ethylene glycol has been researched along with Abnormalities, Drug-Induced in 14 studies
Ethylene Glycol: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins.
ethanediol : Any diol that is ethane or substituted ethane carrying two hydroxy groups.
ethylene glycol : A 1,2-glycol compound produced via reaction of ethylene oxide with water.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Severe adverse effects have been noted with pharmaceutical formulations containing diethylene glycol monoethyl-ethers and this led to withdrawal from the French market." | 2.44 | [Hormone replacement therapy: toxicity of glycol ethers]. ( Biggi-Bernard, U; Descotes, J; Timour, Q, 2007) |
| "We apply the model to an influenza study with repeated responses in which some pairs are negatively associated and to a developmental toxicity study with continuation-ratio logits applied to an ordinal response with clustered observations." | 1.31 | Random effects modeling of multiple binomial responses using the multivariate binomial logit-normal distribution. ( Agresti, A; Coull, BA, 2000) |
| " Dams were administered EG on Gestation Days 6-15; rats were given 0, 150, 500, 1000, or 2500 mg EG/kg/day; mice were dosed with 0, 50, 150, 500, or 1500 mg EG/kg/day." | 1.29 | Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice. ( Fisher, LC; Kubena, MF; Losco, PE; Neeper-Bradley, TL; Tyl, RW; Vrbanic, MA, 1995) |
| "Ethylene glycol (EG) is a major industrial chemical, shown to be teratogenic at high doses by gavage in rodents." | 1.29 | Evaluation of the developmental toxicity of ethylene glycol aerosol in the CD rat and CD-1 mouse by whole-body exposure. ( Ballantyne, B; Dodd, DE; Fait, DL; Fisher, LC; Klonne, DR; Pritts, IM; Savine, TA; Tyl, RW, 1995) |
| "The Rai and Van Ryzin dose-response model proposed for teratology experiments has been characterized for its appropriateness and applicability in modeling the dichotomous response data from developmental toxicity studies." | 1.28 | Characterization of a developmental toxicity dose-response model. ( Faustman, EM; Kimmel, CA; Smith, WP; Wellington, DG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carney, EW | 1 |
| Tornesi, B | 1 |
| Markham, DA | 1 |
| Rasoulpour, RJ | 1 |
| Moore, N | 1 |
| Chen, Z | 1 |
| Zhang, B | 1 |
| Albert, PS | 1 |
| Timour, Q | 1 |
| Biggi-Bernard, U | 1 |
| Descotes, J | 1 |
| Neeper-Bradley, TL | 1 |
| Tyl, RW | 3 |
| Fisher, LC | 3 |
| Kubena, MF | 1 |
| Vrbanic, MA | 1 |
| Losco, PE | 2 |
| Ballantyne, B | 2 |
| Fait, DL | 2 |
| Dodd, DE | 2 |
| Klonne, DR | 2 |
| Pritts, IM | 2 |
| Savine, TA | 1 |
| George, EO | 1 |
| Wu, H | 1 |
| Coull, BA | 1 |
| Agresti, A | 1 |
| Klug, S | 1 |
| Merker, HJ | 1 |
| Jäckh, R | 1 |
| Khera, KS | 1 |
| Faustman, EM | 1 |
| Wellington, DG | 1 |
| Smith, WP | 1 |
| Kimmel, CA | 1 |
| Johnson, EM | 1 |
1 review available for ethylene glycol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Hormone replacement therapy: toxicity of glycol ethers].
Topics: Abnormalities, Drug-Induced; Ethyl Ethers; Ethylene Glycol; Female; Fertility; Hormone Replacement T | 2007 |
13 other studies available for ethylene glycol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Species-specificity of ethylene glycol-induced developmental toxicity: toxicokinetic and whole embryo culture studies in the rabbit.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Embryonic Development; Ethylene Glycol; Fem | 2008 |
A joint modeling approach to data with informative cluster size: robustness to the cluster size model.
Topics: Abnormalities, Drug-Induced; Animals; Bias; Biomedical Research; Cluster Analysis; Epidemiologic Res | 2011 |
Determination of a no-observed-effect level for developmental toxicity of ethylene glycol administered by gavage to CD rats and CD-1 mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Ethylene Glycol; Ethylene Glycols; Female; Fetus; | 1995 |
Evaluation of the developmental toxicity of ethylene glycol aerosol in CD-1 mice by nose-only exposure.
Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Aerosols; Animals; Body Weight; Dose-Respon | 1995 |
Evaluation of the developmental toxicity of ethylene glycol aerosol in the CD rat and CD-1 mouse by whole-body exposure.
Topics: Abnormalities, Drug-Induced; Administration, Inhalation; Aerosols; Animals; Drug Evaluation, Preclin | 1995 |
Reproductive toxicology. Ethylene glycol.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Bone and Bones; Brain; Dose-Response Relationshi | 1997 |
Reproductive toxicology. Ethylene glycol.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Body Weight; Bone and Bones; Dose-Response Relat | 1997 |
Testing for treatment related trend with partially exchangeable clustered data.
Topics: Abnormalities, Drug-Induced; Animals; Biometry; Body Weight; Cluster Analysis; Data Interpretation, | 1997 |
Random effects modeling of multiple binomial responses using the multivariate binomial logit-normal distribution.
Topics: Abnormalities, Drug-Induced; Animals; Biometry; Epidemiologic Methods; Ethylene Glycol; Female; Huma | 2000 |
Effects of ethylene glycol and metabolites on in vitro development of rat embryos during organogenesis.
Topics: Abnormalities, Drug-Induced; Acetaldehyde; Animal Testing Alternatives; Animals; Dose-Response Relat | 2001 |
Chemically induced alterations in maternal homeostasis and histology of conceptus: their etiologic significance in rat fetal anomalies.
Topics: Abnormalities, Drug-Induced; Acid-Base Equilibrium; Animals; Cadmium; Cadmium Chloride; Catheterizat | 1991 |
Characterization of a developmental toxicity dose-response model.
Topics: Abnormalities, Drug-Induced; Animals; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Envi | 1989 |
Ethylene glycol toxicology.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Ethylene Glycol; Ethylene Glycols; Female; Fetus; | 1986 |