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ethylmaleimide and Experimental Neoplasms

ethylmaleimide has been researched along with Experimental Neoplasms in 24 studies

Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.

Research Excerpts

ExcerptRelevanceReference
"The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)."7.66Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980)
"Treatment of murine neuroblastoma N18 cells with N-ethylmaleimide under conditions that favor diminution of membrane potential leads to a 65% increase in the rate of veratridine-stimulated, tetrodotoxin-sensitive Na+ uptake and to a 50% decrease in the concentration of veratridine required for half-maximal stimulation."7.66Effects of N-ethylmaleimide treatment on the action potential Na+-ionophore of cultured neuroblastoma cells. ( Blumenthal, K; Panini, A, 1980)
"The beta-adrenergic receptor of C6 glioma cells contains a disulfide bridge which can be reduced by dithiothreitol (DTT)."3.66Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol. ( Bockaert, J; Gozlan, H; Homburger, V; Lucas, M; Michelot, R, 1980)
"Treatment of murine neuroblastoma N18 cells with N-ethylmaleimide under conditions that favor diminution of membrane potential leads to a 65% increase in the rate of veratridine-stimulated, tetrodotoxin-sensitive Na+ uptake and to a 50% decrease in the concentration of veratridine required for half-maximal stimulation."3.66Effects of N-ethylmaleimide treatment on the action potential Na+-ionophore of cultured neuroblastoma cells. ( Blumenthal, K; Panini, A, 1980)
"1) system that shows no measurable cyclizing activity but retains both an active glucagon receptor and a receptor-sensitive regulatory component N as assessed by reconstitution into cyclase-negative (cyc-) membranes from S49 murine lymphoma."3.66Hormone receptor modulates the regulatory component of adenylyl cyclase by reducing its requirement for Mg2+ and enhancing its extent of activation by guanine nucleotides. ( Birnbaumer, L; Iyengar, R, 1982)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199024 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vauquelin, G1
Maguire, ME1
Biaglow, JE1
Varnes, ME1
Jacobson, B1
Suit, HD1
Gozlan, H1
Homburger, V1
Lucas, M1
Bockaert, J1
Michelot, R1
Panini, A1
Blumenthal, K1
Iyengar, R1
Birnbaumer, L1
Blume, AJ1
Mullikin-Kilpatrick, D1
Larsen, NE1
Awad, JA1
Johnson, RA1
Jakobs, KH1
Schultz, G1
Wiestler, O1
von Deimling, A1
Kobori, O1
Kleihues, P1
Mosbaugh, DW1
Kunkel, TA1
Stalker, DM1
Tcheng, JE1
Meyer, RR1
Casellas, P1
Jeanteur, P1
Olson, MO1
Guetzow, K1
Ross, EM1
Howlett, AC1
Gilman, AG1
Hachmann, HJ1
Lezius, AG1
Weber, S1
Dölz, R1
Timpl, R1
Fessler, JH1
Engel, J1
Apffel, CA1
Walker, JE1
Nathanson, IT1
Pogell, BM1
Tanaka, A1
Siddons, RC1
Buccino, RJ1
Roth, JS1
Grunicke, H1
Bock, KW1
Becher, H1
Gäng, V1
Schnierda, J1
Puschendorf, B1
Tanabe, K1
Takahashi, T1
Watanabe, H1
Orth, DN1
Toft, DO1
Matsukage, A1
Bohn, EW1
Wilson, SH1
Prager, MD1
Searle, CE1
Klímek, M1

Reviews

1 review available for ethylmaleimide and Experimental Neoplasms

ArticleYear
Involvement of sulfhydryl groups in the functional integrity of the opiate receptors of neuroblastoma x glioma hybrid NG108-15.
    Advances in biochemical psychopharmacology, 1983, Volume: 36

    Topics: Animals; Enkephalins; Ethylmaleimide; Glioma; Hybrid Cells; Kinetics; Mice; Neoplasms, Experimental;

1983

Other Studies

23 other studies available for ethylmaleimide and Experimental Neoplasms

ArticleYear
Inactivation of beta-adrenergic receptors by N-ethylmaleimide in S49 lymphoma cells. Agonist induction of functional receptor heterogeneity.
    Molecular pharmacology, 1980, Volume: 18, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Cell Membrane; Cells, Cultured; Erythrocyte Membrane; Ethylmaleim

1980
Control of oxygen utilization in vitro and in vivo: implications for radiotherapy of tumors.
    Advances in experimental medicine and biology, 1984, Volume: 180

    Topics: Animals; Cricetinae; Ethylmaleimide; Glutamates; Glutamic Acid; Humans; In Vitro Techniques; Mice; N

1984
Irreversible inactivation of beta-adrenergic receptors of C6 glioma cells. Synthesis and study of a thiol derivative of propranolol.
    Biochimie, 1980, Volume: 62, Issue:7

    Topics: Adenylyl Cyclases; Animals; Cell Line; Dithiothreitol; Ethylmaleimide; Glioma; Isoproterenol; Kineti

1980
Effects of N-ethylmaleimide treatment on the action potential Na+-ionophore of cultured neuroblastoma cells.
    Journal of neurochemistry, 1980, Volume: 35, Issue:3

    Topics: Action Potentials; Animals; Cells, Cultured; Ethylmaleimide; Ion Channels; Ionophores; Mice; Neoplas

