Page last updated: 2024-08-21

ethylnitrosourea and Genetic Predisposition

ethylnitrosourea has been researched along with Genetic Predisposition in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (11.11)	18.2507
2000's	23 (51.11)	29.6817
2010's	16 (35.56)	24.3611
2020's	1 (2.22)	2.80

Authors

Authors	Studies
Bach, JF; Beutler, B; Bu, CH; Chatenoud, L; Hildebrand, S; Marquet, C; Moresco, EMY; Quan, J; Scott, L; Valette, F	1
Cleuren, AC; Ginsburg, D; Kotnik, EN; Saunders, TL; Siemieniak, DR; Tomberg, K; Westrick, RJ; Zhu, G	1
Abdel-Wahab, O; Bradley, RK; Durham, B; Fei, DL; Ferrarone, J; Garrett, L; Liu, P; Varmus, H; Yoshimi, A; Zhang, T; Zhen, T	1
Dahl, HH; Manji, SS; Miller, KA; Williams, LH	1
Bouriez-Jones, T; Bull, KR; Chaudhry, S; Cornall, RJ; Crockford, TL; Goodnow, CC; Hough, TA; Mason, T; Rimmer, AJ; Roberts, IS; Silver, KL	1
Anderton, S; Chen, G; Devine, W; Francis, R; Kim, AJ; Kim, Y; Leatherbury, L; Liu, X; Lo, CW; Morgan, J; Pratt, HC; Ramirez, R; Reinholdt, L; Subramanian, R; Tobita, K; Wong, L	1
Kuramoro, T; Mashimo, T; Ohno, Y; Sasa, M; Serikawa, T; Voigt, B	1
Abumrad, NN; Baek, JI; Choi, SY; Ess, KC; Flynn, CR; Gamse, JT; Hardiman, G; Kim, SH; Lipschutz, JH; Rockey, DC; Su, Y; Wu, SY	1
Fischer, C; Kindler-Röhrborn, A; Koelsch, B; Kutritz, A; van den Berg, L; Winzen-Reichert, B	1
Acevedo-Arozena, A; Brown, SD; Cox, RD; Kelly, M; Potter, P; Wells, S	1
Aigner, B; de Angelis, MH; Klaften, M; Klempt, M; Klopstock, T; Mayer, U; Michel, D; Rathkolb, B; Sedlmeier, R; Wagner, S; Wolf, E	1
Diwan, BA; Fortini, ME; Perantoni, AO; Rice, JM; Sharma, N; Timofeeva, O; Wang, H; Yang, Y	1
Beutler, B; Blasius, AL; Brandl, K; Eidenschenk, C; Khovananth, K; Krebs, P; Smart, NG; Xia, Y; Xiao, N	1
Jiang, YM; Liu, C; Shao, YX; Wu, LC	1
Beier, DR; Bjork, BC; Hentges, KE; Justice, MJ; Kamp, A; Moran, J; Moskowitz, IP; Peterson, MA; Rajapaksha, TW; Seidman, CE; Seidman, JG; Svenson, KL	1
Malo, D; Prendergast, C; Qureshi, ST; Richer, E; Vidal, SM; Zhang, DE	1
Chen, SY; Cheng, CY; Cheng, IH; Chou, CK; Chuang, YC; Hong, CJ; Hsu, CW; Jheng, HF; Lin, YT; Liou, YJ; Tsai, PJ; Tsai, SJ; Tsai, YS; Yang, CN	1
Chen, TH; Chen, YT; Huang, CC; Kao, HJ; Lin, WD; Sabbagha, NG; Tarn, WY; Tsai, FJ; Wu, JY; Yang, CF	1
Adams, DJ; Grati, M; Hilton, JM; Ingham, N; Laskowski, RA; Lewis, MA; Pearson, S; Steel, KP	1
Behr, MA; Berghout, J; Blanchette, M; Bongfen, SE; Cingolani, P; Gros, P; Gruenheid, S; Lathrop, M; Leiva-Torres, GA; Letourneau, L; Rodrigue-Gervais, IG; Saleh, M; Sladek, R; Torre, S; Vidal, SM; Wiltshire, SA	1
Canonne-Hergaux, F; Cellier, M; Chung, D; Eva, MM; Malo, D; Paquet, M; Richer, E; Vaulont, S; Vidal, SM; Yuki, KE	1
Hirose, M; Kashida, Y; Koujitani, T; Mitsumori, K; Watanabe, T; Yasuhara, K	1
Claij, N; Dekker, M; Jansen, L; te Riele, H; van der Wal, A	1
Bhakat, KK; Fujimoto, H; Kakinuma, S; Kobayash, K; Kubo, A; Nagai, J; Nishimura, M; Ogiu, T; Shimada, Y; Tano, K; Yoshinaga, S	1
Kashida, Y; Machida, N; Mitsumori, K; Muto, T; Okamura, M; Sumida, K; Watanabe, T	1
Aigner, B; de Angelis, MH; Klempt, M; Mohr, M; Rathkolb, B; Wolf, E	1
Cheng, KC; Gestl, EE; Moore, JL	1
Fischer, C; Kindler-Röhrborn, A; Koelsch, BU; Neibecker, M; Rajewsky, MF; Schmidt, O; Schmitt, N	1
Beutler, B; Croker, B; Crozat, K; Georgel, P; Jiang, Z; Rutschmann, S	1
Bogue, MA; Cheverud, JM; Edwin, D; Fenske, TS; Graubert, TA; Jarvis, JC; Mathews, V; McLeod, HL; McMahon, C; Minn, M; Province, MA	1
Beutler, B; Dahiyat, BI; Du, X; Hoebe, K; Mann, N; Rutschmann, S; Steed, P; Zalevsky, J	1
Breyer, MD; Davis, LS; Dunn, SR; Fogo, AB; Kadkina, V; Mohamed, Y; Polosukhina, D; Qi, Z; Rinchik, EM; Sharma, K; Tchekneva, EE	1
