Page last updated: 2024-08-21

ethyl pyruvate and Injury, Ischemia-Reperfusion

ethyl pyruvate has been researched along with Injury, Ischemia-Reperfusion in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (34.38)29.6817
2010's19 (59.38)24.3611
2020's2 (6.25)2.80

Authors

AuthorsStudies
Aliyazicioglu, Y; Arslan, A; Demir, S; Kazaz, IO; Kerimoglu, G; Mentese, A; Teoman, AS; Yaman, SO1
Chen, M; Liang, Z; Liu, Y; Lu, C; Wang, C; Wang, H; Wang, Q; Xiao, H; Yang, Y; Yang, Z1
Bai, H; He, Y; Li, W; Lou, J; Wei, L; Zhang, Y1
Choi, N; Jun, JH; Kwak, YL; Shim, JK; Shin, EJ; Song, JW1
Mennander, AA1
Cuzdan, SS; Kayiran, O; Kocer, U; Uysal, A1
Fan, ZX; Li, Q; Yang, J; Yang, Y1
Bloom, J; Choudhury, M; Eshghi, M; Konno, S; Patel, N; Wagmaister, J1
Chen, K; Cheng, P; Dai, W; Guo, C; He, L; Lu, J; Shen, M; Wang, C; Wang, F; Wu, D; Xu, L; Yang, J; Zhang, H; Zhang, Y; Zhou, Y; Zhu, R1
Altun, G; Civelek, A; Hemşinli, D; Menteşe, A; Pulathan, Z; Yuluğ, E1
Caglayan, EK; Caglayan, K; Cinar, H; Göcmen, AY; Güngör, B; Polat, MF; Seckin, L; Seckin, S1
Ahmet, M; Ari, NS; Asli, M; Aynur, S; Esin, Y; Ozgur, T; Selim, D; Suha, T; Süleyman, T; Yunus, K1
Beyhun, E; Cekic Gonenc, O; Demir, S; Gunduz, A; Karaca, Y; Mentese, A; Sahin, A; Turedi, S; Turkmen, S; Yulug, E1
Albadawi, H; Cambria, RP; Crawford, RS; Fink, MP; Nguyen, BN; Oklu, R; Watkins, MT1
Ding, X; Jiang, J; Liu, Y; Su, Q; Zhou, C1
Guo, J; Ji, Y; Jiang, X; Zhang, K; Zuo, S1
Ling, Y; Tao, J; Wang, CY; Wu, HS; Xiong, JX; Yang, ZY; Yin, T1
Chung, KY; Kim, YS; Park, JJ1
Kitano, T; Kuroki, C; Nisimaru, N; Ogata, K; Sakamoto, T; Takei, H; Tokumaru, O; Yokoi, I; Yoshimura, N1
Bilgihan, A; Canbay, E; Cengiz, O; Dolapci, M; Eroglu, A; Huner, T; Karabeyoglu, M; Unal, B; Yildirim, O1
Chen, S; Ding, Q; Gou, X; Hou, L; Wang, Q; Xiong, L; Zhou, Y; Zhu, Z1
Cruz, RJ; Fink, MP; Harada, T; Sasatomi, E1
Chung, YK; Jang, IS; Lee, HK; Park, MY; Shin, IW; Sohn, JT1
Chen, Q; Chen, Y; Dai, HL; Lv, LX; Qian, JQ; Xu, XH; Zhu, CQ1
Albadawi, H; Atkins, MD; Austen, WG; Conrad, MF; Crawford, RS; Fink, MP; Jones, JJ; Watkins, MT1
Karaca, Y; Karaguzel, E; Kucuk, A; Mentese, A; Turedi, S; Turkmen, S; Uzun, A; Yulug, E1
Ghaly, T; Goligorksy, MS; Rabadi, MM; Ratliff, BB1
Delude, RL; Fink, MP; Uchiyama, T1
Bucher, B; Fink, MP; Geller, DA; Kaizu, T; Murase, N; Nakao, A; Shao, L; Tsung, A1
Bilgihan, A; Bozkurt, B; Cengiz, O; Dolapçi, I; Karabeyoğlu, I; Karabeyoğlu, M; Unal, B1
Fink, MP1
Ajami, AM; Fink, MP; Menconi, MJ; Sims, CA; Wattanasirichaigoon, S1

