ethylene dichloride has been researched along with Acute Liver Injury, Drug-Induced in 9 studies
ethylene dichloride: RN given refers to 1,2-isomer; structure given in first source
1,2-dichloroethane : A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Subacute exposure to DCE can cause severe toxic encephalopathy and has obvious toxic effects on the liver." | 1.48 | 1,2-Dichloroethane-induced hepatotoxicity and apoptosis by inhibition of ERK 1/2 pathways. ( Jiang, S; Li, W; Pang, Y; Qi, G; Zhou, Y, 2018) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Zeng, N | 2 |
| Zhang, Z | 1 |
| Jiang, H | 2 |
| Li, R | 2 |
| Chang, C | 1 |
| Wang, F | 2 |
| Xu, D | 2 |
| Fan, Q | 2 |
| Wang, T | 2 |
| Xiao, Y | 1 |
| Chen, W | 2 |
| Shan, Z | 1 |
| Huang, Z | 2 |
| Wang, Q | 2 |
| Rong, W | 1 |
| Li, G | 1 |
| Guo, T | 1 |
| Zeng, L | 1 |
| Huang, M | 1 |
| Zheng, J | 1 |
| Lu, F | 1 |
| Hu, Q | 1 |
| Pang, Y | 1 |
| Qi, G | 1 |
| Jiang, S | 1 |
| Zhou, Y | 1 |
| Li, W | 1 |
| Yang, G | 1 |
| Shi, L | 1 |
| Zhang, J | 1 |
| Tan, X | 1 |
| Wang, G | 1 |
| Lv, X | 1 |
| Jin, Y | 1 |
| Lebedev, VP | 1 |
| Melikhova, MV | 1 |
| Kolbasov, SE | 1 |
| Stroĭkova, GV | 1 |
| Zamuruev, ON | 1 |
| Igwe, OJ | 1 |
| Hee, SS | 1 |
| Wagner, WD | 1 |
| Condie, LW | 1 |
1 review available for ethylene dichloride and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Target organ toxicology of halocarbons commonly found contaminating drinking water.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chronic Disease; Et | 1985 |
8 other studies available for ethylene dichloride and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Ethylene Dichl | 2019 |
Aberrant expression of miR-451a contributes to 1,2-dichloroethane-induced hepatic glycerol gluconeogenesis disorder by inhibiting glycerol kinase expression in NIH Swiss mice.
Topics: Animals; Cell Line; Chemical and Drug Induced Liver Injury; Ethylene Dichlorides; Gene Expression Pr | 2018 |
1,2-Dichloroethane-induced hepatotoxicity and apoptosis by inhibition of ERK 1/2 pathways.
Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Environmental Po | 2018 |
[Roles of CYP2E1 in liver damage induced by 1,2-dichloroethane].
Topics: Alanine Transaminase; Allyl Compounds; Animals; Aspartate Aminotransferases; Chemical and Drug Induc | 2016 |
[Effect of the transcranial electrical stimulation of the endorphinergic brain structures on the functional activity of hepatocytes after toxic exposure].
Topics: Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Electric Sti | 2000 |
Interaction between 1,2-dichloroethane and tetraethylthiuram disulfide (disulfiram). II. Hepatotoxic manifestations with possible mechanism of action.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Disulf | 1986 |