ethylisopropylamiloride has been researched along with Urinary Bladder Neoplasms in 2 studies
ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.
Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Unexpectedly, the uptake of BCG by bladder cancer cells occurs by macropinocytosis rather than phagocytosis." | 1.39 | Oncogenic activation of Pak1-dependent pathway of macropinocytosis determines BCG entry into bladder cancer cells. ( Glickman, MS; Iyer, G; Redelman-Sidi, G; Solit, DB, 2013) |
| " Weak acids that are normal cellular metabolites are not toxic in vivo, but weak acids carrying cytotoxic groups offer the potential for selective uptake and toxicity under the conditions of low pHe that exist in many solid tumours." | 1.29 | Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment. ( Dobrowsky, E; Karuri, AR; Tannock, IF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Redelman-Sidi, G | 1 |
| Iyer, G | 1 |
| Solit, DB | 1 |
| Glickman, MS | 1 |
| Karuri, AR | 1 |
| Dobrowsky, E | 1 |
| Tannock, IF | 1 |
2 other studies available for ethylisopropylamiloride and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
Oncogenic activation of Pak1-dependent pathway of macropinocytosis determines BCG entry into bladder cancer cells.
Topics: Amiloride; BCG Vaccine; cdc42 GTP-Binding Protein; Cell Line, Tumor; Clathrin; Cytochalasin D; Dynam | 2013 |
Selective cellular acidification and toxicity of weak organic acids in an acidic microenvironment.
Topics: Amiloride; Animals; Butyrates; Butyric Acid; Carboxylic Acids; Cell Hypoxia; Cell Survival; Female; | 1993 |