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ethylene glycol and Acute Liver Injury, Drug-Induced

ethylene glycol has been researched along with Acute Liver Injury, Drug-Induced in 7 studies

Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.

Research Excerpts

ExcerptRelevanceReference
"Propolis extract has a potential protective effect against ethylene glycol induced hepatotoxicity and nephrotoxicity and has a potential to treat and prevent urinary calculus, crystaluria and proteinuria."7.83Protective Effect of Propolis in Proteinuria, Crystaluria, Nephrotoxicity and Hepatotoxicity Induced by Ethylene Glycol Ingestion. ( Al Waili, N; Al-Waili, H; Bakour, M; El Menyiy, N; Lyoussi, B, 2016)
"Propolis extract has a potential protective effect against ethylene glycol induced hepatotoxicity and nephrotoxicity and has a potential to treat and prevent urinary calculus, crystaluria and proteinuria."3.83Protective Effect of Propolis in Proteinuria, Crystaluria, Nephrotoxicity and Hepatotoxicity Induced by Ethylene Glycol Ingestion. ( Al Waili, N; Al-Waili, H; Bakour, M; El Menyiy, N; Lyoussi, B, 2016)
"Antidote ethanol is the basic treatment in ethylene glycol (EG) poisoning."3.73Course of intoxications due to concurrent ethylene glycol and ethanol ingestion. ( Krenová, M; Pelclová, D, 2005)
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."1.36Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)
"Ethylene glycol (EG) is a toxic chemical found in antifreeze and heat exchangers."1.28The toxicokinetics of 1,3-butylene glycol versus ethanol in the treatment of ethylene glycol poisoning. ( Boelen, LJ; Cox, SK; Ferslew, KE, 1992)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greene, N1
Fisk, L1
Naven, RT1
Note, RR1
Patel, ML1
Pelletier, DJ1
Ekins, S1
Williams, AJ1
Xu, JJ1
El Menyiy, N1
Al Waili, N1
Bakour, M1
Al-Waili, H1
Lyoussi, B1
Krenová, M1
Pelclová, D1
Ozcan, K1
Ozen, H1
Karaman, M1
Borowiak, K1
Cox, SK1
Ferslew, KE1
Boelen, LJ1

Trials

1 trial available for ethylene glycol and Acute Liver Injury, Drug-Induced

ArticleYear
[Activity of choline esterases in blood cells and serum and cobalt activated acylase in toxic and non-toxic liver damage].
    Annales Academiae Medicae Stetinensis, 1995, Volume: 41

    Topics: Adolescent; Adult; Aged; Amanita; Amidohydrolases; Chemical and Drug Induced Liver Injury; Cholinest

1995

Other Studies

6 other studies available for ethylene glycol and Acute Liver Injury, Drug-Induced

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Protective Effect of Propolis in Proteinuria, Crystaluria, Nephrotoxicity and Hepatotoxicity Induced by Ethylene Glycol Ingestion.
    Archives of medical research, 2016, Volume: 47, Issue:7

    Topics: Animals; Chemical and Drug Induced Liver Injury; Ethylene Glycol; Kidney; Kidney Diseases; Male; Pla

2016
Course of intoxications due to concurrent ethylene glycol and ethanol ingestion.
    Przeglad lekarski, 2005, Volume: 62, Issue:6

    Topics: Adolescent; Adult; Antidotes; Central Nervous System Depressants; Chemical and Drug Induced Liver In

2005
Nitrosative tissue damage and apoptotic cell death in kidneys and livers of naturally ethylene glycol (antifreeze)-poisoned geese.
    Avian pathology : journal of the W.V.P.A, 2007, Volume: 36, Issue:4

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Ethylene Glycol; Geese; Kidney; Kidney D

2007
The toxicokinetics of 1,3-butylene glycol versus ethanol in the treatment of ethylene glycol poisoning.
    Veterinary and human toxicology, 1992, Volume: 34, Issue:1

    Topics: Alcohol Dehydrogenase; Animals; Butylene Glycols; Chemical and Drug Induced Liver Injury; Drinking;

1992