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ethylnitrosourea and Cell Transformation, Neoplastic

ethylnitrosourea has been researched along with Cell Transformation, Neoplastic in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199056 (62.92)18.7374
1990's13 (14.61)18.2507
2000's12 (13.48)29.6817
2010's8 (8.99)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiba, M; Fujino, T; Kobayashi, Y; Koga, T; Mitsudomi, T; Nishino, M; Ohara, S; Shimoji, M; Suda, K; Takemoto, T; Tomizawa, K1
Bodakuntla, S; Lahiri, M; Libi, AV; Sural, S; Trivedi, P1
Fan, L; Harris, LC; Rehg, JE; Schuster, K; Volk, EL1
Basak, P; Chaklader, M; Chatterjee, S; Chaudhuri, S; Das, M; Das, P; Dutta, RK; Law, S; Pereira, JA1
Calaoagan, JM; Jang, T; Kwon, E; Laderoute, KR; Recht, L; Samuelsson, S1
Acharya, S; Begum, Z; Chatterjee, S; Chaudhuri, S; Dasgupta, S; Flora, SJ; Kumar, P1
Fischer, C; Kindler-Röhrborn, A; Koelsch, B; Kutritz, A; van den Berg, L; Winzen-Reichert, B1
Clipson, L; Dove, WF; Halberg, RB; Newton, MA; Plesh, L; Skinner, BL; Sullivan, R; Thliveris, AT; Waggoner, J; White, A; Zahm, CD1
Amasaki, Y; Fujimoto, S; Hino, O; Hirano, S; Imaoka, T; Kakinuma, S; Nishimura, M; Shimada, Y1
Dairkee, SH; Li, Z; Ljung, BM; Meng, ZH; Sayeed, A; Shalaby, R1
Bjerkvig, R; Eliasson, C; Pekny, M; Wilhelmsson, U1
Doi, K; Katayama, K; Nagata, T; Nakayama, H; Ueno, M; Yamauchi, H1
Fischer, C; Kindler-Röhrborn, A; Koelsch, BU; Neibecker, M; Rajewsky, MF; Schmidt, O; Schmitt, N1
Bonten, J; Carella, C; Grosveld, GC; Neale, G; Potter, M; Rehg, JE1
Casaccia-Bonnefil, P; Garcia-Verdugo, JM; Gil-Perotin, S; Li, J; Marin-Husstege, M; Roussel, MF; Soriano-Navarro, M; Zindy, F1
Baginskaia, NV; Il'nitskaia, SI; Kaledin, VI; Kholodar', AV; Obut, TA1
Fischer, C; Gering, KM; Kindler-Röhrborn, A; Lennartz, K; Marx, JA; Rajewsky, MF1
Fox, RR; Hard, GC2
Cravioto, H; Kageyama, N; Kida, Y; Kobayashi, T; Ransohoff, J; Shibuya, N; Yoshida, J1
De Ridder, L; Laerum, OD; Mørk, SJ1
Hayashi, K1
Alitalo, K; Hautanen, A; Keski-Oja, J; Rapp, UR1
Camp, RC; Capen, CC; Koestner, A; Vinores, SA1
Paoletti, P; Schiffer, D1
Kokunai, T; Matsumoto, S; Tamaki, N; Taomoto, K1
Singer, B3
Cervós-Navarro, J; Kroh, H1
Cravioto, H; Ransohoff, J; Yoshida, J1
de Ridder, L; Laerum, OD; Rajewsky, MF1
Rajewsky, MF1
Erickson, LC; Kohn, KW; Laurent, G; Sharkey, NA1
Cowing, D; Finkelstein, R; Padhy, LC; Shih, C; Weinberg, RA1
Owsianka, AM; Roscoe, JP1
Claisse, PJ; Hince, TA; Roscoe, JP; Winslow, DP1
Bressler, JP; Cole, R; de Vellis, J1
Bock, E; Haugen, A; Laerum, OD1
Claisse, PJ; Roscoe, JP1
Arita, N; Hayakawa, T; Higuchi, M; Hiraga, S; Izumoto, S; Ohnishi, T; Taki, T; Yamamoto, H1
Coca, S; Oya, S; Vaquero, J; Zurita, M1
Aguilar, F; Cerutti, P; Hussain, P; Pourzand, C1
Brüstle, O; Höll, T; Kleihues, P; Petersen, I; Plate, KH; Radner, H; Wiestler, OD1
Flesken-Nikitin, A; Jin, JJ; Nikitin, AY; Papewalis, J; Pozharisski, KM; Prokopenko, SN; Rajewsky, MF; Winterhager, E1
Bederson, JB; Germano, IM; Segal, DH1
Bilzer, T; Blass-Kampmann, S; Rajewsky, MF1
Geiger, M; Kindler-Röhrborn, A; Lennartz, K; Rajewsky, MF1
Anderson, LM; Buzard, GS; Devor, DE; Enomoto, T; Perantoni, AO; Rice, JM1
Cook, H; Kuraguchi, M; Thomas, GA; Williams, ED1
Stoica, G2
Thust, R1
Haglid, KG; Haugen, A; Laerum, OD; Rajewsky, MF; Schachner, M; Stavrou, D1
Haugen, A; Laerum, OD2
Asofsky, R; Kim, KJ; Mathieson, BJ; McKeever, PE; Weinbaum, FI1
Coutelle, R; Herrmann, V; Schreiber, D1
Haugen, A; Matre, R1
Taomoto, K1
Roscoe, JP; Rowles, PM; Winslow, DP1
Ostrovskaia, LA; Vermel', EM1
Laerum, OD; Rajewsky, MF1
Salamon, DP; Wani, AA; Yamasaki, EF1
Pitot, HC; Sattler, GL; Xu, YH; Zhang, JS1
Ballering, LA; Lyons, J; Rajewsky, MF1
Eberle, G; Huh, NH; Nehls, P; Rajewsky, MF; Thomale, J1
Chang, GT; de Kok, AJ; Sips, H; Verheijen, JH1
Chitale, AR; Deshpande, RB; Hasgekar, NN; Lalitha, VS1
Choudhury, S; Howett, MK; Kreider, JW; Mayo, DR; Pegg, AE1
Campanile, G; Capurro, G; Cipolla, M; Muratore, O; Rossi, L; Varnier, OE1
Aguzzi, A; Burger, PC; Kleihues, P; Shibata, T2
Ikeda, T; Iwasaki, K; Mashimoto, H; Matsuo, T; Shimokawa, I1
Bargmann, CI; Hung, MC; Weinberg, RA1
Cooper, CS; Newbold, RF; Shiner, AC1
Green, LJ; Roscoe, JP; Rumsby, PC1
Vinores, SA1
Guo, LP; Liu, YL; Lu, SZ; Luo, ZY; Su, ZZ1
de Kok, AJ; Den Engelse, L; Simons, JW; Sips, HM1
Kadlubar, FF; Kumari, L; Lehman, TA; Milo, GE; Noyes, I; Oldham, JW; West, RW1
O'Leary, M; Stoica, G1
Altena, B; Lens, PF; Nusse, R1
de Kok, AJ; den Engelse, L; Simons, JW; Sips, H1
Kokunai, T; Korosue, K; Matsumoto, S; Tamaki, N1
Bock, E; Haglid, K; Haugen, A; Laerum, OD; Mørk, SJ; Rosengren, L1
Koestner, A1
de Kok, AJ; Den Engelse, L; Simons, JW; Tates, AD1
de Kok, AJ; Den Engelse, L; Simons, JW; van Zeeland, AA1

