Page last updated: 2024-10-16

ethylene glycol and Body Weight

ethylene glycol has been researched along with Body Weight in 23 studies

Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"75 percent ethylene glycol (v/v) in their drinking water for six weeks to induce hyperoxaluria."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Weight loss, serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation and kidney histopathological studies were done."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Weight loss, rise of serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation were all shown to be prevented by the addition of atorvastatin, polysaccharides, or aqueous extract, respectively."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Ulvan infusions (100 mg/kg body weight), ulvan polysaccharides (100 mg/kg body weight), and atorvastatin (two milligrams/kg body weight) to treat hyperoxaluric rats for four weeks (every other day) were used."8.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"This study sought to determine the relative roles of glycolic acid (GA), a toxicologically important metabolite of ethylene glycol (EG), and metabolic acidosis in causing developmental toxicity in Sprague-Dawley rats."7.70Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis. ( Carney, EW; Dittenber, DA; Dryzga, MD; Freshour, NL, 1999)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."5.91The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"75 percent ethylene glycol (v/v) in their drinking water for six weeks to induce hyperoxaluria."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Weight loss, serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation and kidney histopathological studies were done."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Weight loss, rise of serum creatinine, serum urea, serum uric acid, serum oxalate, kidney oxalate, kidney lipid peroxidation, and kidney DNA fragmentation were all shown to be prevented by the addition of atorvastatin, polysaccharides, or aqueous extract, respectively."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
" Ulvan infusions (100 mg/kg body weight), ulvan polysaccharides (100 mg/kg body weight), and atorvastatin (two milligrams/kg body weight) to treat hyperoxaluric rats for four weeks (every other day) were used."4.31The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"This study sought to determine the relative roles of glycolic acid (GA), a toxicologically important metabolite of ethylene glycol (EG), and metabolic acidosis in causing developmental toxicity in Sprague-Dawley rats."3.70Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis. ( Carney, EW; Dittenber, DA; Dryzga, MD; Freshour, NL, 1999)
"Ethylene Glycol (EG) or Ethylene Glycol Monomethyl Ether (EGMME) was administered by gavage to both sexes of B6C3F1 mice for 4 consecutive days at total doses of 200, 400, and 1000 mg/kg body weight."3.67Comparative effects of ethylene glycol and ethylene glycol monomethyl ether exposure on hematopoiesis and histopathology in B6C3F1 mice. ( Boorman, GA; Canipe, J; Hong, HL; Jameson, CW, 1988)
"Hyperoxaluria caused by ethylene glycol may be prevented by a combination of Ulva lactuca aqueous extract, ulvan polysaccharides, and atorvastatin."1.91The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria. ( Abdel-Gabbar, M; Abdelaziz, MA; Abdelzaher, MH; Ahmed, OM; Geddawy, AI; Ibrahim, SR; Moawd, SA; Mohammad, MR; Mohideen, AP, 2023)
"Nephrolithiasis is a complex disease that results from a combination of factors related to both urine composition and kidney morphoanatomy."1.42Effects of polyphenols from grape seeds on renal lithiasis. ( Costa-Bauzá, A; Fernandez-Cabot, RA; Grases, F; Prieto, RM; Torres, JJ; Tur, F, 2015)
"Hyperoxaluria was induced using 0."1.33Counteraction of oxalate induced nitrosative stress by supplementation of l-arginine, a potent antilithic agent. ( Kalaiselvi, P; Pragasam, V; Srinivasan, S; Sumitra, K; Varalakshmi, P, 2005)
"Ethylene glycol was mixed in the diet at concentrations to deliver constant target dosage levels of 0, 50, 150, 500, or 1000 mg/kg/day for 16 weeks to groups of 10 male Wistar and 10 male F-344 rats based on weekly group mean body weights and feed consumption."1.32Subchronic toxicity of ethylene glycol in Wistar and F-344 rats related to metabolism and clearance of metabolites. ( Corley, RA; Cruzan, G; Deyo, JA; Gingell, R; Hard, GC; McMartin, KE; Mertens, JJ; Snellings, WM, 2004)
