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ethyl methanesulfonate and Leukemia L5178

ethyl methanesulfonate has been researched along with Leukemia L5178 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199012 (52.17)18.7374
1990's7 (30.43)18.2507
2000's4 (17.39)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shuai, PQ; Wang, YJ; Zhang, LS1
Nakamura, N; Okada, S1
Shiomi, T; Tobari, I; Tsuji, H1
Okada, S; Sakai, K1
Aaron, CS; Glickman, BW; Knaap, AG; Mohn, GR; Natarajan, AT; Tates, AD; van Zeeland, AA1
Glickman, BW; Mohn, GR; van Zeeland, AA1
Hieda-Shiomi, N; Sato, K; Shiomi, T2
Arlett, CF; Burns, VW; Hill, R; Lehmann, AR; Rogers, AM1
Stadler, JK; Vaughan, VL1
Hayashi, M; Honma, M; Matsuoka, A; Sofuni, T; Suzuki, T; Zhang, LS1
Davies, MJ; Phillips, BJ; Rumsby, PC1
Eckert, I; Schulz, WA; Stopper, H; Wagener, P1
Lutz, WK; Mueller, SO; Stopper, H1
Arlett, CF; Cole, J; Lasne, C1
Frieauff, W; Hartmann, A; Suter, W1
Lutz, WK; Stopper, H1
Brabbs, C; Davies, S; Henderson, L; Ransome, S; Tinner, A1
Campbell, J; Clare, CB; Cole, H; Garner, RC; Harrington, DH; Kennelly, JC; Lane, MP1
Cattanach, PJ; Combes, RD; Edwards, IW; Howgate, S; McBride, D; McGregor, DB; Riach, CG; Shepherd, W1
Clay, P; Cross, MF1
Beer, JZ; Evans, HH; Horng, MF1
Paeratakul, U; Taylor, MW1

Trials

2 trial(s) available for ethyl methanesulfonate and Leukemia L5178

ArticleYear
Induction of mutations in mouse lymphoma L5178Y cells by ethylmethanesulphonate, benzidine and benzo[a]pyrene.
    Mutagenesis, 1990, Volume: 5 Suppl

    Topics: Animals; Benzidines; Benzo(a)pyrene; Biotransformation; Cell Survival; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Leukemia L5178; Mice; Microsomes, Liver; Multicenter Studies as Topic; Mutagenicity Tests; Mutagens; Mutation; Thymidine Kinase; Tumor Cells, Cultured

1990
Microwell mutation assays: evaluation of ethylmethanesulphonate, benzo[a]pyrene and benzidine using the tk locus in L5178Y mouse lymphoma cells.
    Mutagenesis, 1990, Volume: 5 Suppl

    Topics: Animals; Benzidines; Benzo(a)pyrene; Biotransformation; Cell Survival; Ethyl Methanesulfonate; Leukemia L5178; Mice; Microsomes, Liver; Multicenter Studies as Topic; Mutagenicity Tests; Mutagens; Thymidine Kinase; Time Factors; Tumor Cells, Cultured

1990

Other Studies

21 other study(ies) available for ethyl methanesulfonate and Leukemia L5178

ArticleYear
[TK locus mutation assay: comparison of L5178Y and TK6 cell lines].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2004, Volume: 35, Issue:5

    Topics: Animals; Cell Line, Tumor; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Mitomycin; Mutagenicity Tests; Mutation; Thymidine Kinase

2004
Mutations resistant to bromodeoxyuridine in mouse lymphoma cells selected by repeated exposure to EMS. Characteristics of phenotypic instability and reversion to HAT resistance by 5-azacytidine.
    Mutation research, 1983, Volume: 111, Issue:3

    Topics: Animals; Azacitidine; Bromodeoxyuridine; DNA Replication; Drug Resistance; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Phenotype; Thymidine Kinase

1983
High induction of sister chromatid exchange and chromosome aberration by 5-bromodeoxyuridine in an ethylmethane-sulfonate-sensitive mouse lymphoma cell mutant (ES 4).
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Survival; Chromosome Aberrations; Deoxyribonucleosides; Ethyl Methanesulfonate; Leukemia L5178; Mice; Mutation; Sister Chromatid Exchange

1984
An alkaline separation method for detection of small amount of DNA damage.
    Journal of radiation research, 1981, Volume: 22, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Cells, Cultured; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Leukemia L5178; Methods; Mice

1981
Molecular dosimetry of the chemical mutagen ethyl methanesulfonate: quantitative comparison of mutation induction in Escherichia coli, V79 Chinese hamster cells and L5178Y mouse lymphoma cells, and some cytological results in vitro and in vivo.
    Mutation research, 1980, Volume: 69, Issue:2

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Gene Frequency; Leukemia L5178; Lung; Mice; Mutagens

1980
Influence of experimental conditions and DNA repair ability on EMS-induced mutagenesis and DNA binding in Escherichia coli K12: comparison with mammalian cell mutagenesis.
    Mutation research, 1982, Feb-22, Volume: 92, Issue:1-2

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA Repair; DNA, Bacterial; Dose-Response Relationship, Drug; Escherichia coli; Ethyl Methanesulfonate; Leukemia L5178; Lung; Mutagens; Mutation; Phenotype

1982
A novel mutant of mouse lymphoma cells sensitive to alkylating agents and caffeine.
    Mutation research, 1982, Volume: 103, Issue:1

    Topics: Alkylating Agents; Animals; Caffeine; Cell Survival; Ethyl Methanesulfonate; Leukemia L5178; Leukemia, Experimental; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Mice; Mitomycins; Mutagenicity Tests; Mutagens; Mutation; Ultraviolet Rays