Reviews

4 review(s) available for ethylnitrosourea and Cell Transformation, Neoplastic

ArticleYear
The transformation process.
    Progress in experimental tumor research, 1984, Volume: 27

    Topics: Animals; Brain; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Humans; Hyperplasia; Karyotyping; Neoplasm Invasiveness; Neoplasm Staging; Nerve Tissue Proteins; Plasminogen Activators

1984
Possible determinants for the differential susceptibility of mammalian cells and tissues to chemical carcinogens.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1980, Volume: 3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; Ethylnitrosourea; Phenotype; Rats

1980
Mutagenesis of the H-ras protooncogene and the p53 tumor suppressor gene.
    Cancer research, 1994, Apr-01, Volume: 54, Issue:7 Suppl

    Topics: Aflatoxin B1; Base Sequence; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Codon; DNA Primers; Ethylnitrosourea; Genes, p53; Genes, ras; Humans; Liver Neoplasms; Molecular Sequence Data; Mutagenesis; Neoplasms; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Proto-Oncogenes; Urinary Bladder Neoplasms

1994
N-nitroso alkylating agents: formation and persistence of alkyl derivatives in mammalian nucleic acids as contributing factors in carcinogenesis.
    Journal of the National Cancer Institute, 1979, Volume: 62, Issue:6

    Topics: Alkylating Agents; Animals; Binding Sites; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Repair; DNA, Single-Stranded; Ethylnitrosourea; Humans; Mutagens; Nitroso Compounds; Structure-Activity Relationship

1979

Other Studies

85 other study(ies) available for ethylnitrosourea and Cell Transformation, Neoplastic

ArticleYear
Sensitivity and Resistance of MET Exon 14 Mutations in Lung Cancer to Eight MET Tyrosine Kinase Inhibitors In Vitro.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2019, Volume: 14, Issue:10

    Topics: Alkylating Agents; Cell Transformation, Neoplastic; Cells, Cultured; Drug Resistance, Neoplasm; Ethylnitrosourea; Exons; Humans; In Vitro Techniques; Interleukin-3; Leukemia; Lung Neoplasms; Mutation; Precursor Cells, B-Lymphoid; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-met

2019
N-nitroso-N-ethylurea activates DNA damage surveillance pathways and induces transformation in mammalian cells.
    BMC cancer, 2014, Apr-24, Volume: 14

    Topics: Ataxia Telangiectasia Mutated Proteins; Cell Cycle Checkpoints; Cell Transformation, Neoplastic; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA Repair; Ethylnitrosourea; Humans; Phosphorylation; Protein Kinases; Signal Transduction

2014
The MDM2-a splice variant of MDM2 alters transformation in vitro and the tumor spectrum in both Arf- and p53-null models of tumorigenesis.
    Molecular cancer research : MCR, 2009, Volume: 7, Issue:6