Choi, Y; Kendziorski, C; Kohlhepp, R; Moser, AR; Teske, D; Tess, A; Wang, H	1
Demant, P; Fijneman, RJ; Oomen, LC; Snoek, M	1
Dove, WF; Gould, MN; Haag, JD; Lindstrom, MJ; Mattes, EM; Moser, AR	1
Fischer, C; Held, S; Kindler-Röhrborn, A; Kölsch, BU; Rajewsky, MF	1
Adya, N; Anderson, S; Bodine, D; Castilla, LH; Dutra, A; Eckhaus, M; Garrett, L; Liu, PP; Orlic, D; Owens, J	1
Fischer, C; Kind, AB; Kindler-Röhrborn, A; Koelsch, BU; Rajewsky, MF	1
Balling, R; Hrabé de Angelis, M	1
Hegge, LF; Kohlhepp, RL; Moser, AR; Nett, JE	1
Barlow, C; Karabinis, ME; Larson, D; Moser, AR; Wynshaw-Boris, A	1
Cook, H; Kuraguchi, M; Thomas, GA; Williams, ED	1
Demant, P; Fijneman, RJ; Hart, AA; Tripodis, N	1
Held, S; Kindler-Röhrborn, A; Koelsch, BU; Rajewsky, MF; Zabel, S	1
Bauer-Hofmann, R; Buchmann, A; Drinkwater, NR; Luz, A; Mahr, J; Schwarz, M	1

Reviews

3 review(s) available for ethylnitrosourea and Genetic Predisposition

Article	Year
Advances on genetic rat models of epilepsy. Experimental animals, 2015, Volume: 64, Issue:1 Topics: Animals; Disease Models, Animal; Epilepsy; Ethylnitrosourea; Genetic Engineering; Genetic Predisposition to Disease; Genome; Intercellular Signaling Peptides and Proteins; Kv1.1 Potassium Channel; Models, Genetic; Mutagenesis; Mutation, Missense; NAV1.1 Voltage-Gated Sodium Channel; Phenotype; Proteins; Rats	2015
ENU mutagenesis, a way forward to understand gene function. Annual review of genomics and human genetics, 2008, Volume: 9 Topics: Animals; Breeding; DNA; Embryonic Stem Cells; Ethylnitrosourea; Female; Genes, Recessive; Genetic Predisposition to Disease; Humans; Infections; Male; Mice; Models, Animal; Models, Genetic; Mutagenesis; Mutagens; Mutation; Neurodegenerative Diseases; Phenotype	2008
Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV). Briefings in functional genomics & proteomics, 2005, Volume: 4, Issue:3 Topics: Animals; Cytokines; Cytomegalovirus Infections; Cytosol; Ethylnitrosourea; Genetic Predisposition to Disease; Genome; Germ-Line Mutation; Immunity, Innate; Macrophages; Mice; Muromegalovirus; Mutagenesis; Mutation; Phenotype; Point Mutation	2005

Other Studies

42 other study(ies) available for ethylnitrosourea and Genetic Predisposition

Article	Year
Modulation of autoimmune diabetes by N-ethyl-N-nitrosourea- induced mutations in non-obese diabetic mice. Disease models & mechanisms, 2022, 06-01, Volume: 15, Issue:6 Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Ethylnitrosourea; Genetic Predisposition to Disease; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mutation; Ubiquitin-Protein Ligases	2022
Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse. PLoS genetics, 2018, Volume: 14, Issue:9 Topics: Animals; Carrier Proteins; Disease Models, Animal; Ethylnitrosourea; Exome Sequencing; Factor V; Female; Genetic Predisposition to Disease; Heat-Shock Proteins; Humans; Kaplan-Meier Estimate; Lipoproteins; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Pedigree; Penetrance; Phospholipase C beta; Venous Thromboembolism	2018
Impaired hematopoiesis and leukemia development in mice with a conditional knock-in allele of a mutant splicing factor gene Proceedings of the National Academy of Sciences of the United States of America, 2018, 10-30, Volume: 115, Issue:44 Topics: Alleles; Animals; Core Binding Factor Alpha 2 Subunit; Ethylnitrosourea; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Hematopoiesis; Humans; Leukemia; Mice; Mice, Transgenic; Mutation; Myelodysplastic Syndromes; RNA Splicing; Splicing Factor U2AF	2018
