ethylisopropylamiloride has been researched along with Injury, Myocardial Reperfusion in 13 studies
ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We tested the effects of 1 mM amiloride, which is known to inhibit both Na+/H+ and Na+/Ca2+ exchange, and 3 microM 5-(N-ethyl-N-isopropyl) amiloride (EIPA), which is known to act as a specific inhibitor against Na+/H+ exchange, on the incidence of ventricular arrhythmias, isovolumic left ventricular function and creatine kinase (CK) release during reperfusion after 15 or 30 min of global ischemia in the isolated and perfused guinea pig heart." | 7.68 | Effects of amiloride and an analogue on ventricular arrhythmias, contracture and cellular injury during reperfusion in isolated and perfused guinea pig heart. ( Cragoe, EJ; Fukunaka, M; Imamura, H; Kagawa, K; Kato, Y; Ko, T; Otani, H; Sakurai, Y; Tanaka, K, 1991) |
| " We tested the effects of 1 mM amiloride, which is known to inhibit both Na+/H+ and Na+/Ca2+ exchange, and 3 microM 5-(N-ethyl-N-isopropyl) amiloride (EIPA), which is known to act as a specific inhibitor against Na+/H+ exchange, on the incidence of ventricular arrhythmias, isovolumic left ventricular function and creatine kinase (CK) release during reperfusion after 15 or 30 min of global ischemia in the isolated and perfused guinea pig heart." | 3.68 | Effects of amiloride and an analogue on ventricular arrhythmias, contracture and cellular injury during reperfusion in isolated and perfused guinea pig heart. ( Cragoe, EJ; Fukunaka, M; Imamura, H; Kagawa, K; Kato, Y; Ko, T; Otani, H; Sakurai, Y; Tanaka, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersen, AD | 1 |
| Bentzen, BH | 1 |
| Salling, H | 1 |
| Klingberg, H | 1 |
| Kanneworff, M | 1 |
| Grunnet, M | 1 |
| Pedersen, SF | 1 |
| Yamamoto, S | 1 |
| Matsumoto, N | 1 |
| Kanazawa, M | 1 |
| Fujita, M | 1 |
| Takaoka, M | 1 |
| Gariepy, CE | 1 |
| Yanagisawa, M | 1 |
| Matsumura, Y | 1 |
| Yasutake, M | 1 |
| Ibuki, C | 1 |
| Hearse, DJ | 1 |
| Avkiran, M | 1 |
| Liu, H | 1 |
| Cala, PM | 1 |
| Anderson, SE | 1 |
| Van Emous, JG | 2 |
| Schreur, JH | 1 |
| Ruigrok, TJ | 1 |
| Van Echteld, CJ | 2 |
| Munch-Ellingsen, J | 1 |
| Løkebø, JE | 1 |
| Bugge, E | 1 |
| Ytrehus, K | 1 |
| Ramasamy, R | 1 |
| Schaefer, S | 1 |
| Toda, H | 1 |
| Noguchi, T | 1 |
| Miyagishi, A | 1 |
| Ito, N | 1 |
| Umekawa, K | 1 |
| Sato, Y | 1 |
| Kitano, M | 1 |
| Ohashi, N | 2 |
| ten Hove, M | 1 |
| Sharma, A | 1 |
| Singh, M | 1 |
| Hotta, Y | 1 |
| Nakagawa, J | 1 |
| Ishikawa, N | 1 |
| Wakida, Y | 1 |
| Ando, H | 1 |
| Takeya, K | 1 |
| Matsui, K | 1 |
| Otani, H | 1 |
| Kato, Y | 1 |
| Ko, T | 1 |
| Sakurai, Y | 1 |
| Kagawa, K | 1 |
| Tanaka, K | 1 |
| Fukunaka, M | 1 |
| Imamura, H | 1 |
| Cragoe, EJ | 1 |
| Vasilets, LA | 1 |
| Mokh, VP | 1 |
| Khodorov, BI | 1 |
13 other studies available for ethylisopropylamiloride and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na(+)/H(+) exchanger NHE1.
Topics: Acids; Amiloride; Animals; Apoptosis; Cells, Cultured; Hydrogen-Ion Concentration; Ischemic Postcond | 2011 |
Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts.
Topics: Amiloride; Animals; Animals, Genetically Modified; Atrasentan; Endothelin A Receptor Antagonists; En | 2005 |
Na+/H+ exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardi | 1994 |
Ethylisopropylamiloride diminishes changes in intracellular Na, Ca and pH in ischemic newborn myocardium.
Topics: Adenosine Triphosphate; Age Factors; Amiloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; C | 1997 |
Both Na+-K+ ATPase and Na +-H+ exchanger are immediately active upon post-ischemic reperfusion in isolated rat hearts.
Topics: Amiloride; Animals; Enzyme Inhibitors; Heart; In Vitro Techniques; Kinetics; Magnetic Resonance Spec | 1998 |
Equal reduction in infarct size by ethylisopropyl-amiloride pretreatment and ischemic preconditioning in the in situ rabbit heart.
Topics: Amiloride; Animals; Female; Ion Transport; Ischemic Preconditioning, Myocardial; Male; Myocardial In | 1998 |
Inhibition of Na+-H+ exchanger protects diabetic and non-diabetic hearts from ischemic injury: insight into altered susceptibility of diabetic hearts to ischemic injury.
Topics: Acidosis; Adenosine Triphosphate; Amiloride; Animals; Calcium; Diabetes Mellitus, Type 1; Hydrogen-I | 1999 |
Cardioprotection of SM-15681, an Na+/H+ exchange inhibitor in ischemic and hypoxic isolated perfused rat hearts.
Topics: Amides; Amiloride; Animals; Anti-Arrhythmia Agents; Hydrogen; Indoles; Ion Transport; Myocardial Isc | 1999 |
Na+-overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+-exchange blockers EIPA, HOE642 and EMD96785.
Topics: Amiloride; Animals; Guanidines; In Vitro Techniques; Magnetic Resonance Spectroscopy; Myocardial Isc | 2000 |
Effect of ethylisopropyl amiloride, a Na+ - H+ exchange inhibitor, on cardioprotective effect of ischaemic and angiotensin preconditioning.
Topics: Amiloride; Angiotensin II; Animals; Cardiovascular Agents; Creatine Kinase; Female; Hemodynamics; Is | 2000 |
Protective effect of SM-20550, a selective Na+ - H+ exchange inhibitor, on ischemia-reperfusion-injured hearts.
Topics: Adenosine Triphosphate; Amidines; Amiloride; Animals; Calcium; Female; Guinea Pigs; Hydrogen-Ion Con | 2001 |
Effects of amiloride and an analogue on ventricular arrhythmias, contracture and cellular injury during reperfusion in isolated and perfused guinea pig heart.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Calcium; Contractu | 1991 |
[Prevention of reperfusion-induced arrhythmia by Na+/H+ exchange block].
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Hydrogen-Ion Concentration; In Vitr | 1989 |