ethylnitrosourea has been researched along with Brain Neoplasms in 271 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 164 (60.52) | 18.7374 |
| 1990's | 58 (21.40) | 18.2507 |
| 2000's | 28 (10.33) | 29.6817 |
| 2010's | 20 (7.38) | 24.3611 |
| 2020's | 1 (0.37) | 2.80 |
| Authors | Studies |
|---|---|
| Carrera-González, MP; Martínez-Martos, JM; Ramírez-Expósito, MJ | 1 |
| Bhattacharya, D; Chaudhuri, S; Datta, A; Faruk Sk Md, O; Ghosh, TK; Hazra, I; Mondal, S; Ronsard, L; Singh, MK | 1 |
| Carrera-González, MP; Martínez-Martos, JM; Mayas, MD; Ramírez-Expósito, MJ | 1 |
| Chang, C; Hsu, YH; Jang, T; Lin, CY; Lin, MH; Recht, L; Siow, TY; Tung, YY | 1 |
| Cartron, PF; Debien, E; Hervouet, E; Menanteau, J; Olivier, C; Pouliquen, D; Staehlin, O; Vallette, FM | 1 |
| Alomran, R; Brown, JM; Chernikova, SB; Jang, T; Klussmann, S; Kruschinski, A; Lartey, F; Liu, SC; Merchant, M; Recht, L; Stafford, J; Zboralski, D; Zöllner, S | 1 |
| Acharya, S; Basu, AK; Bhattacharjee, P; Bhattacharya, D; Chatterjee, S; Chaudhuri, S; Das, T; Ghosh, TK; Kumar, P; Sa, G; Singh, MK | 1 |
| Cohen, HJ; Deng, X; Fu, C; Guo, M; Hao, S; Jang, T; Li, Z; Ling, XB; Liu, R; Merchant, M; Recht, L; Tan, Z; Whitin, JC; Zheng, L | 1 |
| Doi, Y; Kanagawa, M; Matsumoto, H; Maya, Y; Nakata, N; Oka, S; Shirakami, Y; Tanaka, A; Toyama, M | 1 |
| Chen, YW; Chou, CP; Hung, YT; Liou, GG; Pan, HB; Tseng, HH | 1 |
| Bulnes, S; Carrasco, A; García-Blanco, A; Lafuente, JV; Pomposo, I | 1 |
| Huang, YC; Lee, WH; Liu, SC; Liu, SJ; Su, CH; Tseng, YY; Wang, YC; Yang, ST | 1 |
| Bilbao, J; Bulnes, S; Lafuente, JV | 1 |
| Argandoña, EG; Bengoetxea, H; Bulnes, S; Lafuente, JV; Leis, O; Ortuzar, N | 1 |
| Acharya, S; Bhattacharjee, M; Chatterjee, S; Chaudhuri, S; Kumar, P | 1 |
| Doblas, S; Garteiser, P; He, T; Herlea, O; Lupu, F; Saunders, D; Silasi-Mansat, R; Smith, N; Towner, RA; Watanabe, Y | 1 |
| Barth, RF; Chou, TC; Elleaume, H; Grecula, JC; Gupta, N; Hoff, BA; Huo, T; Ross, BD; Rousseau, J; Weldon, M; Yang, W | 1 |
| Calaoagan, JM; Jang, T; Kwon, E; Laderoute, KR; Recht, L; Samuelsson, S | 1 |
| Balenci, L; Barbier, E; Baudier, J; Beaumont, M; Briançon-Marjollet, A; Estève, F; Farion, R; Fernandez, M; Honnorat, J; Rémy, C | 1 |
| Inoue, K; Irie, K; Kodama, Y; Matsuo, S; Takahashi, M; Tamura, K; Yoshida, M | 1 |
| Binh, NH; Hara, A; Hatano, Y; Hirata, A; Kobayashi, K; Kuno, T; Satoh, K; Takamatsu, M; Tomita, H | 1 |
| Cohen, HJ; Jang, T; Lau, K; Merchant, M; Recht, B; Recht, L; Whitin, JC; Yu, TT | 1 |
| Bjerkvig, R; Eliasson, C; Pekny, M; Wilhelmsson, U | 1 |
| Bjerkvig, R; Enger, PO; Ersland, L; Huszthy, PC; Lund-Johansen, M; Lundervold, A; Nordli, H; Standnes, T; Thorsen, F | 1 |
| Jang, T; Litofsky, NS; Recht, LD; Ross, AH; Smith, TW | 1 |
| Chaudhuri, S; Duttagupta, AK; Ghosh, A; Mukherjee, J; Sarkar, S | 1 |
| Zhang, YF; Zhang, ZY | 1 |
| Begum, Z; Bhattacharjee, M; Chaudhuri, S; Dutta, S; Roy, UR; Sarkar, S | 1 |
| Begum, Z; Chaudhuri, S; Gangopaddhyay, SK; Sarkar, S | 1 |
| Begum, Z; Chaudhuri, S; Ghosh, A; Mazumdar, M; Mukherjee, J; Sarkar, P; Sarkar, S | 1 |
| Chaudhuri, S; Ghosh, A; Mukherjee, J; Sarkar, S | 1 |
| Alfke, H; Heverhagen, JT; Kosse, N; Mennel, HD | 1 |
| Doi, K; Katayama, K; Nagata, T; Nakayama, H; Ueno, M; Yamauchi, H | 1 |
| Jang, T; Litofsky, NS; Low, HP; Matuasevic, Z; Recht, LD; Ross, AH; Salmonsen, R; Savarese, TM | 1 |
| Chaudhuri, S; Duttagupta, AK; Ghosh, A; Mazumdar, M; Mukherjee, J; Sarkar, P; Sarkar, S | 1 |
| Chaudhuri, S; Ghosh, A; Mukherjee, J | 1 |
| Casaccia-Bonnefil, P; Garcia-Verdugo, JM; Gil-Perotin, S; Li, J; Marin-Husstege, M; Roussel, MF; Soriano-Navarro, M; Zindy, F | 1 |
| Bui, T; Ho, RJ; Yimam, MA | 1 |
| Fujiwara, O; Ichihara, T; Kawabe, M; Shirai, T; Takahashi, S; Taki, M; Tamano, S; Wake, K; Wang, J; Watanabe, S; Yamanaka, Y | 1 |
| Chang, C; Hsu, YH; Jang, T; Merchant, M; Recht, B; Recht, L; Sathy, B | 1 |
| Debien, E; Gratas, C; Hervouet, E; Homma, T; Le Cabellec, MT; Meflah, K; Menanteau, J; Olivier, C; Pedelaborde, F; Pouliquen, D; Vallette, FM | 1 |
| Chung, MK; Ha, CS; Kim, YB; Myung, SH | 1 |
| Blasberg, RG; Groothuis, DR; Molnar, P | 1 |
| Handa, H; Kieler, J; Oda, Y; Tokuriki, Y | 1 |
| Cravioto, H; Kageyama, N; Kida, Y; Kobayashi, T; Ransohoff, J; Shibuya, N; Yoshida, J | 1 |
| Arita, N; Hayakawa, T; Horibata, K; Mogami, H; Morimoto, K; Ushio, Y; Yoshimine, T | 2 |
| Lantos, PL | 4 |
| Knowles, JF | 1 |
| Kleihues, P; Rajewsky, MF | 1 |
| De Ridder, L; Laerum, OD; Mørk, SJ | 1 |
| Deen, DF; Marton, LJ; Oredsson, SM | 1 |
| Bodell, WJ; Gerosa, MA; Rosenblum, ML; Talcott, RL | 1 |
| Enke, H; Rath, FW | 1 |
| Deen, DF; Tofilon, PJ | 1 |
| Abe, H; Aida, T; Kaneko, S; Tokuda, K; Tsuru, M | 1 |
| Aleksandrov, VA; Anisimov, VN; Bespalov, VG; Khavinson, VKh; Morozov, VG | 1 |
| Blasberg, RG; Fenstermacher, JD; Groothuis, D; Horowitz, M; Kobayashi, T; Molnar, P; Rice, JM | 2 |
| Bertolotto, A; Giordana, MT; Magrassi, ML; Mauro, A; Migheli, A; Schiffer, D | 1 |
| Gi, H; Handa, H; Yamashita, J | 1 |
| Bonnin, JM; Marangos, PJ; Rubinstein, LJ; Vinores, SA | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N; Taomoto, K | 1 |
| Kokunai, T; Matsumoto, S; Tamaki, N | 2 |
| Allen, N; Clendenon, NR; Qavi, HB | 1 |
| Abe, M; Kitamura, K; Nishio, S; Ohta, M | 1 |
| Ikeda, T; Kohno, S; Maeda, H; Matsuo, T; Tashiro, T | 1 |
| Cravioto, H; Ransohoff, J; Yoshida, J | 1 |
| Giordana, MT; Mauro, A; Schiffer, D | 1 |
| Habs, M; Ivankovic, S; Schmähl, D; Zeller, WJ | 1 |
| de Ridder, L; Laerum, OD; Rajewsky, MF | 1 |
| De Bernardo, E | 1 |
| Arita, N; Hayakawa, T; Horibata, K; Mori, T; Ushio, Y; Yoshimine, T | 1 |
| Roscoe, JP | 1 |
| Alvira, MM; Mandybur, TI | 1 |
| Ilsen, HW; Mennel, HD; Petrovici, IN; Szymas, J; Zülch, KJ | 1 |
| Enzan, H; Hara, H; Kutsukake, F; Miyao, M; Moriki, T; Yamane, T | 1 |
| Ito, A; Naito, M; Naito, Y | 3 |
| Hayakawa, T; Kato, A; Mogami, H; Ushio, Y; Yamada, K; Yamada, N | 2 |
| Abe, M | 1 |
| Kalter, H; Ormsby, I; Warkany, J | 1 |
| Alexandrov, VA; Anisimov, VN; Napalkov, NP | 1 |
| Arita, N; Hayakawa, T; Kato, A; Mogami, H; Ushio, Y; Yamada, K | 2 |
| Maat, B; van Bekkum, DW; van Zwieten, MJ; Vecht, CJ | 1 |
| Cohadon, F | 1 |
| Bruno, F; Giordana, MT; Mauro, A; Paoletti, P; Pezzotta, S; Racagni, G; Schiffer, D | 1 |
| Conley, FK | 2 |
| Fujiwara, H | 1 |
| Yun, K | 1 |
| Perez-Polo, JR; Vinores, SA | 1 |
| Dooling, EC; Richardson, EP | 1 |
| Berger, MS; Blank, A; Bobola, MS; Silber, JR | 1 |
| Oya, S; Vaquero, J; Zurita, M | 2 |
| Aas, AT; Blennow, C; Brun, A; Salford, LG; Strömblad, S | 1 |
| Arias, A; Buján, J; Coca, S; García, N; Morales, C; Oya, S; Vaquero, J; Zurita, M | 1 |
| Handa, J; Matsumura, K; Nakasu, S; Nioka, H | 1 |
| Coca, S; Oya, S; Vaquero, J; Zurita, M | 3 |
| Shibutani, M | 1 |
| Cabrera, MM; Morales, C; Oya, S; Vaquero, J; Zurita, M | 1 |
| Alcaraz-Zubeldia, MM; Barroso-Moguel, R; Galván-Arzate, S; Méndez-Armenta, M; Ríos, C; Villeda-Hernández, J | 1 |
| Blass-Kampmann, S; Kindler-Röhrborn, A; Lennartz, K; Liepelt, U; Minwegen, R; Rajewsky, MF | 1 |
| Hall, DG; Stoica, G | 1 |
| Morales, C; Oya, S; Vaquero, J; Zurita, M | 1 |
| Izumu, I; Kowada, M; Mineura, K; Watanabe, K | 1 |
| Broglia, E; Perin, A; Sessa, A; Terreni, MR | 2 |
| Arita, N; Hayakawa, T; Higuchi, M; Hiraga, S; Ohnishi, T; Taki, T; Yamamoto, H | 1 |
| Brüstle, O; Höll, T; Kleihues, P; Petersen, I; Plate, KH; Radner, H; Wiestler, OD | 1 |
| Alexandrov, VA; Anisimov, VN; Bespalov, VG; Khavinson, VKh; Morozov, VG | 1 |
| Alexandrov, VA; Bespalov, VG; Petrov, AS; Troyan, DN | 1 |
| Aizawa, S; Ishikawa, T; Nakatsuru, Y; Oda, H; Shimizu, S; Tsurutani, N; Zhang, S | 1 |
| Cervós-Navarro, J; Cruz-Sánchez, FF; Figols, J; Kroh, H | 1 |
| Bederson, JB; Germano, IM; Segal, DH | 1 |
| Aoyagi, K; Chen, CJ; Enkawa, T; Furuhama, K; Hirota, T; Ozaki, Y; Satoh, H; Sekiguchi, F; Yamada, K | 1 |
| Hiasa, Y; Konishi, N; Nakamura, M; Sakaki, T; Tsunoda, S; Tsuzuki, T; Yabuno, T | 1 |
| Bilzer, T; Blass-Kampmann, S; Rajewsky, MF | 1 |
| Iki, K; Kido, A; Kobitsu, K; Konishi, Y; Nakae, D; Nakamura, M; Sakaki, T; Sakitani, H; Takahama, M; Tsujiuchi, T; Tsutsumi, M | 1 |
| Geiger, M; Kindler-Röhrborn, A; Lennartz, K; Rajewsky, MF | 1 |
| Inokuchi, T; Kaidoh, T; Shigemori, M; Yoshimura, F | 1 |
| Blaivas, M; Kish, P; Muraszko, KM; Ross, DA; Strawderman, M | 1 |
| Bartels, HJ; Kappler, R; Kraus, A; Kühne, C; Mennel, HD; Piontek, G; Schlegel, J | 1 |
| Boncinelli, E; Canal, N; Feltri, ML; Nemni, R; Pardini, CL; Previtali, SC; Quattrini, A; Wrabetz, L | 1 |
| Calloni, A; Perin, A; Rabellotti, E; Sessa, A; Tunici, P | 1 |
| Adey, WR; Byus, CV; Cain, CD; Haggren, W; Higgins, RJ; Jones, RA; Kean, CJ; Kuster, N; MacMurray, A; Phillips, JL; Stagg, RB; Zimmerman, G | 1 |
| Barnett, L; Lewis, S; Malling, HV; Newbold, RR; Weaver, RP | 1 |
| Bodell, WJ | 1 |
| Groothuis, DR; Lapin, GD; Molnar, P; Schlageter, KE | 1 |
| Buslei, R; Kindler-Röhrborn, A; Koelsch, BU; Rajewsky, MF; Wiestler, OD; Zabel, S | 1 |
| Désy, M; Devaux, C; Franco, E; Gaboury, L; Mandeville, R; Mercier, G; Paris-Nadon, L; Rocheleau, N; Sidrac-Ghali, S | 1 |
| Adey, WR; Byus, CV; Cain, CD; Higgins, RJ; Jones, RA; Kean, CJ; Kuster, N; MacMurray, A; Stagg, RB; Zimmerman, G | 1 |
