Page last updated: 2024-08-21

ethyl pyruvate and Blood Poisoning

ethyl pyruvate has been researched along with Blood Poisoning in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (68.00)29.6817
2010's7 (28.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Chu, C; Ding, W; Duan, Z; Li, J; Li, W; Liu, B; Sun, S; Wang, K; Wang, X; Yang, C1
Chen, LW; Chen, W; Hong, GL; Lian, J; Lu, ZQ; Mo, QF; Qin, J; Ye, JJ; Zhao, GJ; Zhi, SC1
Breithaupt-Faloppa, AC; Correia, CJ; Ferreira, SG; Guarda, IF; Martinez, MB; Moreno, AC; Rocha-e-Silva, M; Sannomiya, P1
Chen, J; Chen, M; Guan, X; Jiang, Z; Li, X; Lin, Z1
Ding, G; Gao, YH; Pan, SM; Wang, HR; Xu, WP; Zheng, YJ1
Huang, J; Li, S; Li, X; Li, Y; Mu, D; Qu, Y; Zhao, F; Zhu, T1
Li, M; Meng, M; Qin, C; Zhang, Y1
Barochia, A; Cui, X; Eichacker, PQ; Li, X; Li, Y; Su, J1
Deng, ZH; Lin, J; Ti, DD; Wang, LH; Xue, H; Yan, GT1
Cai, B; Deitch, EA; Ulloa, L1
Akalin, B; Altun, H; Aydin, MT; Ekci, B; Karip, AB; Memisoglu, K; Onur, E1
Czura, CJ; Fink, MP; Halperin, D; Ochani, M; Tanovic, M; Tracey, KJ; Ulloa, L; Yang, H; Yang, R1
Hewitt, SM; Hu, X; Iyer, S; Miyaji, T; Muramatsu, Y; Star, RA; Yuen, PS1
Fink, MP5
Han, PL; Kim, JB; Kim, SY; Lee, JK; Lee, KW; Yu, YM1
Das, UN2
Lever, A; Mackenzie, I1
Cui, X; Eichacker, PQ; Fitz, Y; Hsu, L; Li, X; Li, Y; Mani, H; Quezado, M; Su, J1
Tenhunen, JJ1
Dellinger, RP; Nahra, R1

Reviews

11 review(s) available for ethyl pyruvate and Blood Poisoning

ArticleYear
Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate.
    Expert opinion on investigational drugs, 2009, Volume: 18, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Humans; Mice; NF-kappa B; Pyruvates; Sepsis; Sesquiterpenes

2009
Novel insights for systemic inflammation in sepsis and hemorrhage.
    Mediators of inflammation, 2010, Volume: 2010

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Choline; Cytokines; Disease Models, Animal; Hemorrhage; HMGB1 Protein; Humans; Inflammation; Nicotinic Agonists; Nootropic Agents; Pyruvates; Receptors, Nicotinic; Sepsis

2010
Ethyl pyruvate: a novel treatment for sepsis and shock.
    Minerva anestesiologica, 2004, Volume: 70, Issue:5

    Topics: Humans; Pyruvates; Sepsis; Shock, Septic

2004
Pyruvate is an endogenous anti-inflammatory and anti-oxidant molecule.
    Medical science monitor : international medical journal of experimental and clinical research, 2006, Volume: 12, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cytokines; Free Radicals; Glucose; Humans; Insulin; Macrophage Migration-Inhibitory Factors; Pyruvates; Pyruvic Acid; Sepsis; Tumor Necrosis Factor-alpha

2006
Is pyruvate an endogenous anti-inflammatory molecule?
    Nutrition (Burbank, Los Angeles County, Calif.), 2006, Volume: 22, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Critical Illness; Cytokines; Disease Models, Animal; Free Radical Scavengers; Humans; Insulin; Macrophage Migration-Inhibitory Factors; Myocardial Infarction; NF-kappa B; Pyruvates; Pyruvic Acid; Sepsis; Signal Transduction

