ethylene glycol has been researched along with Uremia in 3 studies
Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ethylene glycol intoxication was confirmed in 37 dogs." | 1.29 | Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996) |
| "Neither adverse clinical signs nor clinicopathologic abnormalities were associated with the administration of 4-MP except in 1 dog, which developed tachypnea, gagging, excess salivation, and trembling after the second dose of 4-MP was given." | 1.29 | Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996) |
| "4-MP was a safe and effective treatment for EG intoxication when it was given before sufficient quantities of EG had been metabolized to induce renal failure." | 1.29 | Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996) |
| "For dogs treated with 4-MP, 1 of 2 dosage regimens was usually used: 20 mg/kg of body weight, IV, initially, 15 mg/kg 17 hours later, and 5 mg/kg 25 and 36 hours after the initial dose, or 20 mg/kg, IV, initially, 15 mg/kg 12 and 24 hours later, and 5 mg/kg 36 hours after the initial dose." | 1.29 | Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Schantl, AE | 1 |
| Verhulst, A | 1 |
| Neven, E | 1 |
| Behets, GJ | 1 |
| D'Haese, PC | 1 |
| Maillard, M | 1 |
| Mordasini, D | 1 |
| Phan, O | 1 |
| Burnier, M | 1 |
| Spaggiari, D | 1 |
| Decosterd, LA | 1 |
| MacAskill, MG | 1 |
| Alcaide-Corral, CJ | 1 |
| Tavares, AAS | 1 |
| Newby, DE | 1 |
| Beindl, VC | 1 |
| Maj, R | 1 |
| Labarre, A | 1 |
| Hegde, C | 1 |
| Castagner, B | 1 |
| Ivarsson, ME | 1 |
| Leroux, JC | 1 |
| Radlović, O | 1 |
| Radmilović, A | 1 |
| Stanković, N | 1 |
| Mirković, M | 1 |
| Connally, HE | 1 |
| Thrall, MA | 1 |
| Forney, SD | 1 |
| Grauer, GF | 1 |
| Hamar, DW | 1 |
3 other studies available for ethylene glycol and Uremia
| Article | Year |
|---|---|
Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers.
Topics: 6-Phytase; Adenine; Animals; Cells, Cultured; Drug Evaluation, Preclinical; Dynamic Light Scattering | 2020 |
[Acute uremia due to ethylene glycol poisoning (antifreeze)].
Topics: Acute Disease; Adult; Ethylene Glycol; Ethylene Glycols; Humans; Male; Uremia | 1984 |
Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995).
Topics: Acid-Base Equilibrium; Alcohol Dehydrogenase; Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Ethyle | 1996 |