Characterization of a novel ENU-generated myosin VI mutant mouse strain with congenital deafness and vestibular dysfunction. Hearing research, 2013, Volume: 299 Topics: Amino Acid Sequence; Animals; Auditory Perception; Base Sequence; Cardiomyopathy, Hypertrophic; Cochlea; Deafness; Disease Models, Animal; Ethylnitrosourea; Genetic Predisposition to Disease; Hearing Tests; Homozygote; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron, Scanning; Molecular Sequence Data; Mutagens; Mutation; Myosin Heavy Chains; Phenotype; Vestibule, Labyrinth	2013
Next-generation sequencing to dissect hereditary nephrotic syndrome in mice identifies a hypomorphic mutation in Lamb2 and models Pierson's syndrome. The Journal of pathology, 2014, Volume: 233, Issue:1 Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; DNA Mutational Analysis; Ethylnitrosourea; Eye Abnormalities; Genetic Association Studies; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Kidney Tubules; Laminin; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Myasthenic Syndromes, Congenital; Nephrotic Syndrome; Pedigree; Phenotype; Proteinuria; Pupil Disorders	2014
Interrogating congenital heart defects with noninvasive fetal echocardiography in a mouse forward genetic screen. Circulation. Cardiovascular imaging, 2014, Volume: 7, Issue:1 Topics: Animals; Disease Models, Animal; Echocardiography, Doppler; Echocardiography, Doppler, Color; Ethylnitrosourea; Female; Fetal Heart; Genetic Predisposition to Disease; Genetic Testing; Heart Defects, Congenital; Heredity; High-Throughput Screening Assays; Male; Mice; Mice, Inbred C57BL; Microscopy, Acoustic; Mutation; Pedigree; Phenotype; Ultrasonography, Prenatal	2014
A post-developmental genetic screen for zebrafish models of inherited liver disease. PloS one, 2015, Volume: 10, Issue:5 Topics: Animals; Disease Models, Animal; Ethylnitrosourea; Genetic Predisposition to Disease; Genetic Testing; Humans; Liver; Mutation; Non-alcoholic Fatty Liver Disease; Zebrafish	2015
Chemically Induced Oncogenesis in the Peripheral Nervous System Is Suppressed in Congenic BDIX.BDIV-Mss1 and -Mss7 Rats. G3 (Bethesda, Md.), 2015, Nov-03, Volume: 6, Issue:1 Topics: Alleles; Animals; Breeding; Carcinogenesis; Chromosome Mapping; Ethylnitrosourea; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genome; Incidence; Male; Peripheral Nervous System Neoplasms; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Rats; Rats, Inbred Strains	2015
Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models. Experimental physiology, 2009, Volume: 94, Issue:4 Topics: Alanine Transaminase; Alkaline Phosphatase; alpha-Amylases; Animals; Aspartate Aminotransferases; Creatine Kinase; Dystrophin; Enzymes; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Heredity; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Skeletal; Mutagenesis; Mutagens; Phenotype	2009
Inheritance of susceptibility to induction of nephroblastomas in the Noble rat. Differentiation; research in biological diversity, 2009, Volume: 77, Issue:4 Topics: Alkylating Agents; Animals; Blotting, Western; Breeding; Ethylnitrosourea; Female; Gene Expression Profiling; Genetic Predisposition to Disease; Kidney; Kidney Neoplasms; Male; Mutation; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Proteins; Wilms Tumor; WT1 Proteins	2009
