ethylhexylglycerin and Dermatitis--Allergic-Contact

Ethylhexylglycerin is a relatively new cosmetic ingredient that is used for its surfactant, emollient, skin-conditioning and antimicrobial properties. Since 2002, it has been occasionally reported as a contact allergen.. To report on 13 patients who presented with allergic contact dermatitis caused by ethylhexylglycerin, evaluated at two Belgian university patch test clinics during the period 1990-2015.. The patients were patch tested with the European baseline series, a cosmetic series, and - if indicated - additional series. Both the cosmetic products used and their single ingredients were patch tested.. All but one of the ethylhexylglycerin-allergic patients were female, with a median age of 43 years (range: 29-81 years), most often suffering from dermatitis on the face, and sometimes on the hands and/or axillae. As the culprit products, leave-on cosmetics were identified, including a high number of proclaimed 'hypo-allergenic' and 'preservative-free' facial creams, sun protection creams, and deodorants.. Ethylhexylglycerin is a rare, but highly relevant, cosmetic sensitizer, even in those products advertised to be safe for consumers. Targeted patch testing with ethylhexylglycerin 5% pet. is very useful, and routine patch testing in a cosmetic series may be considered. Higher test concentrations might be indicated in selected cases.

Topics: Adult; Aged; Aged, 80 and over; Belgium; Cosmetics; Dermatitis, Allergic Contact; Female; Glyceryl Ethers; Humans; Middle Aged; Patch Tests; Product Labeling

Topics: Aerosols; Dermatitis, Allergic Contact; Female; Glyceryl Ethers; Hand Dermatoses; Humans; Middle Aged; Ointments

Topics: Aged; Cosmetics; Dermatitis, Allergic Contact; Facial Dermatoses; Female; Glyceryl Ethers; Glycols; Humans; Preservatives, Pharmaceutical

Topics: Administration, Topical; Dermatitis, Allergic Contact; Female; Glyceryl Ethers; Humans; Middle Aged; Patch Tests; Preservatives, Pharmaceutical; Sunscreening Agents