    Topics: Animals; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Ethylnitrosourea; Female; Fibroblasts; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Germ Cell and Embryonal; Protein Isoforms; Proto-Oncogene Proteins c-mdm2; Tumor Suppressor Protein p53

2009
Phenotypic alteration of bone marrow HSC and microenvironmental association in experimentally induced leukemia.
    Current stem cell research & therapy, 2010, Volume: 5, Issue:4

    Topics: Animals; Antigens, Ly; Bone Marrow; Cell Transformation, Neoplastic; Cells, Cultured; Disease Progression; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Hyaluronan Receptors; Immunophenotyping; Leukemia; Membrane Proteins; Mice; Neoplastic Stem Cells; Proto-Oncogene Proteins c-kit; Receptors, CXCR4; Tumor Microenvironment

2010
5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.
    International journal of cancer, 2011, May-01, Volume: 128, Issue:9

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Blotting, Western; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Fluorescent Antibody Technique; Glioma; Immunohistochemistry; Neoplasm Staging; Phosphorylation; Rats; Rats, Sprague-Dawley

2011
Immunological profile of arsenic toxicity: a hint towards arsenic-induced carcinogenesis.
    Asian Pacific journal of cancer prevention : APJCP, 2010, Volume: 11, Issue:2

    Topics: Alkylating Agents; Animals; Apoptosis; Arsenic; Caspases; Cell Transformation, Neoplastic; Cytokines; Ethylnitrosourea; Female; Humans; Male; Mice; Neoplasms, Experimental; Tissue Distribution

2010
Sex-biased suppression of chemically induced neural carcinogenesis in congenic BDIX.BDIV-Mss4a rats.
    Physiological genomics, 2011, May-01, Volume: 43, Issue:10

    Topics: Animals; Animals, Congenic; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Genetic Loci; Genome-Wide Association Study; Guanine Nucleotide Exchange Factors; Incidence; Male; Nerve Sheath Neoplasms; Rats; Rats, Transgenic; Sex Characteristics; Survival Analysis

2011
Clonal structure of carcinogen-induced intestinal tumors in mice.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:6

    Topics: Adenomatous Polyposis Coli; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chimerism; Clone Cells; Ethylnitrosourea; Female; Genes, APC; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mutation; Proteins; RNA, Untranslated

2011
Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis.
    International journal of cancer, 2013, Jan-15, Volume: 132, Issue:2

    Topics: Amino Acid Sequence; Animals; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Cell Transformation, Neoplastic; DNA Mutational Analysis; Ethylnitrosourea; Female; Homeodomain Proteins; Ikaros Transcription Factor; Loss of Heterozygosity; Lymphoma, T-Cell; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Point Mutation; Proto-Oncogene Proteins p21(ras); Receptor, Notch1; Transcription Factor HES-1; Transcription, Genetic; Tumor Suppressor Protein p53; X-Rays

2013
Genome-wide allelotyping of a new in vitro model system reveals early events in breast cancer progression.
    Cancer research, 2002, Oct-15, Volume: 62, Issue:20

    Topics: Alleles; Breast; Breast Neoplasms; Cell Adhesion; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Disease Progression; Epithelial Cells; Ethylnitrosourea; Gene Deletion; Genes, p16; Genes, p53; Humans; Loss of Heterozygosity; Telomerase; Telomere

2002
Loss of GFAP expression in high-grade astrocytomas does not contribute to tumor development or progression.
    Oncogene, 2003, May-29, Volume: 22, Issue:22

    Topics: Animals; Astrocytoma; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Mice; Rats; Rats, Nude

2003
Ethylnitrosourea induces neural progenitor cell apoptosis after S-phase accumulation in a p53-dependent manner.
    Neurobiology of disease, 2005, Volume: 18, Issue:1

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Carcinogens; Cell Cycle; Cell Transformation, Neoplastic; Disease Models, Animal; DNA Replication; Ethylnitrosourea; Female; G2 Phase; Male; Mice; Mice, Knockout; Neurons; Rats; Rats, Inbred F344; S Phase; Stem Cells; Tumor Suppressor Protein p53

2005
Gender-specific polygenic control of ethylnitrosourea-induced oncogenesis in the rat peripheral nervous system.
    International journal of cancer, 2006, Jan-01, Volume: 118, Issue:1

    Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Chromosome Mapping; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Male; Multifactorial Inheritance; Neurilemmoma; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred Strains; Sex Factors

2006
The ETS factor TEL2 is a hematopoietic oncoprotein.
    Blood, 2006, Feb-01, Volume: 107, Issue:3

    Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Transplantation; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; ETS Translocation Variant 6 Protein; Female; Gene Expression; Hematopoiesis; HL-60 Cells; Humans; Lymphoma, T-Cell; Male; Mice; Proto-Oncogene Proteins c-ets; Repressor Proteins; Transcription Factors; Translocation, Genetic; U937 Cells

2006
Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-25, Volume: 26, Issue:4

    Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Count; Cell Division; Cell Transformation, Neoplastic; Cerebral Ventricles; DNA Damage; Ethylnitrosourea; Female; Gene Expression Regulation; Genes, p53; Genetic Vectors; Glioblastoma; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multipotent Stem Cells; Neoplasms, Radiation-Induced; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Time Factors; Tumor Suppressor Protein p53

