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ethylmaleimide and Gastric Ulcer

ethylmaleimide has been researched along with Gastric Ulcer in 27 studies

Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with indomethacin to suppress endogenous PG reversed completely the protective and hyperemic effects of SU-840 against ethanol and stress induced damage whereas L-NNA, a potent inhibitor of NO-synthase, failed to affect protection but completely abolished the hyperemia evoked by this agent."1.30SU-840, a novel synthetic flavonoid derivative of sophoradin, with potent gastroprotective and ulcer healing activity. ( Brzozowski, T; Drozdowicz, D; Konturek, SJ; Kwiecien, S; Muramatsu, M; Pajdo, R; Sliwowski, Z, 1998)
"Pretreatment with indomethacin (IND) had little influence on the cytoprotective effects of OGT and glutathione, but attenuated the effect of sucralfate."1.28A possible mechanism for the gastric mucosal protection by oren-gedoku-to (OGT), a traditional herbal medicine. ( Imanishi, K; Miura, O; Takase, H; Yumioka, E, 1989)
"pretreatment with indomethacin (5 mg/kg, s."1.27Cytoprotective effects of NC-1300 and omeprazole on Hcl . ethanol-induced gastric lesions in rats. ( Awane, Y; Miyake, H; Okabe, S, 1986)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's6 (22.22)18.2507
2000's7 (25.93)29.6817
2010's6 (22.22)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Parra, T1
Benites, J1
Ruiz, LM1
Sepulveda, B2
Simirgiotis, M2
Areche, C2
Quispe, C1
Torres-Benítez, A1
Reyes-Ortíz, J1
García-Beltrán, O1
Biano, LS1
Oliveira, AS1
Palmeira, DN1
Silva, LA1
de Albuquerque-Junior, RLC1
Duarte, MC1
Correa, CB1
Grespan, R1
Batista, JS1
Camargo, EA1
Antonisamy, P1
Arasu, MV1
Dhanasekaran, M1
Choi, KC1
Aravinthan, A1
Kim, NS1
Kang, CW1
Kim, JH1
Hiruma-Lima, CA4
Rodrigues, CM1
Kushima, H1
Moraes, TM1
Lolis, Sde F1
Feitosa, SB1
Magri, LP1
Soares, FR1
Cola, MM1
Andrade, FD1
Vilegas, W4
Souza Brito, AR3
Gomes, Rde C1
Bonamin, F1
Darin, DD1
Seito, LN1
Di Stasi, LC1
Dokkedal, AL1
Sánchez-Mendoza, ME2
Reyes-Trejo, B1
Sánchez-Gómez, P1
Rodríguez-Silverio, J1
Castillo-Henkel, C1
Cervantes-Cuevas, H1
Arrieta, J2
Castro, GA1
Carvalho, JE1
Tinti, SV1
Possenti, A2
Sgarbieri, VC1
Vera-Arzave, C1
Antonio, LC1
Cruz-Hernández, G1
Velasquez-Mendez, AM1
Reyes-Ramírez, A1
Lima, ZP1
Severi, JA1
Pellizzon, CH1
Brito, AR1
Solis, PN1
Cáceres, A1
Girón, LM1
Andreo, MA1
Ballesteros, KV1
Machado da Rocha, LR1
Gürbüz, I1
Yesilada, E1
Gyires, K1
López, A1
Motilva, V1
Alarcón de la Lastra, C1
Martín, MJ1
La Casa, C1
Brzozowski, T2
Konturek, SJ2
Kwiecien, S1
Pajdo, R1
Drozdowicz, D1
Sliwowski, Z1
Muramatsu, M1
Maity, S1
Vedasiromoni, JR1
Chaudhuri, L1
Ganguly, DK1
Dias, PC1
Foglio, MA1
Nogueira, DC1
de Carvalho, JE1
Cho, CH4
Pfeiffer, CJ1
Misra, HP1
Garg, GP1
Ogle, CW3
Konturek, PK1
Dembiński, A1
Poon, YK1
Ezer, E2
Takase, H1
Imanishi, K1
Miura, O1
Yumioka, E1
Fong, LY1
Wong, SH1
Dupuy, D1
Szabo, S1
Okabe, S1
Miyake, H1
Awane, Y1

