ethylisopropylamiloride has been researched along with Heart Disease, Ischemic in 21 studies
ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of angiotensin II (10(-12)-10(-6) M) on H+ fluxes after intracellular acid loading and during reperfusion after myocardial ischemia have been investigated in the isovolumic, Langendorff-perfused ferret heart." | 3.69 | Angiotensin II stimulates sodium-dependent proton extrusion in perfused ferret heart. ( Bethell, HW; Grace, AA; Metcalfe, JC; Vandenberg, JI; Weissberg, PL, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (66.67) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersen, AD | 1 |
| Bentzen, BH | 1 |
| Salling, H | 1 |
| Klingberg, H | 1 |
| Kanneworff, M | 1 |
| Grunnet, M | 1 |
| Pedersen, SF | 1 |
| Yamamoto, S | 2 |
| Matsumoto, N | 1 |
| Kanazawa, M | 1 |
| Fujita, M | 1 |
| Takaoka, M | 1 |
| Gariepy, CE | 1 |
| Yanagisawa, M | 1 |
| Matsumura, Y | 1 |
| Bugge, E | 1 |
| Ytrehus, K | 1 |
| Navon, G | 1 |
| Werrmann, JG | 1 |
| Maron, R | 1 |
| Cohen, SM | 1 |
| Yasutake, M | 1 |
| Ibuki, C | 1 |
| Hearse, DJ | 1 |
| Avkiran, M | 1 |
| Pike, MM | 1 |
| Luo, CS | 1 |
| Clark, MD | 1 |
| Kirk, KA | 1 |
| Kitakaze, M | 1 |
| Madden, MC | 1 |
| Cragoe, EJ | 1 |
| Pohost, GM | 1 |
| Scholz, W | 2 |
| Albus, U | 2 |
| Lang, HJ | 2 |
| Linz, W | 2 |
| Martorana, PA | 1 |
| Englert, HC | 1 |
| Schölkens, BA | 2 |
| Grace, AA | 1 |
| Metcalfe, JC | 1 |
| Weissberg, PL | 1 |
| Bethell, HW | 1 |
| Vandenberg, JI | 1 |
| Khandoudi, N | 1 |
| Laville, MP | 1 |
| Bril, A | 1 |
| Schaefer, S | 1 |
| Ramasamy, R | 1 |
| Liu, H | 1 |
| Cala, PM | 1 |
| Anderson, SE | 1 |
| Rehring, TF | 1 |
| Shapiro, JI | 1 |
| Cain, BS | 1 |
| Meldrum, DR | 1 |
| Cleveland, JC | 1 |
| Harken, AH | 1 |
| Banerjee, A | 1 |
| Gerber, SH | 1 |
| Heyer, C | 1 |
| Krüger, C | 1 |
| Hagl, S | 1 |
| Kübler, W | 1 |
| Haass, M | 1 |
| Smith, NC | 1 |
| Levi, R | 1 |
| Toda, H | 1 |
| Noguchi, T | 1 |
| Miyagishi, A | 1 |
| Ito, N | 1 |
| Umekawa, K | 1 |
| Sato, Y | 1 |
| Kitano, M | 2 |
| Ohashi, N | 3 |
| Schäfer, C | 1 |
| Ladilov, YV | 1 |
| Schäfer, M | 1 |
| Piper, HM | 1 |
| Matsui, K | 2 |
| Sasabe, M | 1 |
| ten Hove, M | 1 |
| van Emous, JG | 1 |
| van Echteld, CJ | 1 |
| Hotta, Y | 1 |
| Nakagawa, J | 1 |
| Ishikawa, N | 1 |
| Wakida, Y | 1 |
| Ando, H | 1 |
| Takeya, K | 1 |
| Iwai, T | 1 |
| Tanonaka, K | 1 |
| Inoue, R | 1 |
| Kasahara, S | 1 |
| Kamo, N | 1 |
| Takeo, S | 1 |
| Martorana, P | 1 |
21 other studies available for ethylisopropylamiloride and Heart Disease, Ischemic
| Article | Year |
|---|---|
The cardioprotective effect of brief acidic reperfusion after ischemia in perfused rat hearts is not mimicked by inhibition of the Na(+)/H(+) exchanger NHE1.
Topics: Acids; Amiloride; Animals; Apoptosis; Cells, Cultured; Hydrogen-Ion Concentration; Ischemic Postcond | 2011 |
Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts.
