethylnitrosourea; Glioma; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1976 |
14-3-2 protein in rat primary and transplanted gliomas and neurinomas and in clonal cell lines.
Topics: Animals; Clone Cells; Ethylnitrosourea; Glioma; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Nerve Tissue Proteins; Nervous System Diseases; Neurilemmoma; Rats; Rats, Inbred Strains; Schwann Cells | 1976 |
[Effect of pretreatment with N-methyl-N-nitrosourea or streptozotocin on the cytotoxicity and the induction of sister chromatid exchanges in human and rodent brain tumor cells treated with chloroethylnitrosourea].
Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance; Drug Synergism; Ethylnitrosourea; Glioma; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Streptozocin; Tumor Cells, Cultured | 1992 |
Immunohistochemical observations on rat radial glia: relationship with the origin of ethylnitrosourea-induced tumors.
Topics: Animals; Astrocytes; Brain Neoplasms; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Microscopy, Immunoelectron; Neuroglia; Pregnancy; Rats; Rats, Inbred F344; Vimentin | 1992 |
Immunohistochemical localization of gangliosides in ENU-induced rat glioma.
Topics: Adult; Aging; Animals; Animals, Newborn; Brain; Brain Injuries; Brain Neoplasms; Embryonic and Fetal Development; Ethylnitrosourea; Female; Fetus; Gangliosides; Glioma; Humans; Immunohistochemistry; Infant, Newborn; Rats; Tissue Distribution; Wounds, Stab | 1992 |
Immunohistochemical characterization of rat central and peripheral nerve tumors induced by ethylnitrosourea.
Topics: Animals; Antigens, Differentiation; Astrocytoma; CD57 Antigens; Central Nervous System; Ependymoma; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Immunohistochemistry; Meningioma; Nervous System Neoplasms; Neurilemmoma; Oligodendroglioma; Peripheral Nervous System Neoplasms; Phosphopyruvate Hydratase; Rats; Rats, Inbred Strains; S100 Proteins | 1990 |
Molecular dosimetry of sister chromatid exchange induction in 9L cells treated with 6-thioguanine.
Topics: Alkylating Agents; Animals; DNA Damage; Dose-Response Relationship, Drug; Ethylnitrosourea; Glioma; Nimustine; Rats; Sister Chromatid Exchange; Thioguanine; Tumor Cells, Cultured | 1991 |
Expression of O6-methylguanine-DNA methyltransferase in malignant human glioma cell lines.
Topics: Blotting, Northern; Blotting, Southern; Blotting, Western; DNA; Ethylnitrosourea; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioma; Humans; Immunohistochemistry; Methyltransferases; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; RNA, Messenger; Tumor Cells, Cultured | 1991 |
3-Methyladenine DNA glycosylase activity in a glial cell line sensitive to the haloethylnitrosoureas in comparison with a resistant cell line.
Topics: DNA; DNA Glycosylases; Drug Resistance; Ethylnitrosourea; Glioma; N-Glycosyl Hydrolases; Tumor Cells, Cultured | 1991 |
Radioresistance of rat glioma cell lines cultured as multicellular spheroids. Correlation with electrical cell-to-cell-coupling.
Topics: Animals; Cell Communication; Cell Survival; Ethylnitrosourea; Glioma; Intercellular Junctions; Microelectrodes; Radiotherapy Dosage; Rats; Tumor Cells, Cultured | 1990 |
[Synthesis and animal experiments of ethylnitrosourea].
Topics: Animals; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glioma; Pregnancy; Rats; Rats, Inbred Strains; Trigeminal Nerve | 1990 |
Expression of vimentin and glial fibrillary acidic protein in ethylnitrosourea-induced rat gliomas and glioma cell lines.
Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Transformed; Epitopes; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioma; Intermediate Filaments; Neoplasm Transplantation; Nerve Tissue; Rats; Tumor Cells, Cultured; Vimentin | 1989 |
[Differences in microvasculature between ethylnitrosourea-induced brain tumor and transplanted 9L cell brain tumor in the rat].
