ethylene glycol has been researched along with Disease Models, Animal in 71 studies
Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Most of the studies used ethylene glycol (EG) to induce hyperoxaluria and nephrolithiasis in rats." | 9.12 | Antiurolithic effects of medicinal plants: results of in vivo studies in rat models of calcium oxalate nephrolithiasis-a systematic review. ( Bashir, S; Khan, A; Khan, SR, 2021) |
| " With this in mind, the present study was designed to assess the antiurolithic effect of olive oil in a mouse model of ethylene glycol (EG)-induced urolithiasis." | 7.85 | Antiurolithic effect of olive oil in a mouse model of ethylene glycol-induced urolithiasis. ( Alenzi, M; Rahiman, S; Tantry, BA, 2017) |
| " The present work investigated the effect of methanolic and aqueous extracts of leaves of Chenopodium album on experimentally-induced urolithiasis in rats to substantiate its traditional use as antilithiatic agent." | 7.85 | Chenopodium album Linn. leaves prevent ethylene glycol-induced urolithiasis in rats. ( Dey, YN; Gaidhani, SN; Jadhav, AD; Sharma, A; Sikarwar, I; Wanjari, MM, 2017) |
| " The rats were randomized into three groups: Group 1 consisted of the controls (n = 8), Group 2 of hyperoxaluria (1% ethylene glycol (EG), n = 8), and Group 3 of the treatment (1% EG + 10 mg/kg of RES, n = 8) group." | 7.85 | Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017) |
| "In the present study, resveratrol was seen to prevent hyperoxaluria." | 7.85 | Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017) |
| "Context There have not been any conclusive studies of the effects of diosmin, a modified flavanone glycoside obtained from Teucrium gnaphalodes L'Her (Lamiaceae), on urolithiasis." | 7.83 | Evaluation of protective effects of diosmin (a citrus flavonoid) in chemical-induced urolithiasis in experimental rats. ( Anuradha, M; Das, S; Pachiappan, S; Prabhu, VV; Ramasamy, A; Sathyamurthy, D, 2016) |
| "We showed that amlodipine may increase susceptibility to urolithiasis by raising hyperoxaluria and hypercalciuria." | 7.79 | The biochemical and histopathological investigation of amlodipine in ethylene glycol-induced urolithiasis rat model. ( Albayrak, A; Bayir, Y; Colak, S; Dorman, E; Gulcan, E; Halici, Z; Karakus, E; Keles, MS; Oral, A; Uludag, K; Yayla, N; Zipak, T, 2013) |
| "The effect of 5 mg/kg amlodipine was studied in rats that were first treated with 1% ethylene glycol and 1% ammonium chloride for 21 days to induce urolithiasis." | 7.79 | The biochemical and histopathological investigation of amlodipine in ethylene glycol-induced urolithiasis rat model. ( Albayrak, A; Bayir, Y; Colak, S; Dorman, E; Gulcan, E; Halici, Z; Karakus, E; Keles, MS; Oral, A; Uludag, K; Yayla, N; Zipak, T, 2013) |
| "Urinary calculi are a common and severe problem, which are formed by urolithiasis or by the formation of calcium oxalate (CaOx) crystals in the kidneys." | 7.79 | The biochemical and histopathological investigation of amlodipine in ethylene glycol-induced urolithiasis rat model. ( Albayrak, A; Bayir, Y; Colak, S; Dorman, E; Gulcan, E; Halici, Z; Karakus, E; Keles, MS; Oral, A; Uludag, K; Yayla, N; Zipak, T, 2013) |
| "To evaluate prophylactic potentials of total flavonoids, total phenolics and polysaccharides from OS on experimental induction of calcium oxalate (CaOx) nephrolithiasis in rats." | 7.78 | Prophylactic effects of Orthosiphon stamineus Benth. extracts on experimental induction of calcium oxalate nephrolithiasis in rats. ( Cai, HF; Wang, ZY; Ying, HZ; Yu, CH; Zhong, YS, 2012) |
| "Oral administration of ethylene glycol resulted in hyperoxaluria and increased renal excretion of calcium and phosphate." | 7.78 | Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012) |
| "Several animal species are used to study calcium oxalate urolithiasis; however, an ideal model has yet to be identified." | 7.77 | Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis. ( Chang, CH; Chen, HY; Chen, WC; Chen, YH; Lee, YJ; Lin, WY; Liu, HP; Tsai, FJ, 2011) |
| " (HARC) against ethylene glycol induced urolithiasis and its possible underlying mechanisms using male Wistar albino rats." | 7.76 | Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010) |
| "Results confirm that hyperoxaluria induction alone is not sufficient to create calcium oxalate nephrolithiasis in mice." | 7.76 | Experimental induction of calcium oxalate nephrolithiasis in mice. ( Glenton, PA; Khan, SR, 2010) |
| "Indicate that the HARC can protect against ethylene glycol induced urolithiasis as it reduced and prevented the growth of urinary stones." | 7.76 | Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010) |
| "The aim of this study was to investigate the effects of thymoquinone, a major component of Nigella Sativa seeds on ethylene glycol-induced kidney calculi in rats." | 7.74 | Effect of thymoquinone on ethylene glycol-induced kidney calculi in rats. ( Hadjzadeh, MA; Mohammadian, N; Rahmani, Z; Rassouli, FB, 2008) |
| "The present study was undertaken to explore the efficiency of the pentacyclic triterpene lupeol (1) and its ester derivative, lupeol linoleate (2), in experimental hyperoxaluria." | 7.74 | Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008) |
| "Ethylene glycol (EG) consumption is commonly employed as an experimental regimen to induce hyperoxaluria in animal models of calcium oxalate nephrolithiasis." | 7.73 | Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005) |
