Page last updated: 2024-10-16

ethylene glycol and Hyperoxaluria

ethylene glycol has been researched along with Hyperoxaluria in 51 studies

Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.

Hyperoxaluria: Excretion of an excessive amount of OXALATES in the urine.

Research Excerpts

ExcerptRelevanceReference
" Most of the studies used ethylene glycol (EG) to induce hyperoxaluria and nephrolithiasis in rats."9.12Antiurolithic effects of medicinal plants: results of in vivo studies in rat models of calcium oxalate nephrolithiasis-a systematic review. ( Bashir, S; Khan, A; Khan, SR, 2021)
"75 percent ethylene glycol (v/v) in their drinking water for six weeks to induce hyperoxaluria."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Weight loss, serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation and kidney histopathological studies were done."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Weight loss, rise of serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation were all shown to be prevented by the addition of atorvastatin, polysaccharides, or aqueous extract, respectively."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Ulvan infusions (100 mg/kg body weight), ulvan polysaccharides (100 mg/kg body weight), and atorvastatin (two milligrams/kg body weight) to treat hyperoxaluric rats for four weeks (every other day) were used."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" The rats were randomized into three groups: Group 1 consisted of the controls (n = 8), Group 2 of hyperoxaluria (1% ethylene glycol (EG), n = 8), and Group 3 of the treatment (1% EG + 10 mg/kg of RES, n = 8) group."7.85Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017)
"In the present study, resveratrol was seen to prevent hyperoxaluria."7.85Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017)
"To investigate whether the sex-dependent expression of hepatic and renal oxalate transporter sat-1 (Slc26a1) changes in a rat model of ethylene glycol (EG)-induced hyperoxaluria."7.81In female rats, ethylene glycol treatment elevates protein expression of hepatic and renal oxalate transporter sat-1 (Slc26a1) without inducing hyperoxaluria. ( Breljak, D; Brzica, H; Burckhardt, BC; Burckhardt, G; Henjakovic, M; Jurasović, J; Karaica, D; Ljubojević, M; Lovrić, M; Micek, V; Peraica, M; Rašić, D; Sabolić, I; Schnedler, N; Sekovanić, A; Vrhovac, I; Wegner, W, 2015)
"Oral administration of ethylene glycol resulted in hyperoxaluria and increased renal excretion of calcium and phosphate."7.78Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012)
" In groups 1A, 1B and 1C hyperoxaluria was induced with ethylene glycol for 2 weeks."7.76Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"Increased systemic and local tissue asymmetrical dimethylarginine may help explain the pathogenetic mechanisms of hyperoxaluria induced disorders such as nephrolithiasis and atherosclerosis."7.76Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
" (HARC) against ethylene glycol induced urolithiasis and its possible underlying mechanisms using male Wistar albino rats."7.76Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010)
"Indicate that the HARC can protect against ethylene glycol induced urolithiasis as it reduced and prevented the growth of urinary stones."7.76Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010)
"The present study was undertaken to explore the efficiency of the pentacyclic triterpene lupeol (1) and its ester derivative, lupeol linoleate (2), in experimental hyperoxaluria."7.74Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008)
"Ethylene glycol (EG) consumption is commonly employed as an experimental regimen to induce hyperoxaluria in animal models of calcium oxalate nephrolithiasis."7.73Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005)
" Ethylene glycol feeding resulted in hyperoxaluria as well as increased renal excretion of calcium and phosphate."7.73Effect of Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats. ( Alagawadi, KR; Gadge, NB; Karadi, RV; Savadi, RV, 2006)
"Hyperoxaluria was produced in rats by ethylene glycol in drinking water."7.69Lipid peroxidation in ethylene glycol induced hyperoxaluria and calcium oxalate nephrolithiasis. ( Hackett, RL; Khan, SR; Thamilselvan, S, 1997)
"Ethylene glycol is a toxic alcohol which may induce significant toxicity when ingested accidentally or intentionally."6.72The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review. ( Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C, 2021)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."5.91The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"We found that EG not only resulted hyperoxaluria and kidney stone formation, but also promoted the intestinal inflammation, elevated intestinal permeability, and gut microbiota disorders."5.62Probiotic Lactiplantibacillus plantarum N-1 could prevent ethylene glycol-induced kidney stones by regulating gut microbiota and enhancing intestinal barrier function. ( Cui, Y; Jin, X; Li, H; Liu, Y; Sun, Q; Tian, L; Wang, K; Wei, Z; Yu, Y, 2021)
"Hyperoxaluria is characterized by an increased excretion of urinary oxalate which is caused by inherited disorders or high oxalate intake leading to renal stone ailment."5.51Amelioration of hyperoxaluria-induced kidney dysfunction by chemical chaperone 4-phenylbutyric acid. ( Bhardwaj, R; Kaur, T; Randhawa, R, 2019)
"In the hyperoxaluria group, urinary oxalate levels were higher than the control group; yet, lower in the treatment group compared to hyperoxaluria group (p < 0."5.46Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017)
"Treatment of ethylene glycol intoxication is based on specific inhibitors of alcohol dehydrogenase and hemodialysis in the most severe forms, and should be started promptly."5.39[Secondary hyperoxaluria and nephrocalcinosis due to ethylene glycol poisoning]. ( Harambat, J; Llanas, B; Missonnier, S; Monet, C; Rebouissoux, L; Richard, E, 2013)
"Calcium oxalate lithiasis was induced in rats by oral administration of 0."5.38Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012)
"Drawbacks of presently available treatments for urolithiasis necessitate finding the treatment of hyperoxaluria specifically aimed at reduction in oxalate excretion."5.38Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012)
