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ethylene dimethanesulfonate and Aging

ethylene dimethanesulfonate has been researched along with Aging in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's8 (57.14)18.2507
2000's0 (0.00)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, H; Ge, R; Guo, J; Lian, Q; Papadopoulos, V; Zirkin, BR1
Davidoff, MS; Middendorff, R; Mukhopadhyay, AK; Müller, D1
Ewing, L; Gray, LE; Kelce, W; Klinefelter, G; Laskey, J; Ostby, J1
Ewing, LL; Kelce, WR; Klinefelter, GR; Laskey, JW1
Ewing, LL; Gray, LE; Kelce, WR; Klinefelter, GR; Laskey, JW1
Bremner, WJ; Millar, MR; Saunders, PT; Sharpe, RM1
Aguilar, E; Pinilla, L; Tena-Sempere, M1
Chen, H; Huhtaniemi, I; Zirkin, BR1
Huhtaniemi, I; Kero, J; Rannikko, A; Tena-Sempere, M; Yan, W1
Ewing, LL; Kelce, WR; Zirkin, BR1
de Kretser, D; Kerr, J; Risbridger, G1
Hoogerbrugge, JW; Rommerts, FF; Teerds, KJ1
Kerr, JB; Knell, CM; Risbridger, GP1
Bartlett, JM; Sharpe, RM1

Other Studies

14 other study(ies) available for ethylene dimethanesulfonate and Aging

ArticleYear
Steroidogenic fate of the Leydig cells that repopulate the testes of young and aged Brown Norway rats after elimination of the preexisting Leydig cells.
    Experimental gerontology, 2015, Volume: 72

    Topics: Aging; Animals; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Rats; Rats, Inbred BN; Testosterone

2015
Cyclic GMP signaling in rat urinary bladder, prostate, and epididymis: tissue-specific changes with aging and in response to Leydig cell depletion.
    Reproduction (Cambridge, England), 2011, Volume: 142, Issue:2

    Topics: Aging; Androgens; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Cytosol; Down-Regulation; Epididymis; Leydig Cells; Male; Mesylates; Organ Specificity; Prostate; Rats; Rats, Wistar; Second Messenger Systems; Spermatogenesis; Up-Regulation; Urinary Bladder

2011
Hamster Leydig cells are less sensitive to ethane dimethanesulfonate when compared to rat Leydig cells both in vivo and in vitro.
    Toxicology and applied pharmacology, 1995, Volume: 130, Issue:2

    Topics: Aging; Animals; Cricetinae; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Leydig Cells; Male; Mesocricetus; Mesylates; Organ Size; Rats; Species Specificity; Testis; Testosterone

1995
Effects of ethane dimethanesulfonate (EDS) on adult and immature rabbit Leydig cells: comparison with EDS-treated rat Leydig cells.
    Biology of reproduction, 1994, Volume: 50, Issue:5

    Topics: Aging; Animals; Bucladesine; Cell Death; Chorionic Gonadotropin; Culture Techniques; Leydig Cells; Male; Mesylates; Microscopy, Electron; Rabbits; Rats; Rats, Sprague-Dawley; Testis; Testosterone

1994
Distribution of [14C]ethane dimethanesulfonate in immature and adult male rats following an acute exposure.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1994, Volume: 22, Issue:3

    Topics: Aging; Animals; Chromatography, Thin Layer; Epididymis; Genitalia, Male; Half-Life; Male; Mesylates; Rats; Rats, Sprague-Dawley; Testis; Tissue Distribution

1994
Immunohistochemical localization of androgen receptors in the rat testis: evidence for stage-dependent expression and regulation by androgens.
    Endocrinology, 1994, Volume: 135, Issue:3

    Topics: Acetates; Aging; Androgens; Animals; Immunohistochemistry; Male; Mesylates; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Reference Values; Spermatogenesis; Testis; Tissue Distribution

1994
Follicle-stimulating hormone and luteinizing hormone secretion in male rats orchidectomized or injected with ethylene dimethane sulfonate.
    Endocrinology, 1993, Volume: 133, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Chorionic Gonadotropin; Estradiol; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Orchiectomy; Rats; Rats, Wistar; Sertoli Cells; Tamoxifen; Testis; Testosterone

1993
Depletion and repopulation of Leydig cells in the testes of aging brown Norway rats.
    Endocrinology, 1996, Volume: 137, Issue:8

    Topics: Aging; Animals; Bucladesine; Cell Count; Hydroxycholesterols; Leydig Cells; Luteinizing Hormone; Male; Mesylates; Rats; Rats, Inbred BN; Testis; Testosterone; Time Factors

1996
The pattern of inhibin/activin alpha- and betaB-subunit messenger ribonucleic acid expression in rat testis after selective Leydig cell destruction by ethylene dimethane sulfonate.
    Endocrinology, 1999, Volume: 140, Issue:12

    Topics: Activins; Aging; Animals; Blotting, Northern; Cryptorchidism; Gene Expression; In Situ Hybridization; Inhibins; Kinetics; Leydig Cells; Male; Mesylates; Rats; Rats, Sprague-Dawley; RNA, Messenger; Testis

1999
Immature rat Leydig cells are intrinsically less sensitive than adult Leydig cells to ethane dimethanesulfonate.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: Aging; Androgens; Animals; Cells, Cultured; Leydig Cells; Male; Mesylates; Perfusion; Rats; Testis

1991
Differential effects of the destruction of Leydig cells by administration of ethane dimethane sulphonate to postnatal rats.
    Biology of reproduction, 1989, Volume: 40, Issue:4

    Topics: Aging; Animals; Body Weight; Cell Survival; Chorionic Gonadotropin; Leydig Cells; Male; Mesylates; Organ Size; Rats; Rats, Inbred Strains; Seminiferous Epithelium; Seminiferous Tubules; Spermatogenesis; Testis; Testosterone

1989
In vitro effects of ethylene-dimethane sulfonate (EDS) on Leydig cells: inhibition of steroid production and cytotoxic effects are dependent on species and age of rat.
    Molecular and cellular endocrinology, 1988, Volume: 55, Issue:1

    Topics: Adenosine Triphosphate; Aging; Alkylating Agents; Animals; Cells, Cultured; Hydroxycholesterols; Leydig Cell Tumor; Leydig Cells; Liver; Luteinizing Hormone; Male; Mesylates; Mice; Pregnenolone; Proteins; Rats; Sertoli Cells; Sexual Maturation; Species Specificity; Testicular Neoplasms; Testis

1988
Stimulation of interstitial cell growth after selective destruction of foetal Leydig cells in the testis of postnatal rats.
    Cell and tissue research, 1988, Volume: 252, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Leydig Cells; Male; Mesylates; Rats; Rats, Inbred Strains; Testis; Testosterone

1988
Changes in the secretion of ABP into testicular interstitial fluid with age and in situations of impaired spermatogenesis.
    International journal of andrology, 1987, Volume: 10, Issue:5

    Topics: Aging; Androgen-Binding Protein; Animals; Cryptorchidism; Follicle Stimulating Hormone; Hot Temperature; Leydig Cells; Male; Mesylates; Rats; Rats, Inbred Strains; Spermatogenesis; Testosterone

1987