Page last updated: 2024-08-17

ethyl methanesulfonate and Pregnancy

ethyl methanesulfonate has been researched along with Pregnancy in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199023 (62.16)18.7374
1990's6 (16.22)18.2507
2000's5 (13.51)29.6817
2010's3 (8.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blanche, S; Goujon, S; Hleyhel, M; Sibiude, J; Warszawski, J1
Gocke, E; Müller, L; Pfister, T1
Müller, L; Singer, T1
Barr, DB; Davis, MD; Jayatilaka, NK; Kuklenyik, P; Montesano, MA; Needham, LL; Whitehead, RD1
Donovan, P; Smith, G1
Eckhardt, K; Gocke, E; King, MT; Wild, D1
Himeno, S; Okuda, H; Suzuki, T1
Anderson, D; McGregor, DB; Weight, TM1
Heiderstädt, R; Mendel, J; Schreiber, D1
Bochert, G; Platzek, T; Rahm, U1
Bochert, G; Meister, R; Neubert, D; Platzek, T1
Bochert, G; Meister, R; Platzek, T1
Narasimhamurthy, K1
Bochert, G; Platzek, T2
Dalivelya, O; Goncharova, R; Kuzhir, T; Zabrejko, S1
Lutz, WK; Stopper, H1
Fahrig, R1
Arnold, DW; Calandra, JC; Kennedy, GL; keplinger, ML1
Soares, ER1
Kratochvilova, J2
Heiderstädt, R; Schneider, J; Schreiber, D; Warzok, R1
Crenshaw, JW; Favor, J; Soares, ER1
Fahrig, R; Seiler, JP1
Akatsuka, K; Hashimoto, T; Ohhira, M; Takeuchi, K1
Anderson, D; Hodge, MC; Purchase, IF1
Anderson, D; Cuthbert, JA; Hodge, MC; McGregor, DB; Purchase, IF1
Bishop, JB; Harbison, RD; Teaf, CM2
Brambilla, G; Parodi, A; Robbiano, L; Venturelli, S1
Faustman, EM; Gage, D; Kirby, Z; Varnum, M1
Ficsor, G; Goldner, L; Panda, BB1
Cacheiro, NL; Cain, KT; Cornett, CV; Generoso, WM; Katoh, M; Rutledge, JC1
Bochert, G; Neubert, D; Platzek, T; Rahm, U1
Cain, KT; Downing, DJ; Generoso, WM; Hughes, LA; Rutledge, JC1
Lyon, MF; Renshaw, R1

Reviews

1 review(s) available for ethyl methanesulfonate and Pregnancy

ArticleYear
Embryotoxicity induced by alkylating agents: 7. Low dose prenatal-toxic risk estimation based on NOAEL risk factor approach, dose-response relationships, and DNA adducts using methylnitrosourea as a model compound.
    Teratogenesis, carcinogenesis, and mutagenesis, 1993, Volume: 13, Issue:3

    Topics: Abnormalities, Drug-Induced; Algorithms; Alkylating Agents; Alkylation; Animals; DNA; DNA Damage; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Fetal Death; Guanine; Methylnitrosourea; Mice; Models, Theoretical; Pregnancy; Risk Factors; Toxicology

1993

Other Studies

36 other study(ies) available for ethyl methanesulfonate and Pregnancy

ArticleYear
In-utero exposure to nelfinavir-ethyl methyl sulfone.
    AIDS (London, England), 2016, 11-13, Volume: 30, Issue:17

    Topics: Adolescent; Child; Child, Preschool; Congenital Abnormalities; Drug Contamination; Ethyl Methanesulfonate; Female; Follow-Up Studies; France; HIV Protease Inhibitors; Humans; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Mutagens; Nelfinavir; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies

2016
EMS in Viracept--initial ('traditional') assessment of risk to patients based on linear dose response relations.
    Toxicology letters, 2009, Nov-12, Volume: 190, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents, Alkylating; Carcinogenicity Tests; Dose-Response Relationship, Drug; Drug Contamination; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Germ-Line Mutation; HIV Protease Inhibitors; Humans; Linear Models; Mammary Neoplasms, Animal; Methyl Methanesulfonate; Mice; Mutagenicity Tests; Nelfinavir; No-Observed-Adverse-Effect Level; Pregnancy; Quantitative Structure-Activity Relationship; Rats; Risk Assessment

2009
EMS in Viracept--the course of events in 2007 and 2008 from the non-clinical safety point of view.
    Toxicology letters, 2009, Nov-12, Volume: 190, Issue:3

    Topics: Adult; Animals; Dose-Response Relationship, Drug; Drug and Narcotic Control; Drug Contamination; Drug-Related Side Effects and Adverse Reactions; Ethyl Methanesulfonate; European Union; Female; History, 21st Century; HIV Protease Inhibitors; Humans; Mice; Mutagenicity Tests; Mutagens; Nelfinavir; No-Observed-Adverse-Effect Level; Pregnancy; Product Surveillance, Postmarketing; Rats; Registries; Risk Assessment

2009
Measurement of ethyl methanesulfonate in human plasma and breast milk samples using high-performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2010, Jun-05, Volume: 52, Issue:2

    Topics: Atmospheric Pressure; Calibration; Chromatography, High Pressure Liquid; Ethyl Methanesulfonate; Female; Humans; Limit of Detection; Milk, Human; Molecular Structure; Molecular Weight; Mutagens; Pregnancy; Quality Control; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2010
Mutagenicity of N-ethyl-N-nitrosourea, N-methyl-N-nitrosourea, methyl methanesulfonate and ethyl methanesulfonate in the developing Syrian hamster fetus.
    Mutation research, 2010, Jun-17, Volume: 699, Issue:1-2

    Topics: Animals; Cricetinae; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Fetus; Maternal-Fetal Exchange; Mesocricetus; Methyl Methanesulfonate; Methylnitrosourea; Mutagenicity Tests; Mutagens; Pregnancy; Pregnancy, Animal

2010
Mutagenicity studies with the mouse spot test.
    Mutation research, 1983, Volume: 117, Issue:1-2

    Topics: 2-Acetylaminofluorene; Animals; Colchicine; Embryo, Mammalian; Environmental Pollution; Ethyl Methanesulfonate; Ethylene Dichlorides; Ethylnitrosourea; Female; Mice; Mice, Inbred C57BL; Mutagenicity Tests; Mutagens; Mutation; Pregnancy

1983
Lack of dominant lethal effects in male CD-1 mice after short-term and long-term exposures to vinyl chloride monomer.
    Toxicology letters, 1983, Volume: 16, Issue:1-2

    Topics: Animals; Corpus Luteum; Embryo Implantation; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Male; Mice; Pregnancy; Pregnancy, Animal; Sperm Motility; Spermatogenesis; Vinyl Chloride; Vinyl Compounds

1983
The relationship between early deaths and implants in control and mutagen-treated CD-1 mice in dominant lethal assays.
    Mutation research, 1981, Volume: 81, Issue:2

    Topics: Animals; Cyclophosphamide; Embryo Implantation; Ethyl Methanesulfonate; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Male; Mice; Mutagenicity Tests; Mutagens; Pregnancy; Statistics as Topic

1981
[Structure-activity relationships in experimental neuro-oncology (author's transl)].
    Archiv fur Geschwulstforschung, 1981, Volume: 51, Issue:7

    Topics: Animals; Carcinogens; Ethyl Methanesulfonate; Female; Maternal-Fetal Exchange; Methyl Methanesulfonate; Neoplasms, Experimental; Nervous System Neoplasms; Pregnancy; Rats; Structure-Activity Relationship

