Page last updated: 2024-08-23

ethylcholine aziridinium and Disease Models, Animal

ethylcholine aziridinium has been researched along with Disease Models, Animal in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19909 (34.62)18.7374
1990's5 (19.23)18.2507
2000's9 (34.62)29.6817
2010's2 (7.69)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Ban, YH; Choi, EK; Joo, SS; Kim, TM; Kim, YB; Park, D1
Bachurin, SO; Lermontova, NN; Nikolaeva, NS; Serkova, TP; Shevtsova, EF; Van'kin, GI; Vasilieva, NA1
Ban, YH; Cha, Y; Choi, EK; Guo, H; Jang, GY; Jang, SK; Jeong, HS; Joo, SS; Kim, YB; Lee, JY; Lee, SH; Park, D; Yeon, S1
Blei, K; Dirnagl, U; Harms, C; Harms, U; Hörtnagl, H; Kapinya, KJ; Katchanov, J1
Dudas, B; Hanin, I; Rose, M; Wülfert, E1
Cornelli, U; Dudas, B; Hanin, I; Rose, M1
Daniel, C; Geisslinger, G; Radeke, HH; Sartory, N; Stein, JM; Zahn, N1
Berdiev, RK; Chepurnov, SA; Chepurnova, NE; van Luijtelaar, G; Veening, JG1
Chakravarti, S; Wu, F1
Bessho, T; Eguchi, J; Komatsu, T; Saito, K; Takashina, K1
Potter, PE; Thorne, B1
Hanin, I2
El Tamer, A; Hanin, I; Wülfert, E1
Bartolomeo, AC; Boast, CA; Morris, H1
Kubo, T; Nakamura, S; Nishiike, S; Takeda, N; Uno, A; Yamatodani, A1
Bachurin, SO; Lermontova, NN; Lukoyanov, NV; Lukoyanova, EA; Serkova, TP1
Arendash, GW; Meyer, EM; Mouton, PR1
Brandeis, R; Dachir, S; Fisher, A; Heldman, E; Karton, I; Levy, A; Pittel, Z; Sapir, M1
Fisher, A; Hanin, I1
Iga, Y; Kawanishi, G; Mizobe, F; Nakahara, N1
Ikeda, H; Okano, T; Yamashita, M; Yoshimura, K1
Cuello, AC; Stephens, PH; Tagari, P1
Lammers, AJ; Steinbusch, HW; Tonnaer, JA; Wieringa, JH1
Jarrard, LE; Kant, GJ; Levy, A; Meyerhoff, JL1
Abraham, DJ; Hanin, I; Mistry, JS1

Reviews

3 review(s) available for ethylcholine aziridinium and Disease Models, Animal

ArticleYear
The AF64A model of cholinergic hypofunction: an update.
    Life sciences, 1996, Volume: 58, Issue:22

    Topics: Animals; Aziridines; Brain; Choline; Choline Deficiency; Cholinergic Antagonists; Disease Models, Animal; Neurons; Neurotoxins; Synaptic Transmission

1996
Cholinergic toxins and Alzheimer's disease.
    Annals of the New York Academy of Sciences, 1992, May-11, Volume: 648

    Topics: Acetylcholine; Alzheimer Disease; Animals; Aziridines; Choline; Disease Models, Animal; Humans; Neurotoxins; Parasympathomimetics

1992
Potential animal models for senile dementia of Alzheimer's type, with emphasis on AF64A-induced cholinotoxicity.
    Annual review of pharmacology and toxicology, 1986, Volume: 26

    Topics: Aged; Aging; Aluminum; Alzheimer Disease; Animals; Aziridines; Choline; Disease Models, Animal; Haplorhini; Hemicholinium 3; Humans; Neuromuscular Blocking Agents; Neurotoxins; Parasympathetic Nervous System; Scopolamine

1986

Other Studies

23 other study(ies) available for ethylcholine aziridinium and Disease Models, Animal

ArticleYear
Effectiveness of Combinational Treatments for Alzheimer's Disease with Human Neural Stem Cells and Microglial Cells Over-Expressing Functional Genes.
    International journal of molecular sciences, 2023, May-31, Volume: 24, Issue:11

    Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Humans; Memory Disorders; Mice; Microglia; Neprilysin; Neural Stem Cells

2023
Wave-Like Dose-Dependence of the Stimulating Effects of Dimebon on Cognition in a Wide Dose Range.
    Bulletin of experimental biology and medicine, 2019, Volume: 167, Issue:6

    Topics: Alzheimer Disease; Animals; Aziridines; Biological Clocks; Central Nervous System Stimulants; Choline; Cognition; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Maze Learning; Mice; Mice, Inbred C57BL; Pattern Recognition, Physiological; Rats; Rats, Wistar

2019
A silk peptide fraction restores cognitive function in AF64A-induced Alzheimer disease model rats by increasing expression of choline acetyltransferase gene.
    Toxicology and applied pharmacology, 2017, Jan-01, Volume: 314