" Ethylene glycol was mixed in the diet at concentrations to deliver constant target dosage levels of 0, 50, 150, 500, or 1000 mg/kg/day for 16 weeks to groups of 10 male Wistar and 10 male F-344 rats based on weekly group mean body weights and feed consumption."1.32Subchronic toxicity of ethylene glycol in Wistar and F-344 rats related to metabolism and clearance of metabolites. ( Corley, RA; Cruzan, G; Deyo, JA; Gingell, R; Hard, GC; McMartin, KE; Mertens, JJ; Snellings, WM, 2004)
" Dams were administered EG on Gestation Days 6-15; rats were given 0, 150, 500, 1000, or 2500 mg EG/kg/day; mice were dosed with 0, 50, 150, 500, or 1500 mg EG/kg/day."1.29Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice. ( Fisher, LC; Kubena, MF; Losco, PE; Neeper-Bradley, TL; Tyl, RW; Vrbanic, MA, 1995)
" The "no observable adverse effect level" (NOAEL) for maternal toxicity was therefore 1000 mg/kg/day and the NOAEL for developmental toxicity was at least 2000 mg/kg/day in this study."1.29Developmental toxicity evaluation of ethylene glycol by gavage in New Zealand white rabbits. ( Heindel, JJ; Marr, MC; Myers, CB; Price, CJ; Schwetz, BA; Seely, JC; Tyl, RW, 1993)
" All four chemicals tested, boric acid, ethylene glycol, ethylene glycol monomethyl ether, and theophylline, were found to be toxic to development or reproduction when tested previously by conventional developmental toxicity or continuous breeding protocols."1.28Assessment of a short-term reproductive and developmental toxicity screen. ( Chapin, RE; Harris, MW; Jokinen, MP; Lockhart, AC, 1992)
" A second group of females was dosed daily for 19 days."1.28Assessment of a short-term reproductive and developmental toxicity screen. ( Chapin, RE; Harris, MW; Jokinen, MP; Lockhart, AC, 1992)
"5, or 1% ethylene glycol by continuous administration in drinking water for male and female mice were selected from the general toxic responses observed in a 14-day pilot study."1.27Reproductive and developmental toxicity of ethylene glycol in the mouse. ( Gulati, DK; Hommel-Barnes, L; Lamb, JC; Maronpot, RR; Russell, VS; Sabharwal, PS, 1985)
" The dosage amounts of 0, 0."1.27Reproductive and developmental toxicity of ethylene glycol in the mouse. ( Gulati, DK; Hommel-Barnes, L; Lamb, JC; Maronpot, RR; Russell, VS; Sabharwal, PS, 1985)
"Timed-pregnant CD rats and CD-1 mice were dosed by gavage with ethylene glycol (EG) in distilled water on gestational days (gd) 6 through 15 (0, 1250, 2500, or 5000 mg kg-1 day-1 for rats; and 0, 750, 1500, or 3000 mg kg-1 day-1 for mice)."1.27The developmental toxicity of ethylene glycol in rats and mice. ( Kimmel, CA; Marr, MC; Price, CJ; Tyl, RW, 1985)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19907 (30.43)18.7374
1990's9 (39.13)18.2507
2000's3 (13.04)29.6817
2010's2 (8.70)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Abdelaziz, MA1
Ahmed, OM1
Abdel-Gabbar, M1
Mohammad, MR1
Ibrahim, SR1
Abdelzaher, MH1
Mohideen, AP1
Moawd, SA1
Geddawy, AI1
Marhoume, FZ1
Aboufatima, R1
Zaid, Y1
Limami, Y1
Duval, RE1
Laadraoui, J1
Belbachir, A1
Chait, A1
Bagri, A1
Yang, X1
Yang, T1
Li, J2
Yang, R1
Qi, S1
Zhao, Y1
Li, L1
Zhang, X1
Yang, K1
Xu, Y1
Liu, C1
Grases, F1
Prieto, RM1
Fernandez-Cabot, RA1
Costa-Bauzá, A1
Tur, F1
Torres, JJ1
Li, Y1
McMartin, KE2
Cruzan, G1
Corley, RA1
Hard, GC1
Mertens, JJ1
Snellings, WM1
Gingell, R1
Deyo, JA1
Pragasam, V1
Kalaiselvi, P1
Sumitra, K1
Srinivasan, S1
Varalakshmi, P1
Melnick, RL1
Neeper-Bradley, TL1
Tyl, RW4
Fisher, LC2
Kubena, MF1
Vrbanic, MA1
Losco, PE2
Ballantyne, B1
Fait, DL1
Dodd, DE1
Klonne, DR1
Pritts, IM1
Price, CJ2
Marr, MC2
Myers, CB1
Seely, JC1
Heindel, JJ1
Schwetz, BA1
Muthukumar, A1
Selvam, R1
George, EO1
Wu, H1
Carney, EW1
Freshour, NL1
Dittenber, DA1
Dryzga, MD1
Harris, MW1
Chapin, RE1
Lockhart, AC1
Jokinen, MP1
Lee, YH1
Huang, WC1
Chiang, H1
Chen, MT1
Huang, JK1
Chang, LS1
Hong, HL1
Canipe, J1
Jameson, CW1
Boorman, GA1
Johnson, EM1
DePass, LR2
Garman, RH1
Woodside, MD2
Giddens, WE1
Maronpot, RR3
Weil, CS2
Lamb, JC1
Gulati, DK1
Russell, VS1
Hommel-Barnes, L1
Sabharwal, PS1
Kimmel, CA1