2006
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2005, Volume: 91, Issue:12

    Topics: Alkylating Agents; Animals; Cell Transformation, Neoplastic; Diethylnitrosamine; Ethylnitrosourea; Female; Hypnotics and Sedatives; Leukemia; Lung Neoplasms; Male; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Phenobarbital; Thyroxine

2005
The interaction mode of premalignant Schwann and immune effector cells during chemically induced carcinogenesis in the rat peripheral nervous system is strongly influenced by genetic background.
    Cancer research, 2006, May-01, Volume: 66, Issue:9

    Topics: Animals; Antibodies; CD18 Antigens; Cell Communication; Cell Transformation, Neoplastic; Cranial Nerve Neoplasms; Ethylnitrosourea; Immunohistochemistry; Leukocytes; Macrophages; Neurilemmoma; Precancerous Conditions; Rats; Rats, Inbred Strains; Schwann Cells; T-Lymphocytes, Cytotoxic; Trigeminal Nerve

2006
Electron-microscopic analysis of nephroblastomas induced transplacentally in the IIIVO/J rabbit by a single dose of N-ethylnitrosourea.
    The American journal of pathology, 1984, Volume: 117, Issue:2

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Disease Models, Animal; Ethylnitrosourea; Female; Kidney Glomerulus; Kidney Neoplasms; Kidney Tubules; Mesenchymoma; Nitrosourea Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Wilms Tumor

1984
[In vitro malignant transformation of fetal brain cells exposed in utero to ethylnitrosourea--serological analysis of cell surface antigens of transformed cells (author's transl)].
    Neurologia medico-chirurgica, 1981, Volume: 21, Issue:2

    Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Brain Neoplasms; Cell Transformation, Neoplastic; Epitopes; Ethylnitrosourea; Female; Fetus; Neoplasms, Experimental; Nitrosourea Compounds; Rats

1981
Histologic characterization of renal tumors (nephroblastomas) induced transplacentally in IIIVO/J and WH/J rabbits by N-ethylnitrosourea.
    The American journal of pathology, 1983, Volume: 113, Issue:1

    Topics: Abdominal Neoplasms; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelium; Ethylnitrosourea; Female; Humans; Kidney Glomerulus; Kidney Neoplasms; Kidney Tubules; Lung Neoplasms; Maternal-Fetal Exchange; Neoplasms, Connective Tissue; Pregnancy; Rabbits; Wilms Tumor

1983
Tissue culture of trigeminal nerves from rats administered transplacentally with ethylnitrosourea.
    Acta medica Okayama, 1983, Volume: 37, Issue:4

    Topics: Aging; Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Microscopy, Electron; Neoplasm Transplantation; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Trigeminal Nerve

1983
Transformation of cultured epithelial cells by ethylnitrosourea. Altered expression of type I procollagen chains.
    Biochimica et biophysica acta, 1984, Mar-23, Volume: 803, Issue:3

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Ethylnitrosourea; Kinetics; Macromolecular Substances; Molecular Weight; Nitrosourea Compounds; Peptides; Procollagen; Rats; Tetradecanoylphorbol Acetate

1984
The effect of nerve growth factor and antibodies to nerve growth factor on ethylnitrosourea-induced neoplastic proliferation in rat trigeminal nerves.
    Veterinary pathology, 1984, Volume: 21, Issue:1

    Topics: Animals; Antibodies; Cell Transformation, Neoplastic; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Male; Mice; Nerve Growth Factors; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Trigeminal Nerve

1984
[Prospects in neuro-oncology].
    Minerva medica, 1984, May-19, Volume: 75, Issue:21

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Blood-Brain Barrier; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Ependymoma; Ethylnitrosourea; Humans; Medical Oncology; Mice; Neoplasms, Experimental; Nerve Tissue; Nervous System Neoplasms; Neurology; Nitrosourea Compounds; Prognosis; Prospective Studies; Rats; Stem Cells

1984
[Effect of tumor promoting agents on the in vitro malignant transformation of the fetal rat brain cells exposed in utero to ethylnitrosourea].
    No to shinkei = Brain and nerve, 1984, Volume: 36, Issue:2

    Topics: Animals; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Fetus; In Vitro Techniques; Maternal-Fetal Exchange; Nitrosourea Compounds; Phenobarbital; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate

1984
Alkylation of the O6 of guanine is only one of many chemical events that may initiate carcinogenesis.
    Cancer investigation, 1984, Volume: 2, Issue:3

    Topics: Alkylating Agents; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; Ethylnitrosourea; Guanine; Methylnitrosourea; Neoplasms, Experimental

1984
Transformation of oligodendroglia: a para- or preneoplastic effect of ethylnitrosourea on mouse brain.
    Acta neuropathologica, 1983, Volume: 59, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Demyelinating Diseases; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mice; Microscopy, Electron; Neuroglia; Nitrosourea Compounds; Oligodendroglia; Pregnancy

1983
In vitro transformation of fetal brain cells from CDF rats exposed in utero to N-ethyl-N-nitrosourea: morphologic and immunologic studies.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:5

