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ethylmaleimide and Carcinoma, Hepatocellular

ethylmaleimide has been researched along with Carcinoma, Hepatocellular in 16 studies

Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.

Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.

Research Excerpts

ExcerptRelevanceReference
"Ebselen analogues were also more effective antiviral agents, and they were less toxic to hepatocytes than ebselen."5.40Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication. ( Frick, DN; Hanson, AM; Isailovic, D; Kolli, R; Marvin, RK; Mukherjee, S; Ndjomou, J; Schoenen, FJ; Schroeder, CE; Simpson, DS; Sweeney, NL; Weiner, WS, 2014)
"Ebselen analogues were also more effective antiviral agents, and they were less toxic to hepatocytes than ebselen."1.40Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication. ( Frick, DN; Hanson, AM; Isailovic, D; Kolli, R; Marvin, RK; Mukherjee, S; Ndjomou, J; Schoenen, FJ; Schroeder, CE; Simpson, DS; Sweeney, NL; Weiner, WS, 2014)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's1 (6.25)18.2507
2000's3 (18.75)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mukherjee, S1
Weiner, WS1
Schroeder, CE1
Simpson, DS1
Hanson, AM1
Sweeney, NL1
Marvin, RK1
Ndjomou, J1
Kolli, R1
Isailovic, D1
Schoenen, FJ1
Frick, DN1
Lee, JW1
Kim, JE1
Park, EJ1
Kim, JH1
Lee, CH1
Lee, SR1
Kwon, J1
Vadgama, JV1
Christensen, HN1
Kim, JA2
Kang, YS1
Lee, YS2
Tanabe, K2
Takahashi, T2
Mosbaugh, DW1
Kunkel, TA1
Stalker, DM1
Tcheng, JE1
Meyer, RR1
Olson, MO1
Guetzow, K1
Bommer, UA1
Henske, A1
Bielka, H1
Pitt, A1
Schwartz, AL1
Chiles, TC1
Kilberg, MS1
Pogell, BM1
Tanaka, A1
Siddons, RC1
Buccino, RJ1
Roth, JS1
Grinnell, F1
Milam, M1
Srere, PA1
Gronow, M1
Thackrah, TM1

Other Studies

16 other studies available for ethylmaleimide and Carcinoma, Hepatocellular

ArticleYear
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication.
    ACS chemical biology, 2014, Oct-17, Volume: 9, Issue:10

    Topics: Antioxidants; Antiviral Agents; Azoles; Carcinoma, Hepatocellular; Cell Proliferation; Electrophoret

2014
Two conserved cysteine residues are critical for the enzymic function of the human platelet-derived growth factor receptor-beta: evidence for different roles of Cys-822 and Cys-940 in the kinase activity.
    The Biochemical journal, 2004, Sep-01, Volume: 382, Issue:Pt 2

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Carcinoma, Hepatocellular; Cell Line; Cell Lin

2004
Comparison of system N in fetal hepatocytes and in related cell lines.
    The Journal of biological chemistry, 1983, May-25, Volume: 258, Issue:10

    Topics: Aging; Amino Acids; Aminoisobutyric Acids; Animals; Asparagine; Biological Transport; Carcinoma, Ehr

1983
Involvement of K(+)-Cl(-)-cotransport in the apoptosis induced by N-ethylmaleimide in HepG2 human hepatoblastoma cells.
    European journal of pharmacology, 2001, Apr-20, Volume: 418, Issue:1-2

    Topics: Apoptosis; Carcinoma, Hepatocellular; Carrier Proteins; Chlorides; Ethylmaleimide; Flow Cytometry; G

2001
Role of reactive oxygen species generated by NADPH oxidase in the mechanism of activation of K(+)-Cl(-)-cotransport by N-ethylmaleimide in HepG2 human hepatoma cells.
    Free radical research, 2001, Volume: 35, Issue:1

    Topics: Carcinoma, Hepatocellular; Chlorides; Enzyme Inhibitors; Ethylmaleimide; Genistein; Humans; K Cl- Co

2001
Studies on the molecular species of DNA polymerase extracted from rat ascites hepatoma cells.
    Journal of biochemistry, 1976, Volume: 79, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; DNA Nucleotidyltransferases; Eth

1976
Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents.
    Nucleic acids research, 1976, Volume: 3, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; Dithiothreitol; DNA; Escherichia coli; Ethylmaleimide; Guinea Pi

1976
Phosphoprotein phosphatase activity of Novikoff hepatoma nucleoli.
    Biochemical and biophysical research communications, 1976, Jun-07, Volume: 70, Issue:3

    Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cell Nucleolus; Cobalt; Dithiothreitol; Edetic Acid; Et

1976
Preparation and properties of a Met-tRNAf binding factor from rat liver and rat hepatoma.
    Acta biologica et medica Germanica, 1978, Volume: 37, Issue:9

    Topics: Animals; Carcinoma, Hepatocellular; Ethylmaleimide; Guanosine Diphosphate; Guanosine Triphosphate; H

1978
Reconstitution of human hepatoma endosome-endosome fusion in vitro: potential roles for an endoprotease and a phosphoprotein phosphatase.
    European journal of cell biology, 1991, Volume: 55, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Fusion; Dipeptides; Endopeptidases; Enzyme-Linked Immunosor

1991
System A transport activity in normal rat hepatocytes and transformed liver cells: substrate protection from inactivation by sulfhydryl-modifying reagents.
    Journal of cellular physiology, 1986, Volume: 129, Issue:3

    Topics: 4-Chloromercuribenzenesulfonate; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport;

1986
Natural activators for liver fructose 1,6-diphosphatase and the reversal of adenosine 5'-monophosphate inhibition by muscle phosphofructokinase.
    The Journal of biological chemistry, 1968, Apr-10, Volume: 243, Issue:7

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Aldehyde-Lyases; Animals; Benzoates; Carcinoma, Hepatoc

1968
Partial purification and properties of ATP:GMP phosphransferase from rat liver.
    Archives of biochemistry and biophysics, 1969, Volume: 132, Issue:1

    Topics: Adenosine Triphosphate; Amides; Animals; Benzoates; Carbon Isotopes; Carcinoma, Hepatocellular; Cesi

1969
Studies on cell adhesion. II. Adhesion of cells to surfaces of diverse chemical composition and inhibition of adhesion by sulfhydryl binding reagents.
    Archives of biochemistry and biophysics, 1972, Volume: 153, Issue:1

    Topics: Agar; Alloys; Aluminum; Animals; Arsenic; Carcinoma, Hepatocellular; Cell Adhesion; Cell Division; C

1972
Conversion of DNA polymerase extracted from rat ascites hepatoma cells.
    Biochemical and biophysical research communications, 1973, Jul-02, Volume: 53, Issue:1

    Topics: Animals; Ascitic Fluid; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Chlo

1973
Nuclear protein changes during the nitrosamine-induced carcinogenesis of rat liver.
    Chemico-biological interactions, 1974, Volume: 9, Issue:3

    Topics: Animals; Binding Sites; Carbon Radioisotopes; Carcinogens; Carcinoma, Hepatocellular; Cell Nucleus;

1974