The Tpl2 mutation Sluggish impairs type I IFN production and increases susceptibility to group B streptococcal disease. Journal of immunology (Baltimore, Md. : 1950), 2009, Dec-15, Volume: 183, Issue:12 Topics: Animals; Ethylnitrosourea; Genetic Predisposition to Disease; Herpesviridae Infections; Interferon Type I; Listeriosis; Male; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muromegalovirus; Mutagenesis; Proto-Oncogene Proteins; RNA Splicing; Signal Transduction; Streptococcal Infections; Streptococcus agalactiae	2009
[Fine mapping of mutant gene related corneal opacity mouse with SNPs]. Yi chuan = Hereditas, 2010, Volume: 32, Issue:5 Topics: Animals; Chromosome Mapping; Chromosomes, Mammalian; Corneal Opacity; Crosses, Genetic; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Male; MAP Kinase Kinase Kinase 1; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutagenesis; Mutation; Polymerase Chain Reaction; Polymorphism, Single Nucleotide	2010
Genome-wide identification of mouse congenital heart disease loci. Human molecular genetics, 2010, Aug-15, Volume: 19, Issue:16 Topics: Animals; Animals, Newborn; Chromosome Mapping; Crosses, Genetic; Disease Models, Animal; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Genetic Testing; Genome-Wide Association Study; Heart Defects, Congenital; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Myocardium	2010
N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium. Journal of immunology (Baltimore, Md. : 1950), 2010, Sep-15, Volume: 185, Issue:6 Topics: Animals; Endopeptidases; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Immunity, Innate; Interferon-alpha; Interferon-beta; Interferon-gamma; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mutagens; Mutation, Missense; Phosphorylation; Salmonella Infections, Animal; Salmonella typhimurium; Signal Transduction; STAT4 Transcription Factor; Ubiquitin; Ubiquitin Thiolesterase	2010
ENU mutagenesis identifies mice with morbid obesity and severe hyperinsulinemia caused by a novel mutation in leptin. PloS one, 2010, Dec-09, Volume: 5, Issue:12 Topics: Animals; Body Weight; Ethylnitrosourea; Evolution, Molecular; Exons; Genetic Predisposition to Disease; Homozygote; Humans; Hyperinsulinism; Leptin; Mice; Mutagenesis; Mutation; Obesity, Morbid; Receptors, Leptin	2010
Alternative splicing in Acad8 resulting a mitochondrial defect and progressive hepatic steatosis in mice. Pediatric research, 2011, Volume: 70, Issue:1 Topics: Acyl-CoA Dehydrogenase; Alternative Splicing; Amino Acid Metabolism, Inborn Errors; Animals; Base Sequence; Cold Temperature; Disease Models, Animal; Disease Progression; DNA Mutational Analysis; Ethylnitrosourea; Fatty Liver; Gene Expression Regulation, Enzymologic; Genetic Predisposition to Disease; Liver X Receptors; Male; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron, Transmission; Mitochondria, Liver; Mitochondrial Swelling; Molecular Sequence Data; Mutagens; Mutation; Orphan Nuclear Receptors; Oxidoreductases Acting on CH-CH Group Donors; Phenotype; PPAR alpha; PPAR gamma; RNA, Messenger; Thermogenesis; Thermosensing	2011
Exome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch mice. Genome biology, 2011, Sep-21, Volume: 12, Issue:9 Topics: Animals; Ear, Middle; Ethylnitrosourea; Evoked Potentials, Auditory, Brain Stem; Exome; Female; Genetic Predisposition to Disease; Immunohistochemistry; Inbreeding; LIM-Homeodomain Proteins; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mutation, Missense; Otitis Media; Pedigree; Penetrance; Point Mutation; Protein Structure, Secondary; Sequence Analysis, DNA; Transcription Factors	2011