Other Studies

27 other studies available for ethylmaleimide and Gastric Ulcer

ArticleYear
Gastroprotective activity of ent-beyerene derivatives in mice: Effects on gastric secretion, endogenous prostaglandins and non-protein sulfhydryls.
    Bioorganic & medicinal chemistry letters, 2015, Jul-15, Volume: 25, Issue:14

    Topics: Abietanes; Animals; Anti-Ulcer Agents; Baccharis; Cell Line; Cell Survival; Gastric Juice; Gastric M

2015
Gastroprotective activity of synthetic coumarins: Role of endogenous prostaglandins, nitric oxide, non-protein sulfhydryls and vanilloid receptors.
    Bioorganic & medicinal chemistry letters, 2016, 12-01, Volume: 26, Issue:23

    Topics: Animals; Anti-Ulcer Agents; Coumarins; Gastric Mucosa; Mice; Nitric Oxide; Prostaglandins; Stomach U

2016
Gastroprotective action of the ethanol extract of Leonurus sibiricus L. (Lamiaceae) in mice.
    Journal of ethnopharmacology, 2022, Feb-10, Volume: 284

    Topics: Animals; Enzyme Inhibitors; Ethanol; Ethylmaleimide; Gene Expression Regulation; Glyburide; Hypoglyc

2022
Protective effects of trigonelline against indomethacin-induced gastric ulcer in rats and potential underlying mechanisms.
    Food & function, 2016, Volume: 7, Issue:1

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Ethylmaleimide; Glyb

2016
The anti-ulcerogenic effects of Curatella americana L.
    Journal of ethnopharmacology, 2009, Jan-30, Volume: 121, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Dilleniaceae; Dinoprostone; Ethylmaleimide; Gastric Mucosa; Gastrins; Ho

2009
Antioxidative action of methanolic extract and buthanolic fraction of Vochysia tucanorum Mart. in the gastroprotection.
    Journal of ethnopharmacology, 2009, Jan-30, Volume: 121, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Brazil; Ethylmaleimide; Gastric Mucosa; Lipid Peroxidation

2009
Bioassay-guided isolation of an anti-ulcer chromene from Eupatorium aschenbornianum: role of nitric oxide, prostaglandins and sulfydryls.
    Fitoterapia, 2010, Volume: 81, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Benzopyrans; Carbenoxolone; Drug Evaluation, Preclinical; Ethanol; Ethyl

2010
Anti-ulcerogenic effect of a whey protein isolate and collagen hydrolysates against ethanol ulcerative lesions on oral administration to rats.
    Journal of medicinal food, 2010, Volume: 13, Issue:1

    Topics: Alkylation; Animals; Anti-Ulcer Agents; Carbenoxolone; Cattle; Collagen; Disease Models, Animal; Dru

2010
Gastroprotection of suaveolol, isolated from Hyptis suaveolens, against ethanol-induced gastric lesions in Wistar rats: role of prostaglandins, nitric oxide and sulfhydryls.
    Molecules (Basel, Switzerland), 2012, Jul-26, Volume: 17, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Carbenoxolone; Cyclooxygenase Inhibitors; Ethanol; Ethylmaleimide; Hypti

2012
Can the aqueous decoction of mango flowers be used as an antiulcer agent?
    Journal of ethnopharmacology, 2006, Jun-15, Volume: 106, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Ethanol; Ethylmaleimide; Flavonoids; Flowers;

2006
Effect of Mouriri pusa extracts on experimentally induced gastric lesions in rodents: role of endogenous sulfhydryls compounds and nitric oxide in gastroprotection.
    Journal of ethnopharmacology, 2006, Oct-11, Volume: 107, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Brazil; Enzyme Inhibitors; Etha

2006
Evaluation of the anti-ulcerogenic effect of sesquiterpene lactones from Centaurea solstitialis L. ssp. solstitialis by using various in vivo and biochemical techniques.
    Journal of ethnopharmacology, 2007, Jun-13, Volume: 112, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Behavior, Animal; Centaurea; Dose-Response Relationship, Drug; Enzyme In