| "Hyperoxaluria is characterized by an increased excretion of urinary oxalate which is caused by inherited disorders or high oxalate intake leading to renal stone ailment." | 5.51 | Amelioration of hyperoxaluria-induced kidney dysfunction by chemical chaperone 4-phenylbutyric acid. ( Bhardwaj, R; Kaur, T; Randhawa, R, 2019) |
| "Urolithiasis was induced in rats by administration of 0." | 5.46 | Chenopodium album Linn. leaves prevent ethylene glycol-induced urolithiasis in rats. ( Dey, YN; Gaidhani, SN; Jadhav, AD; Sharma, A; Sikarwar, I; Wanjari, MM, 2017) |
| "In the hyperoxaluria group, urinary oxalate levels were higher than the control group; yet, lower in the treatment group compared to hyperoxaluria group (p < 0." | 5.46 | Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017) |
| "Drawbacks of presently available treatments for urolithiasis necessitate finding the treatment of hyperoxaluria specifically aimed at reduction in oxalate excretion." | 5.38 | Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012) |
| "Calcium oxalate lithiasis was induced in rats by oral administration of 0." | 5.38 | Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012) |
| "Calcium oxalate deposits were smaller in the experimental groups than the ethylene glycol group." | 5.35 | Effect of thymoquinone on ethylene glycol-induced kidney calculi in rats. ( Hadjzadeh, MA; Mohammadian, N; Rahmani, Z; Rassouli, FB, 2008) |
| "Hyperoxaluria was induced in male Wistar rats with 0." | 5.35 | Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008) |
| "Mild hyperoxaluria was induced in male Wistar rats using ethylene glycol (EG; 0." | 5.33 | Mild tubular damage induces calcium oxalate crystalluria in a model of subtle hyperoxaluria: Evidence that a second hit is necessary for renal lithogenesis. ( D'Angelo, A; Del Prete, D; Della Barbera, M; Gambaro, G; Trevisan, A; Valente, ML; Zanetti, E, 2006) |
| "Frank metabolic acidosis was observed in the MA rats: decreased arterial pH and plasma HCO3(-) concentration with lower urinary pH and citrate excretion with elevated excretion of ammonium, phosphate and, hence, titratable acid." | 5.33 | Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005) |
| " Most of the studies used ethylene glycol (EG) to induce hyperoxaluria and nephrolithiasis in rats." | 5.12 | Antiurolithic effects of medicinal plants: results of in vivo studies in rat models of calcium oxalate nephrolithiasis-a systematic review. ( Bashir, S; Khan, A; Khan, SR, 2021) |
| "Age, APACHE score at ICU admission, neurological disease, sepsis and duration of mechanical ventilation were all independent risk factors for the development of delirium in ICU patients." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "A high-salt diet increased crystal deposition in Dahl salt-sensitive rats with hypertension, and eplerenone administration significantly suppressed it." | 3.91 | High-salt diet promotes crystal deposition through hypertension in Dahl salt-sensitive rat model. ( Iida, Y; Inoue, S; Ishigaki, Y; Miyazawa, K; Nakamura, Y; Nakazawa, Y, 2019) |
| "Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural system." | 3.88 | Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats. ( Albert, A; Ganesan, D; Govindan Sadasivam, S; Mariaraj Sivakumar, S; Paul, E; Ponnusamy, S; Prabhakaran, R; Tiwari, V, 2018) |
| "In the present study, resveratrol was seen to prevent hyperoxaluria." | 3.85 | Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017) |
| " With this in mind, the present study was designed to assess the antiurolithic effect of olive oil in a mouse model of ethylene glycol (EG)-induced urolithiasis." | 3.85 | Antiurolithic effect of olive oil in a mouse model of ethylene glycol-induced urolithiasis. ( Alenzi, M; Rahiman, S; Tantry, BA, 2017) |
| " The rats were randomized into three groups: Group 1 consisted of the controls (n = 8), Group 2 of hyperoxaluria (1% ethylene glycol (EG), n = 8), and Group 3 of the treatment (1% EG + 10 mg/kg of RES, n = 8) group." | 3.85 | Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017) |
| " The present work investigated the effect of methanolic and aqueous extracts of leaves of Chenopodium album on experimentally-induced urolithiasis in rats to substantiate its traditional use as antilithiatic agent." | 3.85 | Chenopodium album Linn. leaves prevent ethylene glycol-induced urolithiasis in rats. ( Dey, YN; Gaidhani, SN; Jadhav, AD; Sharma, A; Sikarwar, I; Wanjari, MM, 2017) |
| "Context There have not been any conclusive studies of the effects of diosmin, a modified flavanone glycoside obtained from Teucrium gnaphalodes L'Her (Lamiaceae), on urolithiasis." | 3.83 | Evaluation of protective effects of diosmin (a citrus flavonoid) in chemical-induced urolithiasis in experimental rats. ( Anuradha, M; Das, S; Pachiappan, S; Prabhu, VV; Ramasamy, A; Sathyamurthy, D, 2016) |
| "Hyperoxaluria was induced in male SD rats by administering ethylene glycol." | 3.83 | Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016) |
| "Ob/Ob mice with Leptin gene deficiencies and metabolic syndrome related characteristics were compared with wild heterozygous lean mice." | 3.81 | Proinflammatory and Metabolic Changes Facilitate Renal Crystal Deposition in an Obese Mouse Model of Metabolic Syndrome. ( Ando, R; Hamamoto, S; Iwatsuki, S; Kohri, K; Mizuno, K; Naiki, T; Okada, A; Taguchi, K; Tozawa, K; Yasui, T, 2015) |