1982
Isolation of UV-sensitive mutants of mouse L5178Y cells by a cell suspension spotting method.
    Somatic cell genetics, 1982, Volume: 8, Issue:3

    Topics: Animals; Cell Division; Clone Cells; Ethyl Methanesulfonate; Genetic Complementation Test; Leukemia L5178; Leukemia, Experimental; Methods; Methylnitronitrosoguanidine; Mice; Mutation; Ultraviolet Rays

1982
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
    Mutation research, 1980, Volume: 69, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cytarabine; Drug Resistance; Ethidium; Ethyl Methanesulfonate; Leukemia L5178; Leukemia, Experimental; Mice; Mutagens; Mutation; Thymidine

1980
Isolation and genetic characterization of dibucaine-resistant variants of a mouse lymphocytic cell line.
    Experimental cell research, 1980, Volume: 130, Issue:1

    Topics: Animals; Benzocaine; Cell Division; Cell Line; Dibucaine; Dose-Response Relationship, Drug; Drug Resistance; Ethyl Methanesulfonate; Hybrid Cells; Leukemia L5178; Lymphocytes; Mice; Mutation; Procaine; Tetracaine

1980
A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test.
    Mutation research, 1995, Volume: 347, Issue:3-4

    Topics: Animals; B-Lymphocytes; Cell Line; Cell Survival; Demecolcine; Ethyl Methanesulfonate; Humans; Leukemia L5178; Lymphoma; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Mutagens; Tumor Cells, Cultured; Vincristine; X-Rays

1995
Molecular analysis of mutations at the tk locus of L5178Y mouse-lymphoma cells induced by ethyl methanesulphonate and mitomycin C.
    Mutation research, 1993, Volume: 290, Issue:2

    Topics: Animals; Blotting, Northern; Blotting, Southern; DNA Mutational Analysis; Ethyl Methanesulfonate; Gene Deletion; Leukemia L5178; Mice; Mitomycin; Mutagenesis; Mutagenicity Tests; Mutagens; Point Mutation; Thymidine Kinase; Tumor Cells, Cultured

1993
Formation of micronuclei and inhibition of topoisomerase II in the comet assay in mammalian cells with altered DNA methylation.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1997, Volume: 143

    Topics: Amsacrine; Animals; Azacitidine; Carcinoma, Embryonal; Cell Differentiation; DNA Methylation; DNA, Neoplasm; Enzyme Inhibitors; Ethyl Methanesulfonate; In Situ Hybridization; Kinetochores; Leukemia L5178; Mammals; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1997
Supra-additive genotoxicity of a combination of gamma-irradiation and ethyl methanesulfonate in mouse lymphoma L5178Y cells.
    Mutagenesis, 2000, Volume: 15, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Gamma Rays; Leukemia L5178; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Tumor Cells, Cultured

2000
The tumour promoter TPA does not affect mutation to ouabain resistance in L5178Y mouse lymphoma cells.
    Carcinogenesis, 1980, Volume: 1, Issue:7

    Topics: Animals; Carcinogens; Drug Resistance; Ethyl Methanesulfonate; Leukemia L5178; Mice; Mutagenesis; Mutagens; Mutation; Ouabain; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays

1980
Automatic analysis of slides processed in the Comet assay.
    Mutagenesis, 2001, Volume: 16, Issue:2

    Topics: Animals; Anthracenes; Cells, Cultured; Comet Assay; Cricetinae; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Humans; Image Processing, Computer-Assisted; Leukemia L5178; Male; Mice; Microscopy; Mutagens; Rats; Rats, Wistar

2001
Induction of micronuclei in human cell lines and primary cells by combination treatment with gamma-radiation and ethyl methanesulfonate.
    Mutagenesis, 2002, Volume: 17, Issue:2

    Topics: Animals; DNA Damage; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Female; Fetus; Fibroblasts; Gamma Rays; Humans; Leukemia L5178; Lung; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Mutation; Pregnancy; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
The mutagenic activity of ethylmethanesulphonate, benzidine and benzo[a]pyrene at the hprt locus of wild-type L5178Y mouse lymphoma cells.
    Mutagenesis, 1990, Volume: 5 Suppl

    Topics: Animals; Benzidines; Benzo(a)pyrene; Biotransformation; Cell Survival; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Leukemia L5178; Mice; Microsomes, Liver; Mutagenicity Tests; Mutagens; Mutation; Tumor Cells, Cultured

1990
Studies on the activities of benzo[a]pyrene, benzidine and ethyl methanesulphonate in the L5178Y TK +/- mouse lymphoma mutagenicity assay using standardized and non-standardized protocols.
    Mutagenesis, 1990, Volume: 5 Suppl

    Topics: Animals; Benzidines; Benzo(a)pyrene; Biotransformation; Cell Count; Ethyl Methanesulfonate; In Vitro Techniques; Leukemia L5178; Mice; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred F344; Thymidine Kinase; Time Factors; Tumor Cells, Cultured

1990
Lethal and mutagenic effects of radiation and alkylating agents on two strains of mouse L5178Y cells.
    Mutation research, 1986, Volume: 161, Issue:1

    Topics: Animals; Cell Survival; Dose-Response Relationship, Radiation; Ethyl Methanesulfonate; Hypoxanthine Phosphoribosyltransferase; Leukemia L5178; Leukemia, Experimental; Methylnitrosourea; Mice; Mutation; Sodium-Potassium-Exchanging ATPase; Ultraviolet Rays; X-Rays

1986
Selection and characterization of APRT heterozygotes of mouse L-5178Y cells.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt A

    Topics: Adenine Phosphoribosyltransferase; Animals; Ethyl Methanesulfonate; Genetic Variation; Heterozygote; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Nucleic Acid Hybridization; Pentosyltransferases

1986