An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria. PloS one, 2012, Volume: 7, Issue:2 Topics: Adoptive Transfer; Amino Acid Sequence; Animals; Chromosomes, Mammalian; Citrobacter; Ethylnitrosourea; Female; Genes, Dominant; Genetic Predisposition to Disease; Heterozygote; Homozygote; Immunophenotyping; Janus Kinase 3; Malaria, Cerebral; Male; Mice; Mice, Neurologic Mutants; Molecular Sequence Data; Mutation; Mycobacterium; Pedigree; Phenotype; Plasmodium berghei; Protein Structure, Tertiary; Spleen	2012
Suppression of hepcidin expression and iron overload mediate Salmonella susceptibility in ankyrin 1 ENU-induced mutant. PloS one, 2013, Volume: 8, Issue:2 Topics: Anemia, Hemolytic; Animals; Ankyrins; Antimicrobial Cationic Peptides; Codon, Nonsense; Erythrocytes; Erythropoietin; Ethylnitrosourea; Gene Expression; Genetic Predisposition to Disease; Growth Differentiation Factor 15; Heme Oxygenase-1; Hepcidins; Heterozygote; Homozygote; Iron; Iron Overload; Liver; Membrane Proteins; Mice; Salmonella Infections; Salmonella typhimurium; Survival Analysis	2013
Rapid induction of uterine endometrial proliferative lesions in transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) given a single intraperitoneal injection of N-ethyl-N-nitrosourea. Cancer letters, 2002, Dec-15, Volume: 188, Issue:1-2 Topics: Adenocarcinoma; Alkylating Agents; Animals; Endometrial Neoplasms; Ethylnitrosourea; Female; Genes, ras; Genetic Predisposition to Disease; Injections, Intraperitoneal; Mice; Mice, Inbred CBA; Mice, Transgenic; Point Mutation	2002
DNA mismatch repair deficiency stimulates N-ethyl-N-nitrosourea-induced mutagenesis and lymphomagenesis. Cancer research, 2003, May-01, Volume: 63, Issue:9 Topics: Alkylating Agents; Animals; Base Pair Mismatch; DNA Repair; DNA-Binding Proteins; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Hypoxanthine Phosphoribosyltransferase; Lymphoma; Male; Mice; Mutagenesis; MutS Homolog 2 Protein; Pregnancy; Proto-Oncogene Proteins	2003
Genetic susceptibility to thymic lymphomas and K-ras gene mutation in mice after exposure to X-rays and N-ethyl-N-nitrosourea. International journal of radiation biology, 2003, Volume: 79, Issue:6 Topics: Alkylating Agents; Animals; CD3 Complex; CD4 Antigens; CD8 Antigens; Codon; Enzyme Activation; Ethylnitrosourea; Female; Flow Cytometry; Genes, ras; Genetic Predisposition to Disease; Immunoblotting; Lymphoma; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Fluorescence; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Thymus Neoplasms; X-Rays	2003
Analysis of gene expression profiles of forestomach tumors in rasH2 mice initiated with N-ethyl-N-nitrosourea. Archives of toxicology, 2004, Volume: 78, Issue:12 Topics: Animals; Ethylnitrosourea; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms	2004
Hypercholesterolemia in ENU-induced mouse mutants. Journal of lipid research, 2004, Volume: 45, Issue:11 Topics: Alleles; Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Disease Models, Animal; Ethylnitrosourea; Genes, Dominant; Genes, Recessive; Genetic Predisposition to Disease; Hypercholesterolemia; Mice; Mice, Inbred C3H; Mutagenesis; Mutagens; Mutation; Phenotype	2004
Mosaic eyes, genomic instability mutants, and cancer susceptibility. Methods in cell biology, 2004, Volume: 76 Topics: Animals; Animals, Genetically Modified; DNA; Ethylnitrosourea; Eye; Frameshift Mutation; Genetic Predisposition to Disease; Genetic Vectors; Genomic Instability; Histological Techniques; Luminescent Proteins; Mutagenesis; Mutation; Neoplasms; Phenotype; Retina; Retinal Pigments; Tissue Fixation; Zebrafish	2004
