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ethylmaleimide and Pheochromocytoma

ethylmaleimide has been researched along with Pheochromocytoma in 5 studies

Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"Rat pheochromocytoma PC 12 cell membranes were shown to possess A2-like adenosine binding sites as assessed by using 5'-N-ethylcarboxamide[3H]adenosine [( 3H]NECA)."7.67Adenosine binding sites of rat pheochromocytoma PC 12 cell membranes: partial characterization and solubilization. ( Fujisawa, H; Nakata, H, 1988)
"The effect of the hydrolysis-resistant GTP analogs, guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) and guanylyl imidodiphosphate (GMPPNP), on norepinephrine (NE) secretion from digitonin-permeabilized rat pheochromocytoma cells, PC12, was examined."3.68Hydrolysis-resistant GTP analogs stimulate catecholamine release from digitonin-permeabilized PC12 cells. ( Carroll, AG; Rhoads, AR; Wagner, PD, 1990)
"Rat pheochromocytoma PC 12 cell membranes were shown to possess A2-like adenosine binding sites as assessed by using 5'-N-ethylcarboxamide[3H]adenosine [( 3H]NECA)."3.67Adenosine binding sites of rat pheochromocytoma PC 12 cell membranes: partial characterization and solubilization. ( Fujisawa, H; Nakata, H, 1988)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leprince, P1
Carroll, AG1
Rhoads, AR1
Wagner, PD1
Ahnert-Hilger, G1
Gratzl, M1
Schömig, E1
Michael-Hepp, J1
Bönisch, H1
Nakata, H1
Fujisawa, H1

Other Studies

5 other studies available for ethylmaleimide and Pheochromocytoma

ArticleYear
Chemical modification of the nicotinic cholinergic receptor of PC-12 nerve cell.
    Biochemistry, 1983, Nov-22, Volume: 22, Issue:24

    Topics: Acetylcholine; Adrenal Gland Neoplasms; Affinity Labels; Animals; Cell Line; Dithionitrobenzoic Acid

1983
Hydrolysis-resistant GTP analogs stimulate catecholamine release from digitonin-permeabilized PC12 cells.
    Journal of neurochemistry, 1990, Volume: 55, Issue:3

    Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Cell Membrane Permeability; Digit

1990
Further characterization of dopamine release by permeabilized PC12 cells.
    Journal of neurochemistry, 1987, Volume: 49, Issue:3

    Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Chlorides; Culture Med

1987
Inhibition of neuronal noradrenaline uptake (uptake1) and desipramine binding by N-ethylmaleimide (NEM).
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:6

    Topics: Adrenal Gland Neoplasms; Animals; Cell Membrane; Cells, Cultured; Cocaine; Desipramine; Ethylmaleimi

1988
Adenosine binding sites of rat pheochromocytoma PC 12 cell membranes: partial characterization and solubilization.
    Journal of biochemistry, 1988, Volume: 104, Issue:3

    Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Binding Sites; Cell Membrane; Chromatography, Gel; Ethy

1988