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ethylnitrosourea and Abnormalities, Drug-Induced

ethylnitrosourea has been researched along with Abnormalities, Drug-Induced in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199016 (57.14)18.7374
1990's8 (28.57)18.2507
2000's3 (10.71)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aleshin, AE; Golubkov, VS; Strongin, AY1
Hata, S; Nomura, T; Shibata, K1
Adamczewska-Goncerzewicz, Z; Mularek, O; Wender, M; Zórawski, A1
Fujiwara, H1
Faustman, EM; Seeley, MR1
Nagao, T; Sato, M; Takashima, H; Wada, A1
Imai, K; Marumo, H; Nagao, T; Sato, M; Shibuya, T1
Fujikawa, K; Nagao, T2
Bergstrom, RA; Browning, VL; John, SW; Libby, B; Munroe, RJ; Schimenti, JC; Schimenti, KJ; Smith, R; Zheng, QY1
Doi, K; Ishigami, N; Katayama, K; Kiatipattanasakul, W; Nakayama, H; Ohtsuka, R; Suzuki, M1
Hayashi, S; Kakita, A; Kawasaki, K; Oyanagi, K; Yamada, M1
Fujiwara, K; Matsumoto, S; Oi, Y; Tamaki, N; Taomoto, K1
Kageyama, N; Kameyama, Y; Kobayashi, T; Umemura, S; Yoshida, J1
Alexandrov, VA1
Berg, H; Graw, J; Ivankovic, S; Schmähl, D1
Catalano, A; Huang, PH1
Gotoh, H; Namba, T; Nomura, T1
Johnson, FM; Lovell, DP; Snell, ML1
Nomura, T1
Ohnishi, M1
Kriegel, H; Schmahl, W1
Ehling, UH; Favor, J; Neuhäuser-Klaus, A1
Cain, KT; Downing, DJ; Generoso, WM; Hughes, LA; Rutledge, JC1
Lyon, MF; Renshaw, R1
Hung, CF1
Johnson, FM; Lovell, DP; Willis, DB1
Carpenter, DA; Hitotsumachi, S; Russell, WL1

Reviews

1 review(s) available for ethylnitrosourea and Abnormalities, Drug-Induced

ArticleYear
Congenital malformations as a consequence of parental exposure to radiation and chemicals in mice.
    Journal of UOEH, 1989, Mar-20, Volume: 11 Suppl

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Dioxins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethylnitrosourea; Fathers; Female; Gestational Age; Humans; Male; Mice; Mice, Inbred ICR; Mutation; Oocytes; Pregnancy; Prenatal Exposure Delayed Effects; Spermatozoa; Urethane; Vietnam

1989

Other Studies

27 other study(ies) available for ethylnitrosourea and Abnormalities, Drug-Induced

ArticleYear
Potential relation of aberrant proteolysis of human protein tyrosine kinase 7 (PTK7) chuzhoi by membrane type 1 matrix metalloproteinase (MT1-MMP) to congenital defects.
    The Journal of biological chemistry, 2011, Jun-10, Volume: 286, Issue:23

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Shape; Ethylnitrosourea; Humans; Matrix Metalloproteinase 14; Mice; Mutation; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases

2011
A method to detect tumors and presumed somatic mutations in mice.
    Cancer letters, 1983, Volume: 18, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Ethylnitrosourea; Female; Gestational Age; Male; Mice; Mutagenicity Tests; Mutation; Neoplasms, Experimental; Nitrosourea Compounds; Urethane

1983
The fatty acid pattern of central myelin lipids after transplacental intoxication by ethylnitrosourea.
    Experimental pathology, 1981, Volume: 19, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Central Nervous System; Ethylnitrosourea; Fatty Acids; Female; Lipid Metabolism; Maternal-Fetal Exchange; Metabolism, Inborn Errors; Mice; Myelin Sheath; Nitrosourea Compounds; Pregnancy

1981
Cytotoxic effects of ethylnitrosourea on central nervous system of rat embryos. Special references to carcinogenesis and teratogenesis.
    Acta pathologica japonica, 1980, Volume: 30, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Brain Neoplasms; Cerebral Ventricles; DNA; Embryo, Mammalian; Ethylnitrosourea; Female; Microcephaly; Mitosis; Necrosis; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rosette Formation; Telencephalon