1981
Embryotoxicity induced by alkylating agents: 8. DNA adduct formation induced by ethylmethanesulfonate in mouse embryos.
    Teratogenesis, carcinogenesis, and mutagenesis, 1994, Volume: 14, Issue:2

    Topics: Alkylating Agents; Animals; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Gestational Age; Mice; Pregnancy; Teratogens

1994
Embryotoxicity induced by alkylating agents: 9. Low dose prenatal-toxic risk estimation of ethylmethanesulfonate based on no-observed-adverse-effect-level risk factor approach, dose-response relationships, and molecular dosimetry.
    Teratogenesis, carcinogenesis, and mutagenesis, 1995, Volume: 15, Issue:2

    Topics: Alkylating Agents; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Female; Fetal Resorption; Litter Size; Male; Mice; Mice, Inbred Strains; No-Observed-Adverse-Effect Level; Pregnancy; Risk Factors; Teratogens

1995
Incidence of spontaneous post-implantation deaths in CFT-Swiss mice: its suitability to assess dominant lethal mutations.
    Laboratory animals, 1996, Volume: 30, Issue:2

    Topics: Animals; Embryo Implantation; Embryonic and Fetal Development; Embryonic Development; Ethyl Methanesulfonate; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Germ-Line Mutation; Litter Size; Male; Mice; Mutagenicity Tests; Mutagens; Pregnancy

1996
Embryotoxicity induced by alkylating agents: 10. Analysis of the combined teratogenic effects of methylnitrosourea and ethylmethanesulfonate in mice.
    Teratogenesis, carcinogenesis, and mutagenesis, 1995, Volume: 15, Issue:4

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Animals; Bone and Bones; Dose-Response Relationship, Drug; Drug Synergism; Ethyl Methanesulfonate; Female; Methylnitrosourea; Mice; Pregnancy

1995
DNA alkylation studies of combined treatment with methylnitrosourea and ethylmethanesulfonate in mice.
    Teratogenesis, carcinogenesis, and mutagenesis, 2000, Volume: 20, Issue:1

    Topics: Alkylating Agents; Alkylation; Animals; DNA; DNA Damage; DNA Methylation; Drug Synergism; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Guanine; Injections, Intraperitoneal; Liver; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Pregnancy

2000
Anticlastogenicity of two derivatives of 1,4-dihydroisonicotinic acid in mouse micronucleus test.
    Mutation research, 2001, Sep-20, Volume: 496, Issue:1-2

    Topics: Animals; Antimutagenic Agents; Bone Marrow Cells; DNA Damage; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Erythrocytes; Ethyl Methanesulfonate; Female; Isonicotinic Acids; Liver; Male; Maternal Exposure; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Micronucleus Tests; Mutagens; Pregnancy

2001
Induction of micronuclei in human cell lines and primary cells by combination treatment with gamma-radiation and ethyl methanesulfonate.
    Mutagenesis, 2002, Volume: 17, Issue:2

    Topics: Animals; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Female; Fetus; Fibroblasts; Gamma Rays; Humans; Leukemia L5178; Lung; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Mutation; Pregnancy; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
A mammalian spot test: induction of genetic alterations in pigment cells of mouse embryos with x-rays and chemical mutagens.
    Molecular & general genetics : MGG, 1975, Jul-10, Volume: 138, Issue:4

    Topics: Animals; Chromosome Aberrations; Ethyl Methanesulfonate; Female; Genes, Recessive; Male; Maternal-Fetal Exchange; Mesylates; Methyl Methanesulfonate; Mice; Mutation; Pigmentation; Pregnancy; Radiation Genetics; Recombination, Genetic; Time Factors

1975
Dominant lethal studies with alkylating agents: dose-response relationships.
    Toxicology and applied pharmacology, 1976, Volume: 38, Issue:1

    Topics: Alkylating Agents; Animals; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Male; Mesylates; Methyl Methanesulfonate; Mutagens; Pregnancy; Reproduction; Time Factors