| "We induced renal crystal deposition in mice with metabolic syndrome using a high fat diet and ethylene glycol." | 3.81 | Proinflammatory and Metabolic Changes Facilitate Renal Crystal Deposition in an Obese Mouse Model of Metabolic Syndrome. ( Ando, R; Hamamoto, S; Iwatsuki, S; Kohri, K; Mizuno, K; Naiki, T; Okada, A; Taguchi, K; Tozawa, K; Yasui, T, 2015) |
| "To clarify metabolic syndrome induced stone formation mechanisms we investigated the metabolic and immunohistochemical characteristics associated with renal crystal deposition using a model of mice with metabolic syndrome administered a high fat diet and ethylene glycol." | 3.81 | Proinflammatory and Metabolic Changes Facilitate Renal Crystal Deposition in an Obese Mouse Model of Metabolic Syndrome. ( Ando, R; Hamamoto, S; Iwatsuki, S; Kohri, K; Mizuno, K; Naiki, T; Okada, A; Taguchi, K; Tozawa, K; Yasui, T, 2015) |
| " Metabolic correction of these changes was successful in nephroprotection effectively normalizing kidney functions and the total protein concentration, eliminating hyperglycemia and reducing creatinine and urea blood plasma concentration in both rat experimental models." | 3.81 | [Metabolic therapy of nephrolithiasis in two different rat models of kidney disease]. ( Kovalenko, AL; Tagirov, NS; Trashkov, AP; Vasiliev, AG, 2015) |
| " (saffron), was evaluated against ethylene glycol (EG)-induced nephrolithiasis in rats." | 3.80 | Antilithiatic effects of crocin on ethylene glycol-induced lithiasis in rats. ( Amin, B; Ghaeni, FA; Hariri, AT; Hosseinzadeh, H; Meybodi, NT, 2014) |
| "We showed that amlodipine may increase susceptibility to urolithiasis by raising hyperoxaluria and hypercalciuria." | 3.79 | The biochemical and histopathological investigation of amlodipine in ethylene glycol-induced urolithiasis rat model. ( Albayrak, A; Bayir, Y; Colak, S; Dorman, E; Gulcan, E; Halici, Z; Karakus, E; Keles, MS; Oral, A; Uludag, K; Yayla, N; Zipak, T, 2013) |
| "The effect of 5 mg/kg amlodipine was studied in rats that were first treated with 1% ethylene glycol and 1% ammonium chloride for 21 days to induce urolithiasis." | 3.79 | The biochemical and histopathological investigation of amlodipine in ethylene glycol-induced urolithiasis rat model. ( Albayrak, A; Bayir, Y; Colak, S; Dorman, E; Gulcan, E; Halici, Z; Karakus, E; Keles, MS; Oral, A; Uludag, K; Yayla, N; Zipak, T, 2013) |
| "Urinary calculi are a common and severe problem, which are formed by urolithiasis or by the formation of calcium oxalate (CaOx) crystals in the kidneys." | 3.79 | The biochemical and histopathological investigation of amlodipine in ethylene glycol-induced urolithiasis rat model. ( Albayrak, A; Bayir, Y; Colak, S; Dorman, E; Gulcan, E; Halici, Z; Karakus, E; Keles, MS; Oral, A; Uludag, K; Yayla, N; Zipak, T, 2013) |
| "To evaluate prophylactic potentials of total flavonoids, total phenolics and polysaccharides from OS on experimental induction of calcium oxalate (CaOx) nephrolithiasis in rats." | 3.78 | Prophylactic effects of Orthosiphon stamineus Benth. extracts on experimental induction of calcium oxalate nephrolithiasis in rats. ( Cai, HF; Wang, ZY; Ying, HZ; Yu, CH; Zhong, YS, 2012) |
| "Oral administration of ethylene glycol resulted in hyperoxaluria and increased renal excretion of calcium and phosphate." | 3.78 | Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012) |
| "Several animal species are used to study calcium oxalate urolithiasis; however, an ideal model has yet to be identified." | 3.77 | Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis. ( Chang, CH; Chen, HY; Chen, WC; Chen, YH; Lee, YJ; Lin, WY; Liu, HP; Tsai, FJ, 2011) |
| "Results confirm that hyperoxaluria induction alone is not sufficient to create calcium oxalate nephrolithiasis in mice." | 3.76 | Experimental induction of calcium oxalate nephrolithiasis in mice. ( Glenton, PA; Khan, SR, 2010) |
| "Ethylene glycol (EG) exposure is a common model for kidney stones, because animals accumulate calcium oxalate monohydrate (COM) in kidneys." | 3.76 | Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity. ( Li, Y; McLaren, MC; McMartin, KE, 2010) |
| " (HARC) against ethylene glycol induced urolithiasis and its possible underlying mechanisms using male Wistar albino rats." | 3.76 | Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010) |
| "Indicate that the HARC can protect against ethylene glycol induced urolithiasis as it reduced and prevented the growth of urinary stones." | 3.76 | Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats. ( Chandrasekhar, SB; Dighe, SB; Divakar, G; Divakar, K; Pawar, AT, 2010) |
| "The present study was undertaken to explore the efficiency of the pentacyclic triterpene lupeol (1) and its ester derivative, lupeol linoleate (2), in experimental hyperoxaluria." | 3.74 | Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008) |
| "The aim of this study was to investigate the effects of thymoquinone, a major component of Nigella Sativa seeds on ethylene glycol-induced kidney calculi in rats." | 3.74 | Effect of thymoquinone on ethylene glycol-induced kidney calculi in rats. ( Hadjzadeh, MA; Mohammadian, N; Rahmani, Z; Rassouli, FB, 2008) |
| "Ethylene glycol (EG) consumption is commonly employed as an experimental regimen to induce hyperoxaluria in animal models of calcium oxalate nephrolithiasis." | 3.73 | Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005) |
| "Hyperoxaluria is characterized by an increased excretion of urinary oxalate which is caused by inherited disorders or high oxalate intake leading to renal stone ailment." | 1.51 | Amelioration of hyperoxaluria-induced kidney dysfunction by chemical chaperone 4-phenylbutyric acid. ( Bhardwaj, R; Kaur, T; Randhawa, R, 2019) |