1980
Toxicity of four alkylating agents on in vitro rat embryo differentiation and development.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 26, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Cells, Cultured; Central Nervous System; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Forelimb; Methyl Methanesulfonate; Methylnitrosourea; Rats

1995
Congenital malformations in the offspring of male mice treated with ethylnitrosourea at the embryonic stage.
    Teratogenesis, carcinogenesis, and mutagenesis, 1994, Volume: 14, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Embryonic and Fetal Development; Ethylnitrosourea; Female; Male; Mice; Mice, Inbred ICR; Pregnancy; Prenatal Exposure Delayed Effects

1994
Testicular development and fertility of mice treated prenatally with N-nitroso-N-ethylurea at various gestational stages.
    Teratogenesis, carcinogenesis, and mutagenesis, 1996, Volume: 16, Issue:3

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Body Weight; Ethylnitrosourea; Female; Fertility; Gestational Age; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred ICR; Organ Size; Pregnancy; Teratogens; Testis

1996
Male-mediated teratogenesis: spectrum of congenital malformations in the offspring of A/J male mice treated with ethylnitrosourea.
    Teratogenesis, carcinogenesis, and mutagenesis, 1996, Volume: 16, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Cleft Palate; Ethylnitrosourea; Fathers; Female; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Paternal Exposure; Pregnancy; Teratogens; Testis

1996
Mouse mutants from chemically mutagenized embryonic stem cells.
    Nature genetics, 2000, Volume: 24, Issue:3

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Bone and Bones; Chimera; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Genes, Lethal; Hypoxanthine Phosphoribosyltransferase; Limb Deformities, Congenital; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutagenesis; Mutagens; Point Mutation; Retina; RNA Splicing; Stem Cells; Testis

2000
Teratologic studies on rat perinates and offspring from dams treated with ethylnitrosourea (ENU).
    Experimental animals, 2000, Volume: 49, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Apoptosis; Body Weight; Cerebral Cortex; Ethylnitrosourea; Female; Fetal Growth Retardation; Fetal Weight; Forelimb; Organ Size; Pregnancy; Rats; Rats, Inbred F344; Tail; Teratogens; Toxicity Tests

2000
Expression of calbindin D-28k and parvalbumin in cerebral cortical dysgenesis induced by administration of ethylnitrosourea to rats at the stage of neurogenesis.
    Acta neuropathologica, 2001, Volume: 101, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Brain Chemistry; Calbindins; Cell Size; DNA Replication; Ethylnitrosourea; Female; Gene Expression Regulation, Developmental; Gestational Age; Male; Morphogenesis; Neocortex; Nerve Tissue Proteins; Neurons; Parvalbumins; Rats; Rats, Wistar; S100 Calcium Binding Protein G

2001
[Experimental study of the central nervous system malformations. Mechanism of the neural tube malformations induced by ethylnitrosourea administration at the stage of embryogenesis (author's transl)].
    Neurologia medico-chirurgica, 1977, Volume: 17, Issue:5 Pt 2

    Topics: Abnormalities, Drug-Induced; Animals; Central Nervous System; Ethylnitrosourea; Gestational Age; Nitrosourea Compounds; Rats

1977
[Effect of irradiation to carcinogenesis by transplacental ethylnitrosourea in BD--IX rat (author's transl)].
    No to shinkei = Brain and nerve, 1978, Volume: 30, Issue:12

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain Neoplasms; Cerebral Cortex; Embryo, Mammalian; Ethylnitrosourea; Female; Glioma; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Neurilemmoma; Nitrosourea Compounds; Peripheral Nervous System Neoplasms; Pregnancy; Rats

1978
Some results and prospects of transplacental carcinogenesis studies.
    Neoplasma, 1976, Volume: 23, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Drug-Induced; Animals; Brain; Brain Neoplasms; Disease Models, Animal; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Methylnitrosourea; Neoplasms, Experimental; Nervous System Diseases; Nitrosourea Compounds; Organ Specificity; Placenta; Pregnancy; Rats

1976
[Teratogenic action of ethyl-nitrosourea in Göttingen miniature pigs (author's transl)].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Abnormalities, Drug-Induced; Animals; Bone Development; Ethylnitrosourea; Female; Forelimb; Gestational Age; Maxilla; Nitrosourea Compounds; Pregnancy; Spine; Swine; Teratogens