2007
The role of endogenous nitric oxide in the gastroprotective action of morphine.
    European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3

    Topics: Animals; Anti-Ulcer Agents; Arginine; Aspirin; Cysteamine; Dinoprostone; Ethanol; Ethylmaleimide; Fe

1994
The role of gastric mucosal sulphydryls in the ulcer-protecting effects of cisapride.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cisapride; Disease Models, Animal; Ethanol; Ethylmaleimide; Gastric Muco

1996
SU-840, a novel synthetic flavonoid derivative of sophoradin, with potent gastroprotective and ulcer healing activity.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Ethylmaleimide; Female; Fl

1998
Role of reduced glutathione and nitric oxide in the black tea extract-mediated protection against ulcerogen-induced changes in motility and gastric emptying in rats.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:4

    Topics: Animals; Enzyme Inhibitors; Ethylmaleimide; Female; Gastric Emptying; Gastrointestinal Motility; Glu

2001
Antiulcerogenic activity of crude ethanol extract and some fractions obtained from aerial parts of Artemisia annua L.
    Phytotherapy research : PTR, 2001, Volume: 15, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Artemisia; Ethanol; Ethylmaleimide; Gas Chromatography-Mass Spectrometry

2001
Ulcerogenic mechanism of ethanol and the action of sulphanilyl fluoride on the rat stomach in-vivo.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:7

    Topics: Administration, Oral; Animals; Catalase; Ethanol; Ethylmaleimide; Female; Gastric Mucosa; Glucosepho

1991
N-ethylmaleimide antagonizes stress-induced gastric ulcers in rats.
    Experientia, 1991, Mar-15, Volume: 47, Issue:3

    Topics: Animals; Cold Temperature; Ethylmaleimide; Female; Immobilization; Rats; Rats, Inbred Strains; Stoma

1991
Role of epidermal growth factor, prostaglandin, and sulfhydryls in stress-induced gastric lesions.
    Gastroenterology, 1990, Volume: 99, Issue:6

    Topics: 16,16-Dimethylprostaglandin E2; Animals; DNA; Eflornithine; Epidermal Growth Factor; Ethylmaleimide;

1990
The protective mechanisms of paracetamol against ethanol-induced gastric mucosal damage in rats.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:8

    Topics: Acetaminophen; Administration, Oral; Animals; Ethanol; Ethylmaleimide; Injections, Subcutaneous; Mal

1989
Effect of cytoprotective and antiulcer drugs on the healing process of subacute gastric ulcer in rat (a new model).
    Acta physiologica Hungarica, 1989, Volume: 73, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Disease Models, Animal; Ethylma

1989
A possible mechanism for the gastric mucosal protection by oren-gedoku-to (OGT), a traditional herbal medicine.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Drugs, Chinese Herbal; Ethanol; Ethylmaleimide; Glutathione; Indomethaci

1989
Novel method for producing standard subacute gastric ulcer in rats and for the quantitative evaluation of the healing process. Effect of several drugs on healing.
    Journal of pharmacological methods, 1988, Volume: 20, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Disease

1988
Zinc deficiency worsens ethanol-induced gastric ulcers in rats.
    Drug-nutrient interactions, 1988, Volume: 5, Issue:4

    Topics: Acetylcysteine; Animals; Ethanol; Ethylmaleimide; Glutathione; Male; Rats; Rats, Inbred Strains; Sto

1988
Protection by metals against ethanol-induced gastric mucosal injury in the rat. Comparative biochemical and pharmacologic studies implicate protein sulfhydryls.
    Gastroenterology, 1986, Volume: 91, Issue:4

    Topics: Animals; Cadmium; Copper; Ethanol; Ethylmaleimide; Female; Gastric Acid; Gastric Mucosa; Indomethaci

1986
Cytoprotective effects of NC-1300 and omeprazole on Hcl . ethanol-induced gastric lesions in rats.
    Japanese journal of pharmacology, 1986, Volume: 42, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Ethanol; Ethylm

1986