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ethylene glycol and Necrosis

ethylene glycol has been researched along with Necrosis in 6 studies

Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"A case of corrosion and necrosis of the esophagus and stomach after ingestion of fluid containing copper sulfate, ethylene glycol and methanol is presented."7.67Copper sulfate corrosion and necrosis of the esophagus and stomach. Case report. ( Auvinen, O; Isolauri, J; Markkula, H, 1986)
" ROLE OF METABOLITES: Although the "aldehyde" metabolites of EG, glycolaldehyde, and glyoxalate, have been suggested as the metabolites responsible, recent studies have shown definitively that the accumulation of calcium oxalate monohydrate (COM) crystals in kidney tissue produces renal tubular necrosis that leads to kidney failure."4.85Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning? ( McMartin, K, 2009)
"Formation of calcium oxalate (CaOx) kidney stones was investigated using three approaches."4.80Nephrolithiasis: a consequence of renal epithelial cell exposure to oxalate and calcium oxalate crystals. ( Khan, SR; Thamilselvan, S, 2000)
"The severity of ethylene glycol toxicity is related to the metabolic acidosis resulting from the biotransformation of ethylene glycol into toxic metabolites."3.74Calcium oxalate crystals in acute ethylene glycol poisoning: a confocal laser scanning microscope study in a fatal case. ( D'Errico, S; Fineschi, V; Fiore, C; Pomara, C; Riezzo, I, 2008)
"The histologic diagnosis of acute renal failure secondary to ethylene glycol poisoning depends on the recognitions of the changes of acute tubular damage in association with calcium oxalate crystals deposition within the tubular epithelial cells and the widespread necrosis of the tubular epithelium in the proximal tubules."3.74Calcium oxalate crystals in acute ethylene glycol poisoning: a confocal laser scanning microscope study in a fatal case. ( D'Errico, S; Fineschi, V; Fiore, C; Pomara, C; Riezzo, I, 2008)
"A case of corrosion and necrosis of the esophagus and stomach after ingestion of fluid containing copper sulfate, ethylene glycol and methanol is presented."3.67Copper sulfate corrosion and necrosis of the esophagus and stomach. Case report. ( Auvinen, O; Isolauri, J; Markkula, H, 1986)
"Sustained hyperoxaluria in association with CaOx crystals induced apoptosis as well as necrosis."2.41Nephrolithiasis: a consequence of renal epithelial cell exposure to oxalate and calcium oxalate crystals. ( Khan, SR; Thamilselvan, S, 2000)
"The histologic diagnosis of acute renal failure secondary to ethylene glycol poisoning depends on the recognitions of the changes of acute tubular damage in association with calcium oxalate crystals deposition within the tubular epithelial cells and the widespread necrosis of the tubular epithelium in the proximal tubules."1.35Calcium oxalate crystals in acute ethylene glycol poisoning: a confocal laser scanning microscope study in a fatal case. ( D'Errico, S; Fineschi, V; Fiore, C; Pomara, C; Riezzo, I, 2008)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ruimy, A1
Keyser, M1
Pottecher, J1
Kremer, S1
Diemunsch, P1
McMartin, K1
Reddy, NJ1
Lewis, LD1
Gardner, TB1
Osterling, W1
Eskey, CJ1
Nierenberg, DW1
Pomara, C1
Fiore, C1
D'Errico, S1
Riezzo, I1
Fineschi, V1
Khan, SR1
Thamilselvan, S1
Isolauri, J1
Markkula, H1
Auvinen, O1

Reviews

2 reviews available for ethylene glycol and Necrosis

ArticleYear
Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?
    Clinical toxicology (Philadelphia, Pa.), 2009, Volume: 47, Issue:9

    Topics: Acute Kidney Injury; Animals; Calcium Oxalate; Crystallization; Ethylene Glycol; Humans; Kidney Tubu

2009
Nephrolithiasis: a consequence of renal epithelial cell exposure to oxalate and calcium oxalate crystals.
    Molecular urology, 2000,Winter, Volume: 4, Issue:4

    Topics: Animals; Calcium Oxalate; Cell Aggregation; Cell Line; Crystallization; Dogs; Ethylene Glycol; Human

2000

Other Studies

4 other studies available for ethylene glycol and Necrosis

ArticleYear
[Extensive brain necrosis secondary to acute ethylene glycol poisoning].
    Annales francaises d'anesthesie et de reanimation, 2014, Volume: 33, Issue:6

    Topics: Acidosis; Brain Diseases; Brain Injuries; Ethylene Glycol; Fatal Outcome; Hemodiafiltration; Humans;

2014
Two cases of rapid onset Parkinson's syndrome following toxic ingestion of ethylene glycol and methanol.
    Clinical pharmacology and therapeutics, 2007, Volume: 81, Issue:1

    Topics: Acute Disease; Adult; Aged; Antiparkinson Agents; Basal Ganglia; Carbidopa; Ethylene Glycol; Female;

2007
Calcium oxalate crystals in acute ethylene glycol poisoning: a confocal laser scanning microscope study in a fatal case.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:4

    Topics: Acidosis; Acute Kidney Injury; Adult; Biotransformation; Calcium Oxalate; Ethylene Glycol; Fatal Out

2008
Copper sulfate corrosion and necrosis of the esophagus and stomach. Case report.
    Acta chirurgica Scandinavica, 1986, Volume: 152

    Topics: Adult; Copper; Copper Sulfate; Esophagus; Ethylene Glycol; Ethylene Glycols; Humans; Male; Methanol;

1986