Reviews

2 review(s) available for ethyl pyruvate and Injury, Ischemia-Reperfusion

ArticleYear
Ethyl pyruvate: A newly discovered compound against ischemia-reperfusion injury in multiple organs.
    Pharmacological research, 2021, Volume: 171

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Humans; Pyruvates; Reperfusion Injury

2021
Ethyl pyruvate.
    Current opinion in anaesthesiology, 2008, Volume: 21, Issue:2

    Topics: Anti-Inflammatory Agents; Humans; Neuroprotective Agents; Pancreatitis; Pyruvates; Reperfusion Injury; Sepsis; Shock, Hemorrhagic; Shock, Septic

2008

Other Studies

30 other study(ies) available for ethyl pyruvate and Injury, Ischemia-Reperfusion

ArticleYear
Effect of ethyl pyruvate on oxidative state and endoplasmic reticulum stress in a rat model of testicular torsion.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2020, Volume: 95, Issue:4

    Topics: Animals; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation; Heat-Shock Proteins; Male; Oxidative Stress; Pyruvates; Random Allocation; Rats; Reperfusion Injury; Spermatic Cord Torsion; Testis

2020
Ethyl pyruvate protects PC12 cells from oxygen-glucose deprivation: A potential role in ischemic cerebrovascular disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Animals; Apoptosis; Behavior, Animal; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cell Survival; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Injections, Intravenous; Male; Nerve Growth Factor; Nerve Tissue Proteins; Nestin; Neurons; Neuroprotective Agents; Pyruvates; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Specific Pathogen-Free Organisms

2017
Ethyl pyruvate is renoprotective against ischemia-reperfusion injury under hyperglycemia.
    The Journal of thoracic and cardiovascular surgery, 2018, Volume: 155, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Cytoprotection; Disease Models, Animal; HMGB1 Protein; Hyperglycemia; Interleukin-1beta; Kidney; Kidney Diseases; Male; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Pyruvates; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Toll-Like Receptors; Tumor Necrosis Factor-alpha

2018
Time to celebrate!
    The Journal of thoracic and cardiovascular surgery, 2018, Volume: 155, Issue:4

    Topics: Humans; Hyperglycemia; Pyruvates; Reperfusion Injury

2018
Ethyl pyruvate improves skin flap survival after ischaemia reperfusion injury.
    The Indian journal of medical research, 2017, Volume: 146, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Humans; Malondialdehyde; Oxidative Stress; Peroxidase; Pyruvates; Rats; Reperfusion Injury; Skin; Surgical Flaps

2017
Ethyl pyruvate: A promising feasible therapeutic approach for myocardial ischemia-reperfusion injury under both normoglycemia and hyperglycemia.
    International journal of cardiology, 2018, 08-15, Volume: 265

    Topics: Humans; Hyperglycemia; Myocardial Reperfusion Injury; Pyruvates; Reperfusion Injury

2018
Prophylactic effect of ethyl pyruvate on renal ischemia/reperfusion injury mediated through oxidative stress.
    International urology and nephrology, 2019, Volume: 51, Issue:1

    Topics: Antioxidants; Cell Survival; Cells, Cultured; Epithelial Cells; Humans; Hydrogen Peroxide; Kidney Tubules, Proximal; Lipid Peroxidation; Oxidative Stress; Protective Agents; Pyruvates; Reperfusion Injury

2019
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagy.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; bcl-2-Associated X Protein; Beclin-1; HMGB1 Protein; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Pyruvates; Reperfusion Injury; Tumor Necrosis Factor-alpha

2013
Role of ethyl pyruvate in systemic inflammatory response and lung injury in an experimental model of ruptured abdominal aortic aneurysm.
    BioMed research international, 2014, Volume: 2014

    Topics: Aneurysm, Ruptured; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Humans; Lung Injury; Male; Pyruvates; Rats; Reperfusion Injury; Systemic Inflammatory Response Syndrome

2014
Protective effect of ethyl pyruvate on ischemia-reperfusion injury in rat ovary: biochemical and histopathological evaluation.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 182

    Topics: Animals; Antioxidants; Arginine; Disease Models, Animal; Female; Malondialdehyde; Ovary; Pyruvates; Rats; Rats, Wistar; Reperfusion Injury; Torsion Abnormality