"There is some evidence that hyperoxaluria may effect vascular endothelium and many studies link renal stones to atherosclerosis."5.36Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"In groups 1A, 1B and 1C hyperoxaluria was induced with ethylene glycol for 2 weeks."5.36Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"Hyperoxaluria induced a significantly dense staining pattern in renal tissue asymmetrical dimethylarginine vs controls (p = 0."5.36Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"Hyperoxaluria was induced in male Wistar rats with 0."5.35Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008)
"Frank metabolic acidosis was observed in the MA rats: decreased arterial pH and plasma HCO3(-) concentration with lower urinary pH and citrate excretion with elevated excretion of ammonium, phosphate and, hence, titratable acid."5.33Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005)
"Mild hyperoxaluria was induced in male Wistar rats using ethylene glycol (EG; 0."5.33Mild tubular damage induces calcium oxalate crystalluria in a model of subtle hyperoxaluria: Evidence that a second hit is necessary for renal lithogenesis. ( D'Angelo, A; Del Prete, D; Della Barbera, M; Gambaro, G; Trevisan, A; Valente, ML; Zanetti, E, 2006)
"Hyperoxaluria was produced in rats by ethylene glycol in drinking water."5.30Lipid peroxidation in ethylene glycol induced hyperoxaluria and calcium oxalate nephrolithiasis. ( Hackett, RL; Khan, SR; Thamilselvan, S, 1997)
" Most of the studies used ethylene glycol (EG) to induce hyperoxaluria and nephrolithiasis in rats."5.12Antiurolithic effects of medicinal plants: results of in vivo studies in rat models of calcium oxalate nephrolithiasis-a systematic review. ( Bashir, S; Khan, A; Khan, SR, 2021)
"Formation of calcium oxalate (CaOx) kidney stones was investigated using three approaches."4.80Nephrolithiasis: a consequence of renal epithelial cell exposure to oxalate and calcium oxalate crystals. ( Khan, SR; Thamilselvan, S, 2000)
"75 percent ethylene glycol (v/v) in their drinking water for six weeks to induce hyperoxaluria."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Weight loss, serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation and kidney histopathological studies were done."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Weight loss, rise of serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation were all shown to be prevented by the addition of atorvastatin, polysaccharides, or aqueous extract, respectively."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Ulvan infusions (100 mg/kg body weight), ulvan polysaccharides (100 mg/kg body weight), and atorvastatin (two milligrams/kg body weight) to treat hyperoxaluric rats for four weeks (every other day) were used."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural system."3.88Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats. ( Albert, A; Ganesan, D; Govindan Sadasivam, S; Mariaraj Sivakumar, S; Paul, E; Ponnusamy, S; Prabhakaran, R; Tiwari, V, 2018)
" The rats were randomized into three groups: Group 1 consisted of the controls (n = 8), Group 2 of hyperoxaluria (1% ethylene glycol (EG), n = 8), and Group 3 of the treatment (1% EG + 10 mg/kg of RES, n = 8) group."3.85Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017)
"In the present study, resveratrol was seen to prevent hyperoxaluria."3.85Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017)
"Hyperoxaluria was induced in male SD rats by administering ethylene glycol."3.83Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016)
"To investigate whether the sex-dependent expression of hepatic and renal oxalate transporter sat-1 (Slc26a1) changes in a rat model of ethylene glycol (EG)-induced hyperoxaluria."3.81In female rats, ethylene glycol treatment elevates protein expression of hepatic and renal oxalate transporter sat-1 (Slc26a1) without inducing hyperoxaluria. ( Breljak, D; Brzica, H; Burckhardt, BC; Burckhardt, G; Henjakovic, M; Jurasović, J; Karaica, D; Ljubojević, M; Lovrić, M; Micek, V; Peraica, M; Rašić, D; Sabolić, I; Schnedler, N; Sekovanić, A; Vrhovac, I; Wegner, W, 2015)
"Oral administration of ethylene glycol resulted in hyperoxaluria and increased renal excretion of calcium and phosphate."3.78Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012)
"75% v/v ethylene glycol in drinking water to induce chronic hyperoxaluria and simultaneously BDE was given to nephrolithiasic treated rats at the dose of 100 and 200 mg/kg b."3.77Aqueous extract of Boerhaavia diffusa root ameliorates ethylene glycol-induced hyperoxaluric oxidative stress and renal injury in rat kidney. ( Mazumder, PM; Pareta, SK; Patra, KC; Sasmal, D, 2011)
" In groups 1A, 1B and 1C hyperoxaluria was induced with ethylene glycol for 2 weeks."3.76Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"Increased systemic and local tissue asymmetrical dimethylarginine may help explain the pathogenetic mechanisms of hyperoxaluria induced disorders such as nephrolithiasis and atherosclerosis."3.76Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
" (HARC) against ethylene glycol induced urolithiasis and its possible underlying mechanisms using male Wistar albino rats."3.76Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010)
"Indicate that the HARC can protect against ethylene glycol induced urolithiasis as it reduced and prevented the growth of urinary stones."3.76Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010)
"The present study was undertaken to explore the efficiency of the pentacyclic triterpene lupeol (1) and its ester derivative, lupeol linoleate (2), in experimental hyperoxaluria."3.74Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008)
"Ethylene glycol (EG) consumption is commonly employed as an experimental regimen to induce hyperoxaluria in animal models of calcium oxalate nephrolithiasis."3.73Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005)
"l-Arg could act as a potent antilithic agent, by increasing the level of citrate in the hyperoxaluria-induced rats and decreasing calcium oxalate binding to the THP."3.73Oral L-arginine supplementation ameliorates urinary risk factors and kinetic modulation of Tamm-Horsfall glycoprotein in experimental hyperoxaluric rats. ( Kalaiselvi, P; Pragasam, V; Srinivasan, S; Sumitra, K; Varalakshmi, P, 2005)
" Ethylene glycol feeding resulted in hyperoxaluria as well as increased renal excretion of calcium and phosphate."3.73Effect of Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats. ( Alagawadi, KR; Gadge, NB; Karadi, RV; Savadi, RV, 2006)