| "Hypertension was induced by a high-salt diet." | 1.51 | High-salt diet promotes crystal deposition through hypertension in Dahl salt-sensitive rat model. ( Iida, Y; Inoue, S; Ishigaki, Y; Miyazawa, K; Nakamura, Y; Nakazawa, Y, 2019) |
| "Induction of hyperoxaluria in rats with MS causes severe morphological alterations with a significant impairment of renal function." | 1.48 | Metabolic syndrome contributes to renal injury mediated by hyperoxaluria in a murine model of nephrolithiasis. ( Carballido, J; Castillón, I; Corbacho, C; Coronado, MJ; Jorge, E; Prieto, D; Ramil, E; Sáenz-Medina, J; Sánchez, A; Santos, M; Soblechero, P; Virumbrales, E, 2018) |
| "Hypercalciuria is a main risk factor for kidney stone formation." | 1.48 | SaRNA-mediated activation of TRPV5 reduces renal calcium oxalate deposition in rat via decreasing urinary calcium excretion. ( Duan, X; Liu, Y; Wu, W; Zeng, G; Zeng, T; Zhu, W, 2018) |
| "Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural system." | 1.48 | Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats. ( Albert, A; Ganesan, D; Govindan Sadasivam, S; Mariaraj Sivakumar, S; Paul, E; Ponnusamy, S; Prabhakaran, R; Tiwari, V, 2018) |
| "Urolithiasis was induced in rats by administration of 0." | 1.46 | Chenopodium album Linn. leaves prevent ethylene glycol-induced urolithiasis in rats. ( Dey, YN; Gaidhani, SN; Jadhav, AD; Sharma, A; Sikarwar, I; Wanjari, MM, 2017) |
| "In the hyperoxaluria group, urinary oxalate levels were higher than the control group; yet, lower in the treatment group compared to hyperoxaluria group (p < 0." | 1.46 | Protective impact of resveratrol in experimental rat model of hyperoxaluria. ( Aydın Candan, I; Calapoğlu, M; Ergün, O; Oksay, T; Onaran, İ; Özorak, A; Yunusoğlu, S, 2017) |
| "Bergenin was administrated at a dose of 10mg/kg body wt i." | 1.43 | Bergenin attenuates renal injury by reversing mitochondrial dysfunction in ethylene glycol induced hyperoxaluric rat model. ( Aggarwal, D; Gautam, D; Sharma, M; Singla, SK, 2016) |
| "Bergenin treatment significantly (P<0." | 1.43 | Bergenin attenuates renal injury by reversing mitochondrial dysfunction in ethylene glycol induced hyperoxaluric rat model. ( Aggarwal, D; Gautam, D; Sharma, M; Singla, SK, 2016) |
| "Results indicate that hyperoxaluria-induced production of ROS, injury and inflammation are in part associated with the activation of Nox through renin-angiotensin-aldosterone pathway." | 1.43 | Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016) |
| "Hyperoxaluria was induced in male SD rats by administering ethylene glycol." | 1.43 | Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016) |
| "Treatment with spironolactone reversed the effect of hyperoxaluria." | 1.43 | Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury. ( Khan, SR; Peck, AB; Shimizu, N; Sunil, J; Tsuji, H; Uemura, H; Wang, W; Yoshimura, K, 2016) |
| "Treatment with crocin (20 and 40 mg/kg) reduced the elevated levels of MDA." | 1.40 | Antilithiatic effects of crocin on ethylene glycol-induced lithiasis in rats. ( Amin, B; Ghaeni, FA; Hariri, AT; Hosseinzadeh, H; Meybodi, NT, 2014) |
| "Ethylene glycol (0." | 1.40 | Prophylactic effects of quercetin and hyperoside in a calcium oxalate stone forming rat model. ( Che, JP; Feng, Y; Liu, M; Peng, B; Xu, YF; Zheng, JH; Zhu, W, 2014) |
| "Calcium oxalate lithiasis was induced in rats by oral administration of 0." | 1.38 | Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012) |
| "Drawbacks of presently available treatments for urolithiasis necessitate finding the treatment of hyperoxaluria specifically aimed at reduction in oxalate excretion." | 1.38 | Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats. ( Gadge, NB; Jalalpure, SS, 2012) |
| "Ethylene glycol (EG) exposure is a common model for kidney stones, because animals accumulate calcium oxalate monohydrate (COM) in kidneys." | 1.36 | Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity. ( Li, Y; McLaren, MC; McMartin, KE, 2010) |
| "Hyperoxaluria was induced in male Wistar rats with 0." | 1.35 | Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria. ( Sudhahar, V; Varalakshmi, P; Veena, CK, 2008) |
| "Hyperoxaluria is a major risk factor for recurrent urolithiasis and nephrocalcinosis." | 1.35 | Hyperoxaluria is reduced and nephrocalcinosis prevented with an oxalate-degrading enzyme in mice with hyperoxaluria. ( Grujic, D; Jung, CW; Langman, CB; Mandapati, S; Margolin, AL; McGrath, ME; Patel, RJ; Rashid, A; Salido, EC; Shenoy, BC, 2009) |
| "Calcium oxalate deposits were smaller in the experimental groups than the ethylene glycol group." | 1.35 | Effect of thymoquinone on ethylene glycol-induced kidney calculi in rats. ( Hadjzadeh, MA; Mohammadian, N; Rahmani, Z; Rassouli, FB, 2008) |
| "This study explored whether vitamin E deficiency affects intrarenal oxidative stress and accelerates crystal deposition in hyperoxaluria." | 1.35 | Low-vitamin E diet exacerbates calcium oxalate crystal formation via enhanced oxidative stress in rat hyperoxaluric kidney. ( Chen, J; Huang, HS; Ma, MC, 2009) |
| "Ethylene glycol (EG) was used in the experiment to induce calcium oxalate (CaOx) deposition into kidneys." | 1.35 | Cynodon dactylon extract as a preventive and curative agent in experimentally induced nephrolithiasis. ( Atmani, F; Aziz, M; Hacht, B; Mimouni, M; Sadki, C, 2009) |