    Topics: Alzheimer Disease; Animals; Avoidance Learning; Aziridines; Cell Line, Tumor; Choline; Choline O-Acetyltransferase; Cognition; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Insect Proteins; Male; Maze Learning; Peptide Fragments; Rats; Rats, Sprague-Dawley; Silk

2017
Role of NAD(P)H:quinone oxidoreductase in the progression of neuronal cell death in vitro and following cerebral ischaemia in vivo.
    Journal of neurochemistry, 2003, Volume: 84, Issue:5

    Topics: Animals; Apoptosis; Aziridines; Brain Ischemia; Cells, Cultured; Choline; Dicumarol; Disease Models, Animal; Disease Progression; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Hydroquinones; Male; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Neurons; Rats; Rats, Wistar

2003
Protection against inflammatory neurodegeneration and glial cell death by 7beta-hydroxy epiandrosterone, a novel neurosteroid.
    Neurobiology of disease, 2004, Volume: 15, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aziridines; Cell Death; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Dehydroepiandrosterone; Disease Models, Animal; Encephalitis; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Immunohistochemistry; Male; Nerve Degeneration; Neuroglia; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Inbred F344; Septal Nuclei; tau Proteins

2004
Glycosaminoglycan C3 protects against AF64A-induced cholinotoxicity in a dose-dependent and time-dependent manner.
    Brain research, 2004, Jul-23, Volume: 1015, Issue:1-2

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Aziridines; Cell Death; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Glycosaminoglycans; Heparinoids; Hippocampus; Male; Neuroprotective Agents; Neurotoxins; Rats; Rats, Inbred F344

2004
FTY720 ameliorates Th1-mediated colitis in mice by directly affecting the functional activity of CD4+CD25+ regulatory T cells.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Feb-15, Volume: 178, Issue:4

    Topics: Animals; Antigens, CD; Antigens, Differentiation; Aziridines; Cell Differentiation; Choline; Colitis; CTLA-4 Antigen; Cytokines; Disease Models, Animal; Down-Regulation; Fingolimod Hydrochloride; Forkhead Transcription Factors; Immunosuppressive Agents; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Neuromuscular Blocking Agents; Propylene Glycols; Sphingosine; T-Lymphocytes, Regulatory; Th1 Cells

2007
The role of the nucleus basalis of Meynert and reticular thalamic nucleus in pathogenesis of genetically determined absence epilepsy in rats: a lesion study.
    Brain research, 2007, Dec-14, Volume: 1185

    Topics: Animals; Antibodies, Monoclonal; Aziridines; Basal Nucleus of Meynert; Behavior, Animal; Choline; Choline O-Acetyltransferase; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Functional Laterality; Male; Rats; Rats, Inbred Strains; Ribosome Inactivating Proteins, Type 1; Saporins; Thalamic Nuclei

2007
Differential expression of inflammatory and fibrogenic genes and their regulation by NF-kappaB inhibition in a mouse model of chronic colitis.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Nov-15, Volume: 179, Issue:10

    Topics: Animals; Aziridines; CD4-Positive T-Lymphocytes; Choline; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Disease Models, Animal; Extracellular Matrix; Female; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Inflammation; Macrophages; Mice; Neuromuscular Blocking Agents; Neutrophil Infiltration; Neutrophils; Oligodeoxyribonucleotides, Antisense; Oligonucleotide Array Sequence Analysis; Time Factors; Transcription Factor RelA

2007
MKC-231, a choline-uptake enhancer: (1) long-lasting cognitive improvement after repeated administration in AF64A-treated rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2008, Volume: 115, Issue:7

    Topics: Animals; Aziridines; Behavior, Animal; Brain; Carbon Isotopes; Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hippocampus; Learning Disabilities; Male; Maze Learning; Quinolines; Rats; Rats, Wistar; Synaptosomes; Time Factors

2008
Lesion with the neurotoxin AF64A alters hippocampal cholinergic receptor function.
    Brain research bulletin, 1995, Volume: 38, Issue:2

    Topics: Acetylcholine; Alzheimer Disease; Animals; Aziridines; Choline; Disease Models, Animal; Electric Stimulation; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Male; Neurotoxins; Nicotine; Oxotremorine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Stimulation, Chemical

1995
Age-dependent effect of AF64A on cholinergic activity in the septo-hippocampal pathway of the rat brain: decreased responsiveness in aged rats.
    Neuroscience letters, 1996, Jan-19, Volume: 203, Issue:2

    Topics: Acetylcholinesterase; Aging; Alzheimer Disease; Animals; Aziridines; Choline; Choline O-Acetyltransferase; Cholinergic Antagonists; Cholinergic Fibers; Disease Models, Animal; Enzyme Induction; Hippocampus; Injections, Intraventricular; Male; Nerve Tissue Proteins; Rats; Rats, Sprague-Dawley; Septum Pellucidum

1996
Arecoline via miniosmotic pump improves AF64A-impaired radial maze performance in rats: a possible model of Alzheimer's disease.
    Neurobiology of learning and memory, 1997, Volume: 68, Issue:3