"Osteopontin expression in the kidneys was significantly increased after hyperoxaluria and it increased further after the deposition of calcium oxalate crystals in the kidneys."3.71Expression of osteopontin in rat kidneys: induction during ethylene glycol induced calcium oxalate nephrolithiasis. ( Cornelius, JG; Glenton, PA; Johnson, JM; Khan, SR; Peck, AB, 2002)
"To correlate serum glycolic acid levels with clinical severity and outcome in ethylene glycol poisoning and to determine if glycolic acid levels are predictive of renal failure and the need for hemodialysis."3.71Ethylene glycol toxicity: the role of serum glycolic acid in hemodialysis. ( Bush, BA; Dunnington, JE; Pappas, AA; Porter, WH; Rutter, PW, 2001)
" Hyperoxaluria was induced by feeding ethylene glycol (EG) in drinking water."3.70Role of glutathione on renal mitochondrial status in hyperoxaluria. ( Muthukumar, A; Selvam, R, 1998)
"Hyperoxaluria was produced in male Wistar rats by adding ethylene glycol to their drinking water."3.70Possible biphasic changes of free radicals in ethylene glycol-induced nephrolithiasis in rats. ( Chen, CF; Chen, J; Chien, CT; Huang, HS, 2000)
"Hyperoxaluria was produced in rats by ethylene glycol in drinking water."3.69Lipid peroxidation in ethylene glycol induced hyperoxaluria and calcium oxalate nephrolithiasis. ( Hackett, RL; Khan, SR; Thamilselvan, S, 1997)
"Ethylene glycol is a toxic alcohol which may induce significant toxicity when ingested accidentally or intentionally."2.72The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review. ( Ahmad, Y; Chiche, JD; Kissling, S; Liaudet, L; Ltaief, Z; Torrent, C, 2021)
"Sustained hyperoxaluria in association with CaOx crystals induced apoptosis as well as necrosis."2.41Nephrolithiasis: a consequence of renal epithelial cell exposure to oxalate and calcium oxalate crystals. ( Khan, SR; Thamilselvan, S, 2000)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."1.91The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"We found that EG not only resulted hyperoxaluria and kidney stone formation, but also promoted the intestinal inflammation, elevated intestinal permeability, and gut microbiota disorders."1.62Probiotic Lactiplantibacillus plantarum N-1 could prevent ethylene glycol-induced kidney stones by regulating gut microbiota and enhancing intestinal barrier function. ( Cui, Y; Jin, X; Li, H; Liu, Y; Sun, Q; Tian, L; Wang, K; Wei, Z; Yu, Y, 2021)
"Hyperoxaluria is well known to cause renal injury and end-stage kidney disease."1.56Alteration of the gut microbiota by vinegar is associated with amelioration of hyperoxaluria-induced kidney injury. ( Duan, X; He, Z; Lan, Y; Li, S; Liu, Y; Lu, S; Luo, L; Mai, X; Wu, C; Xiao, C; Yang, Z; Zeng, G; Zhang, X; Zhong, W; Zhu, W, 2020)
"Hyperoxaluria is characterized by an increased excretion of urinary oxalate which is caused by inherited disorders or high oxalate intake leading to renal stone ailment."1.51Amelioration of hyperoxaluria-induced kidney dysfunction by chemical chaperone 4-phenylbutyric acid. ( Bhardwaj, R; Kaur, T; Randhawa, R, 2019)
"Induction of hyperoxaluria in rats with MS causes severe morphological alterations with a significant impairment of renal function."1.48Metabolic syndrome contributes to renal injury mediated by hyperoxaluria in a murine model of nephrolithiasis. ( Carballido, J; Castillón, I; Corbacho, C; Coronado, MJ; Jorge, E; Prieto, D; Ramil, E; Sáenz-Medina, J; Sánchez, A; Santos, M; Soblechero, P; Virumbrales, E, 2018)
"Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural system."1.48Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats. ( Albert, A; Ganesan, D; Govindan Sadasivam, S; Mariaraj Sivakumar, S; Paul, E; Ponnusamy, S; Prabhakaran, R; Tiwari, V, 2018)
"Hyperoxaluria induces crystalluria, interstitial fibrosis, and progressive renal failure."1.46Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury. ( Borges, FT; Convento, MB; Cruz, E; da Glória, MA; Pessoa, EA; Schor, N, 2017)
"Hyperoxaluria was induced by adding hydroxyproline and ethylene glycol to the mice's drinking water for up to 60 days."1.46Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury. ( Borges, FT; Convento, MB; Cruz, E; da Glória, MA; Pessoa, EA; Schor, N, 2017)
"In the hyperoxaluria group, urinary oxalate levels were higher than the control group; yet, lower in the treatment group compared to hyperoxaluria group (p < 0."1.46Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017)
"Treatment with spironolactone reversed the effect of hyperoxaluria."1.43Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016)
"Hyperoxaluria was induced in male SD rats by administering ethylene glycol."1.43Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016)
"Results indicate that hyperoxaluria-induced production of ROS, injury and inflammation are in part associated with the activation of Nox through renin-angiotensin-aldosterone pathway."1.43Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016)
" In summary, pAA is a potent anti-urolithic agent in rats and we can propose that 10 mg/kg body weight is the effective dosage of pAA and this concentration can be used for further studies."1.43Polyacrylic acid attenuates ethylene glycol induced hyperoxaluric damage and prevents crystal aggregation in vitro and in vivo. ( Ganesh, RN; Sridharan, B; Viswanathan, P, 2016)
"Bergenin treatment significantly (P<0."1.43Bergenin attenuates renal injury by reversing mitochondrial dysfunction in ethylene glycol induced hyperoxaluric rat model. ( Aggarwal, D; Gautam, D; Sharma, M; Singla, SK, 2016)
"Bergenin was administrated at a dose of 10mg/kg body wt i."1.43Bergenin attenuates renal injury by reversing mitochondrial dysfunction in ethylene glycol induced hyperoxaluric rat model. ( Aggarwal, D; Gautam, D; Sharma, M; Singla, SK, 2016)
"Hyperoxaluria serves an important role in the pathophysiological process of stone formation."1.43Analysis of altered microRNA expression profiles in the kidney tissues of ethylene glycol-induced hyperoxaluric rats. ( Ding, Y; Jiang, H; Liu, J; Liu, Z; Wang, S; Wang, T; Yang, J; Ye, Z, 2016)
"Hyperoxaluria was induced successfully in rats."1.39Matrix Gla protein is involved in crystal formation in kidney of hyperoxaluric rats. ( Gao, B; Hirose, M; Kohri, K; Li, Y; Liu, T; Lu, X; Mao, X; Wu, Y; Xiao, C; Yasui, T; Yu, D; Zhu, Q, 2013)