| Hara, A; Mori, H; Sakai, N; Shinoda, J; Takenaka, K; Yano, H; Yoshimi, N | 1 |
| Simmens, SJ; Zook, BC | 1 |
| Blaivas, M; Kish, PE; McMahon, G; Muraszko, KM; Ross, BD; Ross, DA; Strawderman, M | 1 |
| D'Sa, C; Klocke, BJ; Leonard, JR; Roth, KA | 1 |
| Rembao, D; Reyes, S; Sotelo, J | 1 |
| Chang, MJ; Koestner, A; Webb, TE | 1 |
| Allen, N; Coleman, MT | 1 |
| Matsumoto, S; Tanaka, M | 1 |
| Matsumoto, S; Tamaki, N; Taomoto, K | 1 |
| Fujiwara, K; Matsumoto, S; Tamaki, N; Taomoto, K | 1 |
| Fujiwara, K; Matsumoto, S; Tanaka, M | 1 |
| Hadjiolov, D; Venkov, L | 1 |
| Kampmann, H | 1 |
| Giordana, MT; Paoletti, P; Pezzotta, S; Schiffer, D | 2 |
| Falk, HL; Hudson, PM; Jurgelski, W; Kotin, P | 1 |
| Kay, JM; Laidler, P | 1 |
| Thust, R | 1 |
| Swenberg, JA | 1 |
| Pfeiffer, SE; Ramadan, MA; Wechsler, W | 1 |
| Claisse, PJ; Lantos, PL; Roscoe, JP | 2 |
| Falk, HL; Hudson, P; Jurgelski, W | 1 |
| Cravioto, H; Yoshida, J | 1 |
| Claisse, PJ; Roscoe, JP | 2 |
| Haugen, A; Laerum, OD | 2 |
| Lehnguth, C; Osske, G; Schneider, J; Warzok, R | 1 |
| Elrick, WL; Qvist, R; Randell, VB; Toh, BH | 1 |
| Hayakawa, T; Mogami, H; Mori, T; Morimoto, K; Ushio, Y; Yoshimine, T | 1 |
| Rice, JM; Vesselinovitch, SD; Wechsler, W | 1 |
| Lantos, PL; Pilkington, GJ | 3 |
| Hellström, I; Hellström, KE; Spence, AM; Sullivan, K; Van Belle, G; Wahlström, T | 1 |
| Ivankovic, S | 1 |
| Ambers, LS; Chou, KH; Jungalwala, FB | 1 |
| Bruno, F; Giordana, MT; Paoletti, P; Pezzotta, S; Racagni, G; Schiffer, D | 1 |
| Matsumoto, M | 1 |
| Maat, B; van Bekkum, DW; van Zwieten, MJ; Vecht, C | 1 |
| Haugen, A; Matre, R | 1 |
| Taomoto, K | 2 |
| Kageyama, N; Kameyama, Y; Kobayashi, T; Umemura, S; Yoshida, J | 1 |
| Giordana, MT; Lechner, C; Paoletti, P; Pezzotta, S; Schiffer, D | 1 |
| Hince, TA; Roscoe, JP | 1 |
| Aleksandrov, VA; Schreiber, D | 1 |
| Gerlach, H; Peschel, B; Rath, FW; Schreiber, D; Wessel, H | 1 |
| Golub', NI; Shabad, LM | 1 |
| Habs, M; Schmähl, D | 1 |
| Felicetti, D; Rath, FW | 1 |
| Pozharisskiĭ, KM | 1 |
| Alexandrov, VA | 1 |
| Bosch, DA | 1 |
| Koka, M; Mihailovich, N; Rao, KV; Rice, JM; Vesselinovitch, SD | 1 |
| Herschman, HR; Stahn, R; Uki, J; West, GJ | 1 |
| Jones, EL; Searle, CE | 1 |
| Cox, DJ; Lantos, PL | 1 |
| Abe, H; Ito, T; Kobayashi, N; Tashiro, K; Tsuru, M | 1 |
| Fields, KL; Gosling, C; Megson, M; Stern, PL | 1 |
| Norrell, H; Slagel, DE | 1 |
| Agradi, E; Paoletti, P; Pezzotta, S | 1 |
| Herschman, H; Rose, S; Sanborn, S; Stahn, R; West, G | 1 |
| Zeller, WJ | 1 |
| Denlinger, RH; Koestner, A | 1 |
| Laerum, OD; Rajewsky, MF | 1 |
| Rustia, M | 1 |
| Adam, WE; Kampmann, H; Sinn, H | 1 |
| Allen, N; Clendenon, NR; Goldman, H; Gordon, WA | 1 |
| Lantos, PL; Roscoe, JP; Skidmore, CJ | 1 |
| Conley, FK; Herman, MM; Rubinstein, LJ; Spence, AM | 1 |
| Aguzzi, A; Basilico, C; Brüstle, O; Kleihues, P; Talarico, D; Wiestler, OD | 1 |
| Tokuda, K | 1 |
| Giordana, MT; Migheli, A; Mocellini, C; Schiffer, D; Villare, F | 1 |
| Arias, A; Coca, S; Morales, C; Moreno, M; Oya, S; Vaquero, J; Zurita, M | 2 |
| Ikeda, T; Iwasaki, K; Matsuo, T; Shimokawa, I; Takeshima, F | 1 |
| Arias, A; Coca, S; Morales, C; Oya, S; Vaquero, J; Zurita, M | 1 |
| Amin, S; Hecht, SS; Iatropoulos, MJ; Lasker, SE; Misra, B; Williams, GM; Zang, E | 1 |
| Kang, H; Maekawa, A; Nagase, S; Shumiya, S; Usuki, S | 1 |
| Dayan, A; Purves, D | 1 |
| Galloway, PG; Likavec, MJ; Perry, G | 1 |
| Mennel, HD; Plate, KH; Rüschoff, J | 1 |
| Aruffo, C; Iglesias, JR; Kroh, H; Matyja, A | 1 |
| Hasgekar, N; Lalitharao, VS; Murugesan, S; Patel, MC; Ramanathan, P; Samuel, AM | 1 |
| Dreyhaupt, T; Mennel, HD | 1 |
| Nice, L; Schmahl, W; Stammberger, I | 1 |
| Leierseder-Bauer, M; Luz, A; Neuhäuser-Klaus, A; Schmahl, W | 1 |
| Huang, Y; Tao, H; Yang, G | 1 |
| Giaccone, G; Giordana, MT; Mauro, A; Migheli, A; Pezzotta, S; Schiffer, D | 1 |
| Bilzer, T; Reifenberger, G; Seitz, RJ; Wechsler, W | 1 |
| Fukushima, M; Jinnouchi, T; Mori, K; Shibata, S | 1 |
| Donovan, PJ; Perantoni, AO; Rehm, S; Rice, JM | 1 |
| Arany, I; Fox, M; Kertai, P; Kinsella, AR; Rády, P | 1 |
| Abe, S; Hinokuma, K; Kumanishi, T; Nishiyama, A; Yamada, M; Yoshida, Y | 1 |
| Neame, SJ; Roscoe, JP | 1 |
| Kroh, H; Weinrauder, H | 1 |
| Palencia, G; Perez, R; Rosas, N; Sotelo, J | 1 |
| Aguzzi, A; Burger, PC; Kleihues, P; Shibata, T | 2 |
| Ikeda, T; Iwasaki, K; Mashimoto, H; Matsuo, T; Shimokawa, I | 1 |
| Lantos, PL; Martin, JM; Pilkington, GJ | 1 |
| Kriegel, H; Schmahl, W | 2 |
| Motoi, M; Ogawa, K; Yoshino, T | 2 |
| D'Incalci, M; Day, R; Erickson, LC; Kohn, KW; Kornblith, PL; Laurent, G; Sariban, E; Smith, BH; Zlotogorski, C | 1 |
| Greenwood, J; Lantos, PL; Luthert, PJ; Pratt, OE | 1 |
| Mennel, HD | 1 |
| Dingeldein, E; Jansen, J; Mandel, T; Mennel, HD; Rama, B | 1 |
| Abe, M; Amano, K; Hatanaka, H; Kitamura, K; Ohta, M; Tateishi, J | 1 |
| Huh, NH; Rajewsky, MF | 1 |
| Fukui, M; Inoue, T; Iwaki, T; Nishio, S; Takeshita, I; Tashima, T | 1 |
| Hayakawa, T; Maruno, M; Mogami, H; Nakajima, Y; Ushio, Y; Yoshimine, T | 1 |
| Altena, B; Lens, PF; Nusse, R | 1 |
| Dean, PN; Deen, DF; Gray, JW; Linfoot, PA; Marton, LJ | 1 |
| Kokunai, T; Korosue, K; Matsumoto, S; Tamaki, N | 1 |
| Hellwig, D; Mennel, HD; Simon, H | 1 |
| Aida, T; Bodell, WJ; Rasmussen, J | 1 |
| Aoyama, H; Fujioka, Y; Ito, A; Naito, M | 1 |
| Yoshino, T | 1 |
| Holzgraefe, M; Mennel, HD; Rama, B; Spoerri, O | 1 |
| Koestner, A | 1 |
| Kovatch, RM; Lijinsky, W; Singer, GM | 1 |
| Furuta, K; Hayashi, Y; Maekawa, A; Matsuoka, C; Mitsumori, K; Ogiu, T; Onodera, H; Tanigawa, H | 1 |
| Bock, E; Haglid, K; Haugen, A; Laerum, OD; Mørk, SJ; Rosengren, L | 1 |
| Bitoh, S; Hayakawa, T; Jamshid, J; Maruno, M; Mogami, H; Ushio, Y; Yoshimine, T | 1 |
| Abe, H; Allen, N; Clendenon, NR; Swenberg, JA | 1 |
9 review(s) available for ethylnitrosourea and Brain Neoplasms
| Article | Year |
|---|---|
Chemical neuro-oncogenesis: role of structural DNA modifications, DNA repair and neural target cell population.
Topics: Alkylating Agents; Alkylation; Animals; Brain; Brain Neoplasms; Carcinogens; Cell Count; DNA; DNA Repair; Ethylnitrosourea; Female; Fetal Diseases; Humans; Methylnitrosourea; Pregnancy | 1984 |
The transformation process.
Topics: Animals; Brain; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Humans; Hyperplasia; Karyotyping; Neoplasm Invasiveness; Neoplasm Staging; Nerve Tissue Proteins; Plasminogen Activators | 1984 |
Tumor cell resistance.
Topics: Alkylation; Animals; Antineoplastic Agents; Biotransformation; Brain; Brain Neoplasms; Catalase; Cell Survival; Dihydrolipoamide Dehydrogenase; DNA; DNA Repair; Drug Resistance; Ethylnitrosourea; Glutathione Peroxidase; Humans; NADPH-Ferrihemoprotein Reductase; Superoxide Dismutase | 1984 |
In-vivo-in-vitro analysis of ethylnitrosourea-induced brain carcinogenesis in the rat.
Topics: Animals; Brain Neoplasms; Cell Survival; Cells, Cultured; Clone Cells; Ethylnitrosourea; Fibrinolysis; Neoplasms, Experimental; Nitrosourea Compounds; Plasminogen Activators; Rats; Time Factors | 1980 |
Chemical- and virus-induced brain tumors.
Topics: Adenoviridae; Alkylation; Alpharetrovirus; Animals; Brain Neoplasms; Carcinogens; Disease Models, Animal; DNA, Neoplasm; Ethylnitrosourea; Humans; Methylnitrosourea; Neoplasms, Experimental; Oncogenic Viruses; Papillomaviridae; Polycyclic Compounds; Polyomaviridae; Retroviridae; Tumor Virus Infections | 1977 |
Tissue differentiation and susceptibility to embryonal tumor induction by ethylnitrosourea in the opossum.
Topics: Age Factors; Animals; Animals, Newborn; Brain Neoplasms; Ethylnitrosourea; Eye Neoplasms; Female; Jaw Neoplasms; Kidney Neoplasms; Male; Neoplasms, Experimental; Neoplasms, Germ Cell and Embryonal; Nitrosourea Compounds; Odontogenic Tumors; Opossums | 1979 |
Transplacental and neonatal induction of neurogenic tumors in mice: comparison with related species and with human pediatric neoplasms.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Child; Ethylnitrosourea; Female; Humans; Male; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Species Specificity | 1979 |
[Successes of experimental oncology and problems of the study of the morphogenesis of tumors].
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Aflatoxins; Animals; Azoxymethane; Benzopyrenes; Brain Neoplasms; Carcinogens; Cricetinae; Dimethylhydrazines; Dogs; Esophageal Neoplasms; Ethionine; Ethylnitrosourea; Female; Hematopoietic System; Intestinal Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosamines; Nitroso Compounds; Nitrosoguanidines; o-Aminoazotoluene; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms | 1975 |
Development of nitrosourea-induced brain tumours--with a special note on changes occurring during latency.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasm Invasiveness; Neoplastic Stem Cells; Phenotype; Precancerous Conditions; Pregnancy; Time Factors | 1986 |
262 other study(ies) available for ethylnitrosourea and Brain Neoplasms
| Article | Year |
|---|---|
Sex differences exist in brain renin-angiotensin system-regulating aminopeptidase activities in transplacental ethyl-nitrosourea-induced gliomas.