    Topics: Animals; Animals, Newborn; Antibody Formation; Brain; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Thymectomy; Transplantation, Isogeneic

1980
Malignant transformation of rat neural cells in culture.
    Annals of the New York Academy of Sciences, 1982, Volume: 381

    Topics: Animals; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Microscopy, Electron, Scanning; Rats

1982
DNA cross-linking and monoadduct repair in nitrosourea-treated human tumour cells.
    Nature, 1980, Dec-25, Volume: 288, Issue:5792

    Topics: Cell Line; Cell Transformation, Neoplastic; Cross-Linking Reagents; DNA Repair; DNA, Neoplasm; Ethylnitrosourea; Humans; Methylation; Mutation; Nitrosourea Compounds; Peptide Hydrolases

1980
Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas.
    Cell, 1982, Volume: 28, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA, Neoplasm; Ethylnitrosourea; Fibroblasts; Fibrosarcoma; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neuroblastoma; Phosphoproteins; Rats; Transfection

1982
Alginate: a reversible semi-solid medium for investigating cell transformation.
    British journal of cancer, 1982, Volume: 46, Issue:6

    Topics: Alginates; Animals; Brain; Cell Line; Cell Separation; Cell Survival; Cell Transformation, Neoplastic; Clone Cells; Culture Media; Ethylnitrosourea; Rats

1982
Correlations between sites of chemical modification of DNA, repair, and carcinogenesis.
    Princess Takamatsu symposia, 1982, Volume: 12

    Topics: Alkylating Agents; Alkylation; Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; DNA Repair; Ethylnitrosourea; Humans; Neoplasms; Nucleic Acid Conformation; Transcription, Genetic

1982
Effect of 12-O-tetradecanoylphorbol-13-acetate on two charateristics of transformation acquired sequentially by ENU-exposed rat brain cells.
    British journal of cancer, 1980, Volume: 42, Issue:5

    Topics: Agar; Animals; Brain; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate

1980
Cell culture systems to study glial transformation.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Animals; Astrocytes; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Ethylnitrosourea; Female; Glioma; Humans; Maternal-Fetal Exchange; Neoplasms, Experimental; Neuroglia; Nitrosourea Compounds; Oligodendroglia; Pregnancy; Rats

1980
Responsiveness of fetal rat brain cells to glia maturation factor during neoplastic transformation in cell culture.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1981, Volume: 89, Issue:5

    Topics: Animals; Brain; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Glia Maturation Factor; Microscopy, Electron, Scanning; Nerve Tissue Proteins; Neuroglia; Pregnancy; Rats; Swine

1981
Different response of ENU-exposed and unexposed rat brain cells to cholera toxin at early passages in culture.
    British journal of cancer, 1981, Volume: 43, Issue:2

    Topics: Animals; Brain; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; Clone Cells; Ethylnitrosourea; Female; Nitrosourea Compounds; Rats; Rats, Inbred Strains

1981
Transformation of type 1 astrocytes with N-ethyl-N-nitrosourea: establishment of an in vitro system and the role of the p53 gene.
    Glia, 1995, Volume: 13, Issue:1

    Topics: Animals; Astrocytes; Brain; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; DNA Damage; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Genes, p53; Glioma; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Rats; Rats, Wistar; RNA, Neoplasm; Tumor Stem Cell Assay; Tumor Suppressor Protein p53

1995
Experimental induction of primitive neuro-ectodermal tumours in rats: a re-appraisement of the ENU-model of neurocarcinogenesis.
    Acta neurochirurgica, 1994, Volume: 131, Issue:3-4

    Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Immunoenzyme Techniques; Male; Microscopy, Electron; Neoplasm Transplantation; Neuroectodermal Tumors, Primitive; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar

1994
Complementary tumor induction in neural grafts exposed to N-ethyl-N-nitrosourea and an activated myc gene.
    Carcinogenesis, 1993, Volume: 14, Issue:8

    Topics: Animals; Base Sequence; Brain; Brain Neoplasms; Brain Tissue Transplantation; Cell Transformation, Neoplastic; Cocarcinogenesis; Ethylnitrosourea; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Male; Maternal-Fetal Exchange; Molecular Sequence Data; Pregnancy; Rats; Rats, Inbred F344; Transfection

1993
Wild type neu transgene counteracts mutant homologue in malignant transformation of rat Schwann cells.
    Oncogene, 1996, Mar-21, Volume: 12, Issue:6

    Topics: Alleles; Animals; Base Sequence; Cell Transformation, Neoplastic; Ethylnitrosourea; Gene Expression Regulation, Developmental; Genes, erbB-2; Homozygote; Molecular Sequence Data; Mutation; Neurilemmoma; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Schwann Cells; Transfection; Transgenes; Trigeminal Nerve

1996
Effects of basic fibroblast growth factor on in vivo cerebral tumorigenesis in rats.
    Neurosurgery, 1997, Volume: 40, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Fibroblast Growth Factor 2; Glioma; Humans; Male; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Recombinant Proteins

1997
gp130RB13-6-positive neural progenitor cells are susceptible to the oncogenic effect of ethylnitrosourea in pre-natal rat brain.
    Neuropathology and applied neurobiology, 1998, Volume: 24, Issue:1

    Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Fetus; Humans; Lysosomal Membrane Proteins; Membrane Glycoproteins; Neoplasms, Nerve Tissue; Neurons; Rats; Rats, Inbred Strains; Stem Cells; Tumor Cells, Cultured

1998
Determinants of carcinogen-induced malignant conversion in rat brain: proliferative properties of neural precursor cell subpopulations analyzed by multi-parameter flow cytometry.
    Journal of neuropathology and experimental neurology, 1998, Volume: 57, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Ethylnitrosourea; Flow Cytometry; In Vitro Techniques; Rats; Rats, Inbred Strains; Stem Cells

1998
Activation of neu by missense point mutation in the transmembrane domain in schwannomas induced in C3H/HeNCr mice by transplacental exposure to N-nitrosoethylurea.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:12

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; DNA Mutational Analysis; DNA, Neoplasm; Ethylnitrosourea; Female; Gene Expression Regulation; Maternal-Fetal Exchange; Membrane Proteins; Mice; Mice, Inbred C3H; Molecular Sequence Data; Neurilemmoma; Placenta; Point Mutation; Polymorphism, Restriction Fragment Length; Pregnancy; Protein Structure, Tertiary; Receptor, ErbB-2; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transfection; Tumor Cells, Cultured

1999
Differences in susceptibility to colonic stem cell somatic mutation in three strains of mice.
    The Journal of pathology, 2001, Volume: 193, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Cell Transformation, Neoplastic; Colon; Ethylnitrosourea; Female; Genetic Predisposition to Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mutagens; Mutation; Species Specificity; Stem Cells

2001
ENU mutagenesis of rat mammary epithelial cells.
    Methods in molecular biology (Clifton, N.J.), 2002, Volume: 188

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA; Epithelial Cells; Ethylnitrosourea; Female; Flow Cytometry; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mutagens; Rats

2002
ENU-induced ovarian cancer.
    Methods in molecular biology (Clifton, N.J.), 2002, Volume: 188

    Topics: Animals; Carcinogens; Cell Culture Techniques; Cell Transformation, Neoplastic; DNA; Ethylnitrosourea; Female; Humans; Karyotyping; Ovarian Neoplasms; Ovary; Rats; Sertoli Cell Tumor

2002
[Long-term cultures of experimental CNS tumours as models in neurooncological research (author's transl)].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1976, Volume: 120, Issue:4

    Topics: Animals; Brain Neoplasms; Bucladesine; Cell Division; Cell Transformation, Neoplastic; Culture Techniques; Ethylnitrosourea; Glioma; Methylnitrosourea; Neoplasms, Experimental; Neurilemmoma; Rats; Rats, Inbred Strains; Time Factors

1976
Phenotypic properties of neoplastic cell lines developed from fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1977, Aug-15, Volume: 89, Issue:3

    Topics: Animals; Brain; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Ectoderm; Ethylnitrosourea; Fetus; In Vitro Techniques; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Nitrosourea Compounds; Phenotype; Rats

1977
Surface structure of fetal rat brain cells during neoplastic transformation in cell culture.
    Journal of the National Cancer Institute, 1978, Volume: 61, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Microscopy, Electron, Scanning; Neoplasms, Experimental; Precancerous Conditions; Pregnancy; Rats; Time Factors

1978
Transmission electron microscopy of fetal rat brain cells during neoplastic transformation in cell culture.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors

1979
Characteristics of BALB/C T cell lymphomas grown as continuous in vitro lines.
    Journal of immunology (Baltimore, Md. : 1950), 1978, Volume: 121, Issue:1

    Topics: Animals; Antigens; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Chromosomes; Ethylnitrosourea; Karyotyping; Lymphoma; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; T-Lymphocytes

1978
[Electronmicroscopic investigations of N. trigeminus of rats during the phase of tumour induction by ethylnitrosourea (author's transl)].
    Archiv fur Geschwulstforschung, 1979, Volume: 49, Issue:7

    Topics: Animals; Cell Transformation, Neoplastic; Ethylnitrosourea; Mitosis; Myelin Sheath; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Schwann Cells; Trigeminal Nerve

1979
Fc gamma receptors receptors on fetal rat brain cells during neoplastic transformation in culture after exposure to ethylnitrosourea in vivo.
    Cancer letters, 1979, Volume: 8, Issue:2

    Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Receptors, Fc

1979
[Experimental brain tumor produced transplacentally by ethylnitrosourea (3). Autoradiographic studies on tumor cell proliferation].
    No to shinkei = Brain and nerve, 1977, Volume: 29, Issue:4

    Topics: Animals; Autoradiography; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; DNA, Neoplasm; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats

1977
Changes in surface morphology associated with ethylnitrosourea-induced malignant transformation of cultured rat brain cells studied by scanning electron microscopy.
    British journal of experimental pathology, 1978, Volume: 59, Issue:5

    Topics: Brain; Cell Line; Cell Membrane; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Ethylnitrosourea; Microvilli; Pseudopodia

1978
[Growth kinetics of transplantable mammary gland tumors in mice].
    Voprosy onkologii, 1975, Volume: 21, Issue:10