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microcirculation; Microscopy, Electron; Neoplasm Transplantation; Rats; Rats, Inbred F344; Rats, Inbred Strains; Tumor Cells, Cultured | 1989 |
Glomeruloid blood vessels in ethylnitrosourea-induced rat gliomas. Histological and immunohistochemical studies.
Topics: Animals; Blood Vessels; Brain Neoplasms; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioma; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; von Willebrand Factor | 1989 |
A comparison of the effect of several factors on the plasminogen activator activity of cloned lines from an ethylnitrosourea-induced glioma and from normal tissue.
Topics: Animals; Brain Neoplasms; Cell Line; Cholera Toxin; Colforsin; Dexamethasone; Epidermal Growth Factor; Ethylnitrosourea; Glioma; Plasminogen Activators; Rats | 1989 |
Phenobarbital lacks promoting activity for neurogenic tumors in F344 rats transplacentally exposed to ethylnitrosourea.
Topics: Animals; Astrocytes; Ethylnitrosourea; Female; Gestational Age; Glioma; Male; Maternal-Fetal Exchange; Nervous System Neoplasms; Neurilemmoma; Oligodendroglia; Oligodendroglioma; Phenobarbital; Placenta; Pregnancy; Rats; Rats, Inbred F344 | 1989 |
Effect of chronic stress on ENU-induced tumors.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Pregnancy; Rats; Stress, Psychological | 1989 |
A sequential ultrastructural and histoautoradiographic study of early neoplastic lesions in ethylnitrosourea-induced rat glioma.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Glioma; Hyperplasia; Male; Microscopy, Electron; Neurons; Rats; Rats, Inbred Strains | 1989 |
Cloned neoplastic cells from a chemically-induced rat glioma: immunocytochemical characterization.
Topics: Animals; Astrocytes; Brain Neoplasms; Clone Cells; Ethylnitrosourea; Fibronectins; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glioma; Glutamate-Ammonia Ligase; Rats; Vimentin | 1985 |
Correlations between the degree and type of forebrain malformations and the simultaneous neuro-oncogenic properties of ethylnitrosourea after diaplacental exposure in rats, alone and in combination with X-irradiation.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1985 |
The effect of dexamethasone on vascular permeability of experimental brain tumours.
Topics: Animals; Brain Neoplasms; Capillary Permeability; Carbon Radioisotopes; Dexamethasone; Ethylnitrosourea; Female; Glioma; Kinetics; Male; Mannitol; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1986 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on neurogenic microtumors initiated by transplacental exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cocarcinogenesis; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Oligodendroglioma; Placenta; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1987 |
The effect of hyperosmotic blood-brain barrier disruption on blood-to-tissue transport in ENU-induced gliomas.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Blood-Brain Barrier; Cerebral Ventricle Neoplasms; Ethylnitrosourea; Glioma; Mannitol; Osmosis; Rats; Rats, Inbred Strains | 1987 |
The intraneoplastic chemotherapy in a rat brain tumour model utilizing methotrexate-polymethylmethacrylate-pellets.
Topics: Animals; Brain Neoplasms; Drug Carriers; Drug Implants; Ethylnitrosourea; Glioma; Methotrexate; Methylmethacrylates; Rats; Stereotaxic Techniques | 1987 |
Capillary permeability and boron distribution in ethylnitrosourea-induced rat glioma.
Topics: Animals; Boron; Brain; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Evans Blue; Glioma; Horseradish Peroxidase; Isotopes; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Vascular permeability and cell kinetics of ethylnitrosourea (ENU)-induced rat brain tumours.
Topics: Animals; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Glioma; Pharmacokinetics; Rats; Rats, Inbred Strains | 1988 |
Differences in DNA alkylation products formed in sensitive and resistant human glioma cells treated with N-(2-chloroethyl)-N-nitrosourea.
Topics: Alkylation; DNA; DNA Repair; Drug Resistance; Ethylnitrosourea; Glioma; Humans; Tumor Cells, Cultured | 1988 |
Intermediate filaments and anaplastic change of ENU-induced gliomass: immunohistochemical study with vimentin and astroprotein (GFAP).