Topics: Aminopeptidases; Animals; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Male; Rats, Wistar; Renin-Angiotensin System; Sex Characteristics | 2021 |
T11TS immunotherapy repairs PI3K-AKT signaling in T-cells: Clues toward enhanced T-cell survival in rat glioma model.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Brain Neoplasms; CD28 Antigens; CD58 Antigens; Cell Survival; Ethylnitrosourea; Female; Glioma; Immunotherapy; Male; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats; Signal Transduction; T-Lymphocytes; Tumor Escape | 2018 |
Gender Differences in the Antioxidant Response to Oxidative Stress in Experimental Brain Tumors.
Topics: Alkylating Agents; Animals; Antioxidants; Biomarkers; Brain Neoplasms; Ethylnitrosourea; Female; Glutathione; Lipid Peroxidation; Male; Oxidative Stress; Rats, Wistar; Sex Factors; Superoxide Dismutase | 2019 |
Visualization of rodent brain tumor angiogenesis and effects of antiangiogenic treatment using 3D ΔR2-μMRA.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Corpus Striatum; Ethylnitrosourea; Female; Glioma; Imaging, Three-Dimensional; Immunoenzyme Techniques; Magnetic Resonance Angiography; Neoplasm Transplantation; Neovascularization, Pathologic; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2013 |
Antioxidants delay clinical signs and systemic effects of ENU induced brain tumors in rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Brain Neoplasms; Cell Proliferation; Ethylnitrosourea; Female; Glioma; Insulin-Like Growth Factor Binding Protein 5; Ki-67 Antigen; Male; Rats; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Sodium Selenite; Superoxide Dismutase; Zinc | 2013 |
Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Chemokine CXCL12; Ethylnitrosourea; Human Umbilical Vein Endothelial Cells; Humans; Magnetic Resonance Imaging; Mice; Neoplasm Recurrence, Local; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, CXCR; Receptors, CXCR4; Survival Rate; X-Ray Therapy | 2014 |
The novel immunotherapeutic molecule T11TS modulates glioma-induced changes of key components of the immunological synapse in favor of T cell activation and glioma abrogation.
Topics: Animals; Apoptosis; Brain Neoplasms; CD2 Antigens; CD58 Antigens; Ethylnitrosourea; Female; Flow Cytometry; Fluorescent Antibody Technique; Glioma; Glycopeptides; Immunological Synapses; Lymphocyte Activation; Male; Mice; Mutagens; Signal Transduction; T-Lymphocytes | 2014 |
Cerebrospinal fluid protein dynamic driver network: At the crossroads of brain tumorigenesis.
Topics: Animals; Brain; Brain Neoplasms; Carcinogenesis; Cerebrospinal Fluid Proteins; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Glioma; Humans; Neoplasms, Experimental; Proteome; Rats | 2015 |
Evaluation of trans-1-amino-3-18F-fluorocyclobutanecarboxylic acid accumulation in low-grade glioma in chemically induced rat models: PET and autoradiography compared with morphological images and histopathological findings.
Topics: Alkylating Agents; Animals; Autoradiography; Blood-Brain Barrier; Brain Neoplasms; Carboxylic Acids; Cyclobutanes; Ethylnitrosourea; Female; Fluorine Radioisotopes; Glioma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Neoplasm Grading; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Inbred F344; Tissue Distribution | 2015 |
Specific detection of CD133-positive tumor cells with iron oxide nanoparticles labeling using noninvasive molecular magnetic resonance imaging.
Topics: AC133 Antigen; Animals; Antibodies; Antigens, CD; Brain Neoplasms; Cell Death; Dextrans; Ethylnitrosourea; Glycoproteins; HT29 Cells; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Molecular Imaging; Peptides; Protein Binding; Rats; Staining and Labeling; Xenograft Model Antitumor Assays | 2015 |
Nestin+cells forming spheroids aggregates resembling tumorspheres in experimental ENU-induced gliomas.
Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Glioma; Immunohistochemistry; Neoplastic Stem Cells; Nestin; Rats; Rats, Sprague-Dawley | 2016 |
Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drug-loaded nanofibrous membranes.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bibenzyls; Brain; Brain Neoplasms; Camptothecin; Cisplatin; Disease Models, Animal; Drug Delivery Systems; Ethylnitrosourea; Glioblastoma; Glioma; Humans; Irinotecan; Lactic Acid; Male; Nanofibers; Neurosurgical Procedures; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Tumor Burden | 2016 |
Microvascular adaptive changes in experimental endogenous brain gliomas.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Carcinogens; Ethylnitrosourea; Glioma; Immunohistochemistry; Microvessels; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley | 2009 |
The role of eNOS in vascular permeability in ENU-induced gliomas.
Topics: Animals; Autoantigens; Brain Neoplasms; Capillary Permeability; Disease Models, Animal; Ethylnitrosourea; Gadolinium; Glioma; Glucose Transporter Type 1; Nitric Oxide Synthase Type III; Pentetic Acid; Plant Lectins; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A | 2010 |
Induction of G1 arrest in glioma cells by T11TS is associated with upregulation of Cip1/Kip1 and concurrent downregulation of cyclin D (1 and 3).
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Brain Neoplasms; Cyclin D; Cyclin D1; Cyclin D3; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Down-Regulation; Erythrocyte Membrane; Ethylnitrosourea; Female; Flow Cytometry; G1 Phase; Glioma; Glycoproteins; Male; Rats; Rats, Inbred Strains; Sheep; Tumor Cells, Cultured; Up-Regulation | 2010 |
In vivo detection of inducible nitric oxide synthase in rodent gliomas.
Topics: Albumins; Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Tumor; Ethylnitrosourea; Female; Fluorescence; Gadolinium DTPA; Glioma; Immunohistochemistry; Male; Microscopy, Electron, Transmission; Molecular Probe Techniques; Neoplasm Transplantation; Nitric Oxide Synthase Type II; Pregnancy; Rats; Rats, Inbred F344 | 2010 |
Convection enhanced delivery of carboplatin in combination with radiotherapy for the treatment of brain tumors.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Brain Neoplasms; Carboplatin; Combined Modality Therapy; Convection; Disease Models, Animal; Drug Delivery Systems; Ethylnitrosourea; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Radiation Dosage; Rats; Rats, Inbred F344; Survival Rate; Tissue Distribution; X-Ray Therapy | 2011 |
5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Blotting, Western; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Fluorescent Antibody Technique; Glioma; Immunohistochemistry; Neoplasm Staging; Phosphorylation; Rats; Rats, Sprague-Dawley | 2011 |
NG2-expressing glial precursor cells are a new potential oligodendroglioma cell initiating population in N-ethyl-N-nitrosourea-induced gliomagenesis.
Topics: Animals; Antigens; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Ethylnitrosourea; Neoplastic Stem Cells; Oligodendroglioma; Proteoglycans; ras GTPase-Activating Proteins; Rats; Rats, Sprague-Dawley | 2010 |
Development of an early induction model of medulloblastoma in Ptch1 heterozygous mice initiated with N-ethyl-N-nitrosourea.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Ethylnitrosourea; Heterozygote; Medulloblastoma; Mice; Mice, Knockout; Patched Receptors; Patched-1 Receptor; Purkinje Cells; Receptors, Cell Surface | 2012 |
Galectin-3 in preneoplastic lesions of glioma.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Calcium-Binding Proteins; Cell Proliferation; Ethylnitrosourea; Female; Galectin 3; Glial Fibrillary Acidic Protein; Glioma; Humans; Microfilament Proteins; Precancerous Conditions; Rats; Rats, Wistar | 2013 |
Alterations in cerebrospinal fluid proteins in a presymptomatic primary glioma model.
Topics: Animals; Biomarkers; Brain; Brain Neoplasms; Cerebrospinal Fluid Proteins; Disease Models, Animal; Ethylnitrosourea; Gene Expression Regulation, Neoplastic; Glioma; Glutathione; Intermediate Filament Proteins; Nerve Tissue Proteins; Nestin; Proteome; Proteomics; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Loss of GFAP expression in high-grade astrocytomas does not contribute to tumor development or progression.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Mice; Rats; Rats, Nude | 2003 |
Imaging of experimental rat gliomas using a clinical MR scanner.
Topics: Animals; Brain Neoplasms; Collagen; Disease Models, Animal; Endostatins; Ethylnitrosourea; Female; Glioma; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neoplasms, Experimental; Peptide Fragments; Rats; Transfection; Tumor Cells, Cultured | 2003 |
Aberrant nestin expression during ethylnitrosourea-(ENU)-induced neurocarcinogenesis.
Topics: Animals; Biomarkers, Tumor; Brain Injuries; Brain Neoplasms; Carcinogens; Cell Lineage; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Gliosis; Immunohistochemistry; Intermediate Filament Proteins; Microscopy, Confocal; Nerve Tissue Proteins; Nestin; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2004 |
Immunotherapeutic effects of T11TS/S-LFA3 against nitrosocompound mediated neural genotoxicity.
Topics: Adjuvants, Immunologic; Age Factors; Animals; Apoptosis; Brain; Brain Neoplasms; CD2 Antigens; CD58 Antigens; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Ethylnitrosourea; Female; Lymphocytes; Male; Mutagens; Phagocytosis; Rats; Rosette Formation; Sheep; Spleen | 2004 |
[p16 protein expression in the transplacental induced brain tumor in rat].
Topics: Animals; Brain; Brain Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Male; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Differential regulation of the protein tyrosine kinase activity following interleukin-2 (IL-2), interferron gamma (IFN-gamma) and SRBC administration in brain tumor-induced conditions: SRBC acting as a dual potentiator in regulating the cytokine profile.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Gene Expression Regulation, Enzymologic; Immunity, Cellular; Immunologic Factors; Interferon-gamma; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Intracellular Signaling Peptides and Proteins; Lymphocytes; Microglia; Protein-Tyrosine Kinases; Rats; Receptors, Interleukin; Th1 Cells | 2004 |
Brain tumor inhibition in experimental model by restorative immunotherapy with a corpuscular antigen.
Topics: Adjuvants, Immunologic; Animals; Antigens; Brain Neoplasms; Cell Division; Erythrocytes; Ethylnitrosourea; Female; Immunotherapy, Adoptive; Male; Neutrophils; Phagocytosis; Rats; Rats, Inbred Strains; Rosette Formation; Sheep; Spleen; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured | 2003 |
Documentation of immune profile of microglia through cell surface marker study in glioma model primed by a novel cell surface glycopeptide T11TS/SLFA-3.
Topics: Alkylating Agents; Animals; Biomarkers; Brain; Brain Neoplasms; CD2 Antigens; CD4 Antigens; Cell Membrane; Cell Proliferation; Cell Separation; Erythrocytes; Ethylnitrosourea; Flow Cytometry; Glioma; Glycopeptides; Immunophenotyping; Ligands; Microglia; Microscopy, Electron, Scanning; Protein Binding; Rats; Receptors, Interleukin-2; Rosette Formation; Sheep | 2004 |
CD2-SLFA3/T11TS interaction facilitates immune activation and glioma regression by apoptosis.
Topics: Animals; Apoptosis; Brain Neoplasms; CD2 Antigens; CD58 Antigens; Erythrocytes; Ethylnitrosourea; Female; Flow Cytometry; Genes, MHC Class I; Glioma; Lymphocytes; Macrophages; Male; Microglia; Mutagens; Phosphatidylserines; Protein Binding; Rats; Receptors, Antigen, T-Cell; Rosette Formation; Sheep | 2004 |
Primary and transplanted ENU induced rat tumors in neurooncology.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Magnetic Resonance Imaging; Neoplasm Transplantation; Rats | 2004 |
Ethylnitrosourea induces neural progenitor cell apoptosis after S-phase accumulation in a p53-dependent manner.
Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Carcinogens; Cell Cycle; Cell Transformation, Neoplastic; Disease Models, Animal; DNA Replication; Ethylnitrosourea; Female; G2 Phase; Male; Mice; Mice, Knockout; Neurons; Rats; Rats, Inbred F344; S Phase; Stem Cells; Tumor Suppressor Protein p53 | 2005 |
Isolation of immortalized, INK4a/ARF-deficient cells from the subventricular zone after in utero N-ethyl-N-nitrosourea exposure.
Topics: ADP-Ribosylation Factors; Animals; Brain; Brain Neoplasms; Cell Differentiation; Cells, Cultured; Cerebral Ventricles; Corpus Striatum; Cyclin-Dependent Kinase Inhibitor p16; DNA Primers; Epidermal Growth Factor; Ethylnitrosourea; Female; Male; Membrane Proteins; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Suppressor Protein p14ARF | 2005 |
T11TS/S-LFA3 induces apoptosis of the brain tumor cells: a new approach to characterise the apoptosis associated genetic changes by arbitrarily primed-PCR.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; CD2 Antigens; CD58 Antigens; Disease Models, Animal; DNA Fragmentation; DNA, Neoplasm; Ethylnitrosourea; Female; In Situ Nick-End Labeling; Male; Phosphatidylserines; Polymerase Chain Reaction; Rats; Rats, Inbred Strains | 2005 |
ENU administration causes genomic instability along with single nucleotide polymorphisms in p53 during gliomagenesis: T11TS administration demonstrated in vivo apoptosis of these genetically altered tumor cells.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; CD58 Antigens; DNA Mutational Analysis; Ethylnitrosourea; Exons; Flow Cytometry; Genomic Instability; Glioma; Microsatellite Repeats; Mutagenesis; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Rats; Rats, Inbred Strains; Tumor Suppressor Protein p53 | 2006 |
Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors.
Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Count; Cell Division; Cell Transformation, Neoplastic; Cerebral Ventricles; DNA Damage; Ethylnitrosourea; Female; Gene Expression Regulation; Genes, p53; Genetic Vectors; Glioblastoma; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multipotent Stem Cells; Neoplasms, Radiation-Induced; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells; Time Factors; Tumor Suppressor Protein p53 | 2006 |
Effects of lipid association on lomustine (CCNU) administered intracerebrally to syngeneic 36B-10 rat brain tumors.
