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ethylisopropylamiloride and Reperfusion Injury

ethylisopropylamiloride has been researched along with Reperfusion Injury in 6 studies

ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"untreated), cariporide (p < 0."5.32Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide. ( ten Hove, M; van Echteld, CJ; van Emous, JG, 2003)
"The effect of the selective Na(+)/H(+) antiporter inhibitor 5-(N-ethyl-N-isopropyl)-amiloride (EIPA) on cerebral ischemia/reperfusion injury was evaluated in the Mongolian gerbil."3.705-(N-Ethyl-N-isopropyl)-amiloride, an Na(+)-H(+) exchange inhibitor, protects gerbil hippocampal neurons from ischemic injury. ( Estevez, AY; Guyot, LL; O'Regan, MH; Phillis, JW, 1999)
"untreated), cariporide (p < 0."1.32Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide. ( ten Hove, M; van Echteld, CJ; van Emous, JG, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ten Hove, M1
van Emous, JG1
van Echteld, CJ1
Huck, V1
Niemeyer, A1
Goerge, T1
Schnaeker, EM1
Ossig, R1
Rogge, P1
Schneider, MF1
Oberleithner, H1
Schneider, SW1
Yamashita, J1
Ohkita, M1
Takaoka, M1
Kaneshiro, Y1
Matsuo, T1
Kaneko, K1
Matsumura, Y1
Hotta, Y1
Fujita, M1
Nakagawa, J1
Ando, H1
Takeya, K1
Ishikawa, N1
Sakakibara, J1
Phillis, JW2
Estevez, AY1
Guyot, LL1
O'Regan, MH2
Ren, J1

Other Studies

6 other studies available for ethylisopropylamiloride and Reperfusion Injury

ArticleYear
Na+ overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+ exchange blockers EIPA, cariporide and eniporide.
    Molecular and cellular biochemistry, 2003, Volume: 250, Issue:1-2

    Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Guanidines; Hydrogen-Ion Concentration; Ischemi

2003
Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation.
    Journal of cellular physiology, 2007, Volume: 211, Issue:2

    Topics: Acidosis; Amiloride; Calcium; Cell Adhesion; Cells, Cultured; Chloride-Bicarbonate Antiporters; Cycl

2007
Role of Na+/H+ exchanger in the pathogenesis of ischemic acute renal failure in mice.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:3

    Topics: Acute Kidney Injury; Amiloride; Animals; Endothelin-1; Kidney; Kidney Tubular Necrosis, Acute; Kidne

2007
Contribution of cytosolic ionic and energetic milieu change to ischemia- and reperfusion-induced injury in guinea pig heart: fluorometry and nuclear magnetic resonance studies.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1

    Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Cytosol; Enzyme Inhibitors; Female; Fluorometry

1998
5-(N-Ethyl-N-isopropyl)-amiloride, an Na(+)-H(+) exchange inhibitor, protects gerbil hippocampal neurons from ischemic injury.
    Brain research, 1999, Aug-21, Volume: 839, Issue:1

    Topics: Amiloride; Animals; Brain Ischemia; Gerbillinae; Hippocampus; Male; Neurons; Neuroprotective Agents;

1999
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
    Brain research, 2000, Nov-24, Volume: 884, Issue:1--2

    Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Corte

2000