"Treatment of ethylene glycol intoxication is based on specific inhibitors of alcohol dehydrogenase and hemodialysis in the most severe forms, and should be started promptly."1.39[Secondary hyperoxaluria and nephrocalcinosis due to ethylene glycol poisoning]. ( Harambat, J; Llanas, B; Missonnier, S; Monet, C; Rebouissoux, L; Richard, E, 2013)
"Calcium oxalate lithiasis was induced in rats by oral administration of 0."1.38Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012)
"Drawbacks of presently available treatments for urolithiasis necessitate finding the treatment of hyperoxaluria specifically aimed at reduction in oxalate excretion."1.38Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012)
"These effects of hyperoxaluria were reversed by concurrent PGG treatment along with decreased urinary oxalate levels and CaOx supersaturation."1.371,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model. ( Bae, H; Jeong, SJ; Kim, SH; Lee, EO; Lee, HJ; Lieske, JC, 2011)
"There is some evidence that hyperoxaluria may effect vascular endothelium and many studies link renal stones to atherosclerosis."1.36Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"In groups 1A, 1B and 1C hyperoxaluria was induced with ethylene glycol for 2 weeks."1.36Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"Hyperoxaluria induced a significantly dense staining pattern in renal tissue asymmetrical dimethylarginine vs controls (p = 0."1.36Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders. ( Aydin, H; Comunoğlu, N; Koyuncu, HH; Mutlu, N; Sarica, K; Yencilek, F, 2010)
"Hyperoxaluria is a major risk factor for recurrent urolithiasis and nephrocalcinosis."1.35Hyperoxaluria is reduced and nephrocalcinosis prevented with an oxalate-degrading enzyme in mice with hyperoxaluria. ( Grujic, D; Jung, CW; Langman, CB; Mandapati, S; Margolin, AL; McGrath, ME; Patel, RJ; Rashid, A; Salido, EC; Shenoy, BC, 2009)
"Hyperoxaluria was induced in male Wistar rats with 0."1.35Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008)
"This study explored whether vitamin E deficiency affects intrarenal oxidative stress and accelerates crystal deposition in hyperoxaluria."1.35Low-vitamin E diet exacerbates calcium oxalate crystal formation via enhanced oxidative stress in rat hyperoxaluric kidney. ( Chen, J; Huang, HS; Ma, MC, 2009)
"Hyperoxaluria induced a decrease in the activities of TCA cycle enzymes and respiratory complex enzymes."1.35Mitochondrial dysfunction in an animal model of hyperoxaluria: a prophylactic approach with fucoidan. ( Josephine, A; Preetha, SP; Rajesh, NG; Varalakshmi, P; Veena, CK, 2008)
"Hyperoxaluria was induced in two groups by the administration of 0."1.34Effect of sulphated polysaccharides on erythrocyte changes due to oxidative and nitrosative stress in experimental hyperoxaluria. ( Josephine, A; Preetha, SP; Varalakshmi, P; Veena, CK, 2007)
"Hyperoxaluria was induced using 0."1.33Counteraction of oxalate induced nitrosative stress by supplementation of l-arginine, a potent antilithic agent. ( Kalaiselvi, P; Pragasam, V; Srinivasan, S; Sumitra, K; Varalakshmi, P, 2005)
"Frank metabolic acidosis was observed in the MA rats: decreased arterial pH and plasma HCO3(-) concentration with lower urinary pH and citrate excretion with elevated excretion of ammonium, phosphate and, hence, titratable acid."1.33Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005)
"Hyperoxaluria was induced by 0."1.33Oral L-arginine supplementation ameliorates urinary risk factors and kinetic modulation of Tamm-Horsfall glycoprotein in experimental hyperoxaluric rats. ( Kalaiselvi, P; Pragasam, V; Srinivasan, S; Sumitra, K; Varalakshmi, P, 2005)
"Mild hyperoxaluria was induced in male Wistar rats using ethylene glycol (EG; 0."1.33Mild tubular damage induces calcium oxalate crystalluria in a model of subtle hyperoxaluria: Evidence that a second hit is necessary for renal lithogenesis. ( D'Angelo, A; Del Prete, D; Della Barbera, M; Gambaro, G; Trevisan, A; Valente, ML; Zanetti, E, 2006)
"Chronic hyperoxaluria was induced by adding 0."1.32Changes in renal hemodynamics and urodynamics in rats with chronic hyperoxaluria and after acute oxalate infusion: role of free radicals. ( Chen, CF; Chen, J; Huang, HS; Ma, MC, 2003)
"Hyperoxaluria was induced in male Wistar rats by feeding 0."1.32Expression of nuclear pore complex oxalate binding protein p62 in experimental hyperoxaluria. ( Kalaiselvi, P; Sakthivel, R; Selvam, R; Sivakamasundari, P; Varalakshmi, P, 2004)
"During hyperoxaluria osteopontin expression in the kidneys was increased but still mostly limited to cells of the thin limb and papillary surface epithelium."1.31Expression of osteopontin in rat kidneys: induction during ethylene glycol induced calcium oxalate nephrolithiasis. ( Cornelius, JG; Glenton, PA; Johnson, JM; Khan, SR; Peck, AB, 2002)
"Calcium oxalate nephrolithiasis was induced by administering ethylene glycol."1.31Expression of osteopontin in rat kidneys: induction during ethylene glycol induced calcium oxalate nephrolithiasis. ( Cornelius, JG; Glenton, PA; Johnson, JM; Khan, SR; Peck, AB, 2002)
"Hyperoxaluria was produced in male Wistar rats by adding ethylene glycol to their drinking water."1.31Possible biphasic changes of free radicals in ethylene glycol-induced nephrolithiasis in rats. ( Chen, CF; Chen, J; Chien, CT; Huang, HS, 2000)
"Hematuria was more prevalent than oxaluria (86% and 41%, respectively), but neither was individually predictive of acute renal failure."1.31Ethylene glycol toxicity: the role of serum glycolic acid in hemodialysis. ( Bush, BA; Dunnington, JE; Pappas, AA; Porter, WH; Rutter, PW, 2001)
"Hyperoxaluria was produced in rats by ethylene glycol in drinking water."1.30Lipid peroxidation in ethylene glycol induced hyperoxaluria and calcium oxalate nephrolithiasis. ( Hackett, RL; Khan, SR; Thamilselvan, S, 1997)
"At autopsy, progressed chronic renal oxalosis could be confirmed."1.30[Fatal chronic oxalosis after sublethal ethylene glycol poisoning]. ( Brachwitz, C; Lange, H; Nizze, H; Schwabbauer, P, 1997)
"Hyperoxaluria was induced by feeding ethylene glycol (EG) in drinking water."1.30Role of glutathione on renal mitochondrial status in hyperoxaluria. ( Muthukumar, A; Selvam, R, 1998)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (13.73)18.2507
2000's19 (37.25)29.6817
2010's19 (37.25)24.3611
2020's6 (11.76)2.80