| "Hyperoxaluria induced a decrease in the activities of TCA cycle enzymes and respiratory complex enzymes." | 1.35 | Mitochondrial dysfunction in an animal model of hyperoxaluria: a prophylactic approach with fucoidan. ( Josephine, A; Preetha, SP; Rajesh, NG; Varalakshmi, P; Veena, CK, 2008) |
| "Hyperoxaluria was induced in two groups by the administration of 0." | 1.34 | Effect of sulphated polysaccharides on erythrocyte changes due to oxidative and nitrosative stress in experimental hyperoxaluria. ( Josephine, A; Preetha, SP; Varalakshmi, P; Veena, CK, 2007) |
| "Hyperoxaluria was induced using 0." | 1.33 | Counteraction of oxalate induced nitrosative stress by supplementation of l-arginine, a potent antilithic agent. ( Kalaiselvi, P; Pragasam, V; Srinivasan, S; Sumitra, K; Varalakshmi, P, 2005) |
| "Frank metabolic acidosis was observed in the MA rats: decreased arterial pH and plasma HCO3(-) concentration with lower urinary pH and citrate excretion with elevated excretion of ammonium, phosphate and, hence, titratable acid." | 1.33 | Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats. ( Freel, RW; Green, ML; Hatch, M, 2005) |
| "Mild hyperoxaluria was induced in male Wistar rats using ethylene glycol (EG; 0." | 1.33 | Mild tubular damage induces calcium oxalate crystalluria in a model of subtle hyperoxaluria: Evidence that a second hit is necessary for renal lithogenesis. ( D'Angelo, A; Del Prete, D; Della Barbera, M; Gambaro, G; Trevisan, A; Valente, ML; Zanetti, E, 2006) |
| "In a rat model for nephrolithiasis, we investigated whether such crystals can be removed by the surrounding interstitial cells." | 1.31 | Role of macrophages in nephrolithiasis in rats: an analysis of the renal interstitium. ( de Water, R; Houtsmuller, AB; Kok, DJ; Nigg, AL; Noordermeer, C; Schröder, FH; Stijnen, T, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (9.86) | 18.2507 |
| 2000's | 19 (26.76) | 29.6817 |
| 2010's | 39 (54.93) | 24.3611 |
| 2020's | 6 (8.45) | 2.80 |
| Authors | Studies |
|---|---|
| Safari, HR | 1 |
| Esmaeili, S | 1 |
| Naghizadeh, MS | 1 |
| Falahpour, M | 1 |
| Malekaneh, M | 1 |
| Anani Sarab, GR | 1 |
| Cao, Y | 1 |
| Duan, B | 1 |
| Gao, X | 1 |
| Wang, E | 1 |
| Dong, Z | 2 |
| Karabulut, D | 1 |
| Kaymak, E | 1 |
| Yalçin, B | 1 |
| Ulger, H | 1 |
| Keti, DB | 1 |
| Khan, A | 1 |
| Bashir, S | 1 |
| Khan, SR | 3 |
| Marhoume, FZ | 1 |
| Aboufatima, R | 1 |
| Zaid, Y | 1 |
| Limami, Y | 1 |
| Duval, RE | 1 |
| Laadraoui, J | 1 |
| Belbachir, A | 1 |
| Chait, A | 1 |
| Bagri, A | 1 |
| Lan, Y | 1 |
| Zhu, W | 3 |
| Duan, X | 2 |
| Deng, T | 1 |
| Li, S | 1 |
| Liu, Y | 2 |
| Yang, Z | 1 |
| Wen, Y | 1 |
| Luo, L | 1 |
| Zhao, S | 1 |
| Wang, J | 1 |
| Zhao, Z | 1 |
| Wu, W | 2 |
| Zeng, G | 2 |
| Sáenz-Medina, J | 1 |
| Jorge, E | 1 |
| Corbacho, C | 1 |
| Santos, M | 1 |
| Sánchez, A | 1 |
| Soblechero, P | 1 |
| Virumbrales, E | 1 |
| Ramil, E | 1 |
| Coronado, MJ | 1 |
| Castillón, I | 1 |
| Prieto, D | 1 |
| Carballido, J | 1 |
| Alenzi, M | 1 |
| Rahiman, S | 1 |
| Tantry, BA | 1 |
| Yasir, F | 1 |
| Wahab, AT | 1 |
| Choudhary, MI | 1 |
| Pavlyashik, GV | 1 |
| Zharikov, AY | 1 |
| Kiselev, VI | 1 |
| Youn, SH | 1 |
| Kwon, JH | 1 |
| Yin, J | 1 |
| Tam, LT | 1 |
| Ahn, HS | 1 |
| Myung, SC | 1 |
| Lee, MW | 1 |
| Trojan, BP | 1 |
| Trojan, SJ | 1 |
| Navetta, A | 1 |
| Staches, B | 1 |
| Sutton, B | 1 |
| Filleur, S | 1 |
| Nelius, T | 1 |
| Zeng, T | 1 |
| Albert, A | 1 |
| Tiwari, V | 1 |
| Paul, E | 1 |
| Ponnusamy, S | 1 |
| Ganesan, D | 1 |
| Prabhakaran, R | 1 |
| Mariaraj Sivakumar, S | 1 |
| Govindan Sadasivam, S | 1 |
| Yousefi Ghale-Salimi, M | 1 |
| Eidi, M | 1 |
| Ghaemi, N | 1 |
| Khavari-Nejad, RA | 1 |
| Randhawa, R | 1 |
| Bhardwaj, R | 1 |
| Kaur, T | 1 |
| Guo, Y | 1 |
| Wang, T | 1 |
| Qiu, H | 1 |
| Han, M | 1 |
| Wang, X | 2 |
| Wang, Y | 1 |
| Yang, X | 2 |
| Yang, T | 2 |
| Li, J | 2 |
| Yang, R | 1 |
| Qi, S | 2 |
| Zhao, Y | 1 |
| Li, L | 1 |
| Zhang, X | 1 |
| Yang, K | 2 |
| Xu, Y | 2 |
| Liu, C | 2 |
| Nakazawa, Y | 1 |
| Inoue, S | 1 |
| Nakamura, Y | 1 |
| Iida, Y | 1 |
| Ishigaki, Y | 1 |
| Miyazawa, K | 1 |
| Xu, YF | 1 |
| Feng, Y | 1 |
| Peng, B | 1 |
| Che, JP | 1 |
| Liu, M | 1 |
| Zheng, JH | 1 |
| Ghaeni, FA | 1 |
| Amin, B | 1 |
| Hariri, AT | 1 |
| Meybodi, NT | 1 |
| Hosseinzadeh, H | 1 |
| Tsuji, H | 1 |
| Wang, W | 1 |
| Sunil, J | 1 |
| Shimizu, N | 1 |
| Yoshimura, K | 1 |
| Uemura, H | 1 |
| Peck, AB | 1 |
| Trashkov, AP | 1 |
| Vasiliev, AG | 1 |
| Kovalenko, AL | 1 |
| Tagirov, NS | 1 |
| Taguchi, K | 1 |
| Okada, A | 1 |
| Hamamoto, S | 1 |
| Iwatsuki, S | 1 |
| Naiki, T | 1 |
| Ando, R | 1 |
| Mizuno, K | 1 |
| Tozawa, K | 2 |
| Kohri, K | 5 |
| Yasui, T | 4 |
| Prabhu, VV | 1 |
| Sathyamurthy, D | 1 |
| Ramasamy, A | 1 |
| Das, S | 1 |
| Anuradha, M | 1 |
| Pachiappan, S | 1 |
| Yuruk, E | 1 |
| Tuken, M | 1 |
| Sahin, C | 1 |
| Kaptanagasi, AO | 1 |
| Basak, K | 1 |
| Aykan, S | 1 |
| Muslumanoglu, AY | 1 |
| Sarica, K | 2 |
| Aggarwal, D | 1 |
| Gautam, D | 1 |
| Sharma, M | 1 |
| Singla, SK | 2 |
| Sener, TE | 1 |
| Sener, G | 1 |
| Cevik, O | 1 |
| Eker, P | 1 |
| Cetinel, S | 1 |
| Traxer, O | 1 |
| Tanidir, Y | 1 |
| Akbal, C | 1 |
| Ding, H | 1 |
| Qin, Z | 1 |
| Zhang, C | 1 |
| Zhang, H | 1 |
| He, Z | 1 |
| Du, E | 1 |
| Zhang, Z | 2 |
| Sikarwar, I | 1 |
| Dey, YN | 1 |
| Wanjari, MM | 1 |
| Sharma, A | 1 |
| Gaidhani, SN | 1 |
| Jadhav, AD | 1 |
| Oksay, T | 1 |
| Yunusoğlu, S | 1 |
| Calapoğlu, M | 1 |
| Aydın Candan, I | 1 |
| Onaran, İ | 1 |
| Ergün, O | 1 |
| Özorak, A | 1 |
| Chen, WC | 2 |
| Chen, HY | 2 |
| Liao, PC | 1 |
| Wang, SJ | 1 |