1980
Hormone receptor modulates the regulatory component of adenylyl cyclase by reducing its requirement for Mg2+ and enhancing its extent of activation by guanine nucleotides.
    Proceedings of the National Academy of Sciences of the United States of America, 1982, Volume: 79, Issue:17

    Topics: Adenylyl Cyclases; Animals; Cell Line; Cell Membrane; Ethylmaleimide; Glucagon; Guanosine 5'-O-(3-Th

1982
Interactions of forskolin and adenylate cyclase. Effects on substrate kinetics and protection against inactivation by heat and N-ethylmaleimide.
    The Journal of biological chemistry, 1983, Mar-10, Volume: 258, Issue:5

    Topics: Adenylyl Cyclases; Animals; Blood Platelets; Brain; Cell Membrane; Colforsin; Diterpenes; Erythrocyt

1983
Location of N-methyl-N'-nitro-N-nitrosoguanidine-induced gastrointestinal tumors correlates with thiol distribution.
    Carcinogenesis, 1983, Volume: 4, Issue:7

    Topics: Animals; Carbon Radioisotopes; Duodenal Neoplasms; Esophageal Neoplasms; Ethylmaleimide; Female; Gas

1983
Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents.
    Nucleic acids research, 1976, Volume: 3, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; Dithiothreitol; DNA; Escherichia coli; Ethylmaleimide; Guinea Pi

1976
Protein methylation in animal cells. I. Purification and properties of S-adenosyl-L-methionine:protein (arginine) N-methyltransferase from Krebs II ascites cells.
    Biochimica et biophysica acta, 1978, Jun-22, Volume: 519, Issue:1

    Topics: Animals; Chromatography; Ethylmaleimide; Hydrogen-Ion Concentration; Kinetics; Mice; Molecular Weigh

1978
Phosphoprotein phosphatase activity of Novikoff hepatoma nucleoli.
    Biochemical and biophysical research communications, 1976, Jun-07, Volume: 70, Issue:3

    Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cell Nucleolus; Cobalt; Dithiothreitol; Edetic Acid; Et

1976
Identification and partial characterization of some components of hormone-stimulated adenylate cyclase.
    Progress in clinical and biological research, 1979, Volume: 31

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cells, Cultured; Ethylmaleimide; Guanylyl Imidodiphosphat

1979
High-molecular-weight DNA polymerases from mouse myeloma. Purification and properties of three enzymes.
    European journal of biochemistry, 1975, Jan-02, Volume: 50, Issue:2

    Topics: Animals; Cardiolipins; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatogra

1975
Reductive cleavage and reformation of the interchain and intrachain disulfide bonds in the globular hexameric domain NC1 involved in network assembly of basement membrane collagen (type IV).
    European journal of biochemistry, 1988, Aug-01, Volume: 175, Issue:2

    Topics: Animals; Basement Membrane; Collagen; Disulfides; Ethylmaleimide; Female; Humans; Kidney; Kinetics;

1988
Tumor growth and disulfide reduction: possible dependence on protein-disulfide reductase.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:2

    Topics: Animals; Antigens, Neoplasm; Arsenic; Ascitic Fluid; Cell Survival; Cell-Free System; Cysteine; Disu

1973
Natural activators for liver fructose 1,6-diphosphatase and the reversal of adenosine 5'-monophosphate inhibition by muscle phosphofructokinase.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Aldehyde-Lyases; Animals; Benzoates; Carcinoma, Hepatoc

1968
Partial purification and properties of ATP:GMP phosphransferase from rat liver.
    Archives of biochemistry and biophysics, 1969, Volume: 132, Issue:1

    Topics: Adenosine Triphosphate; Amides; Animals; Benzoates; Carbon Isotopes; Carcinoma, Hepatocellular; Cesi

1969
Effect of alkylating antitumor agents on the binding of DNA to protein.
    Cancer research, 1973, Volume: 33, Issue:5

    Topics: Age Factors; Alkanesulfonates; Alkylating Agents; Animals; Animals, Newborn; Antineoplastic Agents;

1973
Conversion of DNA polymerase extracted from rat ascites hepatoma cells.
    Biochemical and biophysical research communications, 1973, Jul-02, Volume: 53, Issue:1

    Topics: Animals; Ascitic Fluid; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Chlo

1973
Glucocorticoid receptors in mouse pituitary tumor cells. II. Nuclear binding.
    Biochemistry, 1974, Jan-15, Volume: 13, Issue:2

    Topics: Animals; Binding Sites; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Charcoal

1974
Multiple forms of DNA polymerase in mouse myeloma.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:2

    Topics: Animals; Cell Membrane; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulo

1974
Vaccination and immunotherapy with chemically modified cancer cells.
    Bibliotheca haematologica, 1973, Volume: 39

    Topics: Animals; Antibodies, Neoplasm; Dinitrophenols; Ethylmaleimide; Fluorescent Antibody Technique; Immun

1973
Tumor initiatory activity of some chloromononitrobenzenes and other compounds.
    Cancer research, 1966, Volume: 26, Issue:1

    Topics: Acetone; Animals; Croton Oil; Ethylmaleimide; Female; Male; Mice; Neoplasms, Experimental; Nitrobenz

1966
Radiosensitization of human tumour cells in vitro by N-ethylmaleinimide under hypoxic conditions.
    Neoplasma, 1966, Volume: 13, Issue:1

    Topics: Culture Techniques; Ethylmaleimide; HeLa Cells; Hypoxia; Neoplasms, Experimental; Radiation Effects;

1966