1976
Studies of factors influencing the mutagenicity of EMS in mice.
    Mutation research, 1976, Volume: 37, Issue:2-3

    Topics: Administration, Oral; Animals; Crosses, Genetic; Ethyl Methanesulfonate; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Injections; Injections, Intraperitoneal; Male; Mesylates; Mice; Mice, Inbred DBA; Mutation; Pregnancy; Species Specificity; Testis

1976
Evaluation of pre-implantation loss in dominant-lethal assay in the mouse.
    Mutation research, 1978, Volume: 54, Issue:1

    Topics: 1-Propanol; Animals; Crosses, Genetic; Embryonic Development; Ethyl Methanesulfonate; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Genetic Techniques; Male; Mesylates; Mice; Mice, Inbred Strains; Pregnancy; Pregnancy, Animal; Spermatids; Spermatozoa

1978
[Postnatal and transplacental carcinogenic effects of methyl methanesulphonate (MMS) and ethyl methanesulphonate (EMS) in hooded rats (author's transl)].
    Experimentelle Pathologie, 1978, Volume: 16, Issue:1-6

    Topics: Age Factors; Animals; Animals, Newborn; Ethyl Methanesulfonate; Female; Mesylates; Methyl Methanesulfonate; Neoplasms, Experimental; Neuroma; Pregnancy; Pregnancy, Animal; Rats

1978
Chemical and radiation induced late dominant lethal effects in mice.
    Mutation research, 1978, Volume: 54, Issue:3

    Topics: Animals; Ethyl Methanesulfonate; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Male; Mesylates; Mice; Mice, Inbred DBA; Mutagens; Pregnancy; Time Factors; X-Rays

1978
Dose and effect of methyl-2-benzimidazolylcarbamate in the "mammalian spot test", an in vivo method for the detection of genetic alterations in somatic cells of mice.
    Chemico-biological interactions, 1979, Volume: 26, Issue:1

    Topics: Alleles; Animals; Benzimidazoles; Carbamates; Color; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Gene Frequency; Genes; Hair; Heterozygote; Methods; Mutagens; Pregnancy; Rats

1979
[Mutagenicity test of antithyroid agent, methimazole--dominant lethal mutation test on male mice (author's transl)].
    The Journal of toxicological sciences, 1979, Volume: 4, Issue:2

    Topics: Animals; Body Weight; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Gestational Age; Male; Methimazole; Mice; Mitomycins; Mutagens; Organ Size; Pregnancy

1979
Dominant lethal studies with the halogenated olefins vinyl chloride and vinylidene dichloride in male CD-1 mice.
    Environmental health perspectives, 1977, Volume: 21

    Topics: Animals; Cyclophosphamide; Dichloroethylenes; Embryo Implantation; Environmental Exposure; Ethyl Methanesulfonate; Female; Fertility; Fetal Death; Genes, Dominant; Genes, Lethal; Hydrocarbons, Chlorinated; Male; Mice; Mice, Inbred Strains; Mutation; Pregnancy; Vinyl Chloride; Vinyl Compounds

1977
Dominant-lethal test results with known mutagens in two laboratories.
    Mutation research, 1977, Volume: 43, Issue:2

    Topics: Animals; Cyclophosphamide; Embryo Implantation; Ethyl Methanesulfonate; Female; Fetal Death; Laboratories; Male; Mechlorethamine; Mice; Mutagens; Pregnancy; Quality Control

1977
Proceedings: Pre-implantation loss in the dominant lethal assay.
    Mutation research, 1975, Volume: 29, Issue:2

    Topics: Animals; Embryonic Development; Ethyl Methanesulfonate; Female; Genes, Dominant; Genes, Lethal; Male; Mice; Mutagens; Pregnancy; Pregnancy, Animal

1975
Potentiation of ethyl methanesulfonate-induced germ cell mutagenesis and depression of glutathione in male reproductive tissues by 1,2-dibromoethane.
    Teratogenesis, carcinogenesis, and mutagenesis, 1990, Volume: 10, Issue:6