Gender-specific polygenic control of ethylnitrosourea-induced oncogenesis in the rat peripheral nervous system. International journal of cancer, 2006, Jan-01, Volume: 118, Issue:1 Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Chromosome Mapping; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Male; Multifactorial Inheritance; Neurilemmoma; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred Strains; Sex Factors	2006
Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice. Cancer research, 2006, May-15, Volume: 66, Issue:10 Topics: Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Cocarcinogenesis; Ethylnitrosourea; Genetic Predisposition to Disease; Hematologic Neoplasms; Lung Neoplasms; Mice; Mice, Inbred Strains; Mutagens; Neoplasms, Experimental; Quantitative Trait Loci	2006
PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development. Journal of immunology (Baltimore, Md. : 1950), 2006, Jun-15, Volume: 176, Issue:12 Topics: Alleles; Amino Acid Substitution; Animals; Ethylnitrosourea; Female; Genes, Dominant; Genetic Predisposition to Disease; Germ-Line Mutation; Listeriosis; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Mutation, Missense; Peyer's Patches; Proline; Protein Binding; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Solubility; Spleen; Threonine; Tumor Necrosis Factor Decoy Receptors; Tumor Necrosis Factor-alpha	2006
A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy. Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:1 Topics: Albuminuria; Animals; Diabetic Nephropathies; Disease Models, Animal; Ethylnitrosourea; Female; Genes, Dominant; Genetic Predisposition to Disease; Genetic Testing; Humans; Insulin; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagens; Mutation; Phenotype; Sensitivity and Specificity	2007
Identification of novel modifier loci of Apc Min affecting mammary tumor development. Cancer research, 2007, Dec-01, Volume: 67, Issue:23 Topics: Alkylating Agents; Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Effect Modifier, Epidemiologic; Ethylnitrosourea; Female; Genes, APC; Genetic Predisposition to Disease; Hyperplasia; Intestinal Neoplasms; Male; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL	2007
A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H2 complex. Immunogenetics, 1995, Volume: 41, Issue:2-3 Topics: Animals; Chromosome Mapping; Ethylnitrosourea; Female; Genetic Predisposition to Disease; H-2 Antigens; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Pulmonary Alveoli; Recombination, Genetic	1995
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias. Proceedings of the National Academy of Sciences of the United States of America, 1993, Oct-01, Volume: 90, Issue:19 Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Crosses, Genetic; Ethylnitrosourea; Female; Genes, APC; Genetic Predisposition to Disease; Hyperplasia; Male; Mammary Glands, Animal; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Metaplasia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Point Mutation	1993
Ethylnitrosourea-induced development of malignant schwannomas in the rat: two distinct loci on chromosome of 10 involved in tumor susceptibility and oncogenesis. Cancer research, 1999, Mar-01, Volume: 59, Issue:5 Topics: Animals; Carcinogens; Chromosome Mapping; Crosses, Genetic; Disease-Free Survival; Ethylnitrosourea; Female; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Genotype; Male; Neurilemmoma; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Rats; Rats, Inbred Strains; Sequence Deletion	1999