2014
Effects of N-acetylcysteine and ethyl pyruvate on ischemia-reperfusion injury in experimental electrical burn model.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:7

    Topics: Acetylcysteine; Animals; Burns, Electric; Disease Models, Animal; Female; Free Radical Scavengers; Male; Pyruvates; Rats; Rats, Wistar; Reperfusion Injury

2016
The effect of ethyl pyruvate and N-acetylcysteine on ischemia-reperfusion injury in an experimental model of ischemic stroke.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:9

    Topics: Acetylcysteine; Animals; Brain; Brain Ischemia; Carotid Arteries; Cell Count; Female; Free Radical Scavengers; Neurons; Pyruvates; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke

2016
Ethyl pyruvate modulates delayed paralysis following thoracic aortic ischemia reperfusion in mice.
    Journal of vascular surgery, 2016, Volume: 64, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Aorta, Thoracic; Apoptosis; Apoptosis Regulatory Proteins; Constriction; Disease Models, Animal; Inflammation; Inflammation Mediators; Male; Mice, Inbred C57BL; Neuroprotective Agents; Paralysis; Pyruvates; Regional Blood Flow; Reperfusion Injury; Signal Transduction; Spinal Cord; Spinal Cord Ischemia; Time Factors

2016
Blockade of HMGB1 preserves vascular homeostasis and improves blood perfusion in rats of acute limb ischemia/reperfusion.
    Microvascular research, 2017, Volume: 112

    Topics: Actins; Animals; Anti-Inflammatory Agents; Blood Flow Velocity; Disease Models, Animal; Hemorheology; Heparin; Hindlimb; HMGB1 Protein; Inflammation Mediators; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Skeletal; Pyruvates; Rats, Wistar; Recovery of Function; Regional Blood Flow; Reperfusion Injury; Signal Transduction; Vascular Remodeling

2017
Effects of ethyl pyruvate on myocardial apoptosis and expression of Bcl-2 and Bax proteins after ischemia-reperfusion in rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2008, Volume: 28, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; In Situ Nick-End Labeling; Male; Malondialdehyde; Myocardium; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Pyruvates; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tissue Distribution

2008
Delayed ethyl pyruvate therapy attenuates experimental severe acute pancreatitis via reduced serum high mobility group box 1 levels in rats.
    World journal of gastroenterology, 2008, Jul-28, Volume: 14, Issue:28

    Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Creatinine; Disease Models, Animal; HMGB1 Protein; Kaplan-Meier Estimate; Kidney; Liver; Lung; Male; Pancreatitis; Pyruvates; Rats; Rats, Wistar; Reperfusion Injury; Severity of Illness Index; Tumor Necrosis Factor-alpha

2008
The role of high-mobility group box-1 in renal ischemia and reperfusion injury and the effect of ethyl pyruvate.
    Transplantation proceedings, 2008, Volume: 40, Issue:7

    Topics: Animals; Creatinine; HMGB1 Protein; Ischemia; Pyruvates; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Tumor Necrosis Factor-alpha

2008
Neuroprotective effects of ethyl pyruvate on brain energy metabolism after ischemia-reperfusion injury: a 31P-nuclear magnetic resonance study.
    Neurochemical research, 2009, Volume: 34, Issue:4

    Topics: Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Electron Spin Resonance Spectroscopy; Energy Metabolism; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Magnetic Resonance Spectroscopy; Male; Neuroprotective Agents; Phosphocreatine; Pyruvates; Rats; Reperfusion Injury

2009
Ethyl pyruvate protects colonic anastomosis from ischemia-reperfusion injury.
    Surgical innovation, 2009, Volume: 16, Issue:1

    Topics: Anastomosis, Surgical; Animals; Dose-Response Relationship, Drug; Male; Pyruvates; Rats; Rats, Wistar; Reperfusion Injury; Wound Healing

2009
Ethyl pyruvate attenuates spinal cord ischemic injury with a wide therapeutic window through inhibiting high-mobility group box 1 release in rabbits.
    Anesthesiology, 2009, Volume: 110, Issue:6

    Topics: Animals; Apoptosis; Blood Gas Analysis; Blood Glucose; Body Temperature; Coloring Agents; Enzyme-Linked Immunosorbent Assay; Hemodynamics; High Mobility Group Proteins; Hindlimb; In Situ Nick-End Labeling; Male; Pyruvates; Rabbits; Reperfusion Injury; Repressor Proteins; Spinal Cord Ischemia

