ethylmaleimide has been researched along with Fanconi Anemia in 2 studies
Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| "N-Ethylmaleimide treatment abolishes multimerization and interaction of FANCA and FANCG in vitro." | 1.32 | Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. ( Beck, BD; Ciccone, SL; Clapp, DW; Freie, B; Hwang, B; Lee, SH; Park, SJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Voter, AF | 1 |
| Manthei, KA | 1 |
| Keck, JL | 1 |
| Park, SJ | 1 |
| Ciccone, SL | 1 |
| Beck, BD | 1 |
| Hwang, B | 1 |
| Freie, B | 1 |
| Clapp, DW | 1 |
| Lee, SH | 1 |
2 other studies available for ethylmaleimide and Fanconi Anemia
| Article | Year |
|---|---|
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
Topics: Antineoplastic Agents; DNA Damage; DNA Helicases; DNA Repair; Drug Screening Assays, Antitumor; Fanc | 2016 |
Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins.
Topics: Animals; Blotting, Western; Cloning, Molecular; COS Cells; Dimerization; Disulfides; DNA Damage; DNA | 2004 |