Authors

AuthorsStudies
Wei, Z1
Cui, Y1
Tian, L1
Liu, Y3
Yu, Y1
Jin, X1
Li, H1
Wang, K1
Sun, Q1
Ahmad, Y1
Kissling, S1
Torrent, C1
Chiche, JD1
Liaudet, L1
Ltaief, Z1
He, Q1
Tang, Y1
Li, Y2
Wang, F1
Bao, J1
Gupta, S1
Abdelaziz, MA1
Ahmed, OM1
Abdel-Gabbar, M1
Mohammad, MR1
Ibrahim, SR1
Abdelzaher, MH1
Mohideen, AP1
Moawd, SA1
Geddawy, AI1
Zhu, W1
Duan, X1
Xiao, C2
Lan, Y1
Luo, L1
Wu, C1
Yang, Z1
Mai, X1
Lu, S1
Zhong, W1
Li, S1
He, Z1
Zhang, X1
Zeng, G1
Khan, A1
Bashir, S1
Khan, SR5
Convento, MB1
Pessoa, EA1
Cruz, E1
da Glória, MA1
Schor, N1
Borges, FT1
Sáenz-Medina, J1
Jorge, E1
Corbacho, C1
Santos, M1
Sánchez, A1
Soblechero, P1
Virumbrales, E1
Ramil, E1
Coronado, MJ1
Castillón, I1
Prieto, D1
Carballido, J1
Albert, A1
Tiwari, V1
Paul, E1
Ponnusamy, S1
Ganesan, D1
Prabhakaran, R1
Mariaraj Sivakumar, S1
Govindan Sadasivam, S1
Randhawa, R1
Bhardwaj, R1
Kaur, T1
Lu, X1
Gao, B1
Yasui, T1
Liu, T1
Mao, X1
Hirose, M1
Wu, Y1
Yu, D1
Zhu, Q1
Kohri, K1
Zhang, CY1
Kong, T1
Wu, WH1
Lan, MB1
Monet, C1
Richard, E1
Missonnier, S1
Rebouissoux, L1
Llanas, B1
Harambat, J1
Tsuji, H1
Wang, W1
Sunil, J1
Shimizu, N1
Yoshimura, K1
Uemura, H1
Peck, AB2
Breljak, D1
Brzica, H1
Vrhovac, I1
Micek, V1
Karaica, D1
Ljubojević, M1
Sekovanić, A1
Jurasović, J1
Rašić, D1
Peraica, M1
Lovrić, M1
Schnedler, N1
Henjakovic, M1
Wegner, W1
Burckhardt, G1
Burckhardt, BC1
Sabolić, I1
Sridharan, B1
Ganesh, RN1
Viswanathan, P1
Aggarwal, D1
Gautam, D1
Sharma, M1
Singla, SK1
Liu, Z1
Jiang, H1
Yang, J1
Wang, T1
Ding, Y1
Liu, J1
Wang, S1
Ye, Z1
Oksay, T1
Yunusoğlu, S1
Calapoğlu, M1
Aydın Candan, I1
Onaran, İ1
Ergün, O1
Özorak, A1
Stapenhorst, L1
Hesse, A1
Hoppe, B1
Grujic, D1
Salido, EC1
Shenoy, BC1
Langman, CB1
McGrath, ME1
Patel, RJ1
Rashid, A1
Mandapati, S1
Jung, CW1
Margolin, AL1
Sudhahar, V1
Veena, CK3
Varalakshmi, P6
Huang, HS3
Ma, MC2
Chen, J3
Aydin, H1
Yencilek, F1
Mutlu, N1
Comunoğlu, N1
Koyuncu, HH1
Sarica, K1
Divakar, K1
Pawar, AT1
Chandrasekhar, SB1
Dighe, SB1
Divakar, G1
Lee, HJ2
Jeong, SJ1
Lee, EO1
Bae, H1
Lieske, JC1
Kim, SH1
Pareta, SK1
Patra, KC1
Mazumder, PM1
Sasmal, D1
Amengual-Cladera, E1
Nadal-Casellas, A1
Gómez-Pérez, Y1
Gomila, I1
Prieto, RM1
Proenza, AM1
Lladó, I1
Gadge, NB2
Jalalpure, SS1
Johnson, JM1
Cornelius, JG1
Glenton, PA1
Chen, CF2
Sivakamasundari, P1
Sakthivel, R1
Kalaiselvi, P3
Selvam, R2
Pragasam, V2
Sumitra, K2
Srinivasan, S2
Yamaguchi, S1
Wiessner, JH1
Hasegawa, AT1
Hung, LY1
Mandel, GS1
Mandel, NS1
Green, ML1
Hatch, M1
Freel, RW1
Karadi, RV1
Alagawadi, KR1
Savadi, RV1
Gambaro, G1
Valente, ML1
Zanetti, E1
Della Barbera, M1
Del Prete, D1
D'Angelo, A1
Trevisan, A1
Gaines, L1
Waibel, KH1
Josephine, A2
Preetha, SP2
Rajesh, NG1
de Bruijn, WC3
Boevé, ER3
van Run, PR3
van Miert, PP3
Romijn, JC3
Verkoelen, CF3
Cao, LC3
Schröder, FH2
de Water, R2
van 't Noordende, JM1
Schrder, FH1
Thamilselvan, S2
Hackett, RL1
Nizze, H1
Schwabbauer, P1
Brachwitz, C1
Lange, H1
Muthukumar, A1
Chien, CT1
Porter, WH1
Rutter, PW1
Bush, BA1
Pappas, AA1
Dunnington, JE1
Bais, R1
Rofe, AM1
Conyers, RA1