2006
Ethyl pyruvate: a novel treatment for sepsis.
    Novartis Foundation symposium, 2007, Volume: 280

    Topics: Animals; Humans; Pyruvates; Sepsis

2007
Ethyl pyruvate: a novel treatment for sepsis.
    Current drug targets, 2007, Volume: 8, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Humans; Mice; Pyruvates; Sepsis

2007
Management of sepsis.
    BMJ (Clinical research ed.), 2007, Nov-03, Volume: 335, Issue:7626

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; HMGB1 Protein; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoglobulins; Multiple Organ Failure; Nicotinic Agonists; Prognosis; Pyruvates; Sepsis

2007
Targeting the lipopolysaccharides: still a matter of debate?
    Current opinion in anaesthesiology, 2008, Volume: 21, Issue:2

    Topics: Antibodies, Bacterial; Antimicrobial Cationic Peptides; Bacterial Vaccines; Cathelicidins; Curcumin; Emulsions; Endotoxemia; Endotoxins; Humans; Incidence; Lipopolysaccharides; Phospholipids; Pyruvates; Sepsis

2008
Ethyl pyruvate.
    Current opinion in anaesthesiology, 2008, Volume: 21, Issue:2

    Topics: Anti-Inflammatory Agents; Humans; Neuroprotective Agents; Pancreatitis; Pyruvates; Reperfusion Injury; Sepsis; Shock, Hemorrhagic; Shock, Septic

2008
Reactive oxygen species as mediators of organ dysfunction caused by sepsis, acute respiratory distress syndrome, or hemorrhagic shock: potential benefits of resuscitation with Ringer's ethyl pyruvate solution.
    Current opinion in clinical nutrition and metabolic care, 2002, Volume: 5, Issue:2

    Topics: Adult; Animals; Critical Care; Disease Models, Animal; Humans; Isotonic Solutions; Multiple Organ Failure; NF-kappa B; Pyruvates; Reactive Oxygen Species; Respiratory Distress Syndrome; Resuscitation; Sepsis; Shock, Hemorrhagic

2002

Other Studies

14 other study(ies) available for ethyl pyruvate and Blood Poisoning

ArticleYear
Protective effect of ethyl pyruvate on gut barrier function through regulations of ROS-related NETs formation during sepsis.
    Molecular immunology, 2021, Volume: 132

    Topics: Animals; Extracellular Traps; Hydrogen Peroxide; Intestine, Small; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Protective Agents; Pyruvates; Reactive Oxygen Species; Sepsis

2021
Ethyl pyruvate reverses development of Pseudomonas aeruginosa pneumonia during sepsis-induced immunosuppression.
    International immunopharmacology, 2017, Volume: 52

    Topics: Animals; Apoptosis; Bacterial Load; Cecum; Cytokines; Disease Models, Animal; HMGB1 Protein; Immunity, Innate; Immunosuppression Therapy; Interleukin-10; Lung; Male; Mice; Mice, Inbred BALB C; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Pyruvates; Sepsis; Spleen

2017
Effects of ethyl pyruvate on leukocyte-endothelial interactions in the mesenteric microcirculation during early sepsis treatment.
    Clinics (Sao Paulo, Brazil), 2015, Volume: 70, Issue:7

    Topics: Animals; Cell Communication; Disease Models, Animal; Endothelial Cells; Escherichia coli Infections; Leukocytes; Male; Mesenteric Veins; Microcirculation; Pyruvates; Rats; Rats, Wistar; Sepsis

2015
Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:7

    Topics: Animals; Aquaporins; Benzimidazoles; Carbocyanines; Disease Models, Animal; Humans; Liver; Liver Diseases; Male; Mitochondria, Liver; Mitochondrial Swelling; Pyruvates; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis

2015
Expression of HMGB1 in septic serum induces vascular endothelial hyperpermeability.
    Molecular medicine reports, 2016, Volume: 13, Issue:1

