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ethylmaleimide and Thalassemia

ethylmaleimide has been researched along with Thalassemia in 4 studies

Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.

Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.

Research Excerpts

ExcerptRelevanceReference
"beta-Thalassemia is an inherited human disorder which is characterized by a deficient production of hemoglobin beta chains and an attendant accumulation of structurally normal alpha chains in the erythropoietic cells."1.27ATP-dependent proteolysis of hemoglobin alpha chains in beta-thalassemic hemolysates is ubiquitin-dependent. ( Shaeffer, JR, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jewell, AP1
Marcus, RE1
Rouyer-Fessard, P1
Garel, MC1
Domenget, C1
Guetarni, D1
Bachir, D1
Colonna, P1
Beuzard, Y1
Shaeffer, JR1
Neer, EJ1

Other Studies

4 other studies available for ethylmaleimide and Thalassemia

ArticleYear
Platelet derived malonyldialdehyde production in patients with thalassaemia major.
    Journal of clinical pathology, 1984, Volume: 37, Issue:9

    Topics: Adolescent; Adult; Blood Platelets; Ethylmaleimide; Ferritins; Humans; Hydrogen Peroxide; In Vitro T

1984
A study of membrane protein defects and alpha hemoglobin chains of red blood cells in human beta thalassemia.
    The Journal of biological chemistry, 1989, Nov-15, Volume: 264, Issue:32

    Topics: Erythrocyte Membrane; Ethylmaleimide; Genetic Carrier Screening; Hemoglobin A; Homozygote; Humans; M

1989
ATP-dependent proteolysis of hemoglobin alpha chains in beta-thalassemic hemolysates is ubiquitin-dependent.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Adenosine Triphosphate; Antibodies; Cell-Free System; Ethylmaleimide; Globins; Hemoglobins; Humans;

1988
The reactions of the sulfhydryl groups of human hemoglobin beta 4.
    The Journal of biological chemistry, 1970, Feb-10, Volume: 245, Issue:3

    Topics: Alkylation; Carbon Isotopes; Carbon Monoxide; Chemical Phenomena; Chemistry; Ethylmaleimide; Hemoglo

1970