| Tsai, MY | 1 |
| Chen, YH | 2 |
| Lin, WY | 2 |
| Grujic, D | 1 |
| Salido, EC | 2 |
| Shenoy, BC | 1 |
| Langman, CB | 1 |
| McGrath, ME | 1 |
| Patel, RJ | 1 |
| Rashid, A | 1 |
| Mandapati, S | 1 |
| Jung, CW | 1 |
| Margolin, AL | 1 |
| Sudhahar, V | 1 |
| Veena, CK | 3 |
| Varalakshmi, P | 4 |
| Huang, HS | 1 |
| Ma, MC | 1 |
| Chen, J | 1 |
| Hadjzadeh, MA | 1 |
| Mohammadian, N | 1 |
| Rahmani, Z | 1 |
| Rassouli, FB | 1 |
| Atmani, F | 1 |
| Sadki, C | 1 |
| Aziz, M | 1 |
| Mimouni, M | 1 |
| Hacht, B | 1 |
| Li, Y | 2 |
| McMartin, KE | 2 |
| Divakar, K | 1 |
| Pawar, AT | 1 |
| Chandrasekhar, SB | 1 |
| Dighe, SB | 1 |
| Divakar, G | 1 |
| McLaren, MC | 1 |
| Glenton, PA | 1 |
| Salido, E | 1 |
| Rodriguez-Pena, M | 1 |
| Santana, A | 1 |
| Beattie, SG | 1 |
| Petry, H | 1 |
| Torres, A | 1 |
| Geetha, K | 1 |
| Manavalan, R | 1 |
| Venkappayya, D | 1 |
| Liu, HP | 1 |
| Tsai, FJ | 1 |
| Chang, CH | 1 |
| Lee, YJ | 1 |
| Amengual-Cladera, E | 1 |
| Nadal-Casellas, A | 1 |
| Gómez-Pérez, Y | 1 |
| Gomila, I | 1 |
| Prieto, RM | 1 |
| Proenza, AM | 1 |
| Lladó, I | 1 |
| Gadge, NB | 1 |
| Jalalpure, SS | 1 |
| Aggarwal, A | 1 |
| Gandhi, M | 1 |
| Tandon, C | 1 |
| Patel, PK | 1 |
| Patel, MA | 1 |
| Vyas, BA | 1 |
| Shah, DR | 1 |
| Gandhi, TR | 1 |
| Zhong, YS | 1 |
| Yu, CH | 1 |
| Ying, HZ | 1 |
| Wang, ZY | 1 |
| Cai, HF | 1 |
| Albayrak, A | 1 |
| Bayir, Y | 1 |
| Halici, Z | 1 |
| Karakus, E | 1 |
| Oral, A | 1 |
| Keles, MS | 1 |
| Colak, S | 1 |
| Zipak, T | 1 |
| Dorman, E | 1 |
| Uludag, K | 1 |
| Yayla, N | 1 |
| Gulcan, E | 1 |
| Pragasam, V | 1 |
| Kalaiselvi, P | 1 |
| Sumitra, K | 1 |
| Srinivasan, S | 1 |
| Yamaguchi, S | 1 |
| Wiessner, JH | 1 |
| Hasegawa, AT | 1 |
| Hung, LY | 1 |
| Mandel, GS | 1 |
| Mandel, NS | 1 |
| Green, ML | 1 |
| Hatch, M | 1 |
| Freel, RW | 1 |
| Mohanasundari, M | 1 |
| Sabesan, M | 1 |
| Sethupathy, S | 1 |
| Bailer, AJ | 1 |
| Noble, RB | 1 |
| Wheeler, MW | 1 |
| Gambaro, G | 1 |
| Valente, ML | 1 |
| Zanetti, E | 1 |
| Della Barbera, M | 1 |
| Del Prete, D | 1 |
| D'Angelo, A | 1 |
| Trevisan, A | 1 |
| Liu, J | 1 |
| Cao, Z | 1 |
| Zhou, S | 1 |
| Ye, Z | 1 |
| Josephine, A | 2 |
| Preetha, SP | 2 |
| Rajesh, NG | 1 |
| Hack, JB | 1 |
| Early, J | 1 |
| Brewer, KL | 1 |
| Jiang, J | 1 |
| Guha, C | 1 |
| Moitra, R | 1 |
| Liu, L | 1 |
| Roy-Chowdhury, J | 1 |
| Roy-Chowdhury, N | 1 |
| de Bruijn, WC | 2 |
| Boevé, ER | 2 |
| van Run, PR | 2 |
| van Miert, PP | 2 |
| de Water, R | 3 |
| Romijn, JC | 2 |
| Verkoelen, CF | 2 |
| Cao, LC | 2 |
| Schröder, FH | 2 |
| van 't Noordende, JM | 1 |
| Schrder, FH | 1 |
| Soygür, T | 1 |
| Yaman, O | 1 |
| Ozer, G | 1 |
| Sayin, N | 1 |
| Akbay, C | 1 |
| Küpeli, S | 1 |
| Yaman, LS | 1 |
| Angayarkanni, N | 1 |
| Selvam, R | 1 |
| Fujita, K | 3 |
| Sato, M | 3 |
| Sugimoto, M | 2 |
| Iguchi, M | 2 |
| Nomura, S | 3 |
| Takamura, C | 1 |
| Umekawa, T | 1 |
| Kurita, T | 1 |
| Sasaki, S | 1 |
| Hirota, S | 1 |
| Kitamura, Y | 1 |
| Noordermeer, C | 1 |
| Houtsmuller, AB | 1 |
| Nigg, AL | 1 |
| Stijnen, T | 1 |
| Kok, DJ | 1 |
2 reviews available for ethylene glycol and Disease Models, Animal
1 trial available for ethylene glycol and Disease Models, Animal
69 other studies available for ethylene glycol and Disease Models, Animal
| Article | Year |
|---|---|
The Effects of Aqueous Extract of Eryngium Campestre on Ethylene Glycol-Induced Calcium Oxalate Kidney Stone in Rats.
Topics: Animals; Biomarkers; Calcium Oxalate; Cytokines; Disease Models, Animal; Dose-Response Relationship, | 2019 |
iTRAQ-Based Comparative Proteomics Analysis of Urolithiasis Rats Induced by Ethylene Glycol.
Topics: Animals; Disease Models, Animal; Ethylene Glycol; Kidney; Male; Protein Interaction Maps; Proteome; | 2020 |
A different perspective on the filtration barrier after kidney stone formation: An immunohistochemical and biochemical study.
Topics: Ammonium Chloride; Animals; Apoptosis; Disease Models, Animal; Ethylene Glycol; Glomerular Basement | 2021 |
Antioxidant and Polyphenol-Rich Ethanolic Extract of
Topics: Acetates; Ammonium Chloride; Animals; Antioxidants; Body Weight; Disease Models, Animal; Ethanol; Et | 2021 |
Glycine suppresses kidney calcium oxalate crystal depositions via regulating urinary excretions of oxalate and citrate.
Topics: Animals; Antiporters; Calcium Oxalate; Case-Control Studies; Cell Line; Citric Acid; Crystallization | 2021 |
Metabolic syndrome contributes to renal injury mediated by hyperoxaluria in a murine model of nephrolithiasis.
Topics: Animals; Calcium Oxalate; Creatinine; Diet, Carbohydrate Loading; Disease Models, Animal; Ethylene G | 2018 |
Antiurolithic effect of olive oil in a mouse model of ethylene glycol-induced urolithiasis.
Topics: Animals; Calcium; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylene Gly | 2017 |
Protective effect of dietary polyphenol caffeic acid on ethylene glycol-induced kidney stones in rats.
Topics: Animals; Antioxidants; Caffeic Acids; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Gene | 2018 |
[Comparative estimation of antilithogenic activity of porcine kidney derived biomedical substance and sodium citrate in experimental urolithiasis].
Topics: Animals; Biological Products; Catalase; Citrates; Disease Models, Animal; Ethylene Glycol; Freeze Dr | 2017 |
Anti-Inflammatory and Anti-Urolithiasis Effects of Polyphenolic Compounds from Quercus gilva Blume.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Ethylene Glycol; | 2017 |
Novel porcine model for calcium oxalate stone formation.