Topics: Anaplasia; Animals; Astrocytoma; Brain Neoplasms; Cytoskeleton; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Immunohistochemistry; Intermediate Filaments; Oligodendroglioma; Rats; Rats, Inbred Strains; Vimentin | 1987 |
Effect of irradiation on ethyl nitrosourea induced neural tumours in Wistar rat.
Topics: Animals; Animals, Newborn; Cocarcinogenesis; Ethylnitrosourea; Glioma; Neoplasms, Multiple Primary; Neoplasms, Radiation-Induced; Nervous System Neoplasms; Neurilemmoma; Rats; Rats, Inbred Strains; Whole-Body Irradiation | 1986 |
Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea.
Topics: Animals; Brain; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Genes; Glioma; Maternal-Fetal Exchange; Oncogenes; Platelet-Derived Growth Factor; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Rats | 1986 |
Periphery of ethylnitrosourea-induced spinal gliomas in rats with special reference to the vascular structure.
Topics: Animals; Blood Vessels; Capillaries; Ethylnitrosourea; Glioma; Microscopy, Electron; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1987 |
Morphological and immunohistochemical evidence for the presence of subcortical target cells of N-ethyl-N-nitrosourea-induced cerebellar tumors in rats.
Topics: Animals; Animals, Newborn; Antibodies, Monoclonal; Cell Differentiation; Cerebellar Neoplasms; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Neuroglia; Rats | 1986 |
Inhibitory effect of phenobarbital on the development of gliomas in WF rats treated neonatally with N-ethyl-N-nitrosourea.
Topics: Animals; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Glioma; Male; Nitrosourea Compounds; Phenobarbital; Rats; Rats, Inbred WF; Sex Factors | 1985 |
Induction of gliomas in Mongolian gerbils (Meriones unguiculatus) following neonatal administration of N-ethyl-N-nitrosourea.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Ethylnitrosourea; Female; Gerbillinae; Glioma; Hemangioma; Kidney Neoplasms; Male; Melanoma; Nitrosourea Compounds; Odontogenic Tumors; Skin Neoplasms; Spinal Cord Neoplasms | 1985 |
[Induction of morphological changes and polyamine alterations in glioma cells by butyrate].
Topics: Animals; Butyrates; Butyric Acid; Chromatography, High Pressure Liquid; Ethylnitrosourea; Female; Glioma; Ornithine Decarboxylase; Polyamines; Rats; Rats, Inbred Strains | 1985 |
Morphological maturation of tumor cells induced by ethylnitrosourea (ENU) in rat brains. II. On the tumors by administration of ENU in the mid-gestational stage.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; Astrocytoma; Brain Neoplasms; Cell Differentiation; DNA Replication; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1985 |
Morphological maturation of tumor cells induced by ethylnitrosourea (ENU) in rat brains. I. On the tumors by administration of ENU in the late gestational stage.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1985 |
Current brain tumour models with particular consideration of the transplantation techniques. Outline of literature and personal preliminary results.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Glioma; Graft Survival; Intracranial Pressure; Male; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1986 |
Prognostic role of cell morphology of animal tumors.
Topics: Anaplasia; Animals; Cell Cycle; Cell Transformation, Neoplastic; Dog Diseases; Dogs; Ethylnitrosourea; Glioma; Neoplasms; Nerve Growth Factors; Prognosis; Trigeminal Nerve | 1985 |
[Immunohistochemical study of ethylnitrosourea-induced rat gliomas with vimentin and astroprotein (GFAP)].
Topics: Animals; Brain Chemistry; Brain Neoplasms; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Histocytochemistry; Rats; Rats, Inbred Strains; Vimentin | 1985 |
[Lysosomal enzymes in nitrosamine induced nervous system tumors of rats (author's transl)].
Topics: Acid Phosphatase; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Glucuronidase; Hexosaminidases; Lysosomes; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Sulfatases | 1974 |