Reviews

3 reviews available for ethylene glycol and Hyperoxaluria

ArticleYear
The three biological gaps and hyperoxaluria in ethylene glycol poisoning: case presentation and review.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:20

    Topics: Acidosis; Antidotes; Delayed Diagnosis; Ethylene Glycol; Female; Fomepizole; Humans; Hyperoxaluria;

2021
Antiurolithic effects of medicinal plants: results of in vivo studies in rat models of calcium oxalate nephrolithiasis-a systematic review.
    Urolithiasis, 2021, Volume: 49, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Calcium Oxalate; Crystallization; Disease Models, A

2021
Nephrolithiasis: a consequence of renal epithelial cell exposure to oxalate and calcium oxalate crystals.
    Molecular urology, 2000,Winter, Volume: 4, Issue:4

    Topics: Animals; Calcium Oxalate; Cell Aggregation; Cell Line; Crystallization; Dogs; Ethylene Glycol; Human

2000

Other Studies

48 other studies available for ethylene glycol and Hyperoxaluria

ArticleYear
Probiotic Lactiplantibacillus plantarum N-1 could prevent ethylene glycol-induced kidney stones by regulating gut microbiota and enhancing intestinal barrier function.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:11

    Topics: Animals; Colon; Ethylene Glycol; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Hyperoxa

2021
A pilot dynamic analysis of formative factors of nephrolithiasis related to metabolic syndrome: evidence in a rat model.
    Renal failure, 2022, Volume: 44, Issue:1

    Topics: Ammonium Chloride; Animals; Ethylene Glycol; Humans; Hyperoxaluria; Inflammation; Kidney Calculi; Ma

2022
The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:8

    Topics: Animals; Antioxidants; Atorvastatin; Body Weight; Creatinine; Ethylene Glycol; Humans; Hyperoxaluria

2023
Alteration of the gut microbiota by vinegar is associated with amelioration of hyperoxaluria-induced kidney injury.
    Food & function, 2020, Mar-01, Volume: 11, Issue:3

    Topics: Acetic Acid; Administration, Oral; Animals; Ethylene Glycol; Gastrointestinal Microbiome; Hyperoxalu

2020
Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury.
    Scientific reports, 2017, 04-07, Volume: 7

    Topics: Animals; Calcium Oxalate; Cell Movement; Epithelial-Mesenchymal Transition; Ethylene Glycol; Fibrosi

2017
Metabolic syndrome contributes to renal injury mediated by hyperoxaluria in a murine model of nephrolithiasis.
    Urolithiasis, 2018, Volume: 46, Issue:2

    Topics: Animals; Calcium Oxalate; Creatinine; Diet, Carbohydrate Loading; Disease Models, Animal; Ethylene G

2018
Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats.
    Toxicology mechanisms and methods, 2018, Volume: 28, Issue:3

    Topics: Administration, Oral; Animals; Biomarkers; Crystallization; Disease Models, Animal; Ethylene Glycol;

2018
Amelioration of hyperoxaluria-induced kidney dysfunction by chemical chaperone 4-phenylbutyric acid.
    Urolithiasis, 2019, Volume: 47, Issue:2

    Topics: Animals; Biomarkers; Calcium Oxalate; Disease Models, Animal; Drug Evaluation, Preclinical; Endoplas

2019
Matrix Gla protein is involved in crystal formation in kidney of hyperoxaluric rats.
    Kidney & blood pressure research, 2013, Volume: 37, Issue:1