Topics: Ammonium Chloride; Animals; Blood Urea Nitrogen; Calcium Oxalate; Citric Acid; Creatinine; Disease M | 2017 |
SaRNA-mediated activation of TRPV5 reduces renal calcium oxalate deposition in rat via decreasing urinary calcium excretion.
Topics: Animals; Calcium; Calcium Channels; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Humans | 2018 |
Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats.
Topics: Administration, Oral; Animals; Biomarkers; Crystallization; Disease Models, Animal; Ethylene Glycol; | 2018 |
Antiurolithiatic effect of the taraxasterol on ethylene glycol induced kidney calculi in male rats.
Topics: Ammonium Chloride; Animals; Disease Models, Animal; Drugs, Chinese Herbal; Ethylene Glycol; Humans; | 2018 |
Amelioration of hyperoxaluria-induced kidney dysfunction by chemical chaperone 4-phenylbutyric acid.
Topics: Animals; Biomarkers; Calcium Oxalate; Disease Models, Animal; Drug Evaluation, Preclinical; Endoplas | 2019 |
Hydroxycamptothecin nanoparticles based on poly/oligo (ethylene glycol): Architecture effects of nanocarriers on antitumor efficacy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Disease Models, Animal; | 2019 |
Metformin prevents nephrolithiasis formation by inhibiting the expression of OPN and MCP-1 in vitro and in vivo.
Topics: Animals; Body Weight; Cell Death; Chemokine CCL2; Disease Models, Animal; Dogs; Ethylene Glycol; Hum | 2019 |
High-salt diet promotes crystal deposition through hypertension in Dahl salt-sensitive rat model.
Topics: Animals; Blood Pressure; Calcium; Disease Models, Animal; Eplerenone; Ethylene Glycol; Humans; Hydro | 2019 |
Prophylactic effects of quercetin and hyperoside in a calcium oxalate stone forming rat model.
Topics: Animals; Calcium Oxalate; Catalase; Disease Models, Animal; Ethylene Glycol; Kidney; Kidney Calculi; | 2014 |
Antilithiatic effects of crocin on ethylene glycol-induced lithiasis in rats.
Topics: Administration, Oral; Animals; Carotenoids; Citrates; Disease Models, Animal; Ethylene Glycol; Free | 2014 |
Involvement of renin-angiotensin-aldosterone system in calcium oxalate crystal induced activation of NADPH oxidase and renal cell injury.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Angiotensinogen; Animals; Calcium Oxalate; Cell Line; C | 2016 |
[Metabolic therapy of nephrolithiasis in two different rat models of kidney disease].
Topics: Animals; Creatinine; Disease Models, Animal; Ethylene Glycol; Fructose; Hyperglycemia; Male; Nephrol | 2015 |
Proinflammatory and Metabolic Changes Facilitate Renal Crystal Deposition in an Obese Mouse Model of Metabolic Syndrome.
Topics: Adipokines; Animals; Calcium Oxalate; Cell Count; Diet, High-Fat; Disease Models, Animal; Ethylene G | 2015 |
Evaluation of protective effects of diosmin (a citrus flavonoid) in chemical-induced urolithiasis in experimental rats.
Topics: Ammonium Chloride; Animals; Biomarkers; Cytoprotection; Diosmin; Disease Models, Animal; Ethylene Gl | 2016 |
The protective effects of an herbal agent tutukon on ethylene glycol and zinc disk induced urolithiasis model in a rat model.
Topics: Animals; Disease Models, Animal; Ethylene Glycol; Female; Phytotherapy; Plant Extracts; Rats; Rats, | 2016 |
Bergenin attenuates renal injury by reversing mitochondrial dysfunction in ethylene glycol induced hyperoxaluric rat model.
Topics: Animals; Antioxidants; Benzopyrans; Biomarkers; Chemokine CCL2; Creatinine; Cytoprotection; Disease | 2016 |
The Effects of Melatonin on Ethylene Glycol-induced Nephrolithiasis: Role on Osteopontin mRNA Gene Expression.
Topics: Animals; Antioxidants; Biomarkers; Blotting, Western; Disease Models, Animal; Ethylene Glycol; Gene | 2017 |
Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo.
Topics: Animals; Antioxidants; Cell Death; Disease Models, Animal; Dogs; Ethylene Glycol; Humans; Kidney Cal | 2016 |
Chenopodium album Linn. leaves prevent ethylene glycol-induced urolithiasis in rats.
Topics: Animals; Biomarkers; Chenopodium album; Chromatography, High Pressure Liquid; Crystallization; Disea | 2017 |
Protective impact of resveratrol in experimental rat model of hyperoxaluria.
Topics: Animals; Antioxidants; Biopsy, Needle; Disease Models, Animal; Ethylene Glycol; Hyperoxaluria; Immun | 2017 |
Toward a new insight of calcium oxalate stones in Drosophila by micro-computerized tomography.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Drosophila melanogaster; Ethylene Glycol; Humans; | 2018 |
Hyperoxaluria is reduced and nephrocalcinosis prevented with an oxalate-degrading enzyme in mice with hyperoxaluria.
Topics: Administration, Oral; Amino Acid Transport Systems; Animals; Carboxy-Lyases; Chemistry, Pharmaceutic | 2009 |
Antiurolithic effect of lupeol and lupeol linoleate in experimental hyperoxaluria.
Topics: Administration, Oral; Animals; Disease Models, Animal; Ethylene Glycol; Hyperoxaluria; Kidney Calcul | 2008 |
Low-vitamin E diet exacerbates calcium oxalate crystal formation via enhanced oxidative stress in rat hyperoxaluric kidney.
Topics: Animals; Calcium Oxalate; Crystallization; Dietary Supplements; Disease Models, Animal; Ethylene Gly | 2009 |
Effect of thymoquinone on ethylene glycol-induced kidney calculi in rats.
Topics: Animals; Benzoquinones; Calcium Oxalate; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2008 |
Cynodon dactylon extract as a preventive and curative agent in experimentally induced nephrolithiasis.
Topics: Animals; Calcium Oxalate; Crystallization; Cynodon; Disease Models, Animal; Ethylene Glycol; Kidney; | 2009 |
Strain differences in urinary factors that promote calcium oxalate crystal formation in the kidneys of ethylene glycol-treated rats.
Topics: Animals; Body Weight; Calcium Oxalate; Crystallization; Disease Models, Animal; Drinking; Electrolyt | 2009 |
Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats.
Topics: Animals; Antioxidants; Calcium; Disease Models, Animal; Ethanol; Ethylene Glycol; Hyperoxaluria; Kid | 2010 |
Involvement of urinary proteins in the rat strain difference in sensitivity to ethylene glycol-induced renal toxicity.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylene Glycol; | 2010 |
Experimental induction of calcium oxalate nephrolithiasis in mice.
