ethylene chlorohydrin has been researched along with Brain Neoplasms in 2 studies
Ethylene Chlorohydrin: Used as a solvent, in the manufacture of insecticides, and for treating sweet potatoes before planting. May cause nausea, vomiting, pains in head and chest, stupefaction. Irritates mucous membranes and causes kidney and liver degeneration.
chloroethanol : An organochlorine compound that is ethanol substituted by at least one chloro group.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In all, 40 pharmacokinetic determinations of fotemustine were made at dose levels ranging from 2 x 300 to 2 x 500 mg/m2." | 6.67 | Phase I pharmacokinetics study of high-dose fotemustine and its metabolite 2-chloroethanol in patients with high-grade gliomas. ( Biron, P; Evene, E; Giroux, B; Gordon, B; Lucas, C; Mornex, F; Richards, R; Roux, N; Solere, P; Tranchand, B, 1993) |
| " In all, 40 pharmacokinetic determinations of fotemustine were made at dose levels ranging from 2 x 300 to 2 x 500 mg/m2." | 2.67 | Phase I pharmacokinetics study of high-dose fotemustine and its metabolite 2-chloroethanol in patients with high-grade gliomas. ( Biron, P; Evene, E; Giroux, B; Gordon, B; Lucas, C; Mornex, F; Richards, R; Roux, N; Solere, P; Tranchand, B, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tranchand, B | 1 |
| Lucas, C | 1 |
| Biron, P | 1 |
| Giroux, B | 1 |
| Gordon, B | 1 |
| Richards, R | 1 |
| Solere, P | 1 |
| Roux, N | 1 |
| Evene, E | 1 |
| Mornex, F | 1 |
| Zhou, Q | 1 |
| Verdoorn, TA | 1 |
| Lovinger, DM | 1 |
1 trial available for ethylene chlorohydrin and Brain Neoplasms
| Article | Year |
|---|---|
Phase I pharmacokinetics study of high-dose fotemustine and its metabolite 2-chloroethanol in patients with high-grade gliomas.
Topics: Adult; Antineoplastic Agents; Bone Marrow Transplantation; Brain Neoplasms; Ethylene Chlorohydrin; F | 1993 |
1 other study available for ethylene chlorohydrin and Brain Neoplasms
| Article | Year |
|---|---|
Alcohols potentiate the function of 5-HT3 receptor-channels on NCB-20 neuroblastoma cells by favouring and stabilizing the open channel state.
Topics: Alcohols; Algorithms; Brain Neoplasms; Butanols; Central Nervous System Depressants; Computer Simula | 1998 |