ethylisopropylamiloride has been researched along with Muscular Atrophy, Spinal in 2 studies
ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuo, CY | 1 |
| Lin, HH | 1 |
| Chang, YS | 1 |
| Yang, WK | 1 |
| Chang, JG | 1 |
| Burnett, BG | 1 |
| Sumner, CJ | 1 |
2 other studies available for ethylisopropylamiloride and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
5-(N-ethyl-N-isopropyl)-amiloride enhances SMN2 exon 7 inclusion and protein expression in spinal muscular atrophy cells.
Topics: Alternative Splicing; Amiloride; Cell Line; Cell Survival; Cyclic AMP Response Element-Binding Prote | 2008 |
Targeting splicing in spinal muscular atrophy.
Topics: Amiloride; Cyclic AMP Response Element-Binding Protein; Exons; Gene Expression Regulation; Genetic P | 2008 |