    Topics: Adenocarcinoma; Animals; Cell Transformation, Neoplastic; Ethylnitrosourea; Kinetics; Male; Mammary Neoplasms, Experimental; Mathematics; Methylnitrosourea; Mice; Mice, Inbred A; Mice, Inbred C3H; Neoplasm Transplantation; Nitrosourea Compounds; Time Factors

1975
Neoplastic transformation of fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:5

    Topics: Animals; Brain; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Models, Biological; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Time Factors

1975
Mutational activation of H-ras oncogene transformability by alkylnitrosourea-induced DNA damage.
    Mutation research, 1992, Volume: 266, Issue:2

    Topics: 3T3 Cells; Alkylation; Animals; Base Sequence; Cell Transformation, Neoplastic; DNA; DNA Damage; Ethylnitrosourea; Gene Expression Regulation; Genes, ras; Methylnitrosourea; Mice; Molecular Sequence Data; Mutation

1992
DNA damage and repair in gamma-glutamyltranspeptidase-positive and negative hepatocytes in primary culture from carcinogen-treated rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 196, Issue:1

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Rats; Rats, Inbred F344

1991
Early mutation of the neu (erbB-2) gene during ethylnitrosourea-induced oncogenesis in the rat Schwann cell lineage.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Nov-15, Volume: 88, Issue:22

    Topics: Alleles; Animals; Base Sequence; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Ethylnitrosourea; Molecular Sequence Data; Mutagenesis; Neurilemmoma; Polymorphism, Restriction Fragment Length; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Rats, Inbred Strains; Receptor, ErbB-2; Schwann Cells

1991
Repair of O6-ethylguanine in DNA protects rat 208F cells from tumorigenic conversion by N-ethyl-N-nitrosourea.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:24

    Topics: Animals; Carmustine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Clone Cells; DNA; DNA Repair; Ethylnitrosourea; Guanine; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats

1990
Enhanced plasminogen activator production of Syrian hamster embryo cells transformed by chemicals or the c-Ha-ras oncogene: type of plasminogen activators involved and their contribution to the transformed phenotype.
    Carcinogenesis, 1989, Volume: 10, Issue:7

    Topics: Animals; Antibodies; Benzo(a)pyrene; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Enzyme Precursors; Ethylnitrosourea; Genes, ras; Humans; Insulin; Isoflurophate; Mesocricetus; Phenotype; Plasminogen Activators; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

1989
Rat renal mesenchymal tumor as an experimental model for human congenital mesoblastic nephroma: II. Comparative pathology.
    Pediatric pathology, 1989, Volume: 9, Issue:2

    Topics: Adult; Animals; Cell Transformation, Neoplastic; Ethylnitrosourea; Humans; Kidney Neoplasms; Rats; Rats, Inbred Strains; Wilms Tumor

1989
Administration of ethylnitrosourea to neonate hamsters increases growth and frequency of SV40-induced fibrosarcomas.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 192, Issue:1

    Topics: Animals; Animals, Newborn; Antigens, Polyomavirus Transforming; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Ethylnitrosourea; Fibrosarcoma; Mesocricetus; Neoplasm Metastasis; Neoplasm Transplantation; Simian virus 40; Tumor Virus Infections

1989
Acutely transforming retroviruses as carcinogens in mouse embryos.
    IARC scientific publications, 1989, Issue:96

    Topics: Animals; Animals, Newborn; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cocarcinogenesis; Embryo, Mammalian; Ethylnitrosourea; Female; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Sarcoma Viruses, Murine

1989
Cell-specific brain tumour induction in neural transplants: evidence for multistep carcinogenesis in the nervous system.
    IARC scientific publications, 1989, Issue:96

    Topics: Animals; Brain; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Nerve Tissue; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344

1989
A sequential ultrastructural and histoautoradiographic study of early neoplastic lesions in ethylnitrosourea-induced rat glioma.
    Acta pathologica japonica, 1989, Volume: 39, Issue:8

    Topics: Animals; Autoradiography; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Glioma; Hyperplasia; Male; Microscopy, Electron; Neurons; Rats; Rats, Inbred Strains

1989
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.
    Cell, 1986, Jun-06, Volume: 45, Issue:5

    Topics: Alleles; Animals; Cell Line; Cell Transformation, Neoplastic; DNA; Ethylnitrosourea; Gene Expression Regulation; Mice; Mutation; Oncogenes; Protein Conformation; Proto-Oncogene Proteins; Rats; Rats, Inbred Strains; Receptor, ErbB-2; Receptors, Cell Surface

1986
Morphological transformation of immortalized hamster dermal fibroblasts following treatment with simple alkylating carcinogens.
    Carcinogenesis, 1988, Volume: 9, Issue:9

    Topics: Alkylating Agents; Animals; Cell Division; Cell Transformation, Neoplastic; Cricetinae; DNA; DNA Damage; Ethylnitrosourea; Genes, ras; Methylnitrosourea; Mice; Mice, Nude; Neoplasms, Experimental; Sulfuric Acid Esters

1988
An increase in plasminogen activator mRNA occurs at an early stage in ethylnitrosourea-induced transformation of rat brain cells.
    Carcinogenesis, 1986, Volume: 7, Issue:3

