ethylmaleimide has been researched along with Anemia, Sickle Cell in 12 studies
Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies.
Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In certain pathologic states, such as sickle cell anemia, phospholipid asymmetry is altered." | 1.29 | Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V. ( Discher, D; Ernst, JD; Hua, M; Kuypers, FA; Lewis, RA; Lubin, BH; Schott, MA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muzyamba, MC | 1 |
| Campbell, EH | 1 |
| Gibson, JS | 1 |
| Knee, KM | 1 |
| Roden, CK | 1 |
| Flory, MR | 1 |
| Mukerji, I | 1 |
| Sato, T | 1 |
| Ohnishi, ST | 1 |
| Buchanan, GR | 1 |
| Holtkamp, CA | 1 |
| Kuypers, FA | 1 |
| Lewis, RA | 1 |
| Hua, M | 1 |
| Schott, MA | 1 |
| Discher, D | 1 |
| Ernst, JD | 1 |
| Lubin, BH | 1 |
| Godart, H | 1 |
| Dormandy, A | 1 |
| Ellory, JC | 1 |
| al-Rohil Gharaibeh, NS | 1 |
| al-Sheyyab, M | 1 |
| Vitoux, D | 2 |
| Beuzard, Y | 2 |
| Brugnara, C | 1 |
| Moore, RB | 1 |
| Hulgan, TM | 1 |
| Green, JW | 1 |
| Jenkins, LD | 1 |
| Olivieri, O | 1 |
| Garay, RP | 1 |
| Cragoe, EJ | 1 |
| Galacteros, F | 2 |
| al-Rohil, N | 1 |
| Jennings, ML | 1 |
| Leclerc, L | 1 |
| Girard, F | 1 |
| Poyart, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sickle Cell Disease (SCD) Biochip': Towards a Simple and Reliable Way to Monitor Sickle Cell Disease[NCT02824471] | 100 participants (Anticipated) | Observational | 2014-10-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for ethylmaleimide and Anemia, Sickle Cell
| Article | Year |
|---|---|
Effect of intracellular magnesium and oxygen tension on K+-Cl- cotransport in normal and sickle human red cells.
Topics: Anemia, Sickle Cell; Antisickling Agents; Dimethyl Adipimidate; Enzyme Inhibitors; Erythrocytes; Ery | 2006 |
The role of beta93 Cys in the inhibition of Hb S fiber formation.
Topics: Anemia, Sickle Cell; Cysteine; Ethylmaleimide; Hemoglobin, Sickle; Humans; Methemoglobin; Nitric Oxi | 2007 |
Effects of sulfhydryl reagents on the anti-sickling activity of some membrane-interacting compounds.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Chlorpromazine; Erythrocytes; Ethylmaleimide; Human | 1983 |
Platelet aggregation, malondialdehyde generation and production time in children with sickle cell anaemia.
Topics: Adenosine Diphosphate; Adolescent; Anemia, Sickle Cell; Blood Platelets; Child; Child, Preschool; Co | 1981 |
Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V.
Topics: Anemia, Sickle Cell; Annexin A5; Calcimycin; Calcium; Cell Separation; Erythrocyte Membrane; Erythro | 1996 |
Do HbSS erythrocytes lose KCl in physiological conditions?
Topics: Adolescent; Adult; Anemia, Sickle Cell; Bicarbonates; Erythrocytes; Ethylmaleimide; Female; Humans; | 1997 |
Inhibition of K+ transport in human sickle cell erythrocytes by okadaic acid and sodium fluoride.
Topics: Anemia, Sickle Cell; Dose-Response Relationship, Drug; Erythrocytes, Abnormal; Ethylmaleimide; Hemog | 1997 |
The effect of hemoglobin A and S on the volume- and pH-dependence of K-Cl cotransport in human erythrocyte ghosts.
Topics: Anemia, Sickle Cell; Carrier Proteins; Cell Size; Centrifugation, Density Gradient; Chlorides; Eryth | 1999 |
Increased susceptibility of the sickle cell membrane Ca2+ + Mg(2+)-ATPase to t-butylhydroperoxide: protective effects of ascorbate and desferal.
Topics: Anemia, Sickle Cell; Ascorbic Acid; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Calmodulin; | 1992 |
Inhibition of K+ efflux and dehydration of sickle cells by [(dihydroindenyl)oxy]alkanoic acid: an inhibitor of the K+ Cl- cotransport system.
Topics: Anemia, Sickle Cell; Carboxylic Acids; Carrier Proteins; Erythrocytes; Ethylmaleimide; Humans; In Vi | 1989 |
Volume-dependent K+ transport in rabbit red blood cells comparison with oxygenated human SS cells.
Topics: Anemia, Sickle Cell; Animals; Anions; Biological Transport; Chlorides; Disease Models, Animal; Eryth | 1989 |
The calmodulin-stimulated (Ca2+ + Mg2+)-ATPase in hemoglobin S erythrocyte membranes: effects of sickling and oxidative agents.
Topics: Anemia, Sickle Cell; Ca(2+) Mg(2+)-ATPase; Calcium-Transporting ATPases; Calmodulin; Diamide; Erythr | 1987 |