Topics: Alkylating Agents; Animals; Antineoplastic Agents, Alkylating; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Injections, Intraventricular; Liposomes; Lomustine; Male; Phospholipids; Rats; Rats, Inbred F344 | 2006 |
Lack of promoting effects of chronic exposure to 1.95-GHz W-CDMA signals for IMT-2000 cellular system on development of N-ethylnitrosourea-induced central nervous system tumors in F344 rats.
Topics: Animals; Brain Neoplasms; Cell Phone; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electromagnetic Fields; Environmental Exposure; Ethylnitrosourea; Female; Male; Neoplasms, Radiation-Induced; Radiation Dosage; Rats; Rats, Inbred F344 | 2007 |
A distinct phenotypic change in gliomas at the time of magnetic resonance imaging detection.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Disease Models, Animal; Disease Progression; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Intermediate Filament Proteins; Magnetic Resonance Imaging; Male; Nerve Tissue Proteins; Nestin; Osteopontin; Phenotype; Rats; Rats, Sprague-Dawley | 2008 |
Dietary prevention of malignant glioma aggressiveness, implications in oxidant stress and apoptosis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Cell Proliferation; Ethylnitrosourea; Female; Fruit; Glioma; Immunohistochemistry; Male; Mitochondria, Liver; Oxidative Stress; Polymerase Chain Reaction; Pregnancy; Rats; RNA, Neoplasm; Vegetables | 2008 |
Lack of a co-promotion effect of 60 Hz rotating magnetic fields on N-ethyl-N-nitrosourea induced neurogenic tumors in F344 rats.
Topics: Animals; Brain Neoplasms; Electromagnetic Fields; Ethylnitrosourea; Female; Male; Neoplasms, Radiation-Induced; Rats; Rats, Inbred F344; Rotation | 2008 |
Regional blood flow and blood-to-tissue transport in five brain tumor models. Implications for chemotherapy.
Topics: Aminoisobutyric Acids; Animals; Astrocytoma; Biological Transport; Brain Neoplasms; Capillary Permeability; Carcinoma 256, Walker; Disease Models, Animal; Ethylnitrosourea; Glioma; Oligodendroglioma; Rats; Regional Blood Flow; Sarcoma, Avian | 1984 |
Fetal antigenicities in chemically induced rat neurogenic tumors.
Topics: Animals; Antigens, Neoplasm; Brain Neoplasms; Cell Migration Inhibition; Ethylnitrosourea; Fetus; Lymphocytes; Male; Neoplasms, Experimental; Rats; Thymus Gland | 1980 |
[In vitro malignant transformation of fetal brain cells exposed in utero to ethylnitrosourea--serological analysis of cell surface antigens of transformed cells (author's transl)].
Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Brain Neoplasms; Cell Transformation, Neoplastic; Epitopes; Ethylnitrosourea; Female; Fetus; Neoplasms, Experimental; Nitrosourea Compounds; Rats | 1981 |
Distribution of bleomycin in ethylnitrosourea-induced gliomas in rats.
Topics: Animals; Biological Assay; Bleomycin; Brain Neoplasms; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1982 |
Changing images of the brain.
Topics: Anatomy; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Glioma; History, 16th Century; History, 17th Century; History, 18th Century; History, 19th Century; History, Ancient; History, Medieval; History, Modern 1601-; Humans; Microscopy, Electron; Neoplasms, Experimental; Rats | 1983 |
Reduction of N-nitroso-N-ethylurea-induced neurogenic tumors by X-radiation: a life-span study in rats.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Glioma; Nervous System Neoplasms; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms; Whole-Body Irradiation | 1984 |
Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Line; Cell Survival; Drug Synergism; Eflornithine; Ethylnitrosourea; Lomustine; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats | 1983 |
[Effect of orally administered zinc on the inducibility of experimental brain tumors in the rat].
Topics: Administration, Oral; Animals; Astrocytoma; Brain Neoplasms; Cocarcinogenesis; Ethylnitrosourea; Glioma; Male; Oligodendroglioma; Rats; Sarcoma; Zinc | 1984 |
Combined effects of drugs and radiation against tumor cells.
Topics: Animals; Brain Neoplasms; Cell Survival; Cells, Cultured; Combined Modality Therapy; Disease Models, Animal; Ethylnitrosourea; Humans; Nitrosourea Compounds; Rats; X-Rays | 1984 |
[Effect of PS-K on experimental neurogenic tumors in rats induced by ethylnitrosourea].
Topics: Adjuvants, Immunologic; Animals; Brain Neoplasms; Ethylnitrosourea; Nervous System Neoplasms; Peripheral Nervous System Neoplasms; Proteoglycans; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1984 |
[Effect of polypeptide factors of the thymus, pineal gland, bone marrow and anterior hypothalamus on the realization of transplacental carcinogenesis].
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Kidney Neoplasms; Male; Neoplasms, Experimental; Peptides; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spinal Cord Neoplasms; Thymus Hormones | 1984 |
Regional blood flow in ethylnitrosourea-induced brain tumors.
Topics: Animals; Astrocytoma; Blood Flow Velocity; Brain Neoplasms; Cerebrovascular Circulation; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains; Regional Blood Flow | 1983 |
Regional blood-to-tissue transport in ethylnitrosourea-induced brain tumors.
Topics: Aminoisobutyric Acids; Animals; Astrocytoma; Blood-Brain Barrier; Brain; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Ethylnitrosourea; Female; Glioma; Kinetics; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
Biochemical and histochemical evaluation of glycosaminoglycans in brain tumors induced in rats by nitrosourea derivatives.
Topics: Age Factors; Animals; Brain Neoplasms; Ethylnitrosourea; Glioma; Glycosaminoglycans; Histocytochemistry; Methylnitrosourea; Nitrosourea Compounds; Rats | 1983 |
[Synergism of hyperthermia and hematoporphyrin derivative].
Topics: Animals; Brain Neoplasms; Cell Division; Combined Modality Therapy; Ethylnitrosourea; Hematoporphyrins; Hyperthermia, Induced; Neurilemmoma; Rats; Rats, Inbred Strains; Temperature | 1984 |
Immunoradiometric and immunohistochemical demonstration of neuron-specific enolase in experimental rat gliomas.
Topics: Animals; Brain; Brain Neoplasms; Cell Line; Ethylnitrosourea; Glioma; Histocytochemistry; Humans; Neoplasms, Experimental; Neurilemmoma; Phosphopyruvate Hydratase; Radioimmunoassay; Rats | 1984 |
[Effect of tumor promoting agents on the in vitro malignant transformation of the fetal rat brain cells exposed in utero to ethylnitrosourea].
Topics: Animals; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Fetus; In Vitro Techniques; Maternal-Fetal Exchange; Nitrosourea Compounds; Phenobarbital; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1984 |
[Mechanisms of the tumor promoting effect of 12-0-tetradecanoyl phorbol 13-acetate on the ethylnitrosourea induced transplacental neurogenic carcinogenesis].
Topics: Animals; Brain Neoplasms; Carcinogens; Chromosome Aberrations; DNA, Neoplasm; Ethylnitrosourea; Female; Gene Expression Regulation; In Vitro Techniques; Maternal-Fetal Exchange; Neoplasm Proteins; Phorbols; Pregnancy; Rats; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thymidine | 1984 |
Lysosomal isozyme patterns in ethylnitrosourea-induced brain tumors.
Topics: Acetylglucosaminidase; Acid Phosphatase; Animals; Arylsulfatases; beta-Galactosidase; Brain; Brain Neoplasms; Ethylnitrosourea; Glucuronidase; Isoelectric Focusing; Isoenzymes; Lysosomes; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1982 |
Microvascular abnormalities in ethylnitrosourea (ENU)-induced rat brain tumors: structural basis for altered blood-brain barrier function.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Cerebrovascular Circulation; Endothelium; Ethylnitrosourea; Glioma; Horseradish Peroxidase; Intercellular Junctions; Microcirculation; Microscopy, Electron; Neoplasms, Experimental; Nitrosourea Compounds; Pinocytosis; Rats; Rats, Inbred Strains | 1983 |
Early stage of development of transplacentally induced glioma with ethylnitrosourea in rats. Sequential historadioautographic and electron microscopic studies.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Division; Ethylnitrosourea; Female; Fetal Diseases; Glioma; Microscopy, Electron; Pregnancy; Rats; Rats, Inbred Strains | 1983 |
In vitro transformation of fetal brain cells from CDF rats exposed in utero to N-ethyl-N-nitrosourea: morphologic and immunologic studies.
Topics: Animals; Animals, Newborn; Antibody Formation; Brain; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Thymectomy; Transplantation, Isogeneic | 1980 |
Glycosaminoglycans of brain tumors transplacentally induced by ENU in the rat.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Glycosaminoglycans; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglia; Oligodendroglioma; Pregnancy; Rats | 1981 |
Experimental chemical production of brain tumors.
Topics: Animals; Brain Neoplasms; Carmustine; Ethylnitrosourea; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats | 1982 |
Malignant transformation of rat neural cells in culture.
Topics: Animals; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Microscopy, Electron, Scanning; Rats | 1982 |
Natural cytotoxicity against chemically induced neurogenic rat tumors.
Topics: Age Factors; Animals; Brain Neoplasms; Cell Division; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Ethylnitrosourea; Female; Glioma; Immunity, Innate; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neurilemmoma; Rats; Spleen; T-Lymphocytes | 1982 |
[Immunoperoxidase method using antiserum against astroprotein for the diagnosis of experimental brain tumors (author's transl)].
Topics: Animals; Astrocytes; Brain Neoplasms; Ethylnitrosourea; Glioma; Humans; Immune Sera; Immunoenzyme Techniques; Neoplasm Proteins; Neoplasms, Experimental; Nerve Tissue Proteins; Rats | 1980 |
Ultrastructural findings in so-called ependymal rat tumors induced by transplacental administration of ethylnitrosourea (ENU).
Topics: Animals; Brain Neoplasms; Cilia; Ependymoma; Ethylnitrosourea; Female; Male; Maternal-Fetal Exchange; Microscopy, Electron; Microtubules; Microvilli; Polyribosomes; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
[The effects of combined chemotherapy (adriamycin/VM/26/CCNU) in brian tumours in adults and animal experiments (author's transl)].
Topics: Adult; Aged; Animals; Brain Neoplasms; Doxorubicin; Drug Therapy, Combination; Ethylnitrosourea; Female; Glioma; Humans; Intracranial Pressure; Lomustine; Male; Middle Aged; Neoplasms, Experimental; Nitrosourea Compounds; Podophyllotoxin; Rats; Survival | 1982 |
DNA template activity in rat brain tumors induced by transplacental administration of ethylnitrosourea.
Topics: Acridine Orange; Animals; Brain Neoplasms; DNA, Neoplasm; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Oligodendroglioma; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Templates, Genetic | 1982 |
Strain differences of tumorigenic effect of neonatally administered N-ethyl-N-nitrosourea in rats.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Male; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Species Specificity; Spinal Cord Neoplasms | 1982 |
[Local cerebral glucose utilization in the ethylnitrosourea-induced rat glioma].
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Ethylnitrosourea; Glioma; Glucose; Neoplasms, Experimental; Rats | 1982 |
[10B compound distribution in rat tissue of transplanted and ethylnitrosourea-induced brain tumors].
Topics: Animals; Boron; Brain Neoplasms; Ethylnitrosourea; Isotopes; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Tissue Distribution | 1982 |
Congenital malformations of the central nervous system and transplacental carcinogenesis: modification of ethylnitrosourea-induced brain tumors in rats by pretreatment with methylazoxymethanol.
Topics: Animals; Azo Compounds; Brain Neoplasms; Ethylnitrosourea; Female; Methylazoxymethanol Acetate; Microcephaly; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains | 1982 |
Transplacental carcinogenic effect of n-nitrosoethylurea in dogs.
Topics: Animals; Brain Neoplasms; Dogs; Ethylnitrosourea; Female; Fetus; Kidney Neoplasms; Male; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Splenic Neoplasms; Thyroid Neoplasms | 1981 |
Spinal tumors induced by neonatal administration of N-ethyl-N-nitrosourea in Wistar rats.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Male; Neoplasms, Experimental; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms; Spinal Nerve Roots; Trigeminal Nerve | 1981 |
Regional blood flow and capillary permeability in the ethylnitrosourea-induced rat glioma.
Topics: Animals; Autoradiography; Brain; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Glioma; Rats; Rats, Inbred Strains; Regional Blood Flow | 1981 |
Metastasis from the brain of transplanted N-ethyl-N-nitrosourea-induced central nervous system tumors in rats.
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Glioma; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
Effect of age at treatment on the incidence and location of neurogenic tumors induced in Wistar rats by a single dose of N-ethyl-N-nitrosourea.
Topics: Age Factors; Animals; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Male; Neoplasms, Experimental; Nervous System Neoplasms; Nitrosourea Compounds; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sex Factors; Spinal Cord Neoplasms; Trigeminal Nerve | 1981 |
[Changes of blood-brain barrier in the ethylnitrosourea induced rat glioma (author's transl)].
Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Rats | 1981 |
[Regional blood flow in the ethylnitrosourea induced rat glioma (author's transl)].
Topics: Animals; Brain Neoplasms; Cerebrovascular Circulation; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1981 |
[Principal fields of research into the pathogenesis of gliomas (author's transl)].
Topics: Animals; Brain Neoplasms; DNA Tumor Viruses; Dogs; Ethylnitrosourea; Female; Glioma; Humans; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Retroviridae | 1981 |
Experimental brain tumors by transplacental ENU. Multifactorial study of the latency period.
Topics: Adenylyl Cyclases; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Hyperplasia; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Time Factors | 1980 |
Influence of chronic Toxoplasma infection on ethylnitrosourea-induced central nervous system tumors in rats.