    Topics: Animals; Calcium-Binding Proteins; Ethylene Glycol; Extracellular Matrix Proteins; Hyperoxaluria; Ki

2013
The protection of polysaccharide from the Brown Seaweed Sargassum graminifolium against ethylene glycol-induced mitochondrial damage.
    Marine drugs, 2013, Mar-13, Volume: 11, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Antioxidants; Dose-Response Relationship, Drug; Ethylene Glycol;

2013
[Secondary hyperoxaluria and nephrocalcinosis due to ethylene glycol poisoning].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2013, Volume: 20, Issue:8

    Topics: Accidents, Home; Acidosis; Calcium Oxalate; Child, Preschool; Citric Acid; Ethylene Glycol; Fluid Th

2013
Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury.
    World journal of urology, 2016, Volume: 34, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Angiotensinogen; Animals; Calcium Oxalate; Cell Line; C

2016
In female rats, ethylene glycol treatment elevates protein expression of hepatic and renal oxalate transporter sat-1 (Slc26a1) without inducing hyperoxaluria.
    Croatian medical journal, 2015, Volume: 56, Issue:5

    Topics: Alcohol Dehydrogenase; Animals; Anion Transport Proteins; Antiporters; Blotting, Western; Calcium Ox

2015
Polyacrylic acid attenuates ethylene glycol induced hyperoxaluric damage and prevents crystal aggregation in vitro and in vivo.
    Chemico-biological interactions, 2016, May-25, Volume: 252

    Topics: Acrylic Resins; Animals; Calcium Oxalate; Ethylene Glycol; Female; Hyperoxaluria; Kidney; Liver; Mal

2016
Bergenin attenuates renal injury by reversing mitochondrial dysfunction in ethylene glycol induced hyperoxaluric rat model.
    European journal of pharmacology, 2016, Nov-15, Volume: 791

    Topics: Animals; Antioxidants; Benzopyrans; Biomarkers; Chemokine CCL2; Creatinine; Cytoprotection; Disease

2016
Analysis of altered microRNA expression profiles in the kidney tissues of ethylene glycol-induced hyperoxaluric rats.
    Molecular medicine reports, 2016, Volume: 14, Issue:5

    Topics: Animals; Cluster Analysis; Computational Biology; Ethylene Glycol; Gene Expression Profiling; Gene E

2016
Protective impact of resveratrol in experimental rat model of hyperoxaluria.
    International urology and nephrology, 2017, Volume: 49, Issue:5

    Topics: Animals; Antioxidants; Biopsy, Needle; Disease Models, Animal; Ethylene Glycol; Hyperoxaluria; Immun

2017
Hyperoxaluria after ethylene glycol poisoning.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:12

    Topics: Child; Drug Overdose; Ethanol; Ethylene Glycol; Female; Humans; Hyperoxaluria; Renal Dialysis; Suici

2008
Hyperoxaluria is reduced and nephrocalcinosis prevented with an oxalate-degrading enzyme in mice with hyperoxaluria.
    American journal of nephrology, 2009, Volume: 29, Issue:2

    Topics: Administration, Oral; Amino Acid Transport Systems; Animals; Carboxy-Lyases; Chemistry, Pharmaceutic

2009
Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria.
    Journal of natural products, 2008, Volume: 71, Issue:9

    Topics: Administration, Oral; Animals; Disease Models, Animal; Ethylene Glycol; Hyperoxaluria; Kidney Calcul

2008
Low-vitamin E diet exacerbates calcium oxalate crystal formation via enhanced oxidative stress in rat hyperoxaluric kidney.
    American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:1

    Topics: Animals; Calcium Oxalate; Crystallization; Dietary Supplements; Disease Models, Animal; Ethylene Gly

2009
Ethylene glycol induced hyperoxaluria increases plasma and renal tissue asymmetrical dimethylarginine in rats: a new pathogenetic link in hyperoxaluria induced disorders.
    The Journal of urology, 2010, Volume: 183, Issue:2

    Topics: Animals; Arginine; Ethylene Glycol; Hyperoxaluria; Rats; Rats, Sprague-Dawley; Tissue Distribution;

2010
Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:4

    Topics: Animals; Antioxidants; Calcium; Disease Models, Animal; Ethanol; Ethylene Glycol; Hyperoxaluria; Kid

2010
1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model.
    Kidney international, 2011, Volume: 79, Issue:5

    Topics: Animals; Apoptosis; Crystallization; Ethylene Glycol; Hyaluronic Acid; Hydrolyzable Tannins; Hyperox

2011
Aqueous extract of Boerhaavia diffusa root ameliorates ethylene glycol-induced hyperoxaluric oxidative stress and renal injury in rat kidney.
    Pharmaceutical biology, 2011, Volume: 49, Issue:12

    Topics: Acute Kidney Injury; Animals; Antioxidants; Biphenyl Compounds; Catalase; Chromatography, Thin Layer

2011
Phytotherapy in a rat model of hyperoxaluria: the antioxidant effects of quercetin involve serum paraoxonase 1 activation.
    Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:10

    Topics: Animals; Antioxidants; Apolipoprotein A-I; Aryldialkylphosphatase; Blotting, Western; Catechin; Chol

2011
Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats.
    Pharmaceutical biology, 2012, Volume: 50, Issue:3

    Topics: Animals; Bombax; Calcium; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Female; Fruit; H

2012
Expression of osteopontin in rat kidneys: induction during ethylene glycol induced calcium oxalate nephrolithiasis.
    The Journal of urology, 2002, Volume: 168, Issue:3

    Topics: Animals; Blotting, Western; Calcium Oxalate; Electrophoresis, Polyacrylamide Gel; Ethylene Glycol; H

2002
Changes in renal hemodynamics and urodynamics in rats with chronic hyperoxaluria and after acute oxalate infusion: role of free radicals.
    Neurourology and urodynamics, 2003, Volume: 22, Issue:2