    Topics: Actins; Antigens, CD; Apoptosis; bcl-2-Associated X Protein; Cadherins; Capillary Permeability; Cytoskeleton; Endothelium, Vascular; Female; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Male; Middle Aged; Pyruvates; Sepsis

2016
Role of HMGB1 translocation to neuronal nucleus in rat model with septic brain injury.
    Neuroscience letters, 2017, 04-03, Volume: 645

    Topics: Active Transport, Cell Nucleus; Animals; Brain Injuries; Cell Count; Cell Nucleus; Cerebral Cortex; HMGB1 Protein; Male; Neurons; Neuroprotective Agents; Pyruvates; Rats, Wistar; Receptor for Advanced Glycation End Products; Sepsis; Transcription Factor RelA

2017
Effect of ethyl pyruvate on physical and immunological barriers of the small intestine in a rat model of sepsis.
    The Journal of trauma, 2009, Volume: 66, Issue:5

    Topics: Analysis of Variance; Animals; Bacterial Translocation; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunohistochemistry; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Kaplan-Meier Estimate; Male; Probability; Pyruvates; Random Allocation; Rats; Rats, Wistar; Sepsis; Survival Analysis

2009
[Effects of ethyl pyruvate on injuries of sepsis in mice].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2009, Volume: 21, Issue:8

    Topics: Alkaline Phosphatase; Animals; Disease Models, Animal; Intestines; Lactic Acid; Lung; Male; Mice; Pyruvates; Pyruvic Acid; Sepsis; Uric Acid

2009
Ethyl pyruvate improves healing of colonic anastomosis in a rat model of peritonitis.
    Surgical innovation, 2012, Volume: 19, Issue:4

    Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Colon; Disease Models, Animal; Hydroxyproline; Male; Peritonitis; Pressure; Pyruvates; Rats; Rats, Wistar; Sepsis; Wound Healing

2012
Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Sep-17, Volume: 99, Issue:19

    Topics: Animals; Cell Line; Endotoxemia; Enzyme Activation; HMGB1 Protein; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyruvates; RNA, Messenger; Sepsis; Signal Transduction; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha

2002
Ethyl pyruvate decreases sepsis-induced acute renal failure and multiple organ damage in aged mice.
    Kidney international, 2003, Volume: 64, Issue:5

    Topics: Acute Kidney Injury; Aging; Animals; Anti-Bacterial Agents; Blood Coagulation; Cecum; Cysteine-Rich Protein 61; Disease Models, Animal; Fibrinolysis; Fluid Therapy; Gene Expression; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney Tubules; Ligation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Pyruvates; RNA, Messenger; Sepsis; Tumor Necrosis Factor-alpha; Wounds, Stab

2003
Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: Animals; Brain; Brain Injuries; Brain Ischemia; Coloring Agents; Cytokines; Dose-Response Relationship, Drug; Immunoblotting; Immunohistochemistry; Infarction, Middle Cerebral Artery; Inflammation; Ischemia; Lipopolysaccharides; Male; Microglia; Neuroprotective Agents; Neuropsychological Tests; Nitric Oxide; Pyruvates; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sepsis; Tetrazolium Salts; Time Factors

2005
Ethyl pyruvate decreased early nuclear factor-kappaB levels but worsened survival in lipopolysaccharide-challenged mice.
    Critical care medicine, 2008, Volume: 36, Issue:4

    Topics: Animals; Cytokines; Kidney; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; NF-kappa B; Proportional Hazards Models; Pyruvates; Sepsis; Treatment Failure

2008
Bull's eye missed by the magic bullet: preclinical investigations, publication bias, and promising new interventions.
    Critical care medicine, 2008, Volume: 36, Issue:4

    Topics: Animals; Cytokines; Disease Models, Animal; Lipopolysaccharides; Mice; NF-kappa B; Publication Bias; Pyruvates; Sepsis

2008