Topics: Animals; Astrocytoma; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Immunity; Inflammation; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Toxoplasmosis, Animal | 1980 |
Cytotoxic effects of ethylnitrosourea on central nervous system of rat embryos. Special references to carcinogenesis and teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Brain Neoplasms; Cerebral Ventricles; DNA; Embryo, Mammalian; Ethylnitrosourea; Female; Microcephaly; Mitosis; Necrosis; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rosette Formation; Telencephalon | 1980 |
LDH isozyme analyses of ethylnitrosourea-induced central nervous system tumors in rats.
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Isoenzymes; L-Lactate Dehydrogenase; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Rats; Spinal Cord | 1980 |
Role of nerve growth factor in ethylnitrosourea-induced neural carcinogenesis.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Hydroxydopamines; Neoplasms, Experimental; Nerve Growth Factors; Nitrosourea Compounds; Pregnancy; Rats | 1980 |
A case of adult microcephaly.
Topics: Adult; Brain; Brain Diseases; Brain Neoplasms; Choristoma; Ethylnitrosourea; Female; Humans; Methylazoxymethanol Acetate; Microcephaly | 1980 |
Contribution of O6-methylguanine-DNA methyltransferase to monofunctional alkylating-agent resistance in human brain tumor-derived cell lines.
Topics: Alkylating Agents; Antineoplastic Agents; Brain Neoplasms; Cell Adhesion; Colonic Neoplasms; Culture Media; Drug Resistance; Drug Screening Assays, Antitumor; Ethylnitrosourea; Glioma; Medulloblastoma; Methylation; Methylnitronitrosoguanidine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Tumor Cells, Cultured | 1995 |
Growth-inhibiting effect of intratumoral recombinant human tumor necrosis factor on an experimental model of primitive neuroectodermal tumor.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Ethylnitrosourea; Humans; Immunotherapy, Adoptive; Neuroectodermal Tumors, Primitive; Rats; Rats, Wistar; Recombinant Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
The RG2 rat glioma model.
Topics: Animals; Blood-Brain Barrier; Body Weight; Brain; Brain Neoplasms; Cell Transplantation; Ethylnitrosourea; Female; Glioma; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344; Sex Characteristics; Tumor Cells, Cultured | 1995 |
Experimental neurocytomas.
Topics: Animals; Brain Neoplasms; Eosine Yellowish-(YS); Ethylnitrosourea; Glial Fibrillary Acidic Protein; Hematoxylin; Humans; Immunohistochemistry; Mice; Microscopy, Electron; Neuroblastoma; Oligodendroglioma; Paraffin Embedding; Phenotype; Rats; Rats, Wistar; Synaptophysin; Vimentin | 1993 |
Immunohistochemical localization of glycosaminoglycans in experimental rat glioma models.
Topics: Animals; Brain Neoplasms; Chondroitin Sulfates; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioma; Immunohistochemistry; Keratan Sulfate; Male; Rats; Rats, Wistar | 1994 |
Experimental induction of primitive neuro-ectodermal tumours in rats: a re-appraisement of the ENU-model of neurocarcinogenesis.
Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Immunoenzyme Techniques; Male; Microscopy, Electron; Neoplasm Transplantation; Neuroectodermal Tumors, Primitive; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar | 1994 |
Neuroblastic differentiation in ethyl-nitrosourea-induced brain tumors.
Topics: Animals; Brain Neoplasms; Cell Differentiation; Ethylnitrosourea; Tumor Cells, Cultured | 1994 |
Neuronal lineage in ethyl-nitrosourea-induced brain tumors.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Rats | 1994 |
Influence of the postnatal administration of tumor necrosis factor plus interferon-alpha 2b on the development of ethyl-nitrosourea-induced brain tumors in rats.
Topics: Aging; Animals; Brain Neoplasms; Ethylnitrosourea; Female; Interferon alpha-2; Interferon-alpha; Neurilemmoma; Oligodendroglioma; Pregnancy; Rats; Rats, Wistar; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Anitumoral effect of thallium against N-ethyl-N-nitroso-urea-induced brain tumors.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Ethylnitrosourea; Female; Injections; Placenta; Pregnancy; Rats; Rats, Wistar; Thallium | 1994 |
Surface antigens of cell subpopulations in prenatal rat brain are expressed in a characteristic non-random pattern on their ethylnitrosourea-induced malignant counterparts.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Brain; Brain Neoplasms; Cell Line; Ethylnitrosourea; Female; Fetus; Flow Cytometry; Rats; Rats, Inbred Strains | 1994 |
Characterization of brain and bone-metastasizing clones selected from an ethylnitrosourea-induced rat mammary carcinoma.
Topics: Animals; Bone Neoplasms; Brain Neoplasms; Carcinoma; Clone Cells; DNA, Neoplasm; Ethylnitrosourea; Female; Mammary Neoplasms, Experimental; Microscopy, Electron; Neoplasm Metastasis; Rats | 1994 |
Gangliosides modulate the development of ethyl-nitrosourea induced brain tumors in rats.
Topics: Animals; Brain Neoplasms; Cattle; Ethylnitrosourea; Female; Gangliosides; Immunologic Factors; Pregnancy; Rats; Rats, Wistar | 1994 |
Characterization and chemosensitivity of two cell lines derived from human glioblastomas.
Topics: Animals; Brain Neoplasms; Drug Resistance; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioblastoma; Humans; Karyotyping; Male; Methyltransferases; Mice; Mice, Inbred BALB C; Middle Aged; Neoplasm Transplantation; Nimustine; O(6)-Methylguanine-DNA Methyltransferase; Occipital Lobe; Parietal Lobe; S100 Proteins; Tumor Cells, Cultured | 1993 |
Spermidine acetylation in N1 and N8 position in rat brain and in N-ethyl-N-nitrosourea-induced gliomas.
Topics: Acetylation; Acetyltransferases; Animals; Brain; Brain Neoplasms; Catalysis; Cytosol; Ethylnitrosourea; Female; Glioma; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spermidine | 1994 |
[In vitro ENU-induced carcinogenesis of rat fetal astroglia--biological character of mutant glial cell].
Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Fetus; Flow Cytometry; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Rats; Rats, Wistar; Tumor Stem Cell Assay | 1993 |
Complementary tumor induction in neural grafts exposed to N-ethyl-N-nitrosourea and an activated myc gene.
Topics: Animals; Base Sequence; Brain; Brain Neoplasms; Brain Tissue Transplantation; Cell Transformation, Neoplastic; Cocarcinogenesis; Ethylnitrosourea; Female; Gene Expression Regulation, Neoplastic; Genes, myc; Male; Maternal-Fetal Exchange; Molecular Sequence Data; Pregnancy; Rats; Rats, Inbred F344; Transfection | 1993 |
Diamine oxidase activity in rat brain carcinogenesis and in gliomas.
Topics: Amine Oxidase (Copper-Containing); Animals; Brain Neoplasms; Ethylnitrosourea; Female; Fetus; Glioma; Male; Precancerous Conditions; Pregnancy; Prenatal Exposure Delayed Effects; Putrescine; Rats | 1993 |
Study of the post-natal effects of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. II. Influence of low-molecular-weight polypeptide factors from the thymus, pineal gland, bone marrow, anterior hypothalamus, brain
Topics: Animals; Anticarcinogenic Agents; Bone Marrow; Brain; Brain Neoplasms; Carcinogens; Central Nervous System Neoplasms; Cerebral Cortex; Ethylnitrosourea; Female; Hypothalamus, Anterior; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms, Experimental; Peptides; Peripheral Nervous System Neoplasms; Pineal Gland; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms; Thymus Gland; Tissue Extracts | 1996 |
Study of post-natal effect of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. III. Inhibitory action of indomethacin, voltaren, theophylline and epsilon-aminocaproic acid.
Topics: Aminocaproic Acid; Animals; Anticarcinogenic Agents; Brain Neoplasms; Carcinogens; Central Nervous System Neoplasms; Diclofenac; Ethylnitrosourea; Female; Indomethacin; Kidney Neoplasms; Maternal-Fetal Exchange; Neoplasms, Experimental; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spinal Cord Neoplasms; Theophylline | 1996 |
Gangliosides modulate the growth rate and cell phenotype of a murine primitive neuro-ectodermal tumour.
Topics: Animals; Biomarkers, Tumor; Brain; Brain Neoplasms; Cell Differentiation; Cell Division; Ethylnitrosourea; Gangliosides; Injections, Intralesional; Neoplasm Transplantation; Neuroectodermal Tumors, Primitive; Phenotype; Rats; Rats, Wistar; Tumor Cells, Cultured | 1996 |
Loss of p53 is an early event in induction of brain tumors in mice by transplacental carcinogen exposure.
Topics: Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Fetus; Gene Deletion; Genes, p53; Humans; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pregnancy | 1997 |
Lectin histochemistry of ethylnitrosourea-induced oligodendrogliomas in the rat.
Topics: Animals; Brain; Brain Neoplasms; Carcinogens; Concanavalin A; Ethylnitrosourea; Immunohistochemistry; Lectins; Oligodendroglioma; Peanut Agglutinin; Rats; Rats, Wistar | 1997 |
Effects of basic fibroblast growth factor on in vivo cerebral tumorigenesis in rats.
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Fibroblast Growth Factor 2; Glioma; Humans; Male; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1997 |
Magnetic resonance imaging of rat head with a high-strength (4.7 T) magnetic field.
Topics: Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Head; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley; Rodent Diseases | 1997 |
Immune-cell system provides the development of extraneural tumors in the ethyl-nitrosourea model of neurocarcinogenesis.
Topics: Animals; Brain Neoplasms; Cyclosporine; Ethylnitrosourea; Immunosuppressive Agents; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Neurilemmoma; Oligodendroglioma; Rats; Rats, Wistar | 1998 |
Drug resistance and apoptosis in ENU-induced rat brain tumors treated with anti-cancer drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; DNA Nucleotidylexotransferase; Drug Resistance, Neoplasm; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Nimustine; Pregnancy; Rats; Rats, Wistar; Vincristine | 1998 |
gp130RB13-6-positive neural progenitor cells are susceptible to the oncogenic effect of ethylnitrosourea in pre-natal rat brain.
Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Fetus; Humans; Lysosomal Membrane Proteins; Membrane Glycoproteins; Neoplasms, Nerve Tissue; Neurons; Rats; Rats, Inbred Strains; Stem Cells; Tumor Cells, Cultured | 1998 |
Increased telomerase activity and absence of p53 mutation in oligoastrocytomas induced by N-ethyl-N-nitrosourea in rats.
Topics: Animals; Astrocytoma; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Genes, p53; Male; Neoplasm Proteins; Rats; Rats, Inbred F344; Telomerase | 1998 |
Determinants of carcinogen-induced malignant conversion in rat brain: proliferative properties of neural precursor cell subpopulations analyzed by multi-parameter flow cytometry.
Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Ethylnitrosourea; Flow Cytometry; In Vitro Techniques; Rats; Rats, Inbred Strains; Stem Cells | 1998 |
Changes in VEGF expression and in the vasculature during the growth of early-stage ethylnitrosourea-induced malignant astrocytomas in rats.
Topics: Animals; Astrocytoma; Blood Vessels; Brain Neoplasms; Endothelial Growth Factors; Ethylnitrosourea; Female; Immunoenzyme Techniques; Lymphokines; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; von Willebrand Factor | 1998 |
Effect of dietary vitamin A or N-acetylcysteine on ethylnitrosourea-induced rat gliomas.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Free Radical Scavengers; Glioma; Neuroectodermal Tumors; Pregnancy; Rats; Rats, Sprague-Dawley; Survival Analysis; Vitamin A | 1998 |
Molecular genetic characterisation of intracerebrally transplanted brain tumours.
Topics: Animals; Base Sequence; Brain Neoplasms; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; DNA Primers; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Ethylnitrosourea; Genes, bcl-1; Genes, p16; Genes, Retinoblastoma; Glioma; Molecular Sequence Data; Neoplasm Transplantation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Rats; Rats, Inbred Strains | 1999 |
Laminin receptor alpha6beta4 integrin is highly expressed in ENU-induced glioma in rat.
Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Blood Vessels; Brain Neoplasms; Cell Division; Dimerization; Ethylnitrosourea; Female; Glioma; Humans; Integrin alpha6beta4; Integrins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; RNA, Messenger; Transcription, Genetic | 1999 |
Distribution and activity of transglutaminase in rat brain carcinogenesis and in gliomas.
Topics: Animals; Animals, Newborn; Brain; Brain Neoplasms; Carcinogenicity Tests; Carcinogens; Cytosol; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Subcellular Fractions; Time Factors; Transglutaminases | 1999 |
Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats chronically exposed to 836 MHz modulated microwaves.
Topics: Animals; Brain Neoplasms; Carcinogens; Central Nervous System Neoplasms; Cocarcinogenesis; Disease Models, Animal; Ethylnitrosourea; Female; Incidence; Male; Microwaves; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Spinal Cord Neoplasms | 1999 |
Mutagenesis of a single AT basepair in mice transgenic for PhiX174 am3, cs70. II. Brain.
Topics: Animals; Animals, Newborn; Bacteriophage phi X 174; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Genes, Viral; Genetic Vectors; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Mutagens; Mutation | 1999 |
Effect of cations on the formation of DNA alkylation products in DNA reacted with 1-(2-Chloroethyl)-1-nitrosourea.
Topics: Alkylating Agents; Alkylation; Animals; Brain Neoplasms; Cations; Cattle; Chromatography, High Pressure Liquid; DNA Adducts; DNA, Neoplasm; Ethylnitrosourea; Magnesium Chloride; Rats; Sodium Chloride; Spermine; Tumor Cells, Cultured | 1999 |
Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties.
Topics: Animals; Brain; Brain Neoplasms; Carcinogens; Endothelium, Vascular; Ethylnitrosourea; Female; Intercellular Junctions; Microcirculation; Neovascularization, Pathologic; Pregnancy; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Retroviridae Infections; Sarcoma Viruses, Murine; Sarcoma, Experimental; Tumor Cells, Cultured; Tumor Virus Infections | 1999 |
Allele-specific losses of heterozygosity on chromosomes 1 and 17 revealed by whole genome scan of ethylnitrosourea-induced BDIX x BDIV hybrid rat gliomas.
