ethyl-cellulose and Chronic-Disease

ethyl-cellulose has been researched along with Chronic-Disease* in 2 studies

Trials

1 trial(s) available for ethyl-cellulose and Chronic-Disease

ArticleYear
Development and evaluation of acrylic strips of metronidazole for the therapy of periodontal disease.
    Die Pharmazie, 1995, Volume: 50, Issue:2

    Topics: Administration, Topical; Cellulose; Chronic Disease; Dental Plaque; Dibutyl Phthalate; Humans; Methylmethacrylates; Metronidazole; Periodontal Diseases

1995

Other Studies

1 other study(ies) available for ethyl-cellulose and Chronic-Disease

ArticleYear
Gentamicin-impregnated chitosan/nanohydroxyapatite/ethyl cellulose microspheres granules for chronic osteomyelitis therapy.
    Journal of biomedical materials research. Part A, 2010, Jun-01, Volume: 93, Issue:3

    In this article gentamicin (GM) impregnated microspheres were used to extend the drug release time for the treatment of chronic osteomyelitis. The granules were prepared in solution and consisted of nanohydroxyapatite (nHA), chitosan (CS) and GM loaded ethyl cellulose (EC) microspheres. A rabbit model with chronic osteomyelitis was made by using staphylococcus aureus and morrhuate sodium and special inspection methods were used to test the curative effects of the granules, such as microbiological investigations, tissue, and X-ray observations. The granules were provided with excellent drug release properties, 49 days in vitro and 45 days in vivo, moreover, they showed almost no cytotoxic for fibroblast and osteoblast. The findings indicated that the GM-impregnated CS/nHA/EC microspheres granules showed outstanding curative effect. Generally, it can be concluded that the granules containing GM impregnated microspheres may be used effectively in the treatment of the chronic osteomyelitis.

    Topics: Animals; Cell Death; Cell Survival; Cellulose; Chitosan; Chronic Disease; Durapatite; Fibroblasts; Gentamicins; Humans; Implants, Experimental; Microspheres; Nanostructures; Osteoblasts; Osteomyelitis; Rabbits; Radiography; Rats; Rats, Wistar; Staphylococcus aureus; Tibia

2010