The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nature genetics, 1999, Volume: 23, Issue:2 Topics: Animals; Cell Differentiation; Ethylnitrosourea; Genetic Predisposition to Disease; Granulocytes; Hematopoiesis; Leukemia, Myelomonocytic, Acute; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mutagens; Oncogene Proteins, Fusion	1999
Suppression of ethylnitrosourea-induced schwannoma development involves elimination of neu/erbB-2 mutant premalignant cells in the resistant BDIV rat strain. Cancer research, 2000, Sep-01, Volume: 60, Issue:17 Topics: Alleles; Animals; Carcinogens; Cranial Nerve Neoplasms; Crosses, Genetic; Ethylnitrosourea; Female; Genes, erbB-2; Genetic Predisposition to Disease; Male; Neurilemmoma; Point Mutation; Precancerous Conditions; Rats; Rats, Inbred Strains; Trigeminal Nerve	2000
From developmental biology to developmental toxicology. Annals of the New York Academy of Sciences, 2000, Volume: 919 Topics: Animals; Developmental Biology; Drosophila; Drug Resistance; Ethylnitrosourea; Genetic Predisposition to Disease; Genome, Human; Genotype; Humans; Mice; Mutagenesis; Mutagens; Phenotype; Toxicology; Xenobiotics	2000
ROSA26 mice carry a modifier of Min-induced mammary and intestinal tumor development. Mammalian genome : official journal of the International Mammalian Genome Society, 2000, Volume: 11, Issue:12 Topics: Animals; Base Sequence; DNA Primers; Ethylnitrosourea; Female; Genes, APC; Genetic Predisposition to Disease; Intestinal Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Mice, Mutant Strains	2000
Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in Apc(Min)/+ mice. Carcinogenesis, 2001, Volume: 22, Issue:2 Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA Primers; DNA-Binding Proteins; Ethylnitrosourea; Female; Genes, BRCA1; Genetic Predisposition to Disease; Incidence; Loss of Heterozygosity; Mammary Neoplasms, Experimental; Mice; Mice, Knockout; Mutation; Phenotype; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Tumor Suppressor Proteins	2001
Differences in susceptibility to colonic stem cell somatic mutation in three strains of mice. The Journal of pathology, 2001, Volume: 193, Issue:4 Topics: 1,2-Dimethylhydrazine; Animals; Cell Transformation, Neoplastic; Colon; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Mutation; Species Specificity; Stem Cells	2001
Complexity of lung cancer modifiers: mapping of thirty genes and twenty-five interactions in half of the mouse genome. Journal of the National Cancer Institute, 2001, Oct-03, Volume: 93, Issue:19 Topics: Animals; Animals, Congenic; Carcinogens; Chromosome Mapping; Ethylnitrosourea; Female; Genes; Genetic Predisposition to Disease; Genome; Genotype; Immunity, Innate; Karyotyping; Lung Neoplasms; Mice; Mice, Inbred C57BL; Phenotype; Pregnancy	2001
Loss of heterozygosity in malignant rat schwannomas chemically induced in hybrids of inbred rat strains with differential tumor susceptibility. Carcinogenesis, 2002, Volume: 23, Issue:6 Topics: Alleles; Animals; Carcinogens; Central Nervous System Neoplasms; Chromosome Mapping; Ethylnitrosourea; Gene Deletion; Genetic Markers; Genetic Predisposition to Disease; Loss of Heterozygosity; Neurilemmoma; Polymerase Chain Reaction; Rats; Rats, Inbred Strains	2002
Mutational activation of the c-Ha-ras gene in liver tumors of different rodent strains: correlation with susceptibility to hepatocarcinogenesis. Proceedings of the National Academy of Sciences of the United States of America, 1991, Feb-01, Volume: 88, Issue:3 Topics: Animals; Base Sequence; Codon; Diethylnitrosamine; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Polymerase Chain Reaction; Precancerous Conditions; Rats; Rats, Inbred Strains; Species Specificity	1991