    Topics: Alzheimer Disease; Animals; Arecoline; Aziridines; Brain; Brain Mapping; Cerebral Cortex; Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Hippocampus; Infusion Pumps, Implantable; Male; Maze Learning; Mental Recall; Muscarinic Agonists; Neurotoxins; Rats; Rats, Sprague-Dawley; Retention, Psychology

1997
Cholinergic influence on vestibular stimulation-induced locus coeruleus inhibition in rats.
    Acta oto-laryngologica, 2000, Volume: 120, Issue:3

    Topics: Animals; Aziridines; Caloric Tests; Choline; Cholinergic Fibers; Disease Models, Animal; Electrodes, Implanted; Locus Coeruleus; Male; Motion Sickness; Muscarinic Antagonists; Neuromuscular Blocking Agents; Rats; Rats, Sprague-Dawley; Scopolamine; Time Factors; Vestibule, Labyrinth

2000
Dimebon improves learning in animals with experimental Alzheimer's disease.
    Bulletin of experimental biology and medicine, 2000, Volume: 129, Issue:6

    Topics: Alzheimer Disease; Animals; Avoidance Learning; Aziridines; Choline; Cholinesterase Inhibitors; Disease Models, Animal; Histamine H1 Antagonists; Indoles; Injections, Intraventricular; Male; Neuromuscular Blocking Agents; Rats; Rats, Wistar; Tacrine

2000
Intracortical AF64A: memory impairments and recovery from cholinergic hypofunction.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4

    Topics: Acetylcholine; Alzheimer Disease; Animals; Avoidance Learning; Aziridines; Biological Transport; Cerebral Cortex; Choline; Disease Models, Animal; Memory; Rats; Rats, Inbred Strains; Time Factors

1989
(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3') quinuclidine (AF102B): a new M1 agonist attenuates cognitive dysfunctions in AF64A-treated rats.
    Neuroscience letters, 1989, Jul-31, Volume: 102, Issue:2-3

    Topics: Alzheimer Disease; Animals; Aziridines; Behavior, Animal; Choline; Cognition Disorders; Disease Models, Animal; Drug Design; Male; Molecular Structure; Parasympathomimetics; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thiophenes

1989
Effects of intracerebroventricular injection of AF64A on learning behaviors in rats.
    Japanese journal of pharmacology, 1988, Volume: 48, Issue:1

    Topics: Alzheimer Disease; Amnesia; Animals; Avoidance Learning; Aziridines; Azirines; Choline; Choline O-Acetyltransferase; Disease Models, Animal; Hippocampus; Injections, Intraventricular; Learning; Male; Physostigmine; Rats; Rats, Inbred Strains

1988
Neurochemical effects following AF64A injection into the basal nuclei of rats.
    The Japanese journal of psychiatry and neurology, 1987, Volume: 41, Issue:4

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Aziridines; Azirines; Basal Ganglia; Choline; Choline O-Acetyltransferase; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Neural Pathways; Neuromuscular Blocking Agents; Rats; Rats, Inbred Strains; Septal Nuclei; Substantia Innominata

1987
Ethylcholine mustard aziridinium ion lesions of the rat cortex result in retrograde degeneration of basal forebrain cholinergic neurons: implications for animal models of neurodegenerative disease.
    Neurochemical research, 1987, Volume: 12, Issue:7

    Topics: Alzheimer Disease; Animals; Aziridines; Azirines; Basal Ganglia; Cerebral Cortex; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Disease Models, Animal; Male; Nerve Degeneration; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Retrograde Degeneration; Substantia Innominata

1987
Immunohistochemical evidence for degeneration of cholinergic neurons in the forebrain of the rat following injection of AF64A-picrylsulfonate into the dorsal hippocampus.
    Brain research, 1986, Apr-02, Volume: 370, Issue:1

    Topics: Alzheimer Disease; Animals; Aziridines; Azirines; Choline; Choline O-Acetyltransferase; Cholinergic Fibers; Diencephalon; Disease Models, Animal; Hippocampus; Rats; Rats, Inbred Strains; Serotonin; Telencephalon; Trinitrobenzenesulfonic Acid

1986
Intracerebral injections of AF64A: an animal model of Alzheimer's disease?
    Annals of the New York Academy of Sciences, 1985, Volume: 444

    Topics: Alzheimer Disease; Animals; Aziridines; Azirines; Brain; Choline; Cholinergic Fibers; Disease Models, Animal; Humans; Injections, Intraventricular; Mental Recall; Neuromuscular Blocking Agents; Rats

1985
Neurochemistry of aging. 1. Toxins for an animal model of Alzheimer's disease.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:3

    Topics: Alzheimer Disease; Animals; Aziridines; Azirines; Binding, Competitive; Biological Transport; Brain Chemistry; Choline; Disease Models, Animal; In Vitro Techniques; Mice; Models, Molecular; Parasympathetic Nervous System; Quinuclidinyl Benzilate; Receptors, Muscarinic; Structure-Activity Relationship; Synaptosomes; Toxins, Biological

1986