Other Studies

23 other studies available for ethylene glycol and Body Weight

ArticleYear
The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:8

    Topics: Animals; Antioxidants; Atorvastatin; Body Weight; Creatinine; Ethylene Glycol; Humans; Hyperoxaluria

2023
Antioxidant and Polyphenol-Rich Ethanolic Extract of
    Molecules (Basel, Switzerland), 2021, Feb-14, Volume: 26, Issue:4

    Topics: Acetates; Ammonium Chloride; Animals; Antioxidants; Body Weight; Disease Models, Animal; Ethanol; Et

2021
Metformin prevents nephrolithiasis formation by inhibiting the expression of OPN and MCP-1 in vitro and in vivo.
    International journal of molecular medicine, 2019, Volume: 43, Issue:4

    Topics: Animals; Body Weight; Cell Death; Chemokine CCL2; Disease Models, Animal; Dogs; Ethylene Glycol; Hum

2019
Effects of polyphenols from grape seeds on renal lithiasis.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Ammonium Chloride; Animals; Body Weight; Calcium; Catechin; Ethylene Glycol; Grape Seed Extract; Kid

2015
Strain differences in urinary factors that promote calcium oxalate crystal formation in the kidneys of ethylene glycol-treated rats.
    American journal of physiology. Renal physiology, 2009, Volume: 296, Issue:5

    Topics: Animals; Body Weight; Calcium Oxalate; Crystallization; Disease Models, Animal; Drinking; Electrolyt

2009
Subchronic toxicity of ethylene glycol in Wistar and F-344 rats related to metabolism and clearance of metabolites.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:2

    Topics: Animals; Biotransformation; Body Weight; Diet; Drinking; Ethylene Glycol; Glycolates; Kidney; Kidney

2004
Counteraction of oxalate induced nitrosative stress by supplementation of l-arginine, a potent antilithic agent.
    Clinica chimica acta; international journal of clinical chemistry, 2005, Volume: 354, Issue:1-2