1975
N-alkyl-N-nitrosourea induced secondary structural changes in DNA from rat embryos and fetal brains in vivo.
    Teratogenesis, carcinogenesis, and mutagenesis, 1992, Volume: 12, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Brain; DNA; Embryo, Mammalian; Ethylnitrosourea; Female; Fetus; Methylnitrosourea; Neoplasms, Experimental; Nucleic Acid Conformation; Pregnancy; Rats; Rats, Wistar

1992
Genotoxic potency in mouse spermatogonial stem cells of triethylenemelamine, mitomycin C, ethylnitrosourea, procarbazine, and propyl methanesulfonate as measured by F1 congenital defects.
    Mutation research, 1990, Volume: 229, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Ethylnitrosourea; Male; Mesylates; Mice; Mice, Inbred ICR; Mitomycin; Mitomycins; Mutagenicity Tests; Procarbazine; Spermatogonia; Spermatozoa; Stem Cells; Triethylenemelamine

1990
An examination of respiratory distress and chromosomal abnormalities in the offspring of male mice treated with ethylnitrosourea.
    Mutation research, 1990, Volume: 229, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Chromosome Aberrations; Ethylnitrosourea; Karyotyping; Male; Mice; Mice, Inbred ICR; Mutation; Respiratory Insufficiency; Spermatogonia; Spermatozoa

1990
High resolution metrical analysis applied to the assessment of damage associated with induced mutations in the mouse.
    Mutation research, 1990, Volume: 229, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Biometry; Bone and Bones; Ethylnitrosourea; Female; Litter Size; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mutagenicity Tests

1990
Craniofacial malformations induced by N-ethyl-N-nitrosourea in rat embryos in vivo and in vitro.
    The Kobe journal of medical sciences, 1989, Volume: 35, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Ethylnitrosourea; Facial Bones; Female; In Vitro Techniques; Pregnancy; Rats; Rats, Inbred Strains; Skull; Teratogens

1989
Correlations between the degree and type of forebrain malformations and the simultaneous neuro-oncogenic properties of ethylnitrosourea after diaplacental exposure in rats, alone and in combination with X-irradiation.
    Teratogenesis, carcinogenesis, and mutagenesis, 1985, Volume: 5, Issue:3

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Brain; Brain Neoplasms; Dose-Response Relationship, Radiation; Ethylnitrosourea; Female; Glioma; Maternal-Fetal Exchange; Neoplasms, Radiation-Induced; Pregnancy; Rats; Rats, Inbred Strains; Teratogens

1985
The effect of dose fractionation on the frequency of ethylnitrosourea-induced dominant cataract and recessive specific locus mutations in germ cells of the mouse.
    Mutation research, 1988, Volume: 198, Issue:2

    Topics: Abnormalities, Drug-Induced; Alleles; Animals; Cataract; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Genes, Dominant; Genes, Recessive; Male; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Spermatogonia

1988
Mutagen-induced fetal anomalies and death following treatment of females within hours after mating.
    Mutation research, 1988, Volume: 199, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Cleavage Stage, Ovum; Embryo Implantation; Ethyl Methanesulfonate; Ethylene Oxide; Ethylnitrosourea; Female; Fetal Death; Mice; Mutagens; Oocytes; Ovum; Pregnancy; Triethylenemelamine; Zygote

1988
Induction of congenital malformations in the offspring of mutagen treated mice.
    Progress in clinical and biological research, 1986, Volume: 209B

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Mice; Mice, Inbred C3H; Mutagens; Pregnancy; Prenatal Exposure Delayed Effects

1986
The relationship between hydrocephalus and Chiari type II malformation in the experimental rat fetuses with Arnold-Chiari malformation.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1986, Volume: 10, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Arnold-Chiari Malformation; Brain; Ethylnitrosourea; Female; Fetus; Hydrocephalus; Male; Neural Tube Defects; Pregnancy; Rats; Rats, Inbred Strains

1986
Lack of evidence for skeletal abnormalities in offspring of mice exposed to ethylnitrosourea.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:9

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Ethylnitrosourea; Female; Genetic Variation; Male; Mice; Mice, Inbred Strains; Mutation; Nitrosourea Compounds; Phenotype; Pregnancy

1985
Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:19

    Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Ethylnitrosourea; Female; Infertility, Male; Male; Mice; Mutagens; Mutation; Pregnancy; Spermatogonia; Spermatozoa; Stem Cells; Time Factors

1985