2009
Effects of ethyl pyruvate and other α-keto carboxylic acid derivatives in a rat model of multivisceral ischemia and reperfusion.
    The Journal of surgical research, 2011, Volume: 165, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Cytoprotection; Disease Models, Animal; Fluid Therapy; Glyoxylates; Intestinal Mucosa; Ischemia; Lipid Peroxidation; Liver; Male; Mandelic Acids; Permeability; Phenylpyruvic Acids; Pyruvates; Rats; Reperfusion Injury; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2011
Ethyl pyruvate has anti-inflammatory and delayed myocardial protective effects after regional ischemia/reperfusion injury.
    Yonsei medical journal, 2010, Volume: 51, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Cell Nucleus; Cytoplasm; Heart; Inflammation; Male; Myocardial Infarction; Myocardium; NF-kappa B; Peroxidase; Pyruvates; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2010
[Effect of ethyl pyruvate on expression of inflammatory factors and mitogen-activated protein kinase proteins in renal ischemic/reperfusion injury in BABL/c mice].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2010, Volume: 22, Issue:12

    Topics: Animals; HMGB1 Protein; Intercellular Adhesion Molecule-1; Interleukin-6; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Pyruvates; Reperfusion Injury; Tumor Necrosis Factor-alpha

2010
Postischemic treatment with ethyl pyruvate prevents adenosine triphosphate depletion, ameliorates inflammation, and decreases thrombosis in a murine model of hind-limb ischemia and reperfusion.
    The Journal of trauma, 2011, Volume: 70, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antithrombin III; Disease Models, Animal; Inflammation; Interleukin-1; Lactates; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Peptide Hydrolases; Peroxidase; Pyruvates; Reperfusion Injury; Thrombosis

2011
A comparison of the effects of N-acetylcysteine and ethyl pyruvate on experimental testicular ischemia-reperfusion injury.
    Fertility and sterility, 2012, Volume: 98, Issue:3

    Topics: Acetylcysteine; Animals; Male; Malondialdehyde; Peroxidase; Pyruvates; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Serum Albumin; Testis

2012
HMGB1 in renal ischemic injury.
    American journal of physiology. Renal physiology, 2012, Sep-15, Volume: 303, Issue:6

    Topics: Animals; Bone Marrow Cells; Creatinine; Cytokines; High Mobility Group Proteins; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Kidney; Male; Mice; Oxidative Stress; Pyruvates; Reperfusion Injury; Repressor Proteins

2012
Dose-dependent effects of ethyl pyruvate in mice subjected to mesenteric ischemia and reperfusion.
    Intensive care medicine, 2003, Volume: 29, Issue:11

    Topics: Analysis of Variance; Animals; Blood Pressure; Capillary Permeability; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Free Radical Scavengers; Ileum; Intestinal Mucosa; Ischemia; Laser-Doppler Flowmetry; Liver; Male; Mesenteric Vascular Occlusion; Mesentery; Mice; Mice, Inbred C57BL; NF-kappa B; Pyruvates; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha

2003
Ethyl pyruvate ameliorates liver ischemia-reperfusion injury by decreasing hepatic necrosis and apoptosis.
    Transplantation, 2005, Jan-27, Volume: 79, Issue:2

    Topics: Animals; Apoptosis; Cytokines; Lipid Peroxidation; Liver; Liver Circulation; Liver Function Tests; Male; Necrosis; Neutrophils; Pyruvates; Rats; Rats, Inbred Lew; Reperfusion Injury

2005
The effect of ethyl pyruvate on oxidative stress in intestine and bacterial translocation after thermal injury.
    The Journal of surgical research, 2008, Volume: 144, Issue:1

    Topics: Animals; Bacterial Translocation; Burns; Intestinal Mucosa; Intestines; Liver; Lymph Nodes; Malondialdehyde; Oxidative Stress; Peroxidase; Pyruvates; Rats; Rats, Wistar; Reperfusion Injury; Spleen

2008
Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats.
    Critical care medicine, 2001, Volume: 29, Issue:8

    Topics: Animals; Intestinal Mucosa; Intestine, Small; Ischemia; Male; Mutagens; Pyruvates; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2001