    Topics: Acute Disease; Animals; Chronic Disease; Ethylene Glycol; Free Radicals; Glomerular Filtration Rate;

2003
Expression of nuclear pore complex oxalate binding protein p62 in experimental hyperoxaluria.
    Nephron. Experimental nephrology, 2004, Volume: 97, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Carbon Radioisotopes; Cell Extracts; Chromatography, Gel; Ethylene

2004
Counteraction of oxalate induced nitrosative stress by supplementation of l-arginine, a potent antilithic agent.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 354, Issue:1-2

    Topics: Animals; Antioxidants; Arginine; Body Weight; Dietary Supplements; Disease Models, Animal; Ethylene

2005
Study of a rat model for calcium oxalate crystal formation without severe renal damage in selected conditions.
    International journal of urology : official journal of the Japanese Urological Association, 2005, Volume: 12, Issue:3

    Topics: Acetylglucosaminidase; Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models,

2005
Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats.
    American journal of physiology. Renal physiology, 2005, Volume: 289, Issue:3

    Topics: Acidosis; Animals; Carbon Dioxide; Disease Models, Animal; Electrolytes; Ethylene Glycol; Hyperoxalu

2005
Oral L-arginine supplementation ameliorates urinary risk factors and kinetic modulation of Tamm-Horsfall glycoprotein in experimental hyperoxaluric rats.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 360, Issue:1-2

    Topics: Animals; Arginine; Biomarkers; Calcium Compounds; Calcium Oxalate; Citric Acid; Clinical Enzyme Test

2005
Effect of Moringa oleifera Lam. root-wood on ethylene glycol induced urolithiasis in rats.
    Journal of ethnopharmacology, 2006, Apr-21, Volume: 105, Issue:1-2

    Topics: Animals; Ethylene Glycol; Female; Hyperoxaluria; Male; Moringa oleifera; Plant Roots; Rats; Rats, Wi

2006
Mild tubular damage induces calcium oxalate crystalluria in a model of subtle hyperoxaluria: Evidence that a second hit is necessary for renal lithogenesis.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:8

    Topics: Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Ethylene Glycol; Hyperoxaluria; K

2006
Calcium oxalate crystalluria.
    Emergency medicine journal : EMJ, 2007, Volume: 24, Issue:4

    Topics: Adult; Calcium Oxalate; Diagnosis, Differential; Ethanol; Ethylene Glycol; Humans; Hyperoxaluria; Ma

2007
Mitochondrial dysfunction in an animal model of hyperoxaluria: a prophylactic approach with fucoidan.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Animals; Antioxidants; Citric Acid Cycle; Disease Models, Animal; Ethylene Glycol; Fucus; Glutathion

2008
Effect of sulphated polysaccharides on erythrocyte changes due to oxidative and nitrosative stress in experimental hyperoxaluria.
    Human & experimental toxicology, 2007, Volume: 26, Issue:12

    Topics: Animals; Biomarkers; Carbon Radioisotopes; Disease Models, Animal; Erythrocytes; Ethylene Glycol; Fu

2007
Etiology of experimental calcium oxalate monohydrate nephrolithiasis in rats.
    Scanning microscopy, 1994, Volume: 8, Issue:3

    Topics: Ammonium Chloride; Animals; Calcium Oxalate; Diet; Ethylene Glycol; Ethylene Glycols; Hyperoxaluria;

1994
Etiology of calcium oxalate nephrolithiasis in rats. I. Can this be a model for human stone formation?
    Scanning microscopy, 1995, Volume: 9, Issue:1

    Topics: Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Ethylene Glyco

1995
Etiology of calcium oxalate nephrolithiasis in rats. II. The role of the papilla in stone formation.
    Scanning microscopy, 1995, Volume: 9, Issue:1

    Topics: Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Electron Probe

1995
Lipid peroxidation in ethylene glycol induced hyperoxaluria and calcium oxalate nephrolithiasis.
    The Journal of urology, 1997, Volume: 157, Issue:3

    Topics: Animals; Calcium Oxalate; Ethylene Glycol; Ethylene Glycols; Hyperoxaluria; Kidney Calculi; Lipid Pe

1997
[Fatal chronic oxalosis after sublethal ethylene glycol poisoning].
    Der Pathologe, 1997, Volume: 18, Issue:4

    Topics: Adult; Biopsy, Needle; Ethylene Glycol; Fatal Outcome; Humans; Hyperoxaluria; Hypertension, Renal; K

1997
Role of glutathione on renal mitochondrial status in hyperoxaluria.
    Molecular and cellular biochemistry, 1998, Volume: 185, Issue:1-2

    Topics: Albinism; Animals; Buthionine Sulfoximine; Ethylene Glycol; Glutathione; Hyperoxaluria; Kidney; Kidn

1998
Possible biphasic changes of free radicals in ethylene glycol-induced nephrolithiasis in rats.
    BJU international, 2000, Volume: 85, Issue:9

    Topics: Animals; Ethylene Glycol; Free Radicals; Hyperoxaluria; Kidney Calculi; Luminescent Measurements; Ma

2000
Ethylene glycol toxicity: the role of serum glycolic acid in hemodialysis.
    Journal of toxicology. Clinical toxicology, 2001, Volume: 39, Issue:6

    Topics: Bicarbonates; Biomarkers; Central Nervous System Diseases; Ethylene Glycol; Gas Chromatography-Mass

2001
The inhibition of metabolic oxalate production by sulfhydryl compounds.
    The Journal of urology, 1991, Volume: 145, Issue:6

    Topics: Aluminum; Animals; Carbon Dioxide; Cysteine; Ethylene Glycol; Ethylene Glycols; Hyperoxaluria; In Vi

1991