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ethylene glycol and Uremia

ethylene glycol has been researched along with Uremia in 3 studies

Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.

Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.

Research Excerpts

ExcerptRelevanceReference
"Ethylene glycol intoxication was confirmed in 37 dogs."1.29Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996)
"Neither adverse clinical signs nor clinicopathologic abnormalities were associated with the administration of 4-MP except in 1 dog, which developed tachypnea, gagging, excess salivation, and trembling after the second dose of 4-MP was given."1.29Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996)
"4-MP was a safe and effective treatment for EG intoxication when it was given before sufficient quantities of EG had been metabolized to induce renal failure."1.29Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996)
"For dogs treated with 4-MP, 1 of 2 dosage regimens was usually used: 20 mg/kg of body weight, IV, initially, 15 mg/kg 17 hours later, and 5 mg/kg 25 and 36 hours after the initial dose, or 20 mg/kg, IV, initially, 15 mg/kg 12 and 24 hours later, and 5 mg/kg 36 hours after the initial dose."1.29Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995). ( Connally, HE; Forney, SD; Grauer, GF; Hamar, DW; Thrall, MA, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Schantl, AE1
Verhulst, A1
Neven, E1
Behets, GJ1
D'Haese, PC1
Maillard, M1
Mordasini, D1
Phan, O1
Burnier, M1
Spaggiari, D1
Decosterd, LA1
MacAskill, MG1
Alcaide-Corral, CJ1
Tavares, AAS1
Newby, DE1
Beindl, VC1
Maj, R1
Labarre, A1
Hegde, C1
Castagner, B1
Ivarsson, ME1
Leroux, JC1
Radlović, O1
Radmilović, A1
Stanković, N1
Mirković, M1
Connally, HE1
Thrall, MA1
Forney, SD1
Grauer, GF1
Hamar, DW1

Other Studies

3 other studies available for ethylene glycol and Uremia

ArticleYear
Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers.
    Nature communications, 2020, 02-05, Volume: 11, Issue:1

    Topics: 6-Phytase; Adenine; Animals; Cells, Cultured; Drug Evaluation, Preclinical; Dynamic Light Scattering

2020
[Acute uremia due to ethylene glycol poisoning (antifreeze)].
    Srpski arhiv za celokupno lekarstvo, 1984, Volume: 112, Issue:2

    Topics: Acute Disease; Adult; Ethylene Glycol; Ethylene Glycols; Humans; Male; Uremia

1984
Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs: 107 cases (1983-1995).
    Journal of the American Veterinary Medical Association, 1996, Dec-01, Volume: 209, Issue:11

    Topics: Acid-Base Equilibrium; Alcohol Dehydrogenase; Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Ethyle

1996