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ethylmaleimide and Cell Transformation, Neoplastic

ethylmaleimide has been researched along with Cell Transformation, Neoplastic in 9 studies

Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"The diamide effect was reversible with excess of DTT, whereas DTT could not restore the DNA binding of AML1 treated with N-ethylmaleimide."1.29A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA binding ability and the transforming activity on fibroblasts. ( Hirai, H; Hirano, N; Kurokawa, M; Mitani, K; Ogawa, S; Tanaka, K; Tanaka, T; Yazaki, Y, 1996)
"Herbimycin A is an antiobiotic which reverses transformation caused by src family oncogenes."1.28Effects of herbimycin A and various SH-reagents on p60v-src kinase activity in vitro. ( Fukazawa, H; Mizuno, S; Uehara, Y, 1990)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reilly, TM1
Blecher, M1
Mattern, MR1
Li, PM1
Fukazawa, H2
Yamamoto, C1
Mizuno, S2
Tanaka, K2
Hori, M1
Yaginuma, S1
Saito, T1
Uehara, Y2
Kurokawa, M1
Tanaka, T1
Hirano, N1
Ogawa, S1
Mitani, K1
Yazaki, Y1
Hirai, H1
Quinlan, DC1
Hochstadt, J1
Crawford, LV1
O'Farrell, PZ1
Yu, KT1
Werth, DK1
Pastan, IH1
Czech, MP1
Hung, PP1

Other Studies

9 other studies available for ethylmaleimide and Cell Transformation, Neoplastic

ArticleYear
Restoration of glucagon responsiveness in spontaneously transformed rat hepatocytes (RL-PR-C) by fusion with normal progenitor cells and rat liver plasma membranes.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Fusion; Cell Membrane; Cell Transformation, Neoplastic; C

1981
Differences between diploid and transformed human cells in the incorporation of 5-bromodeoxyuridine into DNA.
    Experimental cell research, 1980, Volume: 128, Issue:1

    Topics: Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Diploidy; DNA; DNA-Directed DNA Polym

1980
Method of identifying inhibitors of oncogenic transformation: selective inhibition of cell growth in serum-free medium.
    Oncogene, 1993, Volume: 8, Issue:7

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Benzoquinones; Cell Division; Cell Transformation, Neopla

1993
A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA binding ability and the transforming activity on fibroblasts.
    The Journal of biological chemistry, 1996, Jul-12, Volume: 271, Issue:28

    Topics: 3T3 Cells; Animals; Cell Line; Cell Transformation, Neoplastic; Conserved Sequence; Core Binding Fac

1996
Group translocation of the ribose moiety of inosine by vesicles of plasma membrane from T(3 cells transformed by Simian virus 40.
    The Journal of biological chemistry, 1976, Jan-25, Volume: 251, Issue:2

    Topics: Binding, Competitive; Biological Transport, Active; Cell Line; Cell Membrane; Cell Transformation, N

1976
Effect of alkylation on the physical properties of simian virus 40 T-antigen species.
    Journal of virology, 1979, Volume: 29, Issue:2

    Topics: Alkylation; Antigens, Neoplasm; Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Ethylma

1979
Effects of herbimycin A and various SH-reagents on p60v-src kinase activity in vitro.
    Biochemical and biophysical research communications, 1990, Nov-30, Volume: 173, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Avian Sarcoma Viruses; Benzoquinones; Cell Line; Cell Transfor

1990
src kinase catalyzes the phosphorylation and activation of the insulin receptor kinase.
    The Journal of biological chemistry, 1985, May-10, Volume: 260, Issue:9

    Topics: Amino Acids; Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chromatography, High P

1985
Rescue of chemically inactivated Rous sarcoma virus transforming activity by avian leukosis virus.
    Virology, 1973, Volume: 53, Issue:2

    Topics: Animals; Antibodies, Viral; Avian Leukosis Virus; Avian Sarcoma Viruses; Cell Transformation, Neopla

1973