ethylisopropylamiloride has been researched along with Acidosis in 22 studies
ethylisopropylamiloride: structure in first source
ethylisopropylamiloride : A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cultured cerebellar granule neurons (CGNs) are resistant to the toxic effect of ZnCl2 (0." | 5.42 | Acidosis and 5-(N-ethyl-N-isopropyl)amiloride (EIPA) Attenuate Zinc/Kainate Toxicity in Cultured Cerebellar Granule Neurons. ( Amelkina, GA; Genrikhs, EE; Isaev, NK; Ivashkin, EG; Khaspekov, LG; Novikova, SV; Stelmashook, EV, 2015) |
| "Cultured cerebellar granule neurons (CGNs) are resistant to the toxic effect of ZnCl2 (0." | 1.42 | Acidosis and 5-(N-ethyl-N-isopropyl)amiloride (EIPA) Attenuate Zinc/Kainate Toxicity in Cultured Cerebellar Granule Neurons. ( Amelkina, GA; Genrikhs, EE; Isaev, NK; Ivashkin, EG; Khaspekov, LG; Novikova, SV; Stelmashook, EV, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 11 (50.00) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stelmashook, EV | 1 |
| Novikova, SV | 1 |
| Amelkina, GA | 1 |
| Ivashkin, EG | 1 |
| Genrikhs, EE | 1 |
| Khaspekov, LG | 1 |
| Isaev, NK | 1 |
| Wang, Y | 1 |
| Weiss, MT | 1 |
| Yin, J | 1 |
| Frew, R | 1 |
| Tenn, C | 1 |
| Nelson, PP | 1 |
| Vair, C | 1 |
| Sawyer, TW | 1 |
| Twombley, K | 1 |
| Gattineni, J | 1 |
| Bobulescu, IA | 1 |
| Dwarakanath, V | 1 |
| Baum, M | 1 |
| Amemiya, M | 1 |
| Mori, H | 1 |
| Imamura, S | 1 |
| Toyoda, A | 1 |
| Funayama, I | 1 |
| Asano, Y | 1 |
| Kusano, E | 1 |
| Tabei, K | 1 |
| Schneider, D | 1 |
| Gerhardt, E | 1 |
| Bock, J | 1 |
| Müller, MM | 1 |
| Wolburg, H | 1 |
| Lang, F | 1 |
| Schulz, JB | 1 |
| Sipos, H | 1 |
| Törocsik, B | 1 |
| Tretter, L | 1 |
| Adam-Vizi, V | 1 |
| Zamzow, CR | 1 |
| Bose, R | 1 |
| Parkinson, FE | 1 |
| Huck, V | 1 |
| Niemeyer, A | 1 |
| Goerge, T | 1 |
| Schnaeker, EM | 1 |
| Ossig, R | 1 |
| Rogge, P | 1 |
| Schneider, MF | 1 |
| Oberleithner, H | 1 |
| Schneider, SW | 1 |
| Navon, G | 1 |
| Werrmann, JG | 1 |
| Maron, R | 1 |
| Cohen, SM | 1 |
| Kovacic, H | 1 |
| Gallice, P | 1 |
| Sarrazin, M | 1 |
| Crevat, A | 1 |
| Shi, H | 1 |
| Hamm, PH | 1 |
| Meyers, RS | 1 |
| Lawler, RG | 1 |
| Jackson, DC | 1 |
| Schaefer, S | 2 |
| Ramasamy, R | 2 |
| Rehring, TF | 1 |
| Shapiro, JI | 1 |
| Cain, BS | 1 |
| Meldrum, DR | 1 |
| Cleveland, JC | 1 |
| Harken, AH | 1 |
| Banerjee, A | 1 |
| Lane, M | 1 |
| Baltz, JM | 1 |
| Bavister, BD | 1 |
| Chiu, HM | 1 |
| Lin, HH | 1 |
| Tang, MJ | 1 |
| Müller, F | 1 |
| Aschenbach, JR | 1 |
| Gäbel, G | 1 |
| Phillis, JW | 1 |
| Ren, J | 1 |
| O'Regan, MH | 1 |
| Gambassi, G | 1 |
| Carbonin, P | 1 |
| Capogrossi, MC | 1 |
| Moe, OW | 1 |
| Miller, RT | 1 |
| Horie, S | 1 |
| Cano, A | 1 |
| Preisig, PA | 1 |
| Alpern, RJ | 1 |
| Ghysel-Burton, J | 1 |
| Godfraind, T | 1 |
| Simon, EE | 1 |
| Merli, C | 1 |
| Herndon, J | 1 |
| Cragoe, EJ | 1 |
| Hamm, LL | 1 |
22 other studies available for ethylisopropylamiloride and Acidosis
| Article | Year |
|---|---|
Acidosis and 5-(N-ethyl-N-isopropyl)amiloride (EIPA) Attenuate Zinc/Kainate Toxicity in Cultured Cerebellar Granule Neurons.
Topics: Acidosis; Amiloride; Animals; Calcium; Cations, Divalent; Cell Death; Cells, Cultured; Cerebellum; C | 2015 |
Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons.