    Topics: Animals; Drug Synergism; Embryo Implantation; Ethyl Methanesulfonate; Ethylene Dibromide; Female; Fetal Death; Fetal Resorption; Genes, Dominant; Genes, Lethal; Genitalia, Male; Glutathione; Male; Mutagenesis; Mutagens; Pregnancy; Rats; Rats, Inbred F344; Spermatozoa

1990
Comparison of DNA alkylation, fragmentation, and repair in maternal and fetal tissues of pregnant rats treated with a single dose of ethyl methanesulfonate, ethyl-N-nitrosourea, N-nitrosodiethylamine, and methyl-N-nitrosourea.
    Teratogenesis, carcinogenesis, and mutagenesis, 1989, Volume: 9, Issue:3

    Topics: Alkylating Agents; Animals; Carcinogens; Chromatography; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Female; Fetus; Nitroso Compounds; Organ Specificity; Pregnancy; Rats; Rats, Inbred Strains; Time Factors

1989
In vitro developmental toxicity of five direct-acting alkylating agents in rodent embryos: structure-activity patterns.
    Teratology, 1989, Volume: 40, Issue:3

    Topics: Alkylating Agents; Analysis of Variance; Animals; Brain; Dose-Response Relationship, Drug; Embryo, Mammalian; Ethyl Methanesulfonate; Ethylnitrosourea; Female; In Vitro Techniques; Maternal-Fetal Exchange; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Pregnancy; Rats; Rats, Inbred Strains

1989
Comparison of behaviors for detection of heritable mutations.
    Teratogenesis, carcinogenesis, and mutagenesis, 1988, Volume: 8, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Ethyl Methanesulfonate; Female; Litter Size; Male; Mice; Mice, Inbred ICR; Motor Activity; Mutation; Pregnancy; Reference Values

1988
Fetal anomalies produced subsequent to treatment of zygotes with ethylene oxide or ethyl methanesulfonate are not likely due to the usual genetic causes.
    Mutation research, 1989, Volume: 210, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Cleavage Stage, Ovum; Cytogenetics; Embryo Transfer; Ethyl Methanesulfonate; Ethylene Oxide; Female; Fetal Death; Mice; Pregnancy; Zygote

1989
Embryotoxicity induced by alkylating agents. Some methodological aspects of DNA alkylation studies in murine embryos using ethylmethanesulfonate.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 1987, Volume: 42, Issue:5

    Topics: Adenine; Alkylation; Animals; DNA; Embryo, Mammalian; Ethyl Methanesulfonate; Female; Guanine; Liver; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Pregnancy; Spectrophotometry, Infrared; Structure-Activity Relationship

1987
Mutagen-induced fetal anomalies and death following treatment of females within hours after mating.
    Mutation research, 1988, Volume: 199, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Cleavage Stage, Ovum; Embryo Implantation; Ethyl Methanesulfonate; Ethylene Oxide; Ethylnitrosourea; Female; Fetal Death; Mice; Mutagens; Oocytes; Ovum; Pregnancy; Triethylenemelamine; Zygote

1988
Induction of congenital malformations in the offspring of mutagen treated mice.
    Progress in clinical and biological research, 1986, Volume: 209B

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Ethyl Methanesulfonate; Ethylnitrosourea; Female; Mice; Mice, Inbred C3H; Mutagens; Pregnancy; Prenatal Exposure Delayed Effects

1986
Germ-cell mutagenesis and GSH depression in reproductive tissue of the F-344 rat induced by ethyl methanesulfonate.
    Mutation research, 1985, Volume: 144, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Female; Fetal Death; Genes, Dominant; Genes, Lethal; Genitalia, Male; Glutathione; Litter Size; Male; Pregnancy; Rats; Rats, Inbred F344; Spermatogenesis

1985