ethylisopropylamiloride has been researched along with Breast Cancer in 8 studies
ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using two human (MCF7, MDA-MB231) and one murine (EMT6) breast cancer cell lines, we evaluated the influence of two new agents, cariporide (an inhibitor of the Na(+)/H(+) antiport) and S3705 (an inhibitor of the Na(+)-dependent Cl(-)/HCO(3)(-) exchanger) on the regulation of intracellular pH (pHi)." | 3.71 | Cytostatic potential of novel agents that inhibit the regulation of intracellular pH. ( Kleemann, HW; Tannock, IF; Wong, P, 2002) |
| " We have investigated the role of plasma-membrane potential (DeltaPsipm) in putrescine and spermidine uptake in ZR-75-1 human breast cancer cells." | 3.70 | Dependence of mammalian putrescine and spermidine transport on plasma-membrane potential: identification of an amiloride binding site on the putrescine carrier. ( Audette, M; Charest-Gaudreault, R; Poulin, R; Verma, S; Zhao, C, 1998) |
| "Human breast cancer MCF-7, and nasopharyngeal carcinoma CNE-1 cell lines were heated at 43 degrees C under extracellular pH (pHe) conditions of 7." | 1.30 | Intracellular pH and heat sensitivity in two human cancer cell lines. ( Li, JH; Liu, FF, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Delpeut, S | 1 |
| Sisson, G | 1 |
| Black, KM | 1 |
| Richardson, CD | 1 |
| Lauritzen, G | 1 |
| Stock, CM | 1 |
| Lemaire, J | 1 |
| Lund, SF | 1 |
| Jensen, MF | 1 |
| Damsgaard, B | 1 |
| Petersen, KS | 1 |
| Wiwel, M | 1 |
| Rønnov-Jessen, L | 1 |
| Schwab, A | 1 |
| Pedersen, SF | 1 |
| Serafino, A | 1 |
| Moroni, N | 1 |
| Psaila, R | 1 |
| Zonfrillo, M | 1 |
| Andreola, F | 1 |
| Wannenes, F | 1 |
| Mercuri, L | 1 |
| Rasi, G | 1 |
| Pierimarchi, P | 1 |
| Bourguignon, LY | 1 |
| Singleton, PA | 1 |
| Diedrich, F | 1 |
| Stern, R | 1 |
| Gilad, E | 1 |
| Li, JH | 1 |
| Liu, FF | 1 |
| Poulin, R | 1 |
| Zhao, C | 1 |
| Verma, S | 1 |
| Charest-Gaudreault, R | 1 |
| Audette, M | 1 |
| Lee, AH | 1 |
| Tannock, IF | 2 |
| Wong, P | 1 |
| Kleemann, HW | 1 |
8 other studies available for ethylisopropylamiloride and Breast Cancer
| Article | Year |
|---|---|
Measles Virus Enters Breast and Colon Cancer Cell Lines through a PVRL4-Mediated Macropinocytosis Pathway.
Topics: Actins; Amiloride; Animals; Breast Neoplasms; Cell Adhesion Molecules; Cell Line; Chlorocebus aethio | 2017 |
The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2.
Topics: Amiloride; Benzamides; Breast Neoplasms; Cation Transport Proteins; Cell Adhesion; Cell Line, Tumor; | 2012 |
Anti-proliferative effect of atrial natriuretic peptide on colorectal cancer cells: evidence for an Akt-mediated cross-talk between NHE-1 activity and Wnt/β-catenin signaling.
Topics: Adenocarcinoma; Amiloride; Animals; Atrial Natriuretic Factor; beta Catenin; Breast Neoplasms; Cell | 2012 |
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion.
Topics: Amides; Amiloride; Animals; Breast Neoplasms; Cathepsin B; Caveolin 1; Caveolins; Cell Line, Tumor; | 2004 |
Intracellular pH and heat sensitivity in two human cancer cell lines.
Topics: Amiloride; Antiporters; Breast Neoplasms; Cell Survival; Female; Humans; Hydrogen-Ion Concentration; | 1997 |
Dependence of mammalian putrescine and spermidine transport on plasma-membrane potential: identification of an amiloride binding site on the putrescine carrier.
Topics: Amiloride; Animals; Binding Sites; Biological Transport; Breast Neoplasms; Carbonyl Cyanide m-Chloro | 1998 |
Heterogeneity of intracellular pH and of mechanisms that regulate intracellular pH in populations of cultured cells.
Topics: Amiloride; Animals; Antiporters; Bicarbonates; Breast Neoplasms; Chloride-Bicarbonate Antiporters; C | 1998 |
Cytostatic potential of novel agents that inhibit the regulation of intracellular pH.
Topics: Adenocarcinoma; Amiloride; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Chloride | 2002 |