Topics: Amiloride; Animals; Animals, Genetically Modified; Atrasentan; Endothelin A Receptor Antagonists; En | 2005 |
Inhibition of sodium-hydrogen exchange reduces infarct size in the isolated rat heart--a protective additive to ischaemic preconditioning.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Male; Myocardial Infarction; Myocardial Ischemia; Myocar | 1995 |
31P NMR and triple quantum filtered 23Na NMR studies of the effects of inhibition of Na+/H+ exchange on intracellular sodium and pH in working and ischemic hearts.
Topics: Acidosis; Amiloride; Animals; Biological Transport, Active; Cardiac Output; Coronary Circulation; En | 1994 |
Na+/H+ exchange and reperfusion arrhythmias: protection by intracoronary infusion of a novel inhibitor.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardi | 1994 |
NMR measurements of Na+ and cellular energy in ischemic rat heart: role of Na(+)-H+ exchange.
Topics: Amiloride; Animals; Energy Metabolism; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; | 1993 |
Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia.
Topics: Adenosine Triphosphate; Amiloride; Anesthesia; Animals; Blood Platelets; Cattle; Endothelium, Vascul | 1993 |
Angiotensin II stimulates sodium-dependent proton extrusion in perfused ferret heart.
Topics: Alkalosis; Amiloride; Angiotensin II; Animals; Bicarbonates; Female; Ferrets; Hydrogen-Ion Concentra | 1996 |
Protective effect of the sodium/hydrogen exchange inhibitors during global low-flow ischemia.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cardiac Output; Energy Metabolism; Guanidines; Heart; In | 1996 |
Short-term inhibition of the Na-H exchanger limits acidosis and reduces ischemic injury in the rat heart.
Topics: Acidosis; Adenosine Triphosphate; Amiloride; Ammonium Chloride; Animals; Anti-Arrhythmia Agents; Hyd | 1997 |
Ethylisopropylamiloride diminishes changes in intracellular Na, Ca and pH in ischemic newborn myocardium.
Topics: Adenosine Triphosphate; Age Factors; Amiloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; C | 1997 |
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydroge | 1998 |
Influence of Bretschneider's cardioplegia on norepinephrine release from isolated perfused guinea-pig hearts.
Topics: Adrenergic Uptake Inhibitors; Amiloride; Animals; Desipramine; Dose-Response Relationship, Drug; Fev | 1999 |
LLC-PK(1) cells stably expressing the human norepinephrine transporter: A functional model of carrier-mediated norepinephrine release in protracted myocardial ischemia.
Topics: 1-Methyl-4-phenylpyridinium; Amiloride; Animals; Biological Transport, Active; Desipramine; Drug Int | 1999 |
Cardioprotection of SM-15681, an Na+/H+ exchange inhibitor in ischemic and hypoxic isolated perfused rat hearts.
Topics: Amides; Amiloride; Animals; Anti-Arrhythmia Agents; Hydrogen; Indoles; Ion Transport; Myocardial Isc | 1999 |
Inhibition of NHE protects reoxygenated cardiomyocytes independently of anoxic Ca(2+) overload and acidosis.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Calcium; Carrier Proteins; Cell Hypoxia; Cells, Cultured | 2000 |
Effect of SMP-300, a new Na+/H+ exchange inhibitor, on myocardial ischemia and experimental angina models in rats.
Topics: Amiloride; Angina Pectoris; Animals; Azocines; Blood Pressure; Disease Models, Animal; Electrocardio | 2000 |
Na+-overload during ischemia and reperfusion in rat hearts: comparison of the Na+/H+-exchange blockers EIPA, HOE642 and EMD96785.
Topics: Amiloride; Animals; Guanidines; In Vitro Techniques; Magnetic Resonance Spectroscopy; Myocardial Isc | 2000 |
Protective effect of SM-20550, a selective Na+ - H+ exchange inhibitor, on ischemia-reperfusion-injured hearts.
Topics: Adenosine Triphosphate; Amidines; Amiloride; Animals; Calcium; Female; Guinea Pigs; Hydrogen-Ion Con | 2001 |
Mitochondrial damage during ischemia determines post-ischemic contractile dysfunction in perfused rat heart.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Cytochrome c Group; In Vitro Techniques; Male; Membrane | 2002 |
Effects of Na+/H+ exchange inhibitors in cardiac ischemia.
Topics: Amiloride; Animals; Carrier Proteins; Erythrocytes; Hydrogen; In Vitro Techniques; Ion Transport; Ma | 1992 |