    Topics: Animals; Antioxidants; Arginine; Body Weight; Dietary Supplements; Disease Models, Animal; Ethylene

2005
Toxicities of ethylene glycol and ethylene glycol monoethyl ether in Fischer 344/N rats and B6C3F1 mice.
    Environmental health perspectives, 1984, Volume: 57

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Ethylene Glycol; Ethylene Glycols; Female; Ki

1984
Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 27, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Ethylene Glycol; Ethylene Glycols; Female; Fetus;

1995
Evaluation of the developmental toxicity of ethylene glycol aerosol in CD-1 mice by nose-only exposure.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 27, Issue:1

    Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Aerosols; Animals; Body Weight; Dose-Respon

1995
Developmental toxicity evaluation of ethylene glycol by gavage in New Zealand white rabbits.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1993, Volume: 20, Issue:4

    Topics: Animals; Body Weight; Drinking; Ethylene Glycol; Ethylene Glycols; Female; Gestational Age; Intubati

1993
Reproductive toxicology. Ethylene glycol.
    Environmental health perspectives, 1997, Volume: 105 Suppl 1

    Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Body Weight; Bone and Bones; Dose-Response Relat

1997
Renal injury mediated calcium oxalate nephrolithiasis: role of lipid peroxidation.
    Renal failure, 1997, Volume: 19, Issue:3

    Topics: Animals; Body Weight; Buthionine Sulfoximine; Calcium Oxalate; Ethylene Glycol; Ethylene Glycols; ga

1997
Testing for treatment related trend with partially exchangeable clustered data.
    Biometrics, 1997, Volume: 53, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Biometry; Body Weight; Cluster Analysis; Data Interpretation,

1997
Ethylene glycol developmental toxicity: unraveling the roles of glycolic acid and metabolic acidosis.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 50, Issue:1

    Topics: Acidosis; Animals; Body Weight; Bone and Bones; Ethylene Glycol; Female; Fetus; Glycolates; Keratoly

1999
Assessment of a short-term reproductive and developmental toxicity screen.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 19, Issue:2

    Topics: Animals; Body Weight; Boric Acids; Ethylene Glycol; Ethylene Glycols; Female; Male; Mice; Organ Size

1992
Determinant role of testosterone in the pathogenesis of urolithiasis in rats.
    The Journal of urology, 1992, Volume: 147, Issue:4

    Topics: Animals; Body Weight; Castration; Ethylene Glycol; Ethylene Glycols; Female; Kidney; Male; Rats; Rat

1992
Comparative effects of ethylene glycol and ethylene glycol monomethyl ether exposure on hematopoiesis and histopathology in B6C3F1 mice.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1988, Volume: 8, Issue:7 Spec No

    Topics: Animals; Blood Cell Count; Body Weight; Bone Marrow; Ethylene Glycol; Ethylene Glycols; Female; Hema

1988
Ethylene glycol toxicology.
    Toxicology and applied pharmacology, 1986, Jun-15, Volume: 84, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Ethylene Glycol; Ethylene Glycols; Female; Fetus;

1986
Chronic toxicity and oncogenicity studies of ethylene glycol in rats and mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 7, Issue:4

    Topics: Animals; Body Weight; Carcinogens; Drinking; Eating; Ethylene Glycol; Ethylene Glycols; Female; Kidn

1986
Three-generation reproduction and dominant lethal mutagenesis studies of ethylene glycol in the rat.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 7, Issue:4

    Topics: Animals; Animals, Newborn; Body Weight; Ethylene Glycol; Ethylene Glycols; Female; Fertility; Genes,

1986
Reproductive and developmental toxicity of ethylene glycol in the mouse.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:1

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drinking Behavior; Embryonic and Fetal Devel

1985
The developmental toxicity of ethylene glycol in rats and mice.
    Toxicology and applied pharmacology, 1985, Volume: 81, Issue:1

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Ethylene Glycol; Ethylene Glycols; Female; F

1985