Topics: Animals; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Female; Glyoxylates; Hydroxyproli | 2010 |
Phenotypic correction of a mouse model for primary hyperoxaluria with adeno-associated virus gene transfer.
Topics: Animals; Blotting, Western; Capsid Proteins; Dependovirus; Disease Models, Animal; Ethylene Glycol; | 2011 |
Control of urinary risk factors of stone formation by Salvadora persica in experimental hyperoxaluria.
Topics: Animals; Creatinine; Disease Models, Animal; Ethylene Glycol; Female; Kidney Calculi; Male; Mice; Ox | 2010 |
Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis.
Topics: Aging; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Drosophila melanogaster; E | 2011 |
Phytotherapy in a rat model of hyperoxaluria: the antioxidant effects of quercetin involve serum paraoxonase 1 activation.
Topics: Animals; Antioxidants; Apolipoprotein A-I; Aryldialkylphosphatase; Blotting, Western; Catechin; Chol | 2011 |
Curative treatment with extracts of Bombax ceiba fruit reduces risk of calcium oxalate urolithiasis in rats.
Topics: Animals; Bombax; Calcium; Calcium Oxalate; Disease Models, Animal; Ethylene Glycol; Female; Fruit; H | 2012 |
Preventive and curative effects of Achyranthes aspera Linn. extract in experimentally induced nephrolithiasis.
Topics: Achyranthes; Animals; Biomarkers; Disease Models, Animal; Ethylene Glycol; Humans; Kidney; Male; Nep | 2012 |
Antiurolithiatic activity of saponin rich fraction from the fruits of Solanum xanthocarpum Schrad. & Wendl. (Solanaceae) against ethylene glycol induced urolithiasis in rats.
Topics: Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Ethylene Glycol; Female; Fruit; M | 2012 |
Prophylactic effects of Orthosiphon stamineus Benth. extracts on experimental induction of calcium oxalate nephrolithiasis in rats.
Topics: Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Ethylene Glyco | 2012 |
The biochemical and histopathological investigation of amlodipine in ethylene glycol-induced urolithiasis rat model.
Topics: Amlodipine; Ammonium Chloride; Animals; Calcium Channel Blockers; Calcium Oxalate; Disease Models, A | 2013 |
Counteraction of oxalate induced nitrosative stress by supplementation of l-arginine, a potent antilithic agent.
Topics: Animals; Antioxidants; Arginine; Body Weight; Dietary Supplements; Disease Models, Animal; Ethylene | 2005 |
Study of a rat model for calcium oxalate crystal formation without severe renal damage in selected conditions.
Topics: Acetylglucosaminidase; Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models, | 2005 |
Ethylene glycol induces hyperoxaluria without metabolic acidosis in rats.
Topics: Acidosis; Animals; Carbon Dioxide; Disease Models, Animal; Electrolytes; Ethylene Glycol; Hyperoxalu | 2005 |
Renoprotective effect of grape seeds extract in ethylene glycol induced nephrotoxic mice.
Topics: Animals; Antioxidants; Disease Models, Animal; Ethylene Glycol; Kidney; Kidney Diseases; Lipid Perox | 2005 |
Model uncertainty and risk estimation for experimental studies of quantal responses.
Topics: Animals; Bayes Theorem; Biomedical Research; Data Interpretation, Statistical; Disease Models, Anima | 2005 |
Mild tubular damage induces calcium oxalate crystalluria in a model of subtle hyperoxaluria: Evidence that a second hit is necessary for renal lithogenesis.
Topics: Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Ethylene Glycol; Hyperoxaluria; K | 2006 |
A comparative study on several models of experimental renal calcium oxalate stones formation in rats.
Topics: Ammonium Chloride; Animals; Blood Urea Nitrogen; Calcium; Calcium Gluconate; Calcium Oxalate; Creati | 2007 |
Mitochondrial dysfunction in an animal model of hyperoxaluria: a prophylactic approach with fucoidan.
Topics: Animals; Antioxidants; Citric Acid Cycle; Disease Models, Animal; Ethylene Glycol; Fucus; Glutathion | 2008 |
An alcohol oxidase dipstick rapidly detects methanol in the serum of mice.
Topics: Alcohol Oxidoreductases; Animals; Color; Colorimetry; Cross Reactions; Disease Models, Animal; Ethan | 2007 |
Effect of sulphated polysaccharides on erythrocyte changes due to oxidative and nitrosative stress in experimental hyperoxaluria.
Topics: Animals; Biomarkers; Carbon Radioisotopes; Disease Models, Animal; Erythrocytes; Ethylene Glycol; Fu | 2007 |
Correction of hyperoxaluria by liver repopulation with hepatocytes in a mouse model of primary hyperoxaluria type-1.
Topics: Animals; beta-Galactosidase; Disease Models, Animal; Ethylene Glycol; Hepatocytes; Hyperoxaluria, Pr | 2008 |
Etiology of calcium oxalate nephrolithiasis in rats. I. Can this be a model for human stone formation?
Topics: Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Ethylene Glyco | 1995 |
Etiology of calcium oxalate nephrolithiasis in rats. II. The role of the papilla in stone formation.
Topics: Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Electron Probe | 1995 |
Stone recurrence after shockwave lithotripsy: possible enhanced crystal deposition in traumatized tissue in rabbit model.
Topics: Animals; Crystallization; Disease Models, Animal; Ethylene Glycol; Ethylene Glycols; High-Energy Sho | 1996 |
Enhanced renal vitamin-K-dependent gamma-glutamyl carboxylase activity in experimental rat urolithiasis.
Topics: Animals; Carbon-Carbon Ligases; Dicumarol; Disease Models, Animal; Enzyme Activation; Ethylene Glyco | 1998 |
The effect of takusha, a kampo medicine, on renal stone formation and osteopontin expression in a rat urolithiasis model.
Topics: Animals; Calcium Oxalate; Cholecalciferol; Disease Models, Animal; Drugs, Chinese Herbal; Ethylene G | 1999 |
Inhibitory effects of female sex hormones on urinary stone formation in rats.
Topics: Animals; Blotting, Northern; Calcium; Citric Acid; Crystallization; Disease Models, Animal; Estradio | 1999 |
Expression of bone matrix proteins in urolithiasis model rats.
Topics: Animals; Blood Urea Nitrogen; Blotting, Northern; Calcium Oxalate; Calcium-Binding Proteins; Choleca | 1999 |
Role of macrophages in nephrolithiasis in rats: an analysis of the renal interstitium.
Topics: Ammonium Chloride; Animals; Calcium Oxalate; Crystallization; Disease Models, Animal; Ethylene Glyco | 2000 |
Effects of citrate on renal stone formation and osteopontin expression in a rat urolithiasis model.
Topics: Animals; Blotting, Northern; Chelating Agents; Cholecalciferol; Citric Acid; Disease Models, Animal; | 2001 |