Topics: Alleles; Animals; Brain Neoplasms; Chimera; Chromosome Mapping; Chromosomes; Ethylnitrosourea; Genetic Linkage; Genetic Markers; Glioma; Humans; Loss of Heterozygosity; Rats; Rats, Inbred Strains | 1999 |
Evaluation of the potential promoting effect of 60 Hz magnetic fields on N-ethyl-N-nitrosourea induced neurogenic tumors in female F344 rats.
Topics: Animals; Body Weight; Brain Neoplasms; Central Nervous System Neoplasms; Electromagnetic Fields; Ethylnitrosourea; Female; Glioma; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats exposed to frequency-modulated microwave fields.
Topics: Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Female; Gestational Age; Male; Microwaves; Neoplasms, Radiation-Induced; Pregnancy; Prenatal Exposure Delayed Effects; Radio Waves; Rats; Rats, Inbred F344; Spinal Cord Neoplasms; Survival; Weaning | 2000 |
Immunohistochemical analysis of beta-catenin in N-ethyl-N-nitrosourea-induced rat gliomas: implications in regulation of angiogenesis.
Topics: Animals; beta Catenin; Blood Vessels; Brain Neoplasms; Cytoskeletal Proteins; Ethylnitrosourea; Female; Glioma; Immunohistochemistry; Intracellular Membranes; Neovascularization, Pathologic; Nucleolus Organizer Region; Rats; Rats, Wistar; Reference Values; Silver; Staining and Labeling; Trans-Activators | 2000 |
The effects of 860 MHz radiofrequency radiation on the induction or promotion of brain tumors and other neoplasms in rats.
Topics: Animals; Brain Neoplasms; Cell Phone; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glioma; Male; Neoplasms; Neoplasms, Radiation-Induced; Neurilemmoma; Peripheral Nervous System Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Radio Waves; Rats; Rats, Sprague-Dawley; Spinal Cord Neoplasms; Spinal Nerves | 2001 |
Magnetic resonance imaging of ethyl-nitrosourea-induced rat gliomas: a model for experimental therapeutics of low-grade gliomas.
Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Carcinogens; Diet; Disease Models, Animal; Diterpenes; Ethylnitrosourea; Glioma; Indoles; Magnetic Resonance Imaging; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Pyrroles; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Retinyl Esters; Survival Analysis; Time Factors; Vitamin A | 2001 |
Neural precursor cell apoptosis and glial tumorigenesis following transplacental ethyl-nitrosourea exposure.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Caspase 3; Caspase 9; Caspases; Ethylnitrosourea; Female; Gene Targeting; Genes, p53; Glioma; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Mice, Knockout; Neurons; Placenta; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Stem Cells | 2001 |
The antimalarials quinacrine and chloroquine potentiate the transplacental carcinogenic effect of ethylnitrosourea on ependymal cells.
Topics: Animals; Antimalarials; Brain Neoplasms; Carcinogens; Chloroquine; Drug Synergism; Ependyma; Ependymoma; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Immunoenzyme Techniques; Male; Pregnancy; Prenatal Exposure Delayed Effects; Quinacrine; Rats; Rats, Wistar; Spinal Cord Neoplasms; Synaptophysin | 2001 |
Decreased glucocorticoid induction of brain glycerol phosphate dehydrogenase following transplacental carcinogenesis with ethylnitrosourea.
Topics: Animals; Brain; Brain Neoplasms; Enzyme Induction; Ethylnitrosourea; Female; Glucocorticoids; Glycerolphosphate Dehydrogenase; Hydrocortisone; Liver; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Tyrosine Transaminase | 1977 |
The hexose monophosphate pathway in ethylnitrosourea induced tumors of the nervous system.
Topics: Animals; Animals, Newborn; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glucose; Hexosephosphates; In Vitro Techniques; Male; NADP; Peripheral Nervous System Neoplasms; Phenazines; Rats; Spinal Cord Neoplasms | 1978 |
Chromosome analysis of experimental rat glial tumor(1)--correlation of chromosome changes between glial tumors and fetal brain tissue of rats after a transplacental exposure to ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Chromosomes; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
[Experimental brain tumors induced by transplacental administration of ethylnitrosourea. (2) Vascular constitution of experimental brain tumors].
Topics: Animals; Bleomycin; Brain Neoplasms; Cerebral Angiography; Cobalt Radioisotopes; Ethylnitrosourea; Female; Hydrocortisone; Maternal-Fetal Exchange; Microradiography; Neoplasms, Experimental; Nitrosourea Compounds; Photometry; Pregnancy; Rats | 1977 |
[Experimental brain tumors produced transplacentally by ethylnitrosourea (IV) (author's transl)].
Topics: Animals; Bleomycin; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Hydrocortisone; Maternal-Fetal Exchange; Methylprednisolone; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
[Chromosome analysis of experimental rat brain tumor (II)--chromosome changes of brain tissue cells during pre-induction stage of the tumor (author's transl)].
Topics: Animals; Brain; Brain Neoplasms; Cells, Cultured; Chromosome Aberrations; Ethylnitrosourea; Female; Neoplasms, Experimental; Precancerous Conditions; Rats | 1978 |
[Uptake of bleomycin by ethylnitrosourea-induced rat brain tumors (author's transl)].
Topics: Animals; Bleomycin; Brain Chemistry; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Glioma; Neoplasms, Experimental; Neurilemmoma; Rats; Spinal Cord Neoplasms | 1979 |
Strand breakage in rat brain DNA and its repair induced by ethylnitrosourea in vivo.
Topics: Animals; Animals, Newborn; Brain; Brain Neoplasms; DNA; DNA Repair; Ethylnitrosourea; Female; Fetus; Nitrosourea Compounds; Nucleic Acid Conformation; Pregnancy; Rats | 1975 |
Macrophages in brain tumours induced transplacentally by N-ethyl-N-nitrosourea in rats: an electron-microscope study.
Topics: Animals; Brain Edema; Brain Neoplasms; Cerebral Hemorrhage; Ethylnitrosourea; Female; Glioma; Inclusion Bodies; Leukocytes; Lipids; Lysosomes; Macrophages; Microscopy, Electron; Mitosis; Monocytes; Myelin Sheath; Necrosis; Nerve Degeneration; Nitrosourea Compounds; Phagocytosis; Pregnancy; Rats | 1975 |
[Experimental investigations on the accumulation of radioactive compounds in autochtonal tumors in the rat (author's transl)].
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Chlormerodrin; Ethylnitrosourea; Female; Humans; Indium; Male; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Pentetic Acid; Radioisotopes; Rats; Serum Albumin | 1975 |
Chemotherapeutic effects of some alkylating derivatives of nitrosourea on the development of tumors transplacentally induced in rats by ENU.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Ethylnitrosourea; Female; Fetal Diseases; Glioma; Neoplasms, Experimental; Neoplasms, Nerve Tissue; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats | 1976 |
Embryonal neoplasms in the opossum: a new model for solid tumors of infancy and childhood.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Jaw Neoplasms; Kidney Neoplasms; Liver Neoplasms; Neoplasms, Experimental; Neoplasms, Germ Cell and Embryonal; Opossums | 1976 |
The effect of combined chronic hypoxia and N-ethyl-N-nitrosourea on the carotid bodies of rats.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Carotid Body; Carotid Body Tumor; Ethylnitrosourea; Female; Hypertrophy; Hypoxia; Male; Nitrosourea Compounds; Paraganglioma, Extra-Adrenal; Rats | 1976 |
[Long-term cultures of experimental CNS tumours as models in neurooncological research (author's transl)].
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Division; Cell Transformation, Neoplastic; Culture Techniques; Ethylnitrosourea; Glioma; Methylnitrosourea; Neoplasms, Experimental; Neurilemmoma; Rats; Rats, Inbred Strains; Time Factors | 1976 |
Morphologic and biochemical characteristics of transplantable neurogenic tumors induced by N-ethyl-N-nitrosourea in inbred BD IX rats.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain Neoplasms; Clone Cells; Ethylnitrosourea; Female; Glioma; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Rats, Inbred Strains; S100 Proteins; Transplantation, Isogeneic | 1979 |
Cellular heterogeneity in an ethylnitrosourea-induced glioma: malignancy, karyology and other properties of tumour cell types.
Topics: Animals; Brain Neoplasms; Bucladesine; Clone Cells; Ethylnitrosourea; Female; Glioma; Glucosephosphate Dehydrogenase; Karyotyping; Neoplasms, Experimental; Rats | 1979 |
Nitrosourea-induced brain tumors: an in vivo and in vitro tumor model system.
Topics: Animals; Brain Neoplasms; Cell Division; Cells, Cultured; Disease Models, Animal; Ethylnitrosourea; Female; Glioma; Immunosuppression Therapy; Male; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred Strains; Thymus Gland; Time Factors; Transplantation, Isogeneic | 1978 |
Analysis of N-ethyl-N-nitrosourea-induced brain carcinogenesis by sequential culturing during the latent period. I. Morphology and tumorigenicity of the cultured cells and their growth in agar.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred Strains; Time Factors | 1978 |
Analysis of N-ethyl-N-nitrosourea-induced brain carcinogenesis by sequential culturing during the latent period. II. Morphology of the tumors induced by cell cultures.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Isogeneic | 1978 |
Surface structure of fetal rat brain cells during neoplastic transformation in cell culture.
Topics: Animals; Brain Neoplasms; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Microscopy, Electron, Scanning; Neoplasms, Experimental; Precancerous Conditions; Pregnancy; Rats; Time Factors | 1978 |
Transmission electron microscopy of fetal rat brain cells during neoplastic transformation in cell culture.
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
[Induction of tumours by different endogenously formed N-nitroso-ureas in the hooded rat (author's transl)].
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Lymphoma, Large B-Cell, Diffuse; Maternal-Fetal Exchange; Neoplasms; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Trigeminal Nerve | 1977 |
Increased expression of actin-like protein in human and ethylnitrosourea-induced tumors of the nervous system.
Topics: Actins; Animals; Antibodies; Astrocytoma; Brain Neoplasms; Culture Techniques; Ethylnitrosourea; Fluorescent Antibody Technique; Humans; Meningioma; Neoplasm Proteins; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Rats | 1977 |
[Immunohistological diagnosis of human and experimental brain tumors using antiserum to astroprotein (author's transl)].
Topics: Animals; Astrocytoma; Brain Neoplasms; Cerebral Ventricle Neoplasms; Ethylnitrosourea; Fluorescent Antibody Technique; Glioma; Humans; Immune Sera; Neoplasm Proteins; Neoplasms, Experimental; Oligodendroglioma; Rats | 1979 |
Neuroblasts in cerebral tumors induced by ethylnitrosourea in rats. A fine structrual study.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Medulla Oblongata; Neoplasms, Experimental; Neuroglia; Neurons; Organoids; Pregnancy; Rats | 1977 |
The development of experimental brain tumours. A sequential light and electron microscope study of the subependymal plate. I. Early lesions (abnormal cell clusters).
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
The development of experimental brain tumours a sequential light and electron microscope study of the subependymal plate. II. Microtumours.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Pregnancy; Rats; Time Factors | 1979 |
Immunization against ethylnitrosourea-induced autochthonous neurogenic rat tumours.
Topics: Animals; Antigens, Neoplasm; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Immunization; Male; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred F344 | 1979 |
Teratogenic and carcinogenic effects of some chemicals during perinatal life in rats, Syrian golden hamsters, and minipigs.
Topics: Animals; Brain Neoplasms; Carcinogens; Cricetinae; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Mesocricetus; Neoplasms, Experimental; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms; Swine; Teratogens | 1979 |
Ganglioside composition of chemically induced rat neural tumors and characterization of hematoside from neurinomas.
Topics: Animals; Brain Chemistry; Brain Neoplasms; Ethylnitrosourea; Gangliosides; Neoplasms, Experimental; Neurons; Rats; Sialic Acids; Spinal Cord | 1979 |
Cerebral tumours induced by ENU; changes of adenylate cyclase activity in the tumour latency time.
Topics: Adenylyl Cyclases; Animals; Brain Neoplasms; Brain Stem; Ethylnitrosourea; Female; Frontal Lobe; Glioma; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats; Temporal Lobe | 1979 |
[The biochemical analysis of the experimental tumor tissues of the rat brain induced by ethylnitrosourea (author's transl)].
Topics: Animals; Brain Chemistry; Brain Neoplasms; DNA, Neoplasm; Ethylnitrosourea; Fatty Acids, Nonesterified; Female; Glioma; Neoplasms, Experimental; Nitrosourea Compounds; Rats; RNA, Neoplasm | 1979 |
Transplantability and metastatic potential of chemically induced rat brain tumours.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Male; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1979 |
Fc gamma receptors receptors on fetal rat brain cells during neoplastic transformation in culture after exposure to ethylnitrosourea in vivo.
Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Receptors, Fc | 1979 |
[Experimental brain tumor produced transplacentally by ethylnitrosourea (3). Autoradiographic studies on tumor cell proliferation].
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Division; Cell Transformation, Neoplastic; DNA, Neoplasm; Ethylnitrosourea; Female; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
[Effect of irradiation to carcinogenesis by transplacental ethylnitrosourea in BD--IX rat (author's transl)].
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain Neoplasms; Cerebral Cortex; Embryo, Mammalian; Ethylnitrosourea; Female; Glioma; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats | 1978 |
Chemotherapy studies of various nitrosoureas: prevention of development of ethylnitrosourea-induced tumors in the nervous system.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Neoplasms, Experimental; Nitrogen Mustard Compounds; Nitrosourea Compounds; Pregnancy; Rats; Rats, Inbred F344 | 1977 |
Cerebral tumors induced by transplacental ENU: study of the different tumoral stages, particularly of early proliferations.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Experimental; Neurilemmoma; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Time Factors | 1978 |
Fibrinolytic activity of cultured cells derived during ethylnitrosourea-induced carcinogenesis of rat brain.