Topics: Acidosis; Amiloride; Animals; Antimetabolites, Antineoplastic; Calcium; Cell Death; Cell Survival; C | 2009 |
Effect of metabolic acidosis on neonatal proximal tubule acidification.
Topics: Acidosis; Adaptation, Physiological; Amiloride; Animals; Animals, Newborn; Bicarbonates; Disease Mod | 2010 |
Stimulation of NHE3 in OKP cells by an autocrine mechanism.
Topics: Acidosis; Amiloride; Angiotensin II; Animals; Autocrine Communication; Benzoquinones; Cell Line; Cul | 2004 |
Intracellular acidification by inhibition of the Na+/H+-exchanger leads to caspase-independent death of cerebellar granule neurons resembling paraptosis.
Topics: Acidosis; Adenoviridae; Amiloride; Animals; Apoptosis; Caspases; Cell Survival; Cells, Cultured; Cer | 2004 |
Impaired regulation of pH homeostasis by oxidative stress in rat brain capillary endothelial cells.
Topics: Acidosis; Amiloride; Ammonium Chloride; Animals; Blood-Brain Barrier; Buffers; Cells, Cultured; Cult | 2005 |
The effect of acidosis on adenosine release from cultured rat forebrain neurons.
Topics: Acetates; Acidosis; Adenosine; Amiloride; Analysis of Variance; Animals; Cells, Cultured; Dose-Respo | 2006 |
Delay of acute intracellular pH recovery after acidosis decreases endothelial cell activation.
Topics: Acidosis; Amiloride; Calcium; Cell Adhesion; Cells, Cultured; Chloride-Bicarbonate Antiporters; Cycl | 2007 |
31P NMR and triple quantum filtered 23Na NMR studies of the effects of inhibition of Na+/H+ exchange on intracellular sodium and pH in working and ischemic hearts.
Topics: Acidosis; Amiloride; Animals; Biological Transport, Active; Cardiac Output; Coronary Circulation; En | 1994 |
Chloride dependent intracellular pH increase induced by bepridil in human red blood cells: a possible involvement in correction of ischemic acidosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Bepridil; Calcium; Carbonic A | 1993 |
Mechanisms of pHi recovery from NH4Cl-induced acidosis in anoxic isolated turtle heart: a 31P-NMR study.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Ammonium Chloride; Animals; B | 1997 |
Short-term inhibition of the Na-H exchanger limits acidosis and reduces ischemic injury in the rat heart.
Topics: Acidosis; Adenosine Triphosphate; Amiloride; Ammonium Chloride; Animals; Anti-Arrhythmia Agents; Hyd | 1997 |
Mechanisms of pH preservation during global ischemia in preconditioned rat heart: roles for PKC and NHE.
Topics: Acidosis; Adenosine Triphosphate; Adrenergic alpha-Agonists; Amiloride; Animals; Guanidines; Hydroge | 1998 |
Regulation of intracellular pH in hamster preimplantation embryos by the sodium hydrogen (Na+/H+) antiporter.
Topics: Acid-Base Equilibrium; Acidosis; Amiloride; Animals; Antiporters; Chloride-Bicarbonate Antiporters; | 1998 |
Ethyl isopropylamiloride downregulates Na,K-ATPase gene expression which confers cytotoxicity in primary proximal tubule cell cultures.
Topics: Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Blotting, Northern; Cell Survival; Cells, Cult | 1998 |
Inhibition of Na+-H+ exchanger protects diabetic and non-diabetic hearts from ischemic injury: insight into altered susceptibility of diabetic hearts to ischemic injury.
Topics: Acidosis; Adenosine Triphosphate; Amiloride; Animals; Calcium; Diabetes Mellitus, Type 1; Hydrogen-I | 1999 |
Role of Na+/H+ exchange and HCO3- transport in pHi recovery from intracellular acid load in cultured epithelial cells of sheep rumen.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis; Amiloride; Animals; Anti-Arrhythmia Agen | 2000 |
Inhibition of Na(+)/H(+) exchange by 5-(N-ethyl-N-isopropyl)-amiloride reduces free fatty acid efflux from the ischemic reperfused rat cerebral cortex.
Topics: Acidosis; Amiloride; Animals; Brain Ischemia; Cardiovascular Physiological Phenomena; Cerebral Corte | 2000 |
[The arrhythmogenicity of alpha 1-adrenergic stimulation following myocardial acidosis].
Topics: Acidosis; Amiloride; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyrans; Cardiomyopa | 1992 |
Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts.
Topics: Acidosis; Amiloride; Animals; Carrier Proteins; Cells, Cultured; Epithelium; Kidney; Mice; Phosphoen | 1991 |
Role of Na-H exchange in the inotropic action of Bay K 8644 and of ouabain in guinea-pig isolated atria.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Determinants of ammonia entry along the rat proximal tubule during chronic metabolic acidosis.
Topics: Acidosis; Amiloride; Ammonia; Animals; Bicarbonates; Kidney Tubules, Proximal; Perfusion; Rats; Rats | 1989 |