    Topics: Animals; Brain; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Gene Expression Regulation; Rats; RNA, Messenger; Time Factors; Tissue Plasminogen Activator

1986
Nerve growth factor modification of the ethylnitrosourea model for multiple schwannomas.
    Annals of the New York Academy of Sciences, 1986, Volume: 486

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cranial Nerve Neoplasms; Ethylnitrosourea; Neoplasm Transplantation; Neoplasms, Multiple Primary; Nerve Growth Factors; Nervous System Neoplasms; Neurilemmoma; Neurofibromatosis 1; Rats; Trigeminal Nerve

1986
Transformation of cultured human fetal gastric fibroblasts with physico-chemical agents.
    Scientia Sinica. Series B, Chemical, biological, agricultural, medical & earth sciences, 1988, Volume: 31, Issue:7

    Topics: Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Ethylnitrosourea; Fetus; Fibroblasts; Mice; Neoplasm Transplantation; Rats; Stomach; Ultraviolet Rays

1988
Epidermal growth factor enhances N-ethyl-N-nitrosourea-induced morphological transformation of Syrian hamster embryo cells.
    Carcinogenesis, 1988, Volume: 9, Issue:4

    Topics: Animals; Benzo(a)pyrene; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Epidermal Growth Factor; Ethylnitrosourea; Mesocricetus

1988
Cocarcinogenicity of saccharin and N-alkylnitrosoureas in cultured human diploid fibroblasts.
    Journal of toxicology and environmental health, 1988, Volume: 24, Issue:3

    Topics: Antigens, Neoplasm; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Ethylnitrosourea; Fibroblasts; Humans; Insulin; Interphase; Methylnitrosourea; Saccharin

1988
In vitro malignant transformation of in vivo ENU-induced rat ovarian Sertoli cell tumor (adenoma).
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:2

    Topics: Adenoma; Animals; Cell Transformation, Neoplastic; Chromosome Aberrations; DNA; Ethylnitrosourea; Female; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Rats; Sertoli Cell Tumor; Species Specificity; Tumor Cells, Cultured

1988
Selective induction by N-nitrosoethylurea of oligodendrogliomas in fetal forebrain transplants.
    Cancer research, 1988, May-15, Volume: 48, Issue:10

    Topics: Animals; Brain; Brain Neoplasms; Cell Differentiation; Cell Transformation, Neoplastic; DNA; Ethylnitrosourea; Female; Fetus; Nerve Tissue; Oligodendroglioma; Rats; Rats, Inbred F344

1988
Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea.
    Molecular and cellular biology, 1986, Volume: 6, Issue:10

    Topics: Animals; Brain; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Genes; Glioma; Maternal-Fetal Exchange; Oncogenes; Platelet-Derived Growth Factor; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Rats

1986
Transformation of C3H10T1/2 cells by N-ethyl-N-nitrosourea occurs as a single, low frequency, mutation-like event.
    Carcinogenesis, 1986, Volume: 7, Issue:8

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Ethylnitrosourea; Mice; Mutation; Proto-Oncogenes

1986
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on the in vitro malignant transformation of fetal rat brain cells exposed in utero to ethylnitrosourea.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Concanavalin A; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplastic Stem Cells; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate

1986
Differentiation markers (S-100, GFAP, NSE and D2) in fetal rat brain cells during malignant transformation in cell culture.
    Journal of neuro-oncology, 1985, Volume: 3, Issue:2

    Topics: Animals; Antigens, Surface; Brain; Brain Chemistry; Brain Neoplasms; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Glial Fibrillary Acidic Protein; Nerve Tissue Proteins; Phosphopyruvate Hydratase; Pregnancy; Rats; Rats, Inbred Strains; S100 Proteins

1985
Prognostic role of cell morphology of animal tumors.
    Toxicologic pathology, 1985, Volume: 13, Issue:2

    Topics: Anaplasia; Animals; Cell Cycle; Cell Transformation, Neoplastic; Dog Diseases; Dogs; Ethylnitrosourea; Glioma; Neoplasms; Nerve Growth Factors; Prognosis; Trigeminal Nerve

1985
Genetic and molecular mechanisms of the in vitro transformation of Syrian hamster embryo cells by the carcinogen N-ethyl-N-nitrosourea. I. Correlation of morphological transformation and enhanced fibrinolytic activity to gene mutation, chromosomal alterat
    Carcinogenesis, 1985, Volume: 6, Issue:11

    Topics: Animals; Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cricetinae; Embryo, Mammalian; Ethylnitrosourea; Female; Fibrinolysis; Mesocricetus; Mutation; Sister Chromatid Exchange

1985
Genetic and molecular mechanisms of the in vitro transformation of Syrian hamster embryo cells by the carcinogen N-ethyl-N-nitrosourea II. Correlation of morphological transformation, enhanced fibrinolytic activity, gene mutations, chromosomal alterations
    Carcinogenesis, 1985, Volume: 6, Issue:11

    Topics: Alkylation; Animals; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Cricetinae; DNA; DNA Repair; Ethylnitrosourea; Female; Fibrinolysis; Mesocricetus; Mutation; Sister Chromatid Exchange

1985