Topics: Animals; Brain Neoplasms; Cell Line; Clone Cells; Ethylnitrosourea; Fibrinolysis; Glioma; Plasminogen; Rats; Time Factors | 1978 |
[Combined transplacental carcinogenic action of N-nitrosomethylurea (NMU) and N-nitrosoethylurea (NEU) in rats].
Topics: Animals; Brain Neoplasms; Carcinogens; Dose-Response Relationship, Drug; Drug Interactions; Ethylnitrosourea; Female; Gestational Age; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Placenta; Pregnancy; Rats; Teratogens | 1978 |
[Early stages of experimental brain tumours in rats. Investigation of serial sections (author's transl)].
Topics: Animals; Astrocytoma; Basal Ganglia; Brain Neoplasms; Brain Stem; Cerebral Cortex; Ethylnitrosourea; Female; Glioma; Hippocampus; Neoplasms, Experimental; Oligodendroglioma; Pregnancy; Rats; Sarcoma; Time Factors | 1978 |
[Organ cultures of embryonal rat brain tissue (hippocampal area) in a study of the transplacental effect of nitrosoethylurea].
Topics: Adenoma; Animals; Brain Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Hippocampus; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Organ Culture Techniques; Organ Specificity; Pregnancy; Rats | 1978 |
The immunocytochemical localization of GFA protein in experimental murine CNS tumors.
Topics: Animals; Astrocytes; Brain Neoplasms; Cranial Nerve Neoplasms; Ependymoma; Ethylnitrosourea; Glioma; Methylcholanthrene; Neoplasms, Experimental; Nerve Tissue Proteins; Neurilemmoma; Oligodendroglioma; Rats; Spinal Cord Neoplasms; Trigeminal Nerve | 1979 |
Influence of five different postnatal lifelong treatments on the transplacental carcinogenicity of ethylnitrosourea in Sprague-Dawley rats.
Topics: Albumins; Animals; BCG Vaccine; Brain Neoplasms; Cyclophosphamide; Ethylnitrosourea; Female; Hydrocortisone; Immunotherapy; Male; Mammary Neoplasms, Experimental; Maternal-Fetal Exchange; Mycobacterium bovis; Neoplasms, Experimental; Nicotine; Nitrosourea Compounds; Pregnancy; Rats; Spinal Neoplasms | 1976 |
[Histochemical demonstration of a zinc activated tartrate resistant acid phosphatase in experimentally induced glial microtumors of the rat brain (author's transl)].
Topics: Acid Phosphatase; Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Histocytochemistry; Male; Oligodendroglioma; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tartrates; Zinc | 1975 |
Some results and prospects of transplacental carcinogenesis studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Nervous System Diseases; Nitrosourea Compounds; Organ Specificity; Placenta; Pregnancy; Rats | 1976 |
Short and long term effects of methyl- and ethylnitrosourea (MNU & ENU) on the developing nervous system of the rat. I. Long term effects: the induction of (multiple) gliomas.
Topics: Age Factors; Animals; Animals, Newborn; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Male; Meningioma; Methylnitrosourea; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1977 |
Prenatal multicarcinogenesis by ethylnitrosourea in mice.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ethylnitrosourea; Female; Fetus; Gestational Age; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Ovarian Neoplasms; Peripheral Nervous System Neoplasms; Pregnancy; Sex Factors; Stomach Neoplasms | 1977 |
The role of the subependymal plate in the origin of gliomas induced by ethylnitrosourea in the rat brain.
Topics: Animals; Brain; Brain Neoplasms; Corpus Callosum; Ethylnitrosourea; Female; Glioma; Microscopy, Electron; Neoplasms, Experimental; Neurons; Nitrosourea Compounds; Pregnancy; Rats | 1977 |
Neurochemical properties of cell lines from N-ethyl-N-nitrosourea induced rat tumors.
Topics: Animals; Brain Neoplasms; Cell Line; Ethylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Sodium; Tetrodotoxin | 1977 |
The multipotential carcinogenic action of N-ethyl-N-nitrosourea administered neonatally to mice.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Neoplasms, Multiple Primary; Nitrosourea Compounds; Species Specificity | 1976 |
A sequential in vivo-in vitro study of carcinogenesis induced in the rat brain by ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Ethylnitrosourea; Female; Glioma; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
The origin of experimental brain tumours: a sequential study.
Topics: Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Nitrosourea Compounds; Pregnancy; Rats | 1976 |
[Experimental brain neoplasm induced transplacentally by ethylnitrosourea (ENU). (1) Sequential, localized observations and pathological studies of microtumors].
Topics: Animals; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats | 1976 |
[Experimental brain neoplasm induced by ethylnitrosourea. Frequency of incidence and neurological manifestation in rats].
Topics: Aggression; Animals; Astrocytoma; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Humans; Meningioma; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Trigeminal Nerve | 1976 |
New cell surface antigens in rat defined by tumors of the nervous system.
Topics: Animals; Antigens; Antigens, Neoplasm; Brain Neoplasms; Cell Line; Cell Membrane; Cell Survival; Clone Cells; Ethylnitrosourea; Fluorescent Antibody Technique; Lymphoma; Mice; Neoplasms, Experimental; Peripheral Nervous System Neoplasms; Rats; Rats, Inbred WF | 1975 |
RNA polymerase activity in homotransplanted rat brain tumors initially induced by ethylnitrosourea.
Topics: Amanitins; Animals; Autoradiography; Brain Neoplasms; Cell Nucleolus; Cell Nucleus; Cycloheximide; DNA-Directed RNA Polymerases; DNA, Neoplasm; Endoplasmic Reticulum; Ethylnitrosourea; Fibrosarcoma; Glioma; Guanosine Triphosphate; Neoplasm Transplantation; Neoplasms, Experimental; Neurofibroma; Rats; Rifampin; Transplantation, Homologous | 1975 |
The effect of BCNU, CCNU and MeCCNU in the prevention of the development of tumors of the nervous system.
Topics: Animals; Brain Neoplasms; Carmustine; Ethylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine | 1975 |
Effects of nerve growth factor administration of N-ethyl-N-nitrosourea carcinogenesis.
Topics: Animals; Brain Neoplasms; Cells, Cultured; Drug Interactions; Ethylnitrosourea; Female; Male; Methylcholanthrene; Neoplasms, Experimental; Nerve Growth Factors; Neuroblastoma; Nitrosourea Compounds; Pregnancy; Rats; Urogenital Neoplasms | 1975 |
Problems in transplacental carcinogenesis.
Topics: Animals; Brain Neoplasms; Ependymoma; Ethylnitrosourea; Female; Fetal Diseases; Maternal-Fetal Exchange; Neoplasms; Neoplasms, Experimental; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms | 1975 |
Induction of neurogenic and lymphoid neoplasms by the feeding of threshold levels of methyl- and ethylnitrousourea precursors to adult rats.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Lymphoma; Mammary Neoplasms, Experimental; Methylnitrosourea; Methylurea Compounds; Neoplasms, Experimental; Nitrites; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pituitary Neoplasms; Rats; Urea | 1975 |
Neoplastic transformation of fetal rat brain cells in culture after exposure to ethylnitrosourea in vivo.
Topics: Animals; Brain; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Models, Biological; Neoplasms, Experimental; Nitrosourea Compounds; Pregnancy; Rats; Time Factors | 1975 |
Inhibitory effect of sodium ascorbate on ethylurea and sodium nitrite carcinogensis and negative findings in progeny after intestinal inoculation of precursors into pregnant hamsters.
Topics: Animals; Ascorbic Acid; Astrocytoma; Brain Neoplasms; Cecum; Cricetinae; Ethylnitrosourea; Female; Intubation, Gastrointestinal; Male; Maternal-Fetal Exchange; Neoplasms, Experimental; Nitrites; Nitroso Compounds; Peripheral Nervous System Neoplasms; Pons; Pregnancy; Sex Factors; Urea | 1975 |
[Experimental results with new radiopharmaceuticals in autochthon brain tumors of rats (author's transl)].
Topics: Animals; Brain Neoplasms; Copper; Ethylnitrosourea; Gallium; Iron Radioisotopes; Methods; Neoplasms, Experimental; Radioisotopes; Radionuclide Imaging; Rats; Technetium | 1975 |
Topographic blood flow in experimental nervous system tumors and surrounding tissues.
Topics: Animals; Brain Neoplasms; Cerebrovascular Circulation; Ethylnitrosourea; Rats; Spinal Cord; Spinal Cord Neoplasms | 1975 |
Studies of the morphology and tumorigenicity of experimental brain tumours in tissue culture.
Topics: Animals; Brain Neoplasms; Culture Techniques; Ethylnitrosourea; Glioma; Neoplasm Transplantation; Neoplasms, Experimental; Rats | 1976 |
Studies on experimental malignant nerve sheath tumors maintained in tissue and organ culture systems. III. Melanin pigment and melanogenesis in experimental neurogenic tumors: a reappraisal of the histogenesis of pigmented nerve sheath tumors.
Topics: Animals; Brain Neoplasms; Culture Techniques; Ependymoma; Ethylnitrosourea; Female; Male; Melanins; Melanoma; Meninges; Microscopy, Electron; Myelin Sheath; Neurilemmoma; Peripheral Nervous System Neoplasms; Rats | 1976 |
Angiogenic activity of the K-fgf/hst oncogene in neural transplants.
Topics: Animals; Antisense Elements (Genetics); Brain Neoplasms; Brain Tissue Transplantation; Caudate Nucleus; Endothelium, Vascular; Ethylnitrosourea; Female; Fetal Tissue Transplantation; Fetus; Fibroblast Growth Factor 4; Fibroblast Growth Factors; Growth Substances; Humans; Injections; Neovascularization, Pathologic; Neurons; Oncogenes; Placenta; Pregnancy; Proto-Oncogene Proteins; Putamen; Rats; Rats, Inbred F344; Receptors, Cell Surface; Receptors, Fibroblast Growth Factor; Retroviridae; Transfection | 1992 |
[Effect of pretreatment with N-methyl-N-nitrosourea or streptozotocin on the cytotoxicity and the induction of sister chromatid exchanges in human and rodent brain tumor cells treated with chloroethylnitrosourea].
Topics: Animals; Brain Neoplasms; Carmustine; Cell Survival; Drug Resistance; Drug Synergism; Ethylnitrosourea; Glioma; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344; Sister Chromatid Exchange; Streptozocin; Tumor Cells, Cultured | 1992 |
Immunohistochemical observations on rat radial glia: relationship with the origin of ethylnitrosourea-induced tumors.
Topics: Animals; Astrocytes; Brain Neoplasms; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Microscopy, Immunoelectron; Neuroglia; Pregnancy; Rats; Rats, Inbred F344; Vimentin | 1992 |
Synaptophysin expression in "ependymal tumors" induced by ethyl-nitrosourea in rats.
Topics: Animals; Brain Neoplasms; Ependyma; Ependymoma; Ethylnitrosourea; Female; Immunohistochemistry; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Wistar; Synaptophysin | 1992 |
Immunohistochemical localization of gangliosides in ENU-induced rat glioma.
Topics: Adult; Aging; Animals; Animals, Newborn; Brain; Brain Injuries; Brain Neoplasms; Embryonic and Fetal Development; Ethylnitrosourea; Female; Fetus; Gangliosides; Glioma; Humans; Immunohistochemistry; Infant, Newborn; Rats; Tissue Distribution; Wounds, Stab | 1992 |
Influence of recombinant interleukin-2 and tumor necrosis factor-alpha on the development of ethyl nitrosourea-induced brain tumors.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Interleukin-2; Neurilemmoma; Oligodendroglioma; Rats; Rats, Wistar; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1992 |
Expression of neuronal and glial markers in so-called oligodendroglial tumors induced by transplacental administration of ethyl-nitrosourea in the rat.
Topics: Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Differentiation; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Histocytochemistry; Neurofilament Proteins; Neuroglia; Neurons; Oligodendroglia; Oligodendroglioma; Rats; Rats, Wistar; Synaptophysin; Vimentin | 1992 |
N-ethyl-N-nitrosourea induced brain tumors in rats monitored by nuclear magnetic resonance imaging, plasma proton nuclear magnetic resonance spectroscopy and microscopy.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Microscopy; Rats; Rats, Inbred F344 | 1992 |
High susceptibility of analbuminemic rats to neurogenic tumor induction by transplacental administration of N-ethyl-N-nitrosourea.
Topics: Animals; Brain Neoplasms; Disease Susceptibility; DNA, Neoplasm; Ethylnitrosourea; Female; Guanine; Injections, Subcutaneous; Male; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1992 |
A preliminary investigation of promotion of brain tumours by hexachlorophane in Sprague-Dawley rats transplacentally exposed to N-ethylnitrosourea.
Topics: Animals; Body Weight; Brain; Brain Edema; Brain Neoplasms; Carcinogens; Cocarcinogenesis; Eating; Ethylnitrosourea; Female; Hexachlorophene; Maternal-Fetal Exchange; Organ Size; Pregnancy; Rats; Rats, Inbred Strains | 1992 |
Immunohistochemical recognition of ethylnitrosourea induced rat brain microtumors by anti-Leu 7 monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation; Brain Neoplasms; CD57 Antigens; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Immunohistochemistry; Oligodendroglioma; Rats; Rats, Inbred Strains | 1990 |
Cell proliferation in intracranial tumours: selective silver staining of nucleolar organizer regions (AgNORs). Application to surgical and experimental neuro-oncology.
Topics: Animals; Brain Neoplasms; Cell Division; Ethylnitrosourea; Humans; Image Processing, Computer-Assisted; Nervous System Neoplasms; Nucleolus Organizer Region; Rats; Silver; Staining and Labeling; Stereotaxic Techniques | 1991 |
Experimental CNS tumors in rats. Testing field for a computerized classification and tumor grading.
Topics: Animals; Brain Neoplasms; Diagnosis, Computer-Assisted; Ethylnitrosourea; Rats; Rats, Inbred Strains | 1991 |
Regional distribution study of brain perfusion and metabolic agents in normal and tumour bearing rat brains using autoradiographic technique.
Topics: Amphetamines; Animals; Autoradiography; Brain; Brain Chemistry; Brain Neoplasms; Ethylnitrosourea; Female; Glucose; Iodine Radioisotopes; Iodobenzenes; Iofetamine; Methionine; Neoplasms, Experimental; Perfusion; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Immunohistochemical investigations in experimentally induced tumors of the nervous system.
Topics: Animals; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Intermediate Filament Proteins; Neurofilament Proteins; Peripheral Nervous System Neoplasms; Pregnancy; Rats; Spinal Cord Neoplasms; Survival Rate; Vimentin | 1990 |
The effects of X-irradiation, N-ethyl-N-nitrosourea or combined treatment on O6-alkylguanine-DNA alkyltransferase activity in fetal rat brain and liver and the induction of CNS tumours.
Topics: Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Fetus; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred Strains; X-Rays | 1990 |
Diaplacental induction by ethylnitrosourea of tumours at the pial border of the central nervous system in (T X HT)F1 mice.
Topics: Animals; Brain Neoplasms; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Fetal Diseases; Fetus; Male; Maternal-Fetal Exchange; Meninges; Mice; Peripheral Nervous System Neoplasms; Pregnancy; Skull Neoplasms | 1990 |
[Synthesis and animal experiments of ethylnitrosourea].
Topics: Animals; Brain Neoplasms; Cranial Nerve Neoplasms; Ethylnitrosourea; Female; Glioma; Pregnancy; Rats; Rats, Inbred Strains; Trigeminal Nerve | 1990 |
Glial fibrillary acidic protein and vimentin in the experimental glial reaction of the rat brain.
Topics: Animals; Astrocytes; Brain; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Lasers; Nerve Crush; Pregnancy; Rats; Rats, Inbred F344; Staining and Labeling; Vimentin | 1986 |
Expression of vimentin and glial fibrillary acidic protein in ethylnitrosourea-induced rat gliomas and glioma cell lines.
Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Line, Transformed; Epitopes; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioma; Intermediate Filaments; Neoplasm Transplantation; Nerve Tissue; Rats; Tumor Cells, Cultured; Vimentin | 1989 |
[Differences in microvasculature between ethylnitrosourea-induced brain tumor and transplanted 9L cell brain tumor in the rat].
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Microcirculation; Microscopy, Electron; Neoplasm Transplantation; Rats; Rats, Inbred F344; Rats, Inbred Strains; Tumor Cells, Cultured | 1989 |
Comparative transplacental carcinogenesis by directly acting and metabolism-dependent alkylating agents in rodents and nonhuman primates.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Carcinogens; Choriocarcinoma; Diethylnitrosamine; Erythrocebus patas; Ethylnitrosourea; Female; Male; Neoplasms, Experimental; Neoplasms, Germ Cell and Embryonal; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Uterine Neoplasms | 1989 |
N-ras mutation in chemically induced rat brain tumour.
Topics: Animals; Blotting, Southern; Brain Neoplasms; DNA Probes; DNA, Neoplasm; Electrophoresis, Agar Gel; Ethylnitrosourea; Genes, ras; Mutation; Polymorphism, Restriction Fragment Length; Rats; Rats, Inbred F344 | 1989 |
Glomeruloid blood vessels in ethylnitrosourea-induced rat gliomas. Histological and immunohistochemical studies.
Topics: Animals; Blood Vessels; Brain Neoplasms; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Glioma; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; von Willebrand Factor | 1989 |
A comparison of the effect of several factors on the plasminogen activator activity of cloned lines from an ethylnitrosourea-induced glioma and from normal tissue.
Topics: Animals; Brain Neoplasms; Cell Line; Cholera Toxin; Colforsin; Dexamethasone; Epidermal Growth Factor; Ethylnitrosourea; Glioma; Plasminogen Activators; Rats | 1989 |
Immunocytochemical alpha-1-antichymotrypsin localization in the experimental brain tumors and at their periphery.
Topics: alpha 1-Antichymotrypsin; Animals; Astrocytoma; Biomarkers, Tumor; Brain; Brain Neoplasms; Ethylnitrosourea; Immunoenzyme Techniques; Oligodendroglioma; Rats; Rats, Inbred Strains | 1989 |
Effect of chronic stress on ENU-induced tumors.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Pregnancy; Rats; Stress, Psychological | 1989 |
Cell-specific brain tumour induction in neural transplants: evidence for multistep carcinogenesis in the nervous system.
Topics: Animals; Brain; Brain Neoplasms; Carcinogens; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Nerve Tissue; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred F344 | 1989 |
A sequential ultrastructural and histoautoradiographic study of early neoplastic lesions in ethylnitrosourea-induced rat glioma.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Transformation, Neoplastic; Ethylnitrosourea; Female; Glioma; Hyperplasia; Male; Microscopy, Electron; Neurons; Rats; Rats, Inbred Strains | 1989 |
Cloned neoplastic cells from a chemically-induced rat glioma: immunocytochemical characterization.
Topics: Animals; Astrocytes; Brain Neoplasms; Clone Cells; Ethylnitrosourea; Fibronectins; Fluorescent Antibody Technique; Glial Fibrillary Acidic Protein; Glioma; Glutamate-Ammonia Ligase; Rats; Vimentin | 1985 |
Correlations between the degree and type of forebrain malformations and the simultaneous neuro-oncogenic properties of ethylnitrosourea after diaplacental exposure in rats, alone and in combination with X-irradiation.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1985 |
Immunohistochemical studies on cellular character of microtumors induced by ethylnitrosourea in the rat brain utilizing anti-Leu 7 and anti-glial fibrillary acidic protein antibodies.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Histocytochemistry; Immunochemistry; Neoplasms, Germ Cell and Embryonal; Oligodendroglioma; Pregnancy; Rats; Rats, Inbred Strains | 1985 |
DNA cross-linking responses of human malignant glioma cell strains to chloroethylnitrosoureas, cisplatin, and diaziquone.
Topics: Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cells, Cultured; Cisplatin; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Drug Resistance; Ethylnitrosourea; Glioblastoma; Humans; Neoplasm Proteins; Nitrosourea Compounds | 1987 |
The effect of dexamethasone on vascular permeability of experimental brain tumours.
Topics: Animals; Brain Neoplasms; Capillary Permeability; Carbon Radioisotopes; Dexamethasone; Ethylnitrosourea; Female; Glioma; Kinetics; Male; Mannitol; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1986 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on neurogenic microtumors initiated by transplacental exposure to N-ethyl-N-nitrosourea.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cocarcinogenesis; Ependymoma; Ethylnitrosourea; Female; Glioma; Male; Maternal-Fetal Exchange; Oligodendroglioma; Placenta; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1987 |
Establishment and characterization of an intracerebrally transplanted tumor line, induced experimentally in the spinal cord.
Topics: Animals; Brain Neoplasms; Cell Line; Ethylnitrosourea; Female; Neoplasm Transplantation; Nervous System Neoplasms; Pregnancy; Rats; Rats, Inbred Strains; Spinal Cord Neoplasms | 1988 |
The intraneoplastic chemotherapy in a rat brain tumour model utilizing methotrexate-polymethylmethacrylate-pellets.
Topics: Animals; Brain Neoplasms; Drug Carriers; Drug Implants; Ethylnitrosourea; Glioma; Methotrexate; Methylmethacrylates; Rats; Stereotaxic Techniques | 1987 |
Capillary permeability and boron distribution in ethylnitrosourea-induced rat glioma.
Topics: Animals; Boron; Brain; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Evans Blue; Glioma; Horseradish Peroxidase; Isotopes; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Selective induction by N-nitrosoethylurea of oligodendrogliomas in fetal forebrain transplants.
Topics: Animals; Brain; Brain Neoplasms; Cell Differentiation; Cell Transformation, Neoplastic; DNA; Ethylnitrosourea; Female; Fetus; Nerve Tissue; Oligodendroglioma; Rats; Rats, Inbred F344 | 1988 |
Enzymatic elimination of O6-ethylguanine from the DNA of ethylnitrosourea-exposed normal and malignant rat brain cells grown under cell culture versus in vivo conditions.
Topics: Animals; Brain Neoplasms; DNA; DNA Repair; Ethylnitrosourea; Guanine; Kinetics; Rats; Tumor Cells, Cultured | 1988 |
Vascular permeability and cell kinetics of ethylnitrosourea (ENU)-induced rat brain tumours.
Topics: Animals; Brain Neoplasms; Capillary Permeability; Ethylnitrosourea; Glioma; Pharmacokinetics; Rats; Rats, Inbred Strains | 1988 |
Intermediate filaments and anaplastic change of ENU-induced gliomass: immunohistochemical study with vimentin and astroprotein (GFAP).
Topics: Anaplasia; Animals; Astrocytoma; Brain Neoplasms; Cytoskeleton; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Immunohistochemistry; Intermediate Filaments; Oligodendroglioma; Rats; Rats, Inbred Strains; Vimentin | 1987 |
Expression of c-sis and platelet-derived growth factor in in vitro-transformed glioma cells from rat brain tissue transplacentally treated with ethylnitrosourea.
Topics: Animals; Brain; Brain Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Genes; Glioma; Maternal-Fetal Exchange; Oncogenes; Platelet-Derived Growth Factor; Pregnancy; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-sis; Rats | 1986 |
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Carbamates; Carmustine; Cell Cycle; Cell Line; Cell Survival; Cross-Linking Reagents; Ethylnitrosourea; Lomustine; Nitroso Compounds; Nitrosourea Compounds; Rats; Structure-Activity Relationship | 1986 |
Promoting effect of 12-O-tetradecanoylphorbol-13-acetate on the in vitro malignant transformation of fetal rat brain cells exposed in utero to ethylnitrosourea.
Topics: Animals; Brain Neoplasms; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Concanavalin A; Ethylnitrosourea; Female; Glial Fibrillary Acidic Protein; Maternal-Fetal Exchange; Neoplasm Transplantation; Neoplastic Stem Cells; Phorbols; Pregnancy; Rats; Tetradecanoylphorbol Acetate | 1986 |
Chemotherapy in intracerebrally transplanted tumors induced with transplacental administration of ethylnitrosourea in rats.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ethylnitrosourea; Female; Lomustine; Methylnitrosourea; Neoplasm Transplantation; Placenta; Pregnancy; Rats; Spinal Cord Neoplasms | 1986 |
Comparison of sister-chromatid exchange induction caused by nitrosoureas that alkylate or alkylate and crosslink DNA.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Cells, Cultured; Cross-Linking Reagents; DNA; Ethylnitrosourea; Nimustine; Nitrosourea Compounds; Rats; Sister Chromatid Exchange | 1985 |
Induction of gliomas in Mongolian gerbils (Meriones unguiculatus) following neonatal administration of N-ethyl-N-nitrosourea.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Ethylnitrosourea; Female; Gerbillinae; Glioma; Hemangioma; Kidney Neoplasms; Male; Melanoma; Nitrosourea Compounds; Odontogenic Tumors; Skin Neoplasms; Spinal Cord Neoplasms | 1985 |
Morphological maturation of tumor cells induced by ethylnitrosourea (ENU) in rat brains. II. On the tumors by administration of ENU in the mid-gestational stage.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; Astrocytoma; Brain Neoplasms; Cell Differentiation; DNA Replication; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1985 |
Morphological maturation of tumor cells induced by ethylnitrosourea (ENU) in rat brains. I. On the tumors by administration of ENU in the late gestational stage.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antigens, Surface; Astrocytoma; Brain Neoplasms; Ethylnitrosourea; Female; Gestational Age; Glial Fibrillary Acidic Protein; Glioma; Oligodendroglioma; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains | 1985 |
Current brain tumour models with particular consideration of the transplantation techniques. Outline of literature and personal preliminary results.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Glioma; Graft Survival; Intracranial Pressure; Male; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1986 |
The brain-tumour issue in long-term toxicity studies in rats.
Topics: Age Factors; Animal Diseases; Animals; Brain; Brain Neoplasms; Carcinogens; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylnitrosourea; Rats; Research Design; Time Factors | 1986 |
Similar carcinogenic effects in rats of 1-ethyl-1-nitroso-3-hydroxyethylurea and 1-hydroxyethyl-1-nitroso-3-ethylurea.
Topics: Animals; Brain Neoplasms; Carcinogens; Ethylnitrosourea; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344 | 1985 |
Organ-specific carcinogenicity of N-methyl-N-nitrosourea in F344 and ACI/N rats.
Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Organ Specificity; Rats; Rats, Inbred ACI; Rats, Inbred F344; Species Specificity; Spinal Cord Neoplasms | 1985 |
Differentiation markers (S-100, GFAP, NSE and D2) in fetal rat brain cells during malignant transformation in cell culture.
Topics: Animals; Antigens, Surface; Brain; Brain Chemistry; Brain Neoplasms; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Cells, Cultured; Ethylnitrosourea; Female; Fetus; Glial Fibrillary Acidic Protein; Nerve Tissue Proteins; Phosphopyruvate Hydratase; Pregnancy; Rats; Rats, Inbred Strains; S100 Proteins | 1985 |
[Structural changes in the CNS after prenatal radiation exposure and their significance for regenerative and neoplastic processes].
Topics: Animals; Brain; Brain Neoplasms; Cell Division; DNA; Dose-Response Relationship, Radiation; Ethylnitrosourea; Mice; Necrosis; Neoplasms, Radiation-Induced; Rats; Regeneration | 1985 |
[Immunohistochemical study of ethylnitrosourea-induced rat gliomas with vimentin and astroprotein (GFAP)].
Topics: Animals; Brain Chemistry; Brain Neoplasms; Ethylnitrosourea; Glial Fibrillary Acidic Protein; Glioma; Histocytochemistry; Rats; Rats, Inbred Strains; Vimentin | 1985 |
[Lysosomal enzymes in nitrosamine induced nervous system tumors of rats (author's transl)].
Topics: Acid Phosphatase; Animals; Brain; Brain Neoplasms; Ethylnitrosourea; Female; Glioma; Glucuronidase; Hexosaminidases; Lysosomes; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Oligodendroglioma